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| Author | : Chandana Haldar |
| Publisher | : Science Publishers |
| Total Pages | : 590 |
| Release | : 2002 |
| Genre | : Medical |
| ISBN | : |
This text includes recent literature on pineal research on reproduction, melatonin rhythm, carbohydrate metabolism and immunity.
| Author | : Mehmet Turget |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2012 |
| Genre | : Anatomy |
| ISBN | : 9781608767175 |
The pineal gland, epiphysis, is a small endocrine gland in the brain. since Descartes it is known organ, but in the past decade it has been the subject of much research and debate in recent years. Written and edited by leading international authorities in the field, it provides an in-depth review of knowledge of the developmental anatomy, imaging, benign and malignant neoplasms of the pineal gland, and their treatment by endoscopic techniques and surgical procedures. Moreover, the biological effects of melatonin, the chief product of pineal gland, and experimental pinealeactomy procedures in small animals are given. As a result, it gives clinicians and investigators current evidences and an outlook to future areas of study and to innovative therapeutic philosophies. This book represents the first comprehensive reference book on the pineal gland and its product melatonin.
| Author | : S. R. Pandi-Perumal |
| Publisher | : Nova Publishers |
| Total Pages | : 932 |
| Release | : 2007 |
| Genre | : Antioxidants |
| ISBN | : 9781600211218 |
Melatonin is a neurohormone produced in the brain by the pineal gland, from the amino acid tryptophan. Melatonin possesses antioxidant activity, and many of its proposed therapeutic or preventive uses are based on this property. This book presents a wide spectrum of research on melatonin.
| Author | : Franco Fraschini |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 230 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 146151911X |
This volume contains the written contributions to the proceedings of a workshop related to the pineal gland and its hormones, which was held in Erice, Italy, on June 7 -June 13, 1994. This series of workshops, which began in 1982 and which have been held at four-year intervals since that time, has provided important continuity for advancing the state of knowledge relating to this very important investigative area. The enthusiasm for these conferences has increased steadily, as reflected in the number of individuals applying to attend and in the input of individuals who participate in the meeting. The 1994 meeting was important because of its timeliness. In the two years preceding the meeting a number of revolutionary discoveries were made relative to the actions of the pineal hormone melatonin. The Xenopus melatonin receptor was cloned, melatonin was demonstrated to be a potent antioxidant, the significance of melatonin receptors at the level of pars tuberalis in the regulation of the hypothalamo-pituitary-gonadal axis was questioned, a number of melatonin receptor analogues were discovered and successfully utilized, the mechanisms by which melatonin retards initiation and promotion of cancer was further elucidated, the clinical aspects of the pineal gland was re-scrutinized. Reviews relating to each of these subjects, as well as many others, are contained in this proceedings book. This volume represents an up-to-date repository for the most recent information related to this rapidly advancing field.
| Author | : Franco Fraschini |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 321 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 1461537568 |
Research related to the pineal gland has advanced rapidly in the last three decades since the discovery of its most important hormone, melatonin. This indoleamine has been shown to have a large variety of effects in the organism; the bulk of these actions were initially thought to relate the pineal gland to the reproductive and endocrine systems. It is now apparent, however, that the physiologic interactions of the pineal and its hormones far transcend its control of endocrine function. One field of pineal research that has developed rapidly within the last 5 years has been the demonstration of its relationship to the immune system. Since the pineal gland is part of the central nervous system, these observations generally fall in the category of neuroimmunology, an area that, in its own right, has received a great deal of attention in the last decade. Thus, a NATO Advanced Study Course entitled "Role of Melatonin and Pineal Pep tides in Neuroimmunomodulation" was convened in Erice, Sicily, on June 3-9, 1990. This book is a result of the scientific presentations given at the workshop. The contributions to the book include mini-review articles which summarized the presentations of the invited speakers as well as a selected number of brief communications where the subject matter was in line with the theme of the Advanced Study Course.
| Author | : Josephine Arendt |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 364 |
| Release | : 1994-12-31 |
| Genre | : Science |
| ISBN | : 9780412536007 |
This volume provides the reader with an overview of an intriguing and interdisciplinary field of research. For the first time the mammalian pineal gland, its mode of action and its physiological effects are discussed in a comprehensive, single-authored work.
| Author | : Mehmet Turget |
| Publisher | : Nova Science Publishers |
| Total Pages | : 491 |
| Release | : 2011 |
| Genre | : Melatonin |
| ISBN | : 9781620818077 |
| Author | : Hing-Sing Yu |
| Publisher | : CRC Press |
| Total Pages | : 972 |
| Release | : 1992-12-21 |
| Genre | : Science |
| ISBN | : 9780849369001 |
Melatonin: Biosynthesis, Physiological Effects, and Clinical Applications provides a thorough review of recent advances in major areas of melatonin research. The book is arranged in a logical sequence, beginning with the history of melatonin and then proceeding to cover its biochemistry and secretion, physiological effects, and clinical significance. New findings and current concepts are emphasized, and a significant amount of previously unpublished data are included. The book will be an important reference for neurobiologists, cell biologists, ophthalmologists, endocrinologists, neuroendocrinologists, reproductive biologists, psychiatrists, and other researchers and clinicians interested in melatonin.
| Author | : Venkatramanujan Srinivasan |
| Publisher | : CRC Press |
| Total Pages | : 576 |
| Release | : 2014-10-15 |
| Genre | : Medical |
| ISBN | : 1482220091 |
There is growing interest in the field of melatonin research regarding its neurobiological mechanisms as well as its repercussions in clinical practice. Melatonin: Therapeutic Value and Neuroprotection explores melatonin’s neuroprotective effects and discusses the therapeutic potential of melatonin and melatonin agonists in treating neurodegenerative diseases and other ailments. Topics include: The basic aspects of melatonin’s physiology, including its production, bioavailability, and metabolism The functional importance of melatonin receptors and their role in mediating the therapeutic effectiveness of melatonin in cancer Melatonin’s effect on the regulation of blood pressure, sleep, and circadian rhythms The cardioprotective role of melatonin The neuroprotective role in glaucoma, Alzheimer’s disease, Parkinson’s disease, and neurodegenerative diseases Use as a therapeutic agent for treating epilepsy and degenerative discs Treatment for obesity, diabetes mellitus, and other metabolic disorders Protective role in peri-natal hypoxic-ischemia The contributors also examine the discovery of a number of melatonergic agonists, their potential role as antioxidants, and their therapeutic applications in treating glaucoma, Parkinson’s disease, Alzheimer’s disease, primary insomnia, and psychiatric disorders. Opening new vistas in our understanding of etiology, pharmacotherapy, and treatment, the book is a significant milestone in our knowledge about advances in melatonin’s physiology and its therapeutic application in a number of disorders.
| Author | : C. Bartsch |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 979 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 364259512X |
The link between the pineal gland and cancer is a rapidly emerging research field due to promising experimental and clinical trials with melatonin. The pineal gland acts as a transducer of environmental light to regulate rhythmic processes, including reproductive function in seasonally breeding animals and the entrainment of circadian rhythms, such as the sleep-wake cycle, in man. This book elucidates the physiological significance of the pineal gland and surveys phenomena and mechanisms of pineal - tumor interaction at the neuroendocrine, neuroimmune, neural, and molecular levels. Yet unidentified low-molecular-weight pineal substances with tumor-inhibiting capacity, a possible involvement of melatonin in electromagnetic field effects on cancer, and the oncotherapeutic potential of melatonin are also addressed. The encouraging results should incite further research to elucidate the exact nature of the link between the pineal gland and cancer for the benefit of patients.
