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Treatment of Bone and Soft Tissue Sarcomas

Treatment of Bone and Soft Tissue Sarcomas
Author: Per-Ulf Tunn
Publisher: Springer Science & Business Media
Total Pages: 372
Release: 2008-12-28
Genre: Medical
ISBN: 3540779604
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Bone and soft tissue sarcomas represent only about 2% of all malignancies; however, their treatment – with the goal of curing the patient while preserving the functionality of the affected body part – can, unlike other malignancies, only be successful with therapy concepts devised by interdisciplinary teams. This volume provides an extensive up-to-date overview of the specific diagnostics and current treatment standards of these rare entities, presenting the various limb-sparing modalities for patients with bone and soft tissue sarcomas with special regard to innovative reconstructive options. The evaluation of quality of life based on validated scores and the individual methods of coping with the illness through creative artistic projects are also acknowledged and integrated in the whole concept.

Forging a Poison Prevention and Control System

Forging a Poison Prevention and Control System
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 369
Release: 2004-09-16
Genre: Medical
ISBN: 0309091942
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Poisoning is a far more serious health problem in the U.S. than has generally been recognized. It is estimated that more than 4 million poisoning episodes occur annually, with approximately 300,000 cases leading to hospitalization. The field of poison prevention provides some of the most celebrated examples of successful public health interventions, yet surprisingly the current poison control "system" is little more than a loose network of poison control centers, poorly integrated into the larger spheres of public health. To increase their effectiveness, efforts to reduce poisoning need to be linked to a national agenda for public health promotion and injury prevention. Forging a Poison Prevention and Control System recommends a future poison control system with a strong public health infrastructure, a national system of regional poison control centers, federal funding to support core poison control activities, and a national poison information system to track major poisoning epidemics and possible acts of bioterrorism. This framework provides a complete "system" that could offer the best poison prevention and patient care services to meet the needs of the nation in the 21st century.

The Toxin Solution

The Toxin Solution
Author: Joseph Pizzorno
Publisher: HarperCollins
Total Pages: 226
Release: 2017-02-21
Genre: Health & Fitness
ISBN: 0062427474
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Eliminate avoidable toxins, mitigate the effects of those you can’t avoid, and enjoy a longer life with this essential health guide from a pioneer in integrative medicine, Dr. Joe Pizzorno—the author, teacher, practitioner, and founder of Bastyr University, the country’s first and largest fully accredited university of natural medicine. Dr. Joe Pizzorno is convinced that lifelong good health rests on two key determinants: your exposure to toxins and your ability to process them in your body. While lifestyle, diet, and genetics all play a major role in well-being, many symptoms of declining health and chronic disease are rooted in toxic overload—our exposure to a barrage of chemicals, heavy metals, radiation, electromagnetic frequencies, and pollution that are the byproducts of modern life. While the human body has an innate capacity to detoxify, it cannot cope with the elevated levels of toxins we are exposed to today. Most alarmingly, this toxic overload has helped transform once rare diseases into epidemics affecting people of all ages. In The Toxin Solution, Dr. Pizzorno provides the proven detox and tailored methods he has developed to heal toxic overload and restore health in just eight weeks. With this essential guide you will learn how to: Avoid toxins in food and the products you use; Mend your gut and prepare for detox; Support your body in releasing the chemicals; Repair some of the damage toxins have caused. Fortunately, our bodies have a tremendous capacity for healing and recovery. With The Toxin Solution you will discover how releasing and avoiding toxins can help you to feel better today—and every day for the rest of your life.

Venoms to Drugs

Venoms to Drugs
Author: Glenn King
Publisher: Royal Society of Chemistry
Total Pages: 338
Release: 2015-02-11
Genre: Science
ISBN: 1849736634
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This unique book will provide an up to date and comprehensive account of the potential of peptides and proteins from animal venoms as possible therapeutics. The pharmaceutical industry has become increasingly interested in biologics from animal venoms as a potential source for therapeutic agents in recent years, with a particularly emphasis on peptides. To date six drugs derived from venom peptides or proteins have been approved by the FDA, with nine further agents currently being investigated in clinical trials. In addition to these drugs in approved or advanced stages of development, many more peptides and proteins are being studied in varying stages of preclinical development. Topics covered include chemistry and structural biology of animal venoms, proteomic and transcriptomic approaches to drug discovery, bioassays, high-throughput screens and target identification, and reptile, scorpion, spider and cone snail venoms as a platform for drug development. Case studies are used to illustrate methods and successes and highlight issues surrounding administration and other important lessons that have been learnt from the development of approved therapeutics based on venoms. The first text to focus on this fascinating area and bridging an important gap, this book will provide the reader with essential and current knowledge on this fast-developing area. Venoms to Drugs will find wide readership with researchers working in academia and industry working in all medicinal and pharmaceutical areas.

Heart and Toxins

Heart and Toxins
Author: Dr. Meenakshisundaram Sundaram Ramachandran
Publisher: Elsevier
Total Pages: 668
Release: 2014-08-12
Genre: Science
ISBN: 0124165990
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The Heart and Toxins brings together global experts to provide the latest information and clinical trials that make the connection between genetic susceptibility, gene expression, and environmental factors in cardiovascular diseases. This unique reference, edited by renowned cardiologist Meenakshi Sundaram Ramachandran, solves the problem of managing multiple clinical cases of cardiovascular toxicity. It allows connections to be made between research, diagnosis, and treatment to avoid higher morbidity and mortality rates as a result of cardiovascular toxicity. Structured to bring together exploration into the epidemiology, molecular mechanism, pathogenesis, environmental factors and management in cardiovascular toxins” Included various topics on cardiovascular toxins such as plant, chemical, animal, nanomaterial and marine biology induced cardiac damage – which are new ideas discussed in detail Comprehensive chapters on the cardiovascular toxicity from drugs, radiotherapy and radiological imaging Enables you to manage multiple clinical cases of cardiovascular toxicity Outlined conclusions at the end of each chapter providing “key learning points” to help you organize the chapter’s details without losing insight

Healing with Poisons

Healing with Poisons
Author: Yan Liu
Publisher: University of Washington Press
Total Pages: 278
Release: 2021-06-22
Genre: History
ISBN: 0295749016
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Open access edition: DOI 10.6069/9780295749013 At first glance, medicine and poison might seem to be opposites. But in China’s formative era of pharmacy (200–800 CE), poisons were strategically employed as healing agents to cure everything from abdominal pain to epidemic disease. Healing with Poisons explores the ways physicians, religious figures, court officials, and laypersons used toxic substances to both relieve acute illnesses and enhance life. It illustrates how the Chinese concept of du—a word carrying a core meaning of “potency”—led practitioners to devise a variety of methods to transform dangerous poisons into effective medicines. Recounting scandals and controversies involving poisons from the Era of Division to the Tang, historian Yan Liu considers how the concept of du was central to how the people of medieval China perceived both their bodies and the body politic. He also examines the wide range of toxic minerals, plants, and animal products used in classical Chinese pharmacy, including everything from the herb aconite to the popular recreational drug Five-Stone Powder. By recovering alternative modes of understanding wellness and the body’s interaction with foreign substances, this study cautions against arbitrary classifications and exemplifies the importance of paying attention to the technical, political, and cultural conditions in which substances become truly meaningful. Healing with Poisons is freely available in an open access edition thanks to TOME (Toward an Open Monograph Ecosystem) and the generous support of the University of Buffalo.

Emergency Medical Services

Emergency Medical Services
Author: Jane H. Brice
Publisher: John Wiley & Sons
Total Pages: 1184
Release: 2021-08-12
Genre: Medical
ISBN: 111975626X
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The two-volume Emergency Medical Services: Clinical Practice and Systems Oversight delivers a thorough foundation upon which to succeed as an EMS medical director and prepare for the NAEMSP National EMS Medical Directors Course and Practicum. Focusing on EMS in the 'real world', the book offers specific management tools that will be useful in the reader's own local EMS system and provides contextual understanding of how EMS functions within the broader emergency care system at a state, local, and national level. The two volumes offer the core knowledge trainees will need to successfully complete their training and begin their career as EMS physicians, regardless of the EMS systems in use in their areas. A companion website rounds out the book's offerings with audio and video clips of EMS best practice in action. Readers will also benefit from the inclusion of: A thorough introduction to the history of EMS An exploration of EMS airway management, including procedures and challenges, as well as how to manage ventilation, oxygenation, and breathing in patients, including cases of respiratory distress Practical discussions of medical problems, including the challenges posed by the undifferentiated patient, altered mental status, cardiac arrest and dysrhythmias, seizures, stroke, and allergic reactions An examination of EMS systems, structure, and leadership

Detoxification and Healing

Detoxification and Healing
Author: Sidney MacDonald Baker
Publisher: McGraw Hill Professional
Total Pages: 224
Release: 2003-09-11
Genre: Sports & Recreation
ISBN: 0071812547
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Detoxification promotes wellness by ridding the body of poisons that can lead to a host of health problems ranging from fatigue and depression to cancer and diabetes. This revised edition of the popular nutrition-based health guide presents new advice and up-to-date information on detoxification and healing. In clear language, the author explains body chemistry, how detoxification works, and why it is so important. He discusses new medications, vitamin and mineral supplements, delayed food allergies, the dangers of mercury and aluminum poisoning, and much more.

Antidotes to Toxins and Drugs

Antidotes to Toxins and Drugs
Author: Mihnea-Alexandru Găman
Publisher: Elsevier
Total Pages: 487
Release: 2023-11-25
Genre: Science
ISBN: 0323859968
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Antidotes to Toxins and Drugs: From Natural Sources to Drug Discovery in Toxicology presents recent advances in the discovery of natural antidotes to toxins, drug intoxications and overdoses in pharmacology, drug discovery and toxicology. The text provides detailed information about toxins and their natural antidotes, along with the identification and screening of antidotes for drug intoxications and overdoses. Written by a global team of experts, it describes the potential uses of natural products in toxicology and their applications in medicine and in the pharmaceutical sciences. This book will be a key resource for drug developers, medicinal chemists and toxicologists, among others.Sections shine a particular focus on mechanisms of action, various principles in pharmacokinetics and pharmacodynamics terms, and possible sources and synthesis techniques for these phytochemicals. Details recent advances in the discovery of natural antidotes from medicinal plants and phytochemicals Includes advances in the discovery of antidotes to drug intoxications and overdoses Describes modern screening assays for toxins and drug intoxications Features information on recent advances in toxicology

Removal of Toxic Pollutants through Microbiological and Tertiary Treatment

Removal of Toxic Pollutants through Microbiological and Tertiary Treatment
Author: Maulin P Shah
Publisher: Elsevier
Total Pages: 622
Release: 2020-08-20
Genre: Technology & Engineering
ISBN: 0128216824
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Removal of Toxic Pollutants through Microbiological and Tertiary Treatment: New Perspectives offers a current account of existing advanced oxidation strategies - including their limitations, challenges, and potential applications - in removing environmental pollutants through microbiological and tertiary treatment methods. The book introduces new trends and advances in environmental bioremediation technology, with thorough discussion of recent developments in the field. Updated information as well as future research directions in the field of bioremediation of industrial wastes is included. This book is an indispensable guide to students, researchers, scientists, and professionals working in fields such as microbiology, biotechnology, environmental sciences, eco-toxicology, and environmental remediation. The book also serves as a helpful guide for waste management professionals and those working on the biodegradation and bioremediation of industrial wastes and environmental pollutants for environmental sustainability. Introduces various treatment schemes, including microbiological and tertiary technologies for bioremediation of environmental pollutants and industrial wastes Includes pharmaceutical wastewater, oil refinery wastewater, distillery wastewater, tannery wastewater, textile wastewater, mine tailing wastes, plastic wastes, and more Describes the role of relatively new treatment technologies and their approaches in bioremediation, including molecular and protein engineering technologies, microbial enzymes, bio surfactants, plant-microbe interactions, and genetically engineered organisms Provides many advanced technologies in the field of bioremediation and phytoremediation, including electro-bioremediation technology, microbial fuel cell technology, nano-bioremediation technology, and phytotechnologies