Vertebrate Limb Myogenesis PDF Download
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Author | : Beate Brand-Saberi |
Publisher | : Springer Science & Business Media |
Total Pages | : 250 |
Release | : 2012-11-03 |
Genre | : Science |
ISBN | : 3540456864 |
Download Vertebrate Myogenesis Book in PDF, ePub and Kindle
The development of vertebrate muscle has long been a major area of research in developmental biology. During the last decade, novel technical approaches have allowed us to unravel to a large extent the mechanisms underlying muscle formation, and myogenesis has become one of the best-understood paradigms for cellular differentiation. This book concisely summarizes our current knowledge about muscle development in vertebrates, from the determination of muscle precursors to terminal differentiation. Each chapter has been written by an expert in the field, and particular emphasis has been placed on the different developmental and molecular pathways followed by the three types of vertebrate musculature - skeletal, heart and smooth muscle.
Author | : Beate Brand-Saberi |
Publisher | : Springer |
Total Pages | : 245 |
Release | : 2014-10-25 |
Genre | : Science |
ISBN | : 3662446081 |
Download Vertebrate Myogenesis Book in PDF, ePub and Kindle
This book addresses the differentiation control of skeletal muscle in different locations of the vertebrate body Particular attention is paid to novel regulatory molecules and signals as well as the heterogeneity of origin that have revealed a developmental overlap between skeletal and cardiac muscle. Different functional muscle groups are the product of the evolution of the vertebrate classes, making a phylogenetic comparison worthwhile for understanding the role of muscle stem cells and precursors in myogenesis. New insights into the hierarchy of transcription factors, particularly in the context of these different muscle groups have been gained from detailed investigations of the spatio-temporal and regulatory relationships derived from mouse and zebrafish genetics and avian microsurgery. Importantly, epigenetic mechanisms that have surfaced recently, in particular the role of MyomiRs, are also surveyed. With an eye to the human patient, encouraging results have been generated that identify parallels between embryonic myogenesis and regenerating myofibers due to common regulatory molecules. On the other hand, both processes differ considerably in quality and complexity of the processes employed. Interestingly, the heterogeneity in embryonic sources from which skeletal muscle groups in the vertebrate including the human body take origin is paralleled by differences in their susceptibility to particular muscle dystrophies as well as by the characteristics of the satellite cells involved in regeneration. The progress that has been made in the field of muscle stem cell biology, with special focus on the satellite cells, is outlined in this book by experts in the field. The authors review recent insights of the heterogeneous nature of these satellite cells regarding their gene signatures and regeneration potential. Furthermore, an improved understanding of muscle stem cells seems only possible when we study the impact of the cell environment on efficient stem cell replacement therapies for muscular dystrophies, putting embryological findings from different vertebrate classes and stem cell approaches into context.
Author | : Antonio Seung Jin Lee |
Publisher | : |
Total Pages | : 532 |
Release | : 2006 |
Genre | : Extremities (Anatomy) |
ISBN | : |
Download Myogenic Mononucleated Cell Populations in the Developing Vertebrate Limb in Vivo Book in PDF, ePub and Kindle
In summary, this study provides quantitative data to demonstrate dynamic changes in various mononucleated myogenic cell populations during skeletal muscle formation and reveals that Pax7(+ve) population becomes significantly upregulated during secondary myogenesis.
Author | : Helen Sink |
Publisher | : Springer Science & Business Media |
Total Pages | : 224 |
Release | : 2006-02-02 |
Genre | : Science |
ISBN | : 9780387300535 |
Download Muscle Development in Drosophilia Book in PDF, ePub and Kindle
The different aspects of muscle development are considered from cellular, molecular and genetic viewpoints, and the text is supported by black/white and color illustrations. The book will appeal to those studying muscle development and muscle biology in any organism.
Author | : Jennifer Gail Seed |
Publisher | : |
Total Pages | : 220 |
Release | : 1987 |
Genre | : Cell lines |
ISBN | : |
Download Vertebrate Limb Myogenesis Book in PDF, ePub and Kindle
Author | : Gi Fay Mok |
Publisher | : |
Total Pages | : |
Release | : 2014 |
Genre | : |
ISBN | : |
Download Characterisation of the MRFs and Role of FGF18 in Vertebrate Limb Myogenesis Book in PDF, ePub and Kindle
Author | : J.Richard Hinchliffe |
Publisher | : Springer Science & Business Media |
Total Pages | : 434 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 1461533104 |
Download Developmental Patterning of the Vertebrate Limb Book in PDF, ePub and Kindle
Following pioneering work by Harrison on amphibian limbs in the 1920s and by Saunders (1948) on the apical ridge in chick limbs, limb development became a classical model system for investigating such fundamental developmental issues as tissue interactions and induction, and the control of pattern formation. Earlier international conferences, at Grenoble 1972, Glasgow 1976,and Storrs, Connecticut 1982, reflected the interests and technology of their time. Grenoble was concerned with ectoderm-mesenchyme interaction, but by the time of the Glasgow meeting, the zone of polarizing activity (ZPA) and its role in control of patterning was the dominant theme. Storrs produced the first intimations that the ZPA could be mimicked by retinoic acid (RA), but the diversity of extracellular masrix ~olecules,particularly in skeletogenesis,was the main focus of attention. By 1990, the paradigms had again shifted. Originally, the planners of the ARW saw retinoic acid (as a possible morphogen controlling skeletal patterning), the variety of extracellular matrix components and their roles, and the developmental basis of limb evolution as the leading contemporary topics. However, as planning proceeded, it was clear that the new results emerging from the use of homeobox gene probes (first developed to investigate the genetic control of patterning of Drosophila embryos) to analyse the localised expression of "patterning genes" in limb buds would also be an important theme.
Author | : D.A. Sassoon |
Publisher | : Elsevier |
Total Pages | : 153 |
Release | : 2002-02-08 |
Genre | : Science |
ISBN | : 0080569730 |
Download Stem Cells and Cell Signalling in Skeletal Myogenesis Book in PDF, ePub and Kindle
Skeletal muscle development is perhaps one of the best understood processes at the molecular, cellular and organismal level due in large part to the fact that primary myogenic cells (myoblasts) will grow and subsequently differentiate into myotubes in culture. With the advent of reverse mouse genetics, many of the observations gained through the study of myogenic cells in vitro have been directly tested in vivo. What has emerged is a complex but cohesive story of how myogenic cells are initially specified in the vertebrate embryo and how muscle fibers ultimately achieve their respective identities (i.e. fast versus slow) to perform their function. This collection of chapters is focused on these developments. The book discusses old and new directions for the skeletal muscle field and points out directions where the field may eventually progress.
Author | : Brenda Mary Murray |
Publisher | : |
Total Pages | : |
Release | : 1995 |
Genre | : |
ISBN | : |
Download Factors Regulating Angiogenesis During Myogenesis in the Developing Vertebrate Limb Book in PDF, ePub and Kindle
Author | : George Karpati |
Publisher | : Cambridge University Press |
Total Pages | : 800 |
Release | : 2001-07-12 |
Genre | : Medical |
ISBN | : 9780521650625 |
Download Disorders of Voluntary Muscle Book in PDF, ePub and Kindle
Rewritten and redesigned, this remains the one essential text on the diseases of skeletal muscle.