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Author | : David D'Argenio |
Publisher | : Springer Science & Business Media |
Total Pages | : 202 |
Release | : 2013-06-29 |
Genre | : Medical |
ISBN | : 147579021X |
Download Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis Book in PDF, ePub and Kindle
This volume records the proceedings of the Workshop on Advanced Meth ods of Pharmacokinetic and Pharmacodynamic Systems Analysis, organized by the Biomedical Simulations Resource in May 1990. The meeting brought together over 120 investigators from a number of disciplines, including clinical pharmacology, clinical pharmacy, pharmaceutical science, biomathematics, statistics and biomed ical engineering with the purpose of providing a high-level forum to facilitate the exchange of ideas between basic and clinical research scientists, experimentalists and modelers working on problems in pharmacokinetics and pharmacodynamics. It has been my experience that in many areas of biomedical research, when a meeting of this type is held, the general attitude of those experimentalists willing to attend is one of extreme skepticism: as a group they feel that mathematical modeling has little to offer them in furthering their understanding of the particular biological processes they are studying. This is certainly not the prevailing view when the topic is pharmacokinetics and drug response. Quite the contrary, the use of mathemati cal modeling and associated data analysis and computational methods has been a central feature of pharmacokinetics almost from its beginnings. In fact, the field has borrowed techniques of modeling from other disciplines including applied math ematics, statistics and engineering, in an effort to better describe and understand the processes of drug disposition and drug response.
Author | : |
Publisher | : |
Total Pages | : |
Release | : 1989 |
Genre | : Pharmacokinetics |
ISBN | : |
Download Workshop on Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis Book in PDF, ePub and Kindle
Author | : Marcos Briano |
Publisher | : Springer Science & Business Media |
Total Pages | : 311 |
Release | : 2004-03-31 |
Genre | : Medical |
ISBN | : 1402078048 |
Download Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis Book in PDF, ePub and Kindle
Advanced Methods of Pharmacokinetic and Pharmocodynamic Systems Analysis Volume 3 is vital to professionals and academicians working in drug development and bioengineering. Both basic and clinical scientists will benefit from this work. This book contains chapters by leading researchers in pharmacokinetic/pharmacodynamic modeling and will be of interest to anyone involved with the application of pharmacokinetic and pharmacodynamics to drug development. The use of mathematical modeling and associated computational methods is central to the study of the absorption, distribution and elimination of therapeutic drugs (pharmacokinetics) and to understanding how drugs produce their effects (pharmacodynamics). From its inception, the field of pharmacokinetics and pharmacodynamics has incorporated methods of mathematical modeling, simulation and computation in an effort to better understand and quantify the processes of uptake, disposition and action of therapeutic drugs. These methods for pharmacokinetic/pharmacodynamic systems analysis impact all aspects of drug development. In vitro, animal and human testing, as well as drug therapy are all influenced by these methods. Modeling methodologies developed for studying pharmacokinetic/ pharmacodynamic processes confront many challenges. This is related in part to the severe restrictions on the number and type of measurements that are available from laboratory experiments and clinical trials, as well as the variability in the experiments and the uncertainty associated with the processes themselves. The contributions are organized in three main areas: Mechanism-Based PK/PD, Pharmacometrics and Pharmacotherapy. Both professionals and academics will profit from this extensive work.
Author | : Marcos Briano |
Publisher | : Springer |
Total Pages | : 218 |
Release | : 1995-07-31 |
Genre | : Medical |
ISBN | : 9780306450181 |
Download Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis Book in PDF, ePub and Kindle
Proceedings of the 1993 Biomedical Simulations Research Workshop, held in Los Angeles, California, May 21-22, 1993
Author | : David Z. D'Argenio |
Publisher | : |
Total Pages | : 217 |
Release | : 1995 |
Genre | : Drugs |
ISBN | : |
Download Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis, Volume 2 Book in PDF, ePub and Kindle
Author | : University of California, San Francisco |
Publisher | : |
Total Pages | : |
Release | : 1997 |
Genre | : Drugs |
ISBN | : |
Download Workshop on Advanced Methods in Pharmacokinetics and Pharmacodynamics Book in PDF, ePub and Kindle
Author | : National Library of Medicine (U.S.) |
Publisher | : |
Total Pages | : 666 |
Release | : 1992 |
Genre | : Medicine |
ISBN | : |
Download Current Catalog Book in PDF, ePub and Kindle
First multi-year cumulation covers six years: 1965-70.
Author | : Peter L. Bonate |
Publisher | : Springer Science & Business Media |
Total Pages | : 634 |
Release | : 2011-07-01 |
Genre | : Medical |
ISBN | : 1441994858 |
Download Pharmacokinetic-Pharmacodynamic Modeling and Simulation Book in PDF, ePub and Kindle
This is a second edition to the original published by Springer in 2006. The comprehensive volume takes a textbook approach systematically developing the field by starting from linear models and then moving up to generalized linear and non-linear mixed effects models. Since the first edition was published the field has grown considerably in terms of maturity and technicality. The second edition of the book therefore considerably expands with the addition of three new chapters relating to Bayesian models, Generalized linear and nonlinear mixed effects models, and Principles of simulation. In addition, many of the other chapters have been expanded and updated.
Author | : National Library of Medicine (U.S.) |
Publisher | : |
Total Pages | : 1184 |
Release | : 1992 |
Genre | : Medicine |
ISBN | : |
Download National Library of Medicine Current Catalog Book in PDF, ePub and Kindle
Author | : Neal R. Cutler |
Publisher | : John Wiley & Sons |
Total Pages | : 514 |
Release | : 1994-09-20 |
Genre | : Medical |
ISBN | : 9780471950523 |
Download Pharmacodynamics and Drug Development Book in PDF, ePub and Kindle
Contains essential facts and concepts spanning many of the important drug classes. Features an authoritative section on general methodology and regulatory issues. The molecular biology and pharmacology of key receptor types are considered along with the detailed pharmacodynamics of a wide range of therapeutic drug groups.