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| Author | : Antonella Zannetti |
| Publisher | : Frontiers Media SA |
| Total Pages | : 566 |
| Release | : 2021-09-30 |
| Genre | : Medical |
| ISBN | : 2889714489 |
| Author | : Xu Wang |
| Publisher | : Frontiers Media SA |
| Total Pages | : 448 |
| Release | : 2022-03-25 |
| Genre | : Medical |
| ISBN | : 2889747549 |
| Author | : Wen-Sheng Wu |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 293 |
| Release | : 2010-10-04 |
| Genre | : Medical |
| ISBN | : 9048195225 |
This book examines the signal mechanisms responsible for triggering a series of phenotypical changes of primary tumor which may lead to final colonization of the tumor in a second home. It highlights the initial stage of tumor metastasis.
| Author | : Alessandro Fatatis |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 373 |
| Release | : 2012-01-03 |
| Genre | : Medical |
| ISBN | : 9400725574 |
This work presents the most advanced discoveries from translational research laboratories directly involved in identifying molecules and signalling pathways that play an instrumental role in metastasis. In contrast to other works, conventionally focused on a single type of tumour, the various chapters in this book provide a broad perspective of the similarities and discrepancies among the dissemination of several solid malignancies. Through recurrent and overlapping references to molecular mechanisms and mediators, the readers will gain knowledge of the common ground in metastasis from a single source. Finally, an introductory chapter provides a clinical perspective of the problems presented by metastatic tumours for diagnosis and treatment. The work presented here is directed to researchers in tumour biology with a developing interest in metastatic dissemination as well as medical and graduate students seeking to expand and integrate the notions acquired in basic cancer biology and oncology courses.
| Author | : Georg F. Weber |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 643 |
| Release | : 2007-09-12 |
| Genre | : Medical |
| ISBN | : 1402060165 |
This book describes molecular processes whose deregulation is important in the formation of tumors. The material is developed from basic cell signaling pathways to their roles in the clinical manifestation of specific cancers. Topics covered include molecular events intrinsic to tumor cells (leading to growth deregulation, extended lifespan, and the ability to invade surrounding tissue), protective mechanisms that prevent transformation (including DNA repair and epigenetic regulation), tumor-host interactions (with the endocrine system, the immune system, and blood vessel formation), and the underlying molecular defects of individual cancers.
| Author | : David A. Frank |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 358 |
| Release | : 2002-12-31 |
| Genre | : Medical |
| ISBN | : 1402073402 |
One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."
| Author | : Alexander Birbrair |
| Publisher | : Springer Nature |
| Total Pages | : 196 |
| Release | : 2020-10-29 |
| Genre | : Medical |
| ISBN | : 3030471896 |
Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on how different signaling pathways are important in the tumor microenvironment. Multiple signaling pathways are covered, including Src, Neuregulin, Adenosine, TGFβ, Androgen, Wnt, and more. Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Signaling Pathways – Part B is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
| Author | : Alexander Birbrair |
| Publisher | : Springer Nature |
| Total Pages | : 173 |
| Release | : 2020-10-29 |
| Genre | : Medical |
| ISBN | : 3030502244 |
This book provides a comprehensive overview of the latest research on the molecular players in the tumor microenvironment, including MicroRNAs, estrogen, Caveolin-1, Nitric Oxide, RANK/RANKL signaling, , COX-2 Signaling, Renin–angiotensin system, and more. Taken alongside its companion volumes, Tumor Microenvironment: Molecular Players – Part B updates us on what we know about the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
| Author | : Jian Huang |
| Publisher | : Frontiers Media SA |
| Total Pages | : 229 |
| Release | : 2022-02-14 |
| Genre | : Science |
| ISBN | : 2889742555 |
| Author | : Mandi Murph |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 414 |
| Release | : 2015-04-01 |
| Genre | : Medical |
| ISBN | : 9535120360 |
Melanoma - Current Clinical Management and Future Therapeutics serves as an advanced course in melanoma or an addendum to further polish expertise. Sections of the book include a thorough introduction on epidemiology and disease, the current surgical management of melanoma and lymph node dissection, immunotherapy along with drug toxicities and emerging research topics, like RAGE and autotaxin, that have potential therapeutic applications. The chapters in this book explore the most common subtype of melanoma, cutaneous disease, as well as a rare form, acral lentiginous melanoma and even canine tumors. Experts from around the globe contributed chapters, most of which have visual illustrations to depict aspects of disease management and therapy, allowing readers to grasp the advanced concepts presented.
