Validation and Refinement of Genetic Networks in Yeast
Author | : Trey Ideker |
Publisher | : |
Total Pages | : 156 |
Release | : 2001 |
Genre | : |
ISBN | : |
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Author | : Trey Ideker |
Publisher | : |
Total Pages | : 156 |
Release | : 2001 |
Genre | : |
ISBN | : |
Author | : |
Publisher | : |
Total Pages | : 776 |
Release | : 2001 |
Genre | : Dissertation abstracts |
ISBN | : |
Author | : Niloy Ganguly |
Publisher | : Springer Science & Business Media |
Total Pages | : 310 |
Release | : 2009-04-14 |
Genre | : Computers |
ISBN | : 0817647503 |
This self-contained book systematically explores the statistical dynamics on and of complex networks having relevance across a large number of scientific disciplines. The theories related to complex networks are increasingly being used by researchers for their usefulness in harnessing the most difficult problems of a particular discipline. The book is a collection of surveys and cutting-edge research contributions exploring the interdisciplinary relationship of dynamics on and of complex networks. Topics covered include complex networks found in nature—genetic pathways, ecological networks, linguistic systems, and social systems—as well as man-made systems such as the World Wide Web and peer-to-peer networks. The contributed chapters in this volume are intended to promote cross-fertilization in several research areas, and will be valuable to newcomers in the field, experienced researchers, practitioners, and graduate students interested in systems exhibiting an underlying complex network structure in disciplines such as computer science, biology, statistical physics, nonlinear dynamics, linguistics, and the social sciences.
Author | : Peter Markstein |
Publisher | : Imperial College Press |
Total Pages | : 420 |
Release | : 2006 |
Genre | : Science |
ISBN | : 186094700X |
This volume contains about 40 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications. There are also abstracts from the keynote addresses and invited talks.The papers cover not only theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field.
Author | : Peter Markstein |
Publisher | : World Scientific |
Total Pages | : 418 |
Release | : 2006-07-28 |
Genre | : Science |
ISBN | : 190897947X |
This volume contains about 40 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications. There are also abstracts from the keynote addresses and invited talks.The papers cover not only theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field./a
Author | : Florian Markowetz |
Publisher | : Cambridge University Press |
Total Pages | : 287 |
Release | : 2015-07-02 |
Genre | : Science |
ISBN | : 131638098X |
Whereas genetic studies have traditionally focused on explaining heritance of single traits and their phenotypes, recent technological advances have made it possible to comprehensively dissect the genetic architecture of complex traits and quantify how genes interact to shape phenotypes. This exciting new area has been termed systems genetics and is born out of a synthesis of multiple fields, integrating a range of approaches and exploiting our increased ability to obtain quantitative and detailed measurements on a broad spectrum of phenotypes. Gathering the contributions of leading scientists, both computational and experimental, this book shows how experimental perturbations can help us to understand the link between genotype and phenotype. A snapshot of current research activity and state-of-the-art approaches to systems genetics are provided, including work from model organisms such as Saccharomyces cerevisiae and Drosophila melanogaster, as well as from human studies.
Author | : |
Publisher | : |
Total Pages | : 850 |
Release | : 2008 |
Genre | : Dissertations, Academic |
ISBN | : |
Author | : Robert King |
Publisher | : Springer Science & Business Media |
Total Pages | : 662 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 1461571480 |
Many modern geneticists attempt to elucidate the molecular basis of phenotype by utilizing a battery of techniques derived from physical chemistry on subcellular components isolated from various species of organisms. Volume 5 of the Handbook of Genetics provides explanations of the advantages and shortcomings of some of these revolutionary tech niques, and the nonspecialist is alerted to key research papers, reviews, and reference works. Much of the text deals with the structure and func tioning of the molecules bearing genetic information which reside in the nucleus and with the processing of this information by the ribosomes resid ing in the cytoplasm of eukaryotic cells. The mitochondria, which also live in the cytoplasm of the cells of all eukaryotes, now appear to be separate little creatures. These, as Lynn Margulis pointed out in Volume 1, are the colonial posterity of migrant prokaryotes, probably primitive bacteria that swam into the ancestral precursors of all eukaryotic cells and remained as symbionts. They have maintained themselves and their ways ever since, replicating their own DNA and transcribing an RNA quite different from that of their hosts. In a similar manner, the chloroplasts in all plants are self-replicating organelles presumably derived from the blue-green algae, with their own nucleic acids and ribosomes. Four chapters are devoted to the nucleic acids and the ribosomal components of both classes of these semi-independent lodgers. Finally, data from various sources on genetic variants of enzymes are tabulated for ready reference, and an evaluation of this information is attempted.
Author | : Sacha Baginsky |
Publisher | : Springer Science & Business Media |
Total Pages | : 362 |
Release | : 2007-06-25 |
Genre | : Science |
ISBN | : 376437439X |
This volume aims to provide a timely view of the state-of-the-art in systems biology. The editors take the opportunity to define systems biology as they and the contributing authors see it, and this will lay the groundwork for future studies. The volume is well-suited to both students and researchers interested in the methods of systems biology. Although the focus is on plant systems biology, the proposed material could be suitably applied to any organism.
Author | : Fabricio Alves Barbosa da Silva |
Publisher | : Springer Nature |
Total Pages | : 381 |
Release | : 2020-10-03 |
Genre | : Computers |
ISBN | : 3030518620 |
This book presents a range of current research topics in biological network modeling, as well as its application in studies on human hosts, pathogens, and diseases. Systems biology is a rapidly expanding field that involves the study of biological systems through the mathematical modeling and analysis of large volumes of biological data. Gathering contributions from renowned experts in the field, some of the topics discussed in depth here include networks in systems biology, the computational modeling of multidrug-resistant bacteria, and systems biology of cancer. Given its scope, the book is intended for researchers, advanced students, and practitioners of systems biology. The chapters are research-oriented, and present some of the latest findings on their respective topics.