Trp Ion Channel Function In Sensory Transduction And Cellular Signaling Cascades PDF Download
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| Author | : Wolfgang B. Liedtke, MD, PH.D. |
| Publisher | : CRC Press |
| Total Pages | : 502 |
| Release | : 2006-09-29 |
| Genre | : Medical |
| ISBN | : 1420005847 |
Download TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades Book in PDF, ePub and Kindle
Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st
| Author | : Veit Flockerzi |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 610 |
| Release | : 2007-02-07 |
| Genre | : Medical |
| ISBN | : 3540348913 |
Download Transient Receptor Potential (TRP) Channels Book in PDF, ePub and Kindle
This volume provides up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field have written 35 essays which describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression.
| Author | : Peter C. Ruben |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 328 |
| Release | : 2014-04-15 |
| Genre | : Medical |
| ISBN | : 3642415881 |
Download Voltage Gated Sodium Channels Book in PDF, ePub and Kindle
A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior. Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel function. This volume of the Handbook of Experimental Pharmacology will explore sodium channels from the perspectives of their biophysical behavior, their structure, the drugs and toxins with which they are known to interact, acquired and inherited diseases that affect sodium channels and the techniques with which their biophysical and structural properties are studied.
| Author | : Raymond S. Sinatra |
| Publisher | : Cambridge University Press |
| Total Pages | : 729 |
| Release | : 2009-04-27 |
| Genre | : Medical |
| ISBN | : 0521874912 |
Download Acute Pain Management Book in PDF, ePub and Kindle
This textbook provides an overview of pain management useful to specialists as well as non-specialists, surgeons, and nursing staff.
| Author | : Fatima Shad Kaneez |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 204 |
| Release | : 2018-10-10 |
| Genre | : Science |
| ISBN | : 1789842271 |
Download Ion Channels in Health and Sickness Book in PDF, ePub and Kindle
Ion channels are proteins that make pores in the membranes of excitable cells present both in the brain and the body. These cells are not only responsible for converting chemical and mechanical stimuli into the electrical signals but are also liable for monitoring vital functions. All our activities, from the blinking of our eyes to the beating of our heart and all our senses from smell to sight, touch, taste and hearing are regulated by the ion channels. This book will take us on an expedition describing the role of ion channels in congenital and acquired diseases and the challenges and limitations scientist are facing in the development of drugs targeting these membrane proteins.
| Author | : Bernd Nilius |
| Publisher | : Springer |
| Total Pages | : 569 |
| Release | : 2014-06-24 |
| Genre | : Medical |
| ISBN | : 331905161X |
Download Mammalian Transient Receptor Potential (TRP) Cation Channels Book in PDF, ePub and Kindle
In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.
| Author | : Nicholas Sperelakis |
| Publisher | : Elsevier |
| Total Pages | : 1262 |
| Release | : 2012-12-02 |
| Genre | : Science |
| ISBN | : 0080574556 |
Download Cell Physiology Source Book Book in PDF, ePub and Kindle
This authoritative book gathers together a broad range of ideas and topics that define the field. It provides clear, concise, and comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics. The Third Edition contains substantial new material. Most chapters have been thoroughly reworked. The book includes chapters on important topics such as sensory transduction, the physiology of protozoa and bacteria, the regulation of cell division, and programmed cell death. Completely revised and updated - includes 8 new chapters on such topics as membrane structure, intracellular chloride regulation, transport, sensory receptors, pressure, and olfactory/taste receptors Includes broad coverage of both animal and plant cells Appendixes review basics of the propagation of action potentials, electricity, and cable properties Authored by leading experts in the field Clear, concise, comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics
| Author | : Brendan J. Canning |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 623 |
| Release | : 2009-08-05 |
| Genre | : Medical |
| ISBN | : 354079090X |
Download Sensory Nerves Book in PDF, ePub and Kindle
The intention of this book is to provide a comprehensive and contemporary review of the biology of sensory nerves. The book is unique, as it comprehensively covers the role of sensory nerves across many therapeutic areas.
| Author | : Tomohiro Kurosaki |
| Publisher | : Springer |
| Total Pages | : 231 |
| Release | : 2015-12-26 |
| Genre | : Medical |
| ISBN | : 3319261339 |
Download B Cell Receptor Signaling Book in PDF, ePub and Kindle
This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.
| Author | : Ruth Eatock |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 465 |
| Release | : 2006-07-01 |
| Genre | : Science |
| ISBN | : 0387317066 |
Download Vertebrate Hair Cells Book in PDF, ePub and Kindle
The Springer Handbook of Auditory Research presents a series of compreh- sive and synthetic reviews of the fundamental topics in modern auditory - search. The volumes are aimed at all individuals with interests in hearing research including advanced graduate students, postdoctoral researchers, and clinical investigators. The volumes are intended to introduce new investigators to important aspects of hearing science and to help established investigators to better understand the fundamental theories and data in ?elds of hearing that they may not normally follow closely. Each volume presents a particular topic comprehensively, and each serves as a synthetic overview and guide to the literature. As such, the chapters present neither exhaustive data reviews nor original research that has not yet appeared in peer-reviewed journals. The volumes focus on topics that have developed a solid data and conceptual foundation rather than on those for which a literature is only beginning to develop. New research areas will be covered on a timely basis in the series as they begin to mature.
