Tumor Blood Circulation PDF Download
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Author | : Hans-Inge Peterson |
Publisher | : CRC Press |
Total Pages | : 320 |
Release | : 2020-04-15 |
Genre | : Medical |
ISBN | : 1000083551 |
Download Tumor Blood Circulation Book in PDF, ePub and Kindle
First Published in 1979, this book offers a full, insight into the relationship between malignant tumors and blood flow. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for students of oncology, and other practitioners in their respective fields.
Author | : M. Molls |
Publisher | : Springer Verlag |
Total Pages | : 238 |
Release | : 2000-01-01 |
Genre | : Medical |
ISBN | : 9783540669944 |
Download Blood Perfusion and Microenvironment of Human Tumors Book in PDF, ePub and Kindle
This text explores the most recent advances in research on adaptations and responses to the physical environment among the major plant groups found in tropical ecosystems. Fundamental processes provide the organizational framework for the book. Its four main sections include: i) acquisition, transport and loss of water, ii) carbon acquisition and regulation of photosynthetic gas exchange, iii) nutrient acquisition and use, iv) energy balance and adaptation to temperature extremes. Concise but informative explanations of fundamental concepts at the beginning of each chapter allow those not familiar with the spcialized terminology to grasp the nuances of each topic before becoming immersed in the more detailed analyses processes and case studies taht follow. The book ends by suggesting that the bewildering plant species diversity in tropical ecosystems does not necessarily reflect an intractable range of physiological diversity.
Author | : Trachette L. Jackson |
Publisher | : Springer Science & Business Media |
Total Pages | : 411 |
Release | : 2011-11-23 |
Genre | : Medical |
ISBN | : 146140052X |
Download Modeling Tumor Vasculature Book in PDF, ePub and Kindle
To profoundly understand biology and harness its intricacies for human benefit and the mitigation of human harm requires cross-disciplinary approaches that incorporate sophisticated computational and mathematical modeling techniques. These integrative strategies are essential to achieve rapid and significant progress in issues, in health and disease, which span molecular, cellular and tissue levels. The use of mathematical models to describe various aspects of tumor growth has a very long history, dating back over six decades. Recently, however, experimental and computational advances have improved our in the understanding of how processes act at multiple scales to mediate the development of tumor vasculature and drive the advancement of cancer. This book will showcase the development and utilization of new computational and mathematical approaches to address multiscale challenges associated with tumor vascular development. In Part I: Cell Signaling and Molecular Aspects of Tumor Blood Vessel Formation, it will be come clear that mathematical modeling can help to biochemically and biomechanically phenotype one of the most important cell types involved in cancer progression: vascular endothelial cells. When subverted by the tumor modulated environment, vascular endothelial cells form a new vascular supply capable of nourishing and translocating cancer cells to other tissues. The models in Part I illustrate the importance of quantitative approaches for gaining a deeper understanding of how normal and abnormal aspects of signal integration culminate in the cell proliferation, migration, and survival decisions that result in pathological tumor angiogenesis. The focus of Part II is the angiogenesis cascade and all of its complexities. Successful angiogenesis is mediated by the intricate interplay between biochemical and biomechanical mechanisms, including cell-cell and cell-matrix interactions, cell surface receptor binding, and intracellular signal transduction. A major challenge facing the cancer research community is to integrate known information in a way that improves our understanding of the principal underpinnings driving tumor angiogenesis and that will advance efforts aimed at the development of new therapies for treating cancer. The chapters in Part II will highlight several mathematical and computational approaches for that can potentially address this challenge. While the first two thirds of the book’s chapters demonstrate how important insights can be gained by studying cell signaling and vascular morphology and function, the series of chapters in Part III: Whole Organ Modeling of Tumor Growth and Vasculature, will integrate vasculature development with tumor growth dynamics. These two processes strongly depend on one another in ways that can only be theoretically investigated by biophysical approaches that cut across several levels of biological organization and describe both the tumor and the developing vasculature as they co-evolve. The purpose of this edited volume is not to provide a comprehensive review of all modeling efforts that address tumor vascular modeling; instead, a variety of interesting and innovative mathematical modeling approaches for understanding the development and effects of tumor vasculature are highlighted in order to illustrate some of the emerging trends in the field.
Author | : Hugh A. McAllister |
Publisher | : |
Total Pages | : 164 |
Release | : 1978 |
Genre | : Cardiovascular system |
ISBN | : |
Download Tumors of the Cardiovascular System Book in PDF, ePub and Kindle
Author | : Allen Burke |
Publisher | : Afip |
Total Pages | : 248 |
Release | : 1996 |
Genre | : Medical |
ISBN | : |
Download Tumors of the Heart and Great Vessels Book in PDF, ePub and Kindle
Author | : F. William Orr |
Publisher | : CRC Press |
Total Pages | : 326 |
Release | : 1991-07-25 |
Genre | : Medical |
ISBN | : 9780849361548 |
Download Microcirculation in Cancer Metastasis Book in PDF, ePub and Kindle
Although mechanisms involved in the spread of cancer have been the subject of a major research endeavor over the past decade, metastatic tumors still account for significant clinical morbidity and the failure of cancer treatment. Not only are the vascular pathways the most common route for the dissemination of cancer cells, but interactions between the cells and the circulation act as important rate-regulators for the metastatic process. This authoritative, multi-authored volume addresses the importance of microcirculation in cancer metastasis. The book begins with up-to-date reviews on the biology of endothelial cells and the structure and physiology of the normal and tumor microcirculations, and then emphasizes interactions between components of the microcirculation and cancer cells. Metastasis is discussed through chapters exploring the entry of cancer cells into the circulation, the biophysics and morphology of cancer cell traffic and arrest, interactions with host cells and the basement membranes, and angiogenesis. This fascinating book will interest oncologists, pathologists, and students of metastasis or the microcirculation.
Author | : Domenico Ribatti |
Publisher | : Springer Science & Business Media |
Total Pages | : 122 |
Release | : 2012-09-28 |
Genre | : Medical |
ISBN | : 9400749368 |
Download Morphofunctional Aspects of Tumor Microcirculation Book in PDF, ePub and Kindle
Blood vessels of tumors display many structural and functional abnormalities. Their unusual leakiness, potential for rapid growth and remodeling, and expression of distinctive surface molecules mediate the dissemination of tumor cells in the bloodstream and maintain the tumor microenvironment. Like normal blood vessels, they consist of endothelial cells, mural cells and their enveloping basement membrane. Common features, irrespective of their origin, size and growth pattern, are absent hierarchy, formation of large-caliber sinusoidal vessels, markedly heterogeneous density, increased permeability, decreased and abnormal pericyte-endothelial cell adhesion, irregular basement membrane structure, and the incorporation of bone-marrow-derived endothelial progenitor cells in the microvasculature. A number of specific tumor endothelial markers have been identified, as well as chromosomal abnormalities. These markers may be used to deliver drugs specifically and selectively to the tumor microvasculature.
Author | : Domenico Ribatti |
Publisher | : Academic Press |
Total Pages | : 198 |
Release | : 2020-01-21 |
Genre | : Science |
ISBN | : 0128194944 |
Download Tumor Vascularization Book in PDF, ePub and Kindle
Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: the first one, General Mechanisms, discusses different vessel growth mechanisms, such as sprouting angiogenesis, non-angiogenesis dependent growth, intussusceptive microvascular growth, vascular co-option and vasculogenic mimicry. The second and third parts, entitled Clinical Implications and Therapeutic Implications are dedicated to translating recent findings in this field to patient treatment and healthcare. This book is a valuable source for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in tumor progression and blood vessels. Explains new, non-orthodox concepts recently developed and related to the modality of growth of tumor blood vessels Provides information on the types of angiogenesis, non-angiogenesis dependent growth and vascular co-option, discussing both their similarities and differences Encompasses a discussion on clinical implications of tumor vascularization to translate research findings into treatment
Author | : Peter Vaupel |
Publisher | : |
Total Pages | : 340 |
Release | : 1991 |
Genre | : Tumors |
ISBN | : 9783437306754 |
Download Tumor Blood Supply and Metabolic Microenvironment Book in PDF, ePub and Kindle
Author | : Nihon Gan Chiryō Gakkai |
Publisher | : |
Total Pages | : |
Release | : |
Genre | : |
ISBN | : |
Download Increase of Blood Flow in Tumor Tissue and Significance at Cancer Diagnosis Book in PDF, ePub and Kindle