Why Do We Age PDF Download
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| Author | : David A. Sinclair |
| Publisher | : Atria Books |
| Total Pages | : 432 |
| Release | : 2019-09-10 |
| Genre | : Science |
| ISBN | : 1501191977 |
Download Lifespan Book in PDF, ePub and Kindle
A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.” —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.” This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger. Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.
| Author | : Leonard Hayflick |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 1996 |
| Genre | : Aging |
| ISBN | : 9780345401557 |
Download How and why We Age Book in PDF, ePub and Kindle
"How long can humans live? Is immortality possible? Just what is the aging process? The aging and inevitable death of the human body have inspired more myths and outrageous quackery than anything else subject to scientific inquiry. . . . Now comes a most fascinating book, insightful and scholarly, to provide what answers have emerged so far." --San Francisco Chronicle Here, at last, preeminent cell biologist Leonard Hayflick presents the truth about human aging. Based on more than thirty years of pioneering research in the field, How and Why We Age explores not only how our major biological systems change as we grow older, but also examines the intangible alterations in our modes of thinking and feeling, our moods and sexual desires, our personality traits and our memories. With the immediacy of the latest scientific discoveries, Dr. Hayflick explains how aging affects every part of the body, and dispels many of the most persistent aging myths, to show that: * Hearts do not naturally get weaker with age. * Regular exercise and a low-fat diet won't slow aging. * Curing cancer would only add two years to the average sixty-five-year-old American life. Curing heart disease, however would add fourteen years. * Only five percent of people over the age of sixty-five are in nursing homes * No human has lived--or probably can live--past 120 years. Gracefully written, clearly organized, and packed with essential facts and statistics, How and Why We Age is a landmark study of the aging process for readers of all ages. "Written in clear, nontechnical language, it is an excellent introduction to the scientific and demographic literature on this multifacetedsubject." --Nature
| Author | : Steven N. Austad |
| Publisher | : Wiley |
| Total Pages | : 0 |
| Release | : 1999-03-25 |
| Genre | : Science |
| ISBN | : 9780471296461 |
Download Why We Age Book in PDF, ePub and Kindle
Why has the life span of the average American increased from 48 to 75 years in this century alone? . . . If the body is a machine that simply wears out, why do some cells seem immortal? . . . Is there an aging gene? And can we control it? . . . Can antioxidants and hormone therapy actually slow the aging process and extend life? Steven Austad s compelling book investigates the history, the theories, and the personalities behind the quest to understand the nature of aging. Here is hard evidence from the front lines of research that science is finally closing in on the fundamental processes of human biology and life. "Austad s book can be read with pleasure and profit by any intelligent person with a smattering of biological knowledge." Science "In this clear, engrossing overview, Austad takes the sting out of a subject that will ultimately capture us all." Publishers Weekly "Why We Age is remarkably rigorous in its analysis and thorough scope. . . . A comprehensive examination of its topic." Science Editors, Amazon.com "The problem with long life is that one keeps getting older; here s an able and clearly written summary of the latest theories on why we age and what might be done to ameliorate the process." Kirkus Reviews
| Author | : Andrew Steele |
| Publisher | : Anchor |
| Total Pages | : 353 |
| Release | : 2021-03-23 |
| Genre | : Science |
| ISBN | : 0385544936 |
Download Ageless Book in PDF, ePub and Kindle
“A fascinating look at how scientists are working to help doctors treat the aging process itself, helping us all to lead longer, healthier lives.” —Sanjay Gupta, MD Aging—not cancer, not heart disease—is the underlying cause of most human death and suffering. The same cascade of biological changes that renders us wrinkled and gray also opens the door to dementia and disease. We work furiously to conquer each individual disease, but we never think to ask: Is aging itself necessary? Nature tells us it is not: there are tortoises and salamanders who are spry into old age and whose risk of dying is the same no matter how old they are, a phenomenon known as “biological immortality.” In Ageless, Andrew Steelecharts the astounding progress science has made in recent years to secure the same for humans: to help us become old without getting frail, to live longer without ill health or disease.
| Author | : Alex Comfort |
| Publisher | : CreateSpace |
| Total Pages | : 274 |
| Release | : 2010-11-25 |
| Genre | : |
| ISBN | : 9781456392420 |
Download The Biology of Senescence Book in PDF, ePub and Kindle
The Biology of Senescence
| Author | : Leonard Hayflick |
| Publisher | : |
| Total Pages | : 408 |
| Release | : 1994 |
| Genre | : Family & Relationships |
| ISBN | : |
Download How and why We Age Book in PDF, ePub and Kindle
Preeminent cell biologist Leonard Hayflick reveals the results of more than thirty years of pioneering research in the field of aging. Gracefully written, clearly organized, and packed with essential facts and statistics, "How and Why We Age" is a landmark study of the aging process for readers of all ages.
| Author | : Trygve O. Tollefsbol |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 462 |
| Release | : 2009-11-11 |
| Genre | : Medical |
| ISBN | : 1441906398 |
Download Epigenetics of Aging Book in PDF, ePub and Kindle
Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.
| Author | : John J. Medina |
| Publisher | : Cambridge University Press |
| Total Pages | : 352 |
| Release | : 1997-08-13 |
| Genre | : Family & Relationships |
| ISBN | : 9780521594561 |
Download The Clock of Ages Book in PDF, ePub and Kindle
Anyone who has watched a wrinkle slowly gouge their face like a strip mine, or has been disturbed by a loss of memory, has uncomfortably confronted the human ageing process. The inexorable march of time on our bodies begs an important question: why do we have to grow old? Written in everyday language, The Clock of Ages takes us on a tour of the ageing human body - all from a research scientist's point of view. From the deliberate creation of organisms that live three times their natural span to the isolation of human genes that may allow us to do the same, The Clock of Ages also examines the latest discoveries in geriatric genetics. Sprinkled throughout the pages are descriptions of the aging of many historical figures, such as Florence Nightingale, Jane Austen, Bonaparte and Casanova. These stories underscore the common bond that unites us all: they aged, even as we do. The Clock of Ages tells you why.
| Author | : Priscilla Ebersole |
| Publisher | : Mosby Incorporated |
| Total Pages | : 727 |
| Release | : 2008 |
| Genre | : Medical |
| ISBN | : 9780323047302 |
Download Toward Healthy Aging Book in PDF, ePub and Kindle
As the most comprehensive resource on health promotion and maintenance for older adults and their families and caregivers, Toward Healthy Aging, 7th Edition includes the most current information you need to provide effective holistic care, promote healthy lifestyle choices, and address end-of-life issues. Grounded in the core competencies recommended by the AACN in collaboration with the Hartfound Institute for Geriatric Nursing and using Maslow's hierarchy of needs, this book includes complete coverage of both common and uncommon conditions in the older adult. Towards Healthy Aging also highlights key aging issues with sections devoted to basic physiologic needs, safety and security, the need to belong, self-esteem, and self-actualization. A strong focus on health and wellness emphasizes a positive approach to aging. Disease processes are discussed in the context of healthy adaptation, nursing support, and responsibilities. Careful attention to age, cultural, and gender differences are integrated throughout to help you remember these important considerations when caring for older adults. Up-to-date content on AIDS provides important information on addressing this growing concern among older adults. Consistent chapter is organization with objectives, case studies, critical thinking questions, research, and study questions make information easy to find and use. Assessment guidelines are incorporated throughout in helpful tables, boxes, and forms for quick access. Case studies at the end of most chapters explore realistic patient care scenarios to help you expand your knowledge and understanding. Resource lists and appendices provide opportunities for further research and study. With over 200 illustrations, the full-color design is engaging and easy to read. Healthy People 2010 boxes address healthy aging considerations. Evidence-Based Practice boxes help you incorporate the latest research findings into practice and advise you on how to avoid potentially harmful practices. A Nutritional Needs chapter includes the most current nutritional guidelines for older adults to help you better address patients' nutritional needs. Includes the latest scales and guidelines for assessing the gerontologic patient in the Health Assessment in Gerontological Nursing chapter. Expanded coverage of end-of-life issues helps you meet the needs of older adults and their families and caregivers during this difficult transition. Economics of aging discussions help you better understand the financial challenges your patients may face. The latest pharmacologic and nonpharmacologic pain management information helps you reduce pain and discomfort for your patients and helps you provide more effective care.
| Author | : Judy Helen Ford |
| Publisher | : |
| Total Pages | : 212 |
| Release | : 2019-12-10 |
| Genre | : |
| ISBN | : 9781674558936 |
Download Why We Age Book in PDF, ePub and Kindle
'Why we age' explains the biology in an all-inclusive way for the first time. Judy Ford PhD is a geneticist/cell biologist who herself has contributed some significant research in the field of aging. In this book, Judy puts together many of the currently disparate theories and explains how the various 'theories of ageing' need to be considered together. Because of her unusual cross-disciplinary knowledge, she is able to explain how all the pieces of the complex puzzle fit together and make some (sometimes unusual) recommendations for healthier lifestyles.Despite the need to use some medical and scientific terminology, this is book can be easily understood by any intelligent person. It is particularly suitable for anyone with some knowledge of the science of health, and doctors, dentists, nurses, scientists have all found it extremely interesting.A reader (Mary's) perspective: I really enjoyed reading "Why we age - Solving the puzzle of aging" by Dr Judy Ford. Even though I do not have a background in Science, the unfamiliar terms in Section 1 were so clearly and promptly explained in the text that I felt confident to continue reading and understand the solution to the puzzle. The insights promised in Part B possibly causing various disease across the world were thought provoking and the recommendations in Part C can be trusted. In this book, Dr Judy Ford (the academic) becomes Judy Ford (just another woman going through the aging process) who comforts and encourages us all to be more positive and proactive in caring for our own aging bodies and minds. Judy's final words of advice clearly come from her sound empirical evidence and respected research, as much as her personal life experience, keen sense of humor and a refreshing "good old dose of common sense"
