Using Animal Models In Biomedical Research A Primer For The Investigator PDF Download
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| Author | : Pierce K H Chow |
| Publisher | : World Scientific |
| Total Pages | : 309 |
| Release | : 2008-01-02 |
| Genre | : Medical |
| ISBN | : 9814365416 |
Download Using Animal Models In Biomedical Research: A Primer For The Investigator Book in PDF, ePub and Kindle
Animal models play crucial roles in the continuum of experimental activities that make up biomedical research. Such in vivo modes are especially important in proof-of-principle experiments and in establishing the preclinical safety and efficacy data required for progressing to human clinical trials. A practical understanding of the choice, care and use of animal models is thus expected and required of all biomedical researchers. However, while both legislations and the practice of laboratory animal science have made great advances in the last decade and have impacted significantly on the use of animal models, this corpus of knowledge is not readily available in formats easily digestible to the average biomedical researcher. This book fills this gap in knowledge and provides material not easily sourced by the average biomedical researcher, such as current information on bioimaging, occupational health and biosafety, animal protocol design and histological-pathological support.
| Author | : Foundation for Biomedical Research (Washington, D.C.) |
| Publisher | : |
| Total Pages | : 102 |
| Release | : 1987 |
| Genre | : Animal experimentation |
| ISBN | : |
Download The Biomedical Investigator's Handbook Book in PDF, ePub and Kindle
| Author | : Pierce K. H. Chow |
| Publisher | : World Scientific |
| Total Pages | : 309 |
| Release | : 2008 |
| Genre | : Medical |
| ISBN | : 9812812024 |
Download Using Animal Models in Biomedical Research Book in PDF, ePub and Kindle
Ch. 1. Scientific considerations and choice of species. ch. 1.1. The rationale for the use of animal models in biomedical research / Pierce Chow. ch. 1.2. Experimental animal models in biomedical resarch / Robert Ng. ch. 1.3. Nonhuman primates as models in biomedical research / Jason Vilano and Bryan Ogden -- ch. 2. Regulatory considerations in the use of animal models. ch. 2.1. Laws, regulations and guidelines for biomedical research in Singapore / Boon Theng Kuah. ch. 2.2. The functions of the institutional animal care and use committee / Pierce Chow. ch. 2.3. Responsibilities of principal investigators and research protocol evaluation / Hock Soo Ong. ch. 2.4. The 3R's, research variables and the use of alternatives / Hock Soo Ong. ch. 2.5. Use of statistics as determinant for number of animals used / Huihua Li. ch. 2.6. The advantages of accreditation with AAALAC / Bryan Ogden -- ch. 3. Animal handling and surgical procedures. ch. 3.1. General handling, restraint, oral dosing/gavage and injections in laboratory animals / Bryan Ogden. ch. 3.2. Blood collection from laboratory animals / Jason Villano. ch. 3.3. Antibiotic coverage and therapy / Darvi Sergio. ch. 3.4. Animal preparation and transport / Robert Ng. ch. 3.5. Preparation and implementation of animal surgery / Robert Ng. ch. 3.6. Animal intubation / Robert Ng. ch. 3.7. Anaesthesia and maintenance of homeostasis / Robert Ng. ch. 3.8. Animal euthanasia / Darvi Sergio. ch. 3.9. Rodent sentinel programme / Peik Khin Tan -- ch. 4. Basic animal investigative methods. ch. 4.1. Bioimaging in animals / David Ng [und weitere]. ch. 4.2. Histology sampling and techniques / In Chin Song. ch. 4.3. Animal tissue perfusion and preservation / Robert Ng. ch. 4.4. Animal cell culture / Kai Zhang and Peggy Yong. ch. 4.5. Application of microsurgical techniques in animal research / Bien Keem Tan [und weitere] -- ch. 5. Animal welfare considerations. ch. 5.1. Species specific caging configuration and design / Cindy Phua. ch. 5.2. Postoperative care and pain management / Jason Villano. ch. 5.3. Animal feeds and nutritional requirements / Peik Khin Tan -- ch. 6. Safety management of an animal facility. ch. 6.1. Occupational health and safety programme / Angela Goh. ch. 6.2. New employee and external users orientation / Inria Kurniawan Then. ch. 6.3. Radiation safety awareness in animal research / S. Somanesan. ch. 6.4. Emergency crisis management / Irene Kee. ch. 6.5. Zoonoses and laboratory animal allergies / Jason Villano -- ch. 7. Supporting facilities design. ch. 7.1. Clinical skills laboratory / Robert Ng. ch. 7.2. Animal research supporting laboratories / Robert Ng. ch. 7.3. Animal research and housing facilities / Robert Ng -- ch. 8. The development of comprehensive animal facilities in Singapore. ch. 8.1. History of the Department of Experimental Surgery as a reflection of translational research development in Singapore / Robert Ng
| Author | : P. Michael Conn |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 756 |
| Release | : 2008 |
| Genre | : Medical |
| ISBN | : 1588299333 |
Download Sourcebook of Models for Biomedical Research Book in PDF, ePub and Kindle
The collection of systems represented in Sourcebook of genomic programs, although this work is certainly well Models for Biomedical Research is an effort to re?ect the represented and indexed. diversity and utility of models that are used in biomedicine. Some models have been omitted due to page limitations That utility is based on the consideration that observations and we have encouraged the authors to use tables and made in particular organisms will provide insight into the ? gures to make comparisons of models so that observations workings of other, more complex, systems. Even the cell not available in primary publications can become useful to cycle in the simple yeast cell has similarities to that in the reader. humans and regulation with similar proteins occurs. We thank Richard Lansing and the staff at Humana for Some models have the advantage that the reproductive, guidance through the publication process. mitotic, development or aging cycles are rapid compared As this book was entering production, we learned of the with those in humans; others are utilized because individual loss of Tom Lanigan, Sr. Tom was a leader and innovator proteins may be studied in an advantageous way and that in scienti?c publishing and a good friend and colleague to have human homologs. Other organisms are facile to grow all in the exploratory enterprise. We dedicate this book to in laboratory settings or lend themselves to convenient analy- his memory. We will miss him greatly.
| Author | : |
| Publisher | : DIANE Publishing |
| Total Pages | : 92 |
| Release | : 1993-07 |
| Genre | : Animal models in research |
| ISBN | : 9781568069241 |
Download Animal Models in Biomedical Research Book in PDF, ePub and Kindle
| Author | : Cynthia Petrie Smith |
| Publisher | : |
| Total Pages | : 66 |
| Release | : 1991 |
| Genre | : Animal models in research |
| ISBN | : |
Download Animal Models in Biomedical Research Book in PDF, ePub and Kindle
| Author | : |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 1968 |
| Genre | : |
| ISBN | : |
Download Animal Models for Biomedical Research Book in PDF, ePub and Kindle
| Author | : Gabrielle C. Musk |
| Publisher | : MDPI |
| Total Pages | : 234 |
| Release | : 2021-04-06 |
| Genre | : Science |
| ISBN | : 3036503323 |
Download Refinements to Animal Models for Biomedical Research Book in PDF, ePub and Kindle
There is some talk about an antibiotic Armageddon, wherein untreatable post-operative infections and similarly untreatable complications after chemotherapy will occur. The now famous “O’Neill Report” suggests that, by 2050, more people could die from resistant bacterial infections than from cancer. We are still learning about all the subtle drivers of antibiotic resistance, realizing that we need a single “whole health” coordinated policy. We ingest what we sometimes feed to animals, yet there does not seem to be any new classes of antibiotics on the horizon. Maybe there is something that has been around forever that could could to our rescue: bacteriophages. Nevertheless, we have to do things differently. We must use antibiotics appropriately and for the correct indication, duration, and dosage with good practice and stewardship.. While by no means comprehensive, this book covers many topics regarding antibiotic stewardship. It also addresses older antibiotics, new combinations, and even new agents. Last but not least, this book features two excellent articles on bacteriophages. Refinements to animal models used in research for either human or animal benefit must be an ongoing aim for anyone working in this context, whether it be as an animal carrier, an animal user, a veterinarian, or an official. Unfortunately, the details of refinements are often overlooked in publications describing the research outcomes. This book includes manuscripts published in the Animals Special Issue “Refinements to Animal Models for Biomedical Research”. In this contemporary resource, we included 12 peer-reviewed papers that cover a range of approaches to the concept of refinement.
| Author | : Cynthia Petrie Smith |
| Publisher | : |
| Total Pages | : 92 |
| Release | : 1992 |
| Genre | : Animal models in research |
| ISBN | : |
Download Animal Models in Biomedical Research Book in PDF, ePub and Kindle
| Author | : Enqi Liu |
| Publisher | : CRC Press |
| Total Pages | : 352 |
| Release | : 2017-07-28 |
| Genre | : Medical |
| ISBN | : 1498743528 |
Download Fundamentals of Laboratory Animal Science Book in PDF, ePub and Kindle
Laboratory animals are becoming increasingly important for biomedical research. It is said that approximately 70% of biomedical research is associated with the use of experimental animals. Laboratory animal research not only expands our knowledge of science, but also greatly improves human and animal health. The field of laboratory animal science is ever-growing and changing as new experimental techniques are developed and new animal models are created. It is essential to know not only the biological features of each laboratory animal but also how to use and care for them responsibly in order to perform high-quality experiments. Courses in beginning Laboratory Animal Science are starting to be offered in many universities throughout the world. However, a practical introductory textbook that contains state-of-the-art techniques is still lacking. Fundamentals of Laboratory Animal Science provides comprehensive information on the principles and practices of using laboratory animals for biomedical research. Each individual chapter focuses on a key sub-discipline of laboratory animal science: animal welfare and best humane care practices in the laboratory; the quality control of laboratory animals; the anatomy, physiology, and husbandry of commonly used species; the principles of creating and using animal models for studying human diseases; practical techniques used for laboratory animal experiments; experimental design; and animal experimentation management. Knowledge of this broad spectrum of concepts and skills will ensure research goes smoothly while greatly reducing animal pain and distress. Well-illustrated and thoroughly referenced, this book will serve not only as a standard textbook but also as a handy guide for veterinarians, researchers, animal care staff, administrators, and other professionals who are involved in laboratory animal science.
