Trends In Monoclonal Antibody Research PDF Download
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| Author | : Marie A. Simmons |
| Publisher | : Nova Publishers |
| Total Pages | : 160 |
| Release | : 2005 |
| Genre | : Medical |
| ISBN | : 9781594545504 |
Download Trends in Monoclonal Antibody Research Book in PDF, ePub and Kindle
This new and important international source of information brings together leading-edge research dedicated to monoclonal antibodies. Monoclonal antibodies (MABs) are: antibodies of exceptional purity and specificity; components of the immune system; able to recognise and bind to a specific antigen. Monoclonal antibodies are currently utilised in many diagnostic procedures, including: measuring protein and drug levels in serum; typing tissue and blood; identifying infectious agents; identifying clusters of differentiation for the classification and follow-up therapy of leukaemias and lymphomas; identifying tumour antigens and auto-antibodies; identifying the specific cells involved in the immune response; identifying and quantifying hormones. For example, monoclonal antibodies (MABs or MOABs) work on cancer cells in the same way natural antibodies work, by identifying and binding to the target cells. They then alert other cells in the immune system to the presence of the cancer cells. MABs are specific for a particular antigen-one designed for a B-cell lymphoma will not work on cells for ovarian cancer cells for example.
| Author | : Steven J. Shire |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 348 |
| Release | : 2009-11-11 |
| Genre | : Medical |
| ISBN | : 038776643X |
Download Current Trends in Monoclonal Antibody Development and Manufacturing Book in PDF, ePub and Kindle
Monoclonal antibodies represent one of the fastest growing areas of new drug development within the pharmaceutical industry. Several blockbuster products have been approved over the past several years including Rituxan, Remicade, Avastin, Humira, and Herceptin. In addition, over 300 new drugs are currently in clinical trials. With both large, established biotechnology companies and small start-ups involved in the development of this important class of molecules, monoclonal antibodies products will become increasingly prevalent over the next decade. Recently the regulatory review of monoclonal antibodies has been moved from Center for Biologics and Research to the Center for Drug Evaluation and Research (CDER) division of the US Food and Drug Administration. It is anticipated that CDER will expect a certain minimal amount of data to be provided as more of these products move through the regulatory pipeline. Current Trends in Monoclonal Antibody Development and Manufacturing will provide readers with an understanding of what is currently being done in the industry to develop, manufacture, and release monoclonal antibody products and what will be required for a successful regulatory submission.
| Author | : Marie A. Simmons |
| Publisher | : Nova Publishers |
| Total Pages | : 186 |
| Release | : 2005 |
| Genre | : Medical |
| ISBN | : 9781594542473 |
Download Monoclonal Antibodies Book in PDF, ePub and Kindle
This new and important international source of information beings together leading-edge research dedicated to monoclonal antibodies. Monoclonal antibodies (MAbs) are: antibodies of exceptional purity and specificity; components of the immune system; able to recognise and bind to a specific antigen. Monoclonal antibodies are currently utilised in many diagnostic procedures, including: measuring protein and drug levels in serum; typing tissue and blood; identifying infectious agents; identifying clusters of differentiation for the classification and follow-up therapy of leukaemias and lymphomas; identifying tumour antigens and auto-antibodies; identifying the specific cells involved in the immune response; identifying and quantifying hormones. For example, monoclonal antibodies (MABs or MOABs) work on cancer cells in the same way natural antibodies work, by identifying and binding to the target cells. They then alert other cells in the immune system to the presence of the cancer cells. MABs are specific for a particular antigen-one designed for a B-cell lymphoma will not work on cells for ovarian cancer cells for example.
| Author | : Committee on Methods of Producing Monoclonal Antibodies |
| Publisher | : National Academies Press |
| Total Pages | : 74 |
| Release | : 1999-05-20 |
| Genre | : Science |
| ISBN | : 0309519047 |
Download Monoclonal Antibody Production Book in PDF, ePub and Kindle
The American Anti-Vivisection Society (AAVS) petitioned the National Institutes of Health (NIH) in early 1997 to prohibit the use of an animal in the production of mAb (monoclonal antibodies). NIH responded late in 1997, asserting that continued use of the mouse method for producing mAb was scientifically required. In a second petition, in early 1998, AAVS did not accept the NIH response. NIH asked the National Research Council to form a committee to study this issue. The Committee on Methods of Producing Monoclonal Antibodies was composed of 11 experts with extensive experience in biomedical research, laboratory animal medicine, pain research, animal welfare, and patient advocacy. The committee was asked to determine whether there is a scientific necessity for producing mAb by the mouse method and, if so, to recommend ways to minimize any pain or distress that might be associated with the method. The committee was also to determine whether there are regulatory requirements for the mouse method and to summarize the current stage of development of tissue-culture methods.
| Author | : Kenneth C. McCullough |
| Publisher | : Cambridge University Press |
| Total Pages | : 401 |
| Release | : 1990-04-19 |
| Genre | : Medical |
| ISBN | : 0521258901 |
Download Monoclonal Antibodies in Biotechnology Book in PDF, ePub and Kindle
Monoclonal antibodies are one of the most exciting developments in biotechnology in recent years; this book provides a comprehensive description of principles, methodologies and applications of this powerful technology to modern science and industry.
| Author | : James W. Goding |
| Publisher | : |
| Total Pages | : 344 |
| Release | : 1986 |
| Genre | : Medical |
| ISBN | : |
Download Monoclonal Antibodies Book in PDF, ePub and Kindle
This book represents the distillation and critical evaluation of many hundreds of publications relating to the production and use of antibodies. Therefore it is restricted to the "core" techniques of production and handling of antibodies, and their use in studies of antigen analysis, purification and localization.
| Author | : Uwe Gottschalk |
| Publisher | : John Wiley & Sons |
| Total Pages | : 849 |
| Release | : 2017-03-07 |
| Genre | : Medical |
| ISBN | : 1119126932 |
Download Process Scale Purification of Antibodies Book in PDF, ePub and Kindle
Promoting a continued and much-needed renaissance in biopharmaceutical manufacturing, this book covers the different strategies and assembles top-tier technology experts to address the challenges of antibody purification. • Updates existing topics and adds new ones that include purification of antibodies produced in novel production systems, novel separation technologies, novel antibody formats and alternative scaffolds, and strategies for ton-scale manufacturing • Presents new and updated discussions of different purification technologies, focusing on how they can address the capacity crunch in antibody purification • Emphasizes antibodies and innovative chromatography methods for processing
| Author | : Stefan Dübel |
| Publisher | : John Wiley & Sons |
| Total Pages | : 2538 |
| Release | : 2014-12-03 |
| Genre | : Science |
| ISBN | : 3527329374 |
Download Handbook of Therapeutic Antibodies Book in PDF, ePub and Kindle
Dieses Nachschlagewerk zu therapeutischen Antikörpern sucht auch in der komplett überarbeiteten 2. Auflage seinesgleichen und bietet 30 % neue Inhalte zu Entwicklung, Herstellung und therapeutischen Anwendungen dieser Biomoleküle.
| Author | : Yuti Chernajovsky |
| Publisher | : Springer |
| Total Pages | : 380 |
| Release | : 2007-11-22 |
| Genre | : Medical |
| ISBN | : 9783540732587 |
Download Therapeutic Antibodies Book in PDF, ePub and Kindle
This essential work, edited by two researchers at London’s famous Queen Mary’s medical school targets one of the most important areas in medical development today. These days, antibody therapeutics are the treatment of choice for several autoimmune and oncological conditions. They are, indeed, becoming the molecules of choice for further combination therapies and cell engineering. In this timely work, a slew of expert in the field of drug development summarize all the current developments and clinical successes.
| Author | : |
| Publisher | : ScholarlyEditions |
| Total Pages | : 202 |
| Release | : 2012-01-09 |
| Genre | : Medical |
| ISBN | : 1464928428 |
Download Monoclonal Antibodies: Advances in Research and Application: 2011 Edition Book in PDF, ePub and Kindle
Monoclonal Antibodies: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Monoclonal Antibodies. The editors have built Monoclonal Antibodies: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Monoclonal Antibodies in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Monoclonal Antibodies: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
