Vertebrate Hair Cells PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Vertebrate Hair Cells PDF full book. Access full book title Vertebrate Hair Cells.
Author | : Ruth Eatock |
Publisher | : Springer Science & Business Media |
Total Pages | : 465 |
Release | : 2006-07-01 |
Genre | : Science |
ISBN | : 0387317066 |
Download Vertebrate Hair Cells Book in PDF, ePub and Kindle
The Springer Handbook of Auditory Research presents a series of compreh- sive and synthetic reviews of the fundamental topics in modern auditory - search. The volumes are aimed at all individuals with interests in hearing research including advanced graduate students, postdoctoral researchers, and clinical investigators. The volumes are intended to introduce new investigators to important aspects of hearing science and to help established investigators to better understand the fundamental theories and data in ?elds of hearing that they may not normally follow closely. Each volume presents a particular topic comprehensively, and each serves as a synthetic overview and guide to the literature. As such, the chapters present neither exhaustive data reviews nor original research that has not yet appeared in peer-reviewed journals. The volumes focus on topics that have developed a solid data and conceptual foundation rather than on those for which a literature is only beginning to develop. New research areas will be covered on a timely basis in the series as they begin to mature.
Author | : Geoffrey A. Manley |
Publisher | : Springer Science & Business Media |
Total Pages | : 433 |
Release | : 2013-12-01 |
Genre | : Science |
ISBN | : 1441989579 |
Download Evolution of the Vertebrate Auditory System Book in PDF, ePub and Kindle
The function of vertebrate hearing is served by a surprising variety of sensory structures in the different groups of fish, amphibians, reptiles, birds, and mammals. This book discusses the origin, specialization, and functional properties of sensory hair cells, beginning with environmental constraints on acoustic systems and addressing in detail the evolutionary history behind modern structure and function in the vertebrate ear. Taking a comparative approach, chapters are devoted to each of the vertebrate groups, outlining the transition to land existence and the further parallel and independent adaptations of amniotic groups living in air. The volume explores in depth the specific properties of hair cells that allowed them to become sensitive to sound and capable of analyzing sounds into their respective frequency components. Evolution of the Vertebrate Auditory System is directed to a broad audience of biologists and clinicians, from the level of advanced undergraduate students to professionals interested in learning more about the evolution, structure, and function of the ear.
Author | : Ruth Eatock |
Publisher | : Springer |
Total Pages | : 0 |
Release | : 2008-11-01 |
Genre | : Science |
ISBN | : 9780387521961 |
Download Vertebrate Hair Cells Book in PDF, ePub and Kindle
The Springer Handbook of Auditory Research presents a series of compreh- sive and synthetic reviews of the fundamental topics in modern auditory - search. The volumes are aimed at all individuals with interests in hearing research including advanced graduate students, postdoctoral researchers, and clinical investigators. The volumes are intended to introduce new investigators to important aspects of hearing science and to help established investigators to better understand the fundamental theories and data in ?elds of hearing that they may not normally follow closely. Each volume presents a particular topic comprehensively, and each serves as a synthetic overview and guide to the literature. As such, the chapters present neither exhaustive data reviews nor original research that has not yet appeared in peer-reviewed journals. The volumes focus on topics that have developed a solid data and conceptual foundation rather than on those for which a literature is only beginning to develop. New research areas will be covered on a timely basis in the series as they begin to mature.
Author | : Pamela J. Lanford |
Publisher | : |
Total Pages | : 238 |
Release | : 1997 |
Genre | : Hair cells |
ISBN | : |
Download Differentiation of Sensory Hair Cells in the Vertebrate Inner Ear Book in PDF, ePub and Kindle
Author | : Edwin R. Lewis |
Publisher | : Springer |
Total Pages | : 264 |
Release | : 1985-11-11 |
Genre | : Medical |
ISBN | : |
Download VERTEBRATE INNER EAR Book in PDF, ePub and Kindle
Author | : John Abraham Assad |
Publisher | : |
Total Pages | : 298 |
Release | : 1991 |
Genre | : Senses and sensation |
ISBN | : |
Download Sensory Adaptation in Vertebrate Hair Cells Book in PDF, ePub and Kindle
Author | : Paul D. Niksch |
Publisher | : |
Total Pages | : 158 |
Release | : 2012 |
Genre | : |
ISBN | : |
Download A Computational Approach for Understanding Adaptation in Vertebrate Hair Cells Book in PDF, ePub and Kindle
Vertebrate hair cells respond to mechanical stimuli with an inward current that is carried by extracellular cations through mechanically-gated transmembrane ion channels called transduction channels, located in the hair cell's specialized apical surface called the stereocilia. The current is characterized as having a rapid onset and adapting exponentially with a fast and slow time constant. The fast component is usually attributed to calcium binding directly to the transduction channels to promote channel reclosure. Myosin-1C, an unconventional myosin motor protein that is also modulated by calcium, adjusts the tension applied to the transduction channel to cause slow adaptation. Neither adaptation typically acts completely to restore the transduction current back to the baseline level. Recent evidence has suggested that the transduction channel is further away from myosin-IC than previously believed, creating a spatial separation that changes the nature of the calcium feedback. I developed a computational model to explore the motion of vertebrate hair cells simultaneously with calcium diffusion within the cell. The model is also capable of simulating many other experimental techniques that are commonly applied to hair cells. The results of the model suggest a fundamentally different viewpoint for understanding adaptation in vertebrate hair cells. Calcium can create unique responses from different transduction channels within the same hair cell. The implications of these findings help to explain the incompleteness of adaptation as well as implicate myosin-1C for fast adaptation as well as slow adaptation. In addition, groundwork for better understanding stereocilia-based amplification in the mammalian cochlea was developed. Experimental predictions were created to test these theories.
Author | : Michael E. Smith |
Publisher | : Frontiers Media SA |
Total Pages | : 268 |
Release | : 2016-12-13 |
Genre | : Neurosciences. Biological psychiatry. Neuropsychiatry |
ISBN | : 2889450007 |
Download Sensory Hair Cell Death and Regeneration Book in PDF, ePub and Kindle
Sensory hair cells are the specialized mechanosensory receptors found in vertebrate auditory, vestibular, and lateral line organs that transduce vibratory and acoustic stimuli into the sensations of hearing and balance. Hair cells can be damaged due to such factors as aging, ototoxic chemicals, acoustic trauma, infection, or genetic factors. Loss of these hair cells lead to deficits in hearing and balance, and in mammals, such deficits are permanent. In contrast, non-mammalian vertebrates exhibit the capability to regenerate missing hair cells. Researchers have been examining the process of hair cell death and regeneration in animal models in an attempt to find ways of either preventing hair cell loss or stimulating the production of new hair cells in mammals, with the ultimate goal of finding new therapeutics for human sensorineural hearing and balance deficits. This has led to a wide array of research on sensory hair cells- such as understanding the factors that cause hair cell loss and finding agents that protect them from damage, elucidating the cell signaling pathways activated during hair cell death, examining the genes and cellular pathways that are regulated during the process of hair cell death and regeneration, and characterizing the functional sensory loss and recovery following acoustic or ototoxic insults to the inner ear. This research has involved cell and developmental biologists, physiologists, geneticists, bioinformaticians, and otolaryngologists. In this Research Topic, we have collated reviews of the past progress of hair cell death and regeneration studies and original research articles advancing sensory hair cell death and regeneration research into the future.
Author | : David Paul Corey |
Publisher | : |
Total Pages | : 338 |
Release | : 1980 |
Genre | : |
ISBN | : |
Download A Biophysical Approach to Sensory Transduction by Vertebrate Hair Cells Book in PDF, ePub and Kindle
Author | : Wei Xiong |
Publisher | : Springer |
Total Pages | : 60 |
Release | : 2018-04-27 |
Genre | : Medical |
ISBN | : 9811085579 |
Download Mechanotransduction of the Hair Cell Book in PDF, ePub and Kindle
This book summarizes the emerging experimental evidence on hair-cell mechanotransduction, and covers hair’s cellular structure, biophysical properties, molecular components and functions. Auditory hair cells convert sound-induced vibration into electrical signals. This biological process, mechanotransduction, is what allows us to hear and communicate in our daily lives. However, our grasp of hair-cell mechanotransduction is still far from complete. Recent advances in molecular genetics and biophysics have helped us gain deeper insights into this process, especially the molecular constituent and operation of the channel complex. This book provides a cutting-edge snapshot for all readers who are interested in or studying how auditory hair cells detect sound.