Viral Fitness And Evolution PDF Download
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Author | : Esteban Domingo |
Publisher | : Elsevier |
Total Pages | : 573 |
Release | : 2008-06-23 |
Genre | : Science |
ISBN | : 0080564968 |
Download Origin and Evolution of Viruses Book in PDF, ePub and Kindle
New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases. NEW - methods to establish relationships among viruses and the mechanisms that affect virus evolution UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups SPECIFIC - Bacterial, plant, animal and human viruses are compared regarding their interation with their hosts
Author | : Esteban Domingo |
Publisher | : Springer Nature |
Total Pages | : 350 |
Release | : 2023-01-02 |
Genre | : Medical |
ISBN | : 3031156404 |
Download Viral Fitness and Evolution Book in PDF, ePub and Kindle
This book unifies general concepts of plant and animal virus evolution and covers a broad range of topics related to theoretical and experimental aspects of virus population dynamics and viral fitness. Timely topics such as viral mechanisms to cope with antiviral agents, the adaptability of the virus to new hosts, emergence of new viral phenotypes, and the connections between short- and long-term virus evolution are included. By comparing plant and animal viruses, universal mechanisms responsible for fitness variations, viral emergence and disease mechanisms are explored. Although emphasis is put on specific plant and human viral pathogens, relevant similarities and differences to other viruses are highlighted. Additionally, readers will learn more about the adaptability of coronaviruses, including the recently emerged SARS-CoV-2, the causative agent of the COVID-19 pandemic. The book is aimed at students and scientists interested in basic and applied aspects of plant and animal virus population dynamics and evolution.
Author | : Edward C. Holmes |
Publisher | : Oxford University Press |
Total Pages | : 267 |
Release | : 2009-06-25 |
Genre | : Language Arts & Disciplines |
ISBN | : 0199211124 |
Download The Evolution and Emergence of RNA Viruses Book in PDF, ePub and Kindle
While the study of viral evolution has developed rapidly in the last 30 years, little attention has been directed toward linking the mechanisms of viral evolution to the epidemiological outcomes of these processes. This book intends to fill this gap by considering the patterns and processes of viral evolution at all its spatial and temporal scales.
Author | : Esteban Domingo |
Publisher | : Academic Press |
Total Pages | : 426 |
Release | : 2019-11-06 |
Genre | : Science |
ISBN | : 0128163321 |
Download Virus as Populations Book in PDF, ePub and Kindle
Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. Features current views on key steps in the origin of life and origins of viruses Includes examples relating ancestral features of viruses with their current adaptive capacity Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read Considers quasispecies as a framework to understand virus adaptability and disease processes
Author | : Igor M. Rouzine |
Publisher | : Walter de Gruyter GmbH & Co KG |
Total Pages | : 322 |
Release | : 2023-09-18 |
Genre | : Mathematics |
ISBN | : 3110697386 |
Download Fitness Landscape, Red Queen, Evolutionary Enigmas, and Applications to Virology Book in PDF, ePub and Kindle
Author | : Jaap Goudsmit |
Publisher | : Oxford University Press on Demand |
Total Pages | : 204 |
Release | : 2004-08-12 |
Genre | : Medical |
ISBN | : 0195130340 |
Download Viral Fitness Book in PDF, ePub and Kindle
Addressing viral adaption as a general phenomenon, the author examines the heart of viral emergence as human behaviour alters viral ecosystems.
Author | : Marilyn J. Roossinck |
Publisher | : Springer Science & Business Media |
Total Pages | : 227 |
Release | : 2008-02-23 |
Genre | : Science |
ISBN | : 3540757635 |
Download Plant Virus Evolution Book in PDF, ePub and Kindle
This book provides a comprehensive look at the field of plant virus evolution. It is the first book ever published on the topic. Individual chapters, written by experts in the field, cover plant virus ecology, emerging viruses, plant viruses that integrate into the host genome, population biology, evolutionary mechanisms and appropriate methods for analysis. It covers RNA viruses, DNA viruses, pararetroviruses and viroids, and presents a number of thought-provoking ideas.
Author | : Richard E. Michod |
Publisher | : Princeton University Press |
Total Pages | : 282 |
Release | : 2021-01-12 |
Genre | : Science |
ISBN | : 0691223866 |
Download Darwinian Dynamics Book in PDF, ePub and Kindle
The concept of fitness has long been a topic of intense debate among evolutionary biologists and their critics, with its definition and explanatory power coming under attack. In this book, Richard Michod offers a fresh, dynamical interpretation of evolution and fitness concepts. He argues that evolution has no enduring products; what matters is the process of genetic change. Whereas many biologists have focused on competition and aggression as determining factors in survival, Michod, by concentrating on the emergence of individuality at new and more complex levels, finds that cooperation plays even a greater role. Michod first considers the principles behind the hierarchically nested levels of organization that constitute life: genes, chromosomes, genomes, cells, multicellular organisms, and societies. By examining the evolutionary transitions from the molecular level up to the whole organism, the author explains how cooperation and conflict in a multilevel setting leads to new levels of fitness. He builds a model of fitness drawing on recent developments in ecology and multilevel selection theory and on new explanations of the origin of life. Michod concludes with a discussion of the philosophical implications of his theory of fitness, a theory that addresses the most fundamental and unique concept in all of biology.
Author | : Maria Anisimova |
Publisher | : |
Total Pages | : |
Release | : 2012 |
Genre | : Evolutionary genetics |
ISBN | : 9781617795824 |
Download Evolutionary Genomics Book in PDF, ePub and Kindle
Author | : Christon J. Hurst |
Publisher | : John Wiley & Sons |
Total Pages | : 389 |
Release | : 2011-06-20 |
Genre | : Science |
ISBN | : 1118025652 |
Download Studies in Viral Ecology, Volume 1 Book in PDF, ePub and Kindle
This book explains the ecology of viruses by examining their interactive dynamics with their hosting species (in this volume, in microbes and plants), including the types of transmission cycles that viruses have evolved encompassing principal and alternate hosts, vehicles, and vectoring species. Examining virology from an organismal biology approach and focusing on the concept that viral infections represent areas of overlap in the ecologies of the involved species, Viral Ecology is essential for students and professionals who either may be non-virologists or virologists whose previous familiarity has been very specialized.