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Traversing the Valley of Death

Traversing the Valley of Death
Author: Stephen K. Markham
Publisher:
Total Pages:
Release: 2014-12-20
Genre:
ISBN: 9780990985303

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Traversing the Valley of Death

Traversing the Valley of Death
Author: Stephen K Markham Ph D
Publisher:
Total Pages: 216
Release: 2014-12-15
Genre: Business planning
ISBN: 9780990985310

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Traversing the Valley of Death is for managers with responsibility to grow revenue and market share or open new markets and lines of business. The process contained in this book provides a complete system to create new value starting with early needs assessment and continuing through detailed business planning and organizational adoption. This is an advanced book; it assumes managers are well initiated into their markets and company capabilities.


Only the Paranoid Survive

Only the Paranoid Survive
Author: Andrew S. Grove
Publisher: Currency
Total Pages: 242
Release: 1999-03-16
Genre: Business & Economics
ISBN: 0385483821

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Andy Grove, founder and former CEO of Intel shares his strategy for success as he takes the reader deep inside the workings of a major company in Only the Paranoid Survive. Under Andy Grove's leadership, Intel became the world's largest chip maker and one of the most admired companies in the world. In Only the Paranoid Survive, Grove reveals his strategy for measuring the nightmare moment every leader dreads--when massive change occurs and a company must, virtually overnight, adapt or fall by the wayside--in a new way. Grove calls such a moment a Strategic Inflection Point, which can be set off by almost anything: mega-competition, a change in regulations, or a seemingly modest change in technology. When a Strategic Inflection Point hits, the ordinary rules of business go out the window. Yet, managed right, a Strategic Inflection Point can be an opportunity to win in the marketplace and emerge stronger than ever. Grove underscores his message by examining his own record of success and failure, including how he navigated the events of the Pentium flaw, which threatened Intel's reputation in 1994, and how he has dealt with the explosions in growth of the Internet. The work of a lifetime, Only the Paranoid Survive is a classic of managerial and leadership skills.


Cell Press Reviews: Cancer Therapeutics

Cell Press Reviews: Cancer Therapeutics
Author: Cell Press
Publisher: Elsevier
Total Pages: 323
Release: 2013-12-10
Genre: Medical
ISBN: 0127999175

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Cell Press Reviews: Cancer Therapeutics informs, inspires, and connects cancer researchers at all stages in their careers with timely, comprehensive reviews written by leaders in the field and curated by Cell Press editors. The publicatio offers a broad view of some of the most compelling topics in cancer therapeutics including: Genetic approaches for personal oncology Targeting epigenetic dysregulation and protein interaction networks Vaccines and antibodies in cancer immunotherapy Tumor heterogeneity and chemotherapy resistance Tumor associated macrophages in anticancer treatment Contributions come from leading voices in the field, including: - Daniel A. Haber, Director of Massachusetts General Hospital Cancer Center and Professor at Harvard Medical School - Tony Kouzarides, Professor at the University of Cambridge, Deputy Director of the Wellcome Trust/Cancer Research UK Gurdon Institute, and a founder of the cancer drug discovery company Chroma Therapeutics - Charles L. Sawyers, Chair of the Human Oncology and Pathogenesis Program at Memorial Sloan Kettering Cancer Center, President of the American Association for Cancer Research, member of the presidentially appointed National Cancer Advisory Board, and recipient of the 2013 Breakthrough Prize in Life Sciences Cell Press Reviews: Cancer Therapeutics is part of the Cell Press Reviews series, which features reviews published in Cell Press primary research and Trends reviews journals. Provides timely, comprehensive articles on a wide range of topics in cancer therapeutics Offers insight from experts on genetic, molecular, and cellular aspects of cancer therapy Features reviews on basic science advances translated into drug discovery and therapeutic approaches Includes articles originally published in Cell, Cancer Cell, Trends in Genetics, Trends in Molecular Medicine, and Trends in Pharmacological Sciences


Seemed Like a Good Idea

Seemed Like a Good Idea
Author: Mark Pauly
Publisher: Cambridge University Press
Total Pages: 425
Release: 2022-07-28
Genre: Business & Economics
ISBN: 1009019112

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Consumers, public officials, and even managers of health care and insurance are unhappy about care quality, access, and costs. This book shows that is because efforts to do something about these problems often rely on hope or conjecture, not rigorous evidence of effectiveness. In this book, experts in the field separate the speculative from the proven with regard to how care is rendered, how patients can be in control, how providers should be paid, and how disparities can be reduced – and they also identify the issues for which evidence is currently missing. It provides an antidote to frustration and a clear-eyed guide for forward progress, helping health care and insurance innovators make better decisions on deciding whether to go ahead now based on current evidence, to seek and wait for additional evidence, or to move on to different ideas. It will be useful to practitioners in hospital systems, medical groups, and insurance organizations and can also be used in executive and MBA teaching.


Achieving Proof of Concept in Drug Discovery and Development

Achieving Proof of Concept in Drug Discovery and Development
Author: Helen Yu
Publisher: Edward Elgar Publishing
Total Pages: 304
Release: 2016-11-25
Genre:
ISBN: 1785369377

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One of the major shortcomings of the current drug discovery and development process is the inability to bridge the gap between early stage discoveries and pre-clinical research in order to advance innovations beyond the discovery phase. This book examines a drug discovery and development model, where the respective expertise of academia and industry are brought together to take promising discoveries through to proof of concept, providing a means to de-risk the drug discovery and development process.


The Culture of Hope Founded on Faith

The Culture of Hope Founded on Faith
Author: Susan Merritt PhD
Publisher: WestBow Press
Total Pages: 145
Release: 2017-05-04
Genre: Religion
ISBN: 1512784230

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When Dan Merritt was diagnosed with a rare cancer called mantle cell lymphoma, he and his wife, Susan, went to God and asked to see the fulfillment of the great and precious promises that are guaranteed in 2 Peter 1:3–4. As a result, through the losses and mourning that come with a catastrophic episode like this, they found themselves living in the culture of hope founded on faith. Follow the story of their journey into their new mission field of medical offices and hospital rooms. Learn how God carried them all the way to healing and gave them a brand new understanding of Him and His promises. Find out how you can follow God and live in the culture of hope even when your life turns 180 degrees from what you expected it to be.


Green Infrastructure Finance

Green Infrastructure Finance
Author: Aldo Baietti
Publisher: World Bank Publications
Total Pages: 265
Release: 2012-04-18
Genre: Business & Economics
ISBN: 0821394894

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This report is a structured compendium of leading initiatives and activities put forward to accelerate private investment flows in green growth. It summarizes current investment challenges of green projects as well as proposed solutions, financing schemes and initiatives that have set the stage for scaling up green infrastructure investments.


Beyond Smoke and Mirrors

Beyond Smoke and Mirrors
Author: Burton Richter
Publisher: Cambridge University Press
Total Pages: 244
Release: 2010-04-12
Genre: Science
ISBN: 1139486721

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Global climate change is one of the most important issues humanity faces today. This book assesses the sensible, senseless and biased proposals for averting the potentially disastrous consequences of global warming, allowing the reader to draw their own conclusions on switching to more sustainable energy provision. Burton Richter is a Nobel Prize-winning scientist who has served on many US and international review committees on climate change and energy issues. He provides a concise overview of our knowledge and uncertainties within climate change science , discusses current energy demand and supply patterns, and the energy options available to cut emissions of greenhouse gases. Written in non-technical language, this book presents a balanced view of options for moving from our heavy reliance on fossil fuels into a much more sustainable energy system, and is accessible to a wide range of readers without scientific backgrounds - students, policymakers, and the concerned citizen.