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| Author | : Richard J. Gralla |
| Publisher | : |
| Total Pages | : 160 |
| Release | : 1989 |
| Genre | : Medical |
| ISBN | : |
| Author | : David J. Stewart |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 544 |
| Release | : 2010-03-10 |
| Genre | : Medical |
| ISBN | : 160761524X |
Defining the Lung Cancer Problem 1 Lung cancer is the leading cause of cancer death in the world. It kills almost as many Americans as cancers of the breast, prostate, colon, rectum, pancreas, and 2 kidney combined, and accounts for 28.6% of all US cancer deaths. With an increase in the 5-year relative survival rate from 13% to only 16% in the more than 2 30 years from 1974 to the present, it will take us another 840 years to eradicate lung cancer deaths if we do not improve the current rate of progress. As discussed in this text, lung cancer prevention has received substantial att- tion. The decrease in smoking in recent decades has helped, but smoking is not the only problem. Lung cancer in people who have never smoked is currently the 5th 3 leading cause of cancer death in the United States. Several factors contribute to the lethality of lung cancer, including the rapidity of tumor growth, advanced stage at diagnosis (due to nonspecificity of early sy- toms and the uncertain efficacy of screening), early development of metastases, and resistance to therapy. Several chapters in this book discuss new molecular targets that may be potentially exploitable in the future, as well as discussing our track record to date in exploiting them.
| Author | : Hugh L'Etang |
| Publisher | : |
| Total Pages | : 148 |
| Release | : 1989 |
| Genre | : |
| ISBN | : |
| Author | : Rex White |
| Publisher | : American Medical Publishers |
| Total Pages | : 0 |
| Release | : 2023-09-26 |
| Genre | : Health & Fitness |
| ISBN | : |
Non-small cell lung cancer refers to a disease in which the cancer cells are formed in tissues of the lung. There are three common types of non-small cell lung cancer, namely, adenocarcinoma, squamous cell carcinoma and large cell carcinoma. Smoking cigars, pipes or cigarettes is the major cause of this disease. Radiation therapy, air pollution and pulmonary fibrosis are some other causes of non-small cell lung cancer. Some common symptoms of non-small cell lung cancer are chest pain, appetite loss, unexplained weight loss, tiredness, and swelling of face or the veins in the neck. Patients can be examined by certain diagnostic tests, like chest X-rays, blood or urine tests, sputum cytology, bronchoscopy, etc. Surgery is the major treatment for non-small cell lung cancer. Some other treatments include radiofrequency ablation, chemotherapy, and targeted drug therapy. This book provides comprehensive insights into the prevention, management and emerging therapies for non-small cell lung cancer. It presents researches and studies performed by experts across the globe. This book will prove to be immensely beneficial to students and researchers studying this medical condition.
| Author | : W.D. Travis |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 139 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3642600492 |
with contributions by Pathologists from 14 Countries
| Author | : Harvey I. Pass |
| Publisher | : Lippincott Williams & Wilkins |
| Total Pages | : 1056 |
| Release | : 2012-02-13 |
| Genre | : Medical |
| ISBN | : 1451152965 |
Thoroughly revised and updated, this Fourth Edition is the most comprehensive, current reference on lung cancer, with contributions from the world's foremost surgeons, radiation oncologists, medical oncologists, pulmonologists, and basic scientists. Coverage includes complete information on combined modality treatments for small cell and non-small cell lung cancer and on complications of treatment and management of metastases. Emphasis is also given to early detection, screening, prevention, and new imaging techniques. This edition has expanded thoracic oncology chapters including thymus, mesothelioma, and mediastinal tumors, more detailed discussion of targeted agents, and state-of-the-art information on newer techniques in radiotherapy. Other highlights include more international contributors and greater discussion of changes in lung cancer management in each region of the world. A new editor, Giorgio Scagliotti, MD from the University of Turin, has coordinated the accounts of European activities. A companion website includes the full text online and an image bank.
| Author | : Karen L. Reckamp |
| Publisher | : Springer |
| Total Pages | : 324 |
| Release | : 2016-08-17 |
| Genre | : Medical |
| ISBN | : 3319403893 |
This book describes the molecular mechanisms of lung cancer development and progression that determine therapeutic interventions in the era of genomics, when the rapid evolution in lung cancer diagnosis and treatment necessitates critical review of new results to integrate advances into practice. The text opens with background and emerging information regarding the molecular biology of lung cancer pathogenesis. Updated results regarding lung cancer prevention and screening are discussed, followed by chapters on diagnostic techniques and pathological evaluation. This leads on to a detailed presentation of treatment modalities, from surgery and radiation therapy to standard chemotherapy and targeted agents. The coverage includes resistance to therapy and the emergence of immunotherapy for lung cancer; in addition, the current evidence in respect of small cell lung cancer is summarized. The book presents insights from experts across disciplines to emphasize the importance of collaborative care. Advances in our understanding of issues in geriatric oncology and palliative care complete the comprehensive discussion of lung cancer.
| Author | : Junji Uchino |
| Publisher | : Frontiers Media SA |
| Total Pages | : 311 |
| Release | : 2022-02-24 |
| Genre | : Medical |
| ISBN | : 2889745147 |
| Author | : Joan H. Schiller |
| Publisher | : Karger Medical and Scientific Publishers |
| Total Pages | : 202 |
| Release | : 1997-01-01 |
| Genre | : Medical |
| ISBN | : 9783805565578 |
Lung cancer remains a major cause of cancer deaths throughout the world. It is an extremely lethal neoplasm: 80-90% of patients who develop lung cancer will die of their disease. The purpose of this book is to update cancer specialists, pulmonary physicians, thoracic surgeons and general practitioners about the many recent advances in the treatment, prevention and biology of lung cancer. Despite the overall poor prognosis for patients, a number of new chemotherapeutic drugs and regimens have been developed which result in a clinically meaningful improvement in survival for patients with nonsmall cell lung carcinoma. Four chapters in this book are devoted to reviewing these new drugs and drug combinations (paclitaxel, docetaxel, vinorelbine, gemcitabine, topoisomerase inhibitors). Advances in the management of locally advanced nonsmall cell and small cell lung cancer are considered, including combined-modality treatments using chemotherapy, surgery, and radiation therapy. Results of recent trials involving chemoprevention agents are also reported. Finally, the latest progress in understanding the molecular biology of this disease, and how it might impact on the clinical management of lung cancer patients, is discussed.
| Author | : Mary O'Brien |
| Publisher | : Karger Medical and Scientific Publishers |
| Total Pages | : 148 |
| Release | : 2022-02-28 |
| Genre | : Medical |
| ISBN | : 3318070106 |
Despite an overall decrease in tobacco use, lung cancer (80–85% of which is non-small-cell lung cancer [NSCLC]) is still the leading cause of cancer death in both men and women worldwide. Annual low-dose CT screening of high-risk individuals has the potential to detect early-stage tumors, which can usually be successfully treated with a combination of surgery, radiotherapy and chemotherapy and, in some cases, targeted therapy. However, most patients with NSCLC still present with advanced or metastatic disease. For these patients, initial therapy is guided by the tumor’s molecular characteristics and patient’s performance status. Targeted therapies have significantly improved clinical outcomes and, for some patients with no targetable genetic alterations, immunotherapy has demonstrated significant overall survival benefit. This insightful guide is designed to bring you up to speed with the latest developments and is important reading for all health professionals and medical trainees working in this fast-moving field. Table of Contents: • Prevention and screening • Diagnosis and staging • Surgery • Radiotherapy • Systemic therapy in non-metastatic NSCLC • Systemic therapy in advanced-stage/metastatic disease without a molecular driver • Personalized treatment in advanced NSCLC • Oligometastatic disease and brain metastases
