Viral Molecular Machines PDF Download
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Author | : Michael G. Rossmann |
Publisher | : Springer Science & Business Media |
Total Pages | : 685 |
Release | : 2012-02-02 |
Genre | : Medical |
ISBN | : 1461409802 |
Download Viral Molecular Machines Book in PDF, ePub and Kindle
This book will contain a series of solicited chapters that concern with the molecular machines required by viruses to perform various essential functions of virus life cycle. The first three chapters (Introduction, Molecular Machines and Virus Architecture) introduce the reader to the best known molecular machines and to the structure of viruses. The remainder of the book will examine in detail various stages of the viral life cycle. Beginning with the viral entry into a host cell, the book takes the reader through replication of the genome, synthesis and assembly of viral structural components, genome packaging and maturation into an infectious virion. Each chapter will describe the components of the respective machine in molecular or atomic detail, genetic and biochemical analyses, and mechanism. Topics are carefully selected so that the reader is exposed to systems where there is a substantial infusion of new knowledge in recent years, which greatly elevated the fundamental mechanistic understanding of the respective molecular machine. The authors will be encouraged to simplify the detailed knowledge to basic concepts, include provocative new ideas, as well as design colorful graphics, thus making the cutting-edge information accessible to broad audience.
Author | : Michael G. Rossmann |
Publisher | : Springer |
Total Pages | : 687 |
Release | : 2016-08-23 |
Genre | : Medical |
ISBN | : 9781493950850 |
Download Viral Molecular Machines Book in PDF, ePub and Kindle
This book will contain a series of solicited chapters that concern with the molecular machines required by viruses to perform various essential functions of virus life cycle. The first three chapters (Introduction, Molecular Machines and Virus Architecture) introduce the reader to the best known molecular machines and to the structure of viruses. The remainder of the book will examine in detail various stages of the viral life cycle. Beginning with the viral entry into a host cell, the book takes the reader through replication of the genome, synthesis and assembly of viral structural components, genome packaging and maturation into an infectious virion. Each chapter will describe the components of the respective machine in molecular or atomic detail, genetic and biochemical analyses, and mechanism. Topics are carefully selected so that the reader is exposed to systems where there is a substantial infusion of new knowledge in recent years, which greatly elevated the fundamental mechanistic understanding of the respective molecular machine. The authors will be encouraged to simplify the detailed knowledge to basic concepts, include provocative new ideas, as well as design colorful graphics, thus making the cutting-edge information accessible to broad audience.
Author | : Ron Milo |
Publisher | : Garland Science |
Total Pages | : 400 |
Release | : 2015-12-07 |
Genre | : Science |
ISBN | : 1317230698 |
Download Cell Biology by the Numbers Book in PDF, ePub and Kindle
A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
Author | : David S. Goodsell |
Publisher | : Springer Science & Business Media |
Total Pages | : 174 |
Release | : 2009-04-10 |
Genre | : Science |
ISBN | : 0387849254 |
Download The Machinery of Life Book in PDF, ePub and Kindle
Imagine that we had some way to look directly at the molecules in a living organism. An x-ray microscope would do the trick, or since we’re dreaming, perhaps an Asimov-style nanosubmarine (unfortunately, neither is currently feasible). Think of the wonders we could witness firsthand: antibodies atta- ing a virus, electrical signals racing down nerve fibers, proteins building new strands of DNA. Many of the questions puzzling the current cadre of sci- tists would be answered at a glance. But the nanoscale world of molecules is separated from our everyday world of experience by a daunting million-fold difference in size, so the world of molecules is completely invisible. I created the illustrations in this book to help bridge this gulf and allow us to see the molecular structure of cells, if not directly, then in an artistic rendition. I have included two types of illustrations with this goal in mind: watercolor paintings which magnify a small portion of a living cell by one million times, showing the arrangement of molecules inside, and comput- generated pictures, which show the atomic details of individual molecules. In this second edition of The Machinery of Life, these illustrations are presented in full color, and they incorporate many of the exciting scientific advances of the 15 years since the first edition.
Author | : Mauricio G. Mateu |
Publisher | : Springer Science & Business Media |
Total Pages | : 734 |
Release | : 2013-06-04 |
Genre | : Medical |
ISBN | : 9400765525 |
Download Structure and Physics of Viruses Book in PDF, ePub and Kindle
This book contemplates the structure, dynamics and physics of virus particles: From the moment they come into existence by self-assembly from viral components produced in the infected cell, through their extracellular stage, until they recognise and infect a new host cell and cease to exist by losing their physical integrity to start a new infectious cycle. (Bio)physical techniques used to study the structure of virus particles and components, and some applications of structure-based studies of viruses are also contemplated. This book is aimed first at M.Sc. students, Ph.D. students and postdoctoral researchers with a university degree in biology, chemistry, physics or related scientific disciplines who share an interest or are actually working on viruses. We have aimed also at providing an updated account of many important concepts, techniques, studies and applications in structural and physical virology for established scientists working on viruses, irrespective of their physical, chemical or biological background and their field of expertise. We have not attempted to provide a collection of for-experts-only reviews focused mainly on the latest research in specific topics; we have not generally assumed that the reader knows all of the jargon and all but the most recent and advanced results in each topic dealt with in this book. In short, we have attempted to write a book basic enough to be useful to M.Sc and Ph.D. students, as well as advanced and current enough to be useful to senior scientists with an interest in Structural and/or Physical Virology.
Author | : Wang-Shick Ryu |
Publisher | : Academic Press |
Total Pages | : 440 |
Release | : 2016-03-30 |
Genre | : Science |
ISBN | : 0128009993 |
Download Molecular Virology of Human Pathogenic Viruses Book in PDF, ePub and Kindle
Molecular Virology of Human Pathogenic Viruses presents robust coverage of the key principles of molecular virology while emphasizing virus family structure and providing key context points for topical advances in the field. The book is organized in a logical manner to aid in student discoverability and comprehension and is based on the author’s more than 20 years of teaching experience. Each chapter will describe the viral life cycle covering the order of classification, virion and genome structure, viral proteins, life cycle, and the effect on host and an emphasis on virus-host interaction is conveyed throughout the text. Molecular Virology of Human Pathogenic Viruses provides essential information for students and professionals in virology, molecular biology, microbiology, infectious disease, and immunology and contains outstanding features such as study questions and recommended journal articles with perspectives at the end of each chapter to assist students with scientific inquiries and in reading primary literature. Presents viruses within their family structure Contains recommended journal articles with perspectives to put primary literature in context Includes integrated recommended reading references within each chapter Provides access to online ancillary package inclusive of annotated PowerPoint images, instructor’s manual, study guide, and test bank
Author | : Eric Drexler |
Publisher | : Anchor |
Total Pages | : 314 |
Release | : 1987-09-16 |
Genre | : Science |
ISBN | : 0385199732 |
Download Engines of Creation Book in PDF, ePub and Kindle
This brilliant work heralds the new age of nanotechnology, which will give us thorough and inexpensive control of the structure of matter. Drexler examines the enormous implications of these developments for medicine, the economy, and the environment, and makes astounding yet well-founded projections for the future.
Author | : M. A. Epstein |
Publisher | : Springer Science & Business Media |
Total Pages | : 467 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 3642672361 |
Download The Epstein-Barr Virus Book in PDF, ePub and Kindle
The Epstein-Barr virus was discovered 15 years ago. Since that time an immense body of information has been accumu lated on this agent which has come to assume great signifi cance in many different fields of biological science. Thus, the virus has very special relevance in human medicine and oncology, in tumor virology, in immunology, and in mole cular virology, since it is the cause of infectious mononu cleosis and also the first human cancer virus, etiologically related to endemic Burkitt's lymphoma and probably to nasopharyngeal carcinoma. In addition, continuous human lymphoid cell lines initiated and maintained by the transform ing function of the virus genome provide a laboratory tool with wide and ever-growing applications. Innumerable papers on the Epstein-Barr virus have ap peared over recent years and reports of work with this agent now constitute a veritable flood. The present book provides the first and only comprehensive, authoritative over-view of all aspects of the virus by authors who have been the original and major contributors in their particular disciplines. A complete and up-to-date survey of this unique and important agent is thus provided which should be of great interest to experts, teachers, and students engaged in cancer research, virology, immunology, molecular biology, epide miology, and cell culture. Where topics have been dealt with from more than one of these viewpoints, some inevitable overlap and duplication has resulted; although this has been kept to a minimum, it has been retained in some places because of positive usefulness.
Author | : A. L. Notkins |
Publisher | : Springer Science & Business Media |
Total Pages | : 418 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 1461252504 |
Download Concepts in Viral Pathogenesis Book in PDF, ePub and Kindle
The current proliferation of scientific information makes it difficult for even the most diligent reader to keep up with the latest developments in his/her own field, let alone other areas of interest. Review articles are one solution, but they too have become so voluminous and detailed that they often defeat the purpose for which they were intended. We have attempted to ease this problem by using a different format. In this volume on Concepts in Viral Pathogenesis, we have assembled a series of mini-reviews/editorials, 1,000 to 2,000 words in length. Each is a pithy distil lation of the state-of-the-art with emphasis on current thinking and unifying concepts rather than a compendium of the literature. The 53 articles, all written by active workers in their respective fields, are organized systemati cally so that the book will provide busy investigators, teachers and students of up-to-date information in a very brief and easily read a conceptual core able form. In addition, the authors have attempted to identify unresolved problems and point to future directions.
Author | : O.-R. Kaaden |
Publisher | : Springer Science & Business Media |
Total Pages | : 307 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 3709193001 |
Download Unconventional Agents and Unclassified Viruses Book in PDF, ePub and Kindle
Among unconventional agents and unclassified viruses the contributions to this volume focused on prion-related diseases, with special emphasis on bovine spongiform encephalopathy and human spongiform encephalopathies, and Borna disease virus, an agent known since long time to be pathogenic for horses and sheep, which is now discussed as a potential pathogen for humans. Additionally, the volume contains articles about newly discovered viruses like porcine respiratory and reproductive syndrome virus and viruses that are classified only provisionally like African swine fever virus, hepatitis C and E viruses, or the arteriviruses.