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Whole Genome Amplification of DNA from Residual Cells Left By Incidental Contact

Whole Genome Amplification of DNA from Residual Cells Left By Incidental Contact
Author:
Publisher:
Total Pages: 13
Release: 2003
Genre:
ISBN:

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Typically, the number of genetic analyses performed on a sample of DNA has been limited by the amount of starting material. For example, the small quantity of DNA obtained from the cells within a fingerprint meant that only a five to ten reactions could be performed off a single sample. We demonstrate a process wherein total genomic DNA is amplified before forensic typing analysis. The process requires as few as 8 cells and produces sufficient material for up to 20,000 subsequent PCR reactions. The technique is particularly useful to enhance current methods of latent print analysis and has been shown to be compatible with common forensic print visualization and removal techniques including dye staining and powders.


Index Medicus

Index Medicus
Author:
Publisher:
Total Pages: 2454
Release: 2004
Genre: Medicine
ISBN:

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Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.


Forensic DNA Profiling Protocols

Forensic DNA Profiling Protocols
Author: Patrick J. Lincoln
Publisher: Springer Science & Business Media
Total Pages: 617
Release: 1998-01-22
Genre: Medical
ISBN: 0896034437

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This state-of-the-art collection of easily reproducible methods includes all of the major techniques of DNA analysis currently used in forensic identity testing. The methods include the recovery of DNA from a large range of sample types, analysis of DNA as single and multi-locus VNTR probes, PCR amplification of STR and other loci, and mitochondrial sequencing. The expert scientists writing here -- many from laboratories around the world -- also discuss how to interpret the results in cases of unknown identity and disputed parentage.-- Covers all steps from extraction of human DNA through to analysis and interpretation-- Takes advantage of new methodologies such as capillary electrophoresis-- Clear step-by-step instructions ensure unfailing reproducibility.


Genomics Protocols

Genomics Protocols
Author: Michael P. Starkey
Publisher: Springer Science & Business Media
Total Pages: 537
Release: 2008-02-03
Genre: Medical
ISBN: 159259235X

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We must unashamedly admit that a large part of the motivation for editing Genomics Protocols was selfish. The possibility of assembling in a single volume a unique and comprehensive collection of complete protocols, relevant to our work and the work of our colleagues, was too good an opportunity to miss. We are pleased to report, however, that the outcome is something of use not only to those who are experienced practitioners in the genomics field, but is also valuable to the larger community of researchers who have recognized the potential of genomics research and may themselves be beginning to explore the technologies involved. Some of the techniques described in Genomics Protocols are clearly not restricted to the genomics field; indeed, a prerequisite for many procedures in this discipline is that they require an extremely high throughput, beyond the scope of the average investigator. However, what we have endeavored here to achieve is both to compile a collection of procedures concerned with geno- scale investigations and to incorporate the key components of “bottom-up” and “top-down” approaches to gene finding. The technologies described extend from those traditionally recognized as coming under the genomics umbrella, touch on proteomics (the study of the expressed protein complement of the genome), through to early therapeutic approaches utilizing the potential of genome programs via gene therapy (Chapters 27–30).


Molecular Epidemiology

Molecular Epidemiology
Author: Paul A. Schulte
Publisher: Academic Press
Total Pages: 609
Release: 2012-12-02
Genre: Medical
ISBN: 0323138578

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This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.


Strengthening Forensic Science in the United States

Strengthening Forensic Science in the United States
Author: National Research Council
Publisher: National Academies Press
Total Pages: 348
Release: 2009-07-29
Genre: Law
ISBN: 0309142393

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Scores of talented and dedicated people serve the forensic science community, performing vitally important work. However, they are often constrained by lack of adequate resources, sound policies, and national support. It is clear that change and advancements, both systematic and scientific, are needed in a number of forensic science disciplines to ensure the reliability of work, establish enforceable standards, and promote best practices with consistent application. Strengthening Forensic Science in the United States: A Path Forward provides a detailed plan for addressing these needs and suggests the creation of a new government entity, the National Institute of Forensic Science, to establish and enforce standards within the forensic science community. The benefits of improving and regulating the forensic science disciplines are clear: assisting law enforcement officials, enhancing homeland security, and reducing the risk of wrongful conviction and exoneration. Strengthening Forensic Science in the United States gives a full account of what is needed to advance the forensic science disciplines, including upgrading of systems and organizational structures, better training, widespread adoption of uniform and enforceable best practices, and mandatory certification and accreditation programs. While this book provides an essential call-to-action for congress and policy makers, it also serves as a vital tool for law enforcement agencies, criminal prosecutors and attorneys, and forensic science educators.


Molecular Genetic Pathology

Molecular Genetic Pathology
Author: Liang Cheng
Publisher: Springer
Total Pages: 1136
Release: 2013-03-05
Genre: Medical
ISBN: 9781461447993

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Molecular Genetic Pathology, Second Edition presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology. Fully updated in each area and expanded to include identification of new infectious agents (H1N1), new diagnostic biomarkers and biomarkers for targeted cancer therapy. This edition is also expanded to include the many new technologies that have become available in the past few years such as microarray (AmpliChip) and high throughput deep sequencing, which will certainly change the clinical practice of molecular genetic pathology. Part I examines the clinical aspects of molecular biology and technology, genomics. Poharmacogenomics and proteomics, while Part II covers the clinically relevant information of medical genetics, hematology, transfusion medicine, oncology, and forensic pathology. Supplemented with many useful figures and presented in a helpful bullet-point format, Molecular Genetic Pathology, Second Edition provides a unique reference for practicing pathologists, oncologists, internists, and medical genetisists. Furthermore, a book with concise overview of the field and highlights of clinical applications will certainly help those trainees, including pathology residents, genetics residents, molecular pathology fellows, internists, hematology/oncology fellows, and medical technologists in preparing for their board examination/certification.


Directory of Graduate Research

Directory of Graduate Research
Author: American Chemical Society. Committee on Professional Training
Publisher:
Total Pages: 1932
Release: 2005
Genre: Biochemistry
ISBN:

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Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.


Whole Genome Amplification

Whole Genome Amplification
Author: Simon Hughes
Publisher: Methods Express (Paperback)
Total Pages: 224
Release: 2005
Genre: Medical
ISBN:

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Whole genome amplification generates microgram quantities of genomic DNA starting from a sample of as little as a few femtograms and so is a vital technique when sample material is limited, as well as for high-throughput assays. Whole Genome Amplification: Methods Expressis a comprehensive up-to-date laboratory manual for this key technique. It provides detailed step-by-step protocols as well as hints and tips for success and troubleshooting, taking readers through all aspects of whole genome amplification. This book is an essential practical guide for any researcher currently using PCR for genomic amplification or who wishes to do so in future.


Genomic Medicine

Genomic Medicine
Author: Dhavendra Kumar
Publisher: Oxford Monographs on Medical G
Total Pages: 853
Release: 2014-10-15
Genre: Medical
ISBN: 019989602X

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Preceded by Genomics and clinical medicine / edited by Dhavendra Kumar. [First edition]. 2008.