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Toxicology for the Health and Pharmaceutical Sciences

Toxicology for the Health and Pharmaceutical Sciences
Author: Antonio Peña-Fernández
Publisher:
Total Pages:
Release: 2021-09
Genre: Chemicals
ISBN: 9781032100227

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"There is an increasing need for knowledge of toxicology to safeguard the use of chemicals in industry, public and private sectors. The study of toxicology is becoming increasingly relevant in human health sciences, as future health and clinical professionals will be pivotal to address and manage emerging chemical threats and hazards related to modern anthropogenic activities and technological development. Comprising a series of chapters from leading toxicology, pharmacy and public health academics and experts across Europe, the United States and beyond, Toxicology for the Health and Pharmaceutical Sciences provides a concise yet comprehensive volume that can be used as a relevant textbook on toxicology for the clinical, healthcare, educational and professional sectors. This book covers the fundamentals and recent developments in toxicology, to respond to local and global chemical, pharmaceutical and environmental threats. Thus, this volume has chapters specifically designed to support the understanding of the most current, toxicology-related subjects for any undergraduate/postgraduate health programmes, as well as aiding with the delivery of continuing professional development training on up-to-date topics in toxicology for current practicing health professionals wishing to improve their background knowledge in toxicology. The book is also vital reading, and reference for policy makers, and others that influence, and decide regulations that have an impact on the environment, and human health"--


Clinical Toxicology

Clinical Toxicology
Author: Frank A. Barile
Publisher: CRC Press
Total Pages: 474
Release: 2003-12-17
Genre: Medical
ISBN: 0849315824

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Concise and authoritative, Clinical Toxicology: Principles and Mechanisms examines the complex interactions associated with clinical toxicological events and chemical exposure or drug administration. The author places special emphasis on signs and symptoms of diseases and pathology caused by toxins and clinical drugs. He covers contemporary issues in clinical toxicology, such as biological and chemical toxins, changes in protocols for managing toxic ingestions, new antidotes, changes in particular treatments, and pharmacology and toxicology of herbal products. After introducing the fundamental principles of toxicology, the book presents the toxicity of therapeutic and non-therapeutic agents in separate sections. Most chapters start with a basic review of the general physiology and pharmacology principles necessary for understanding the underlying mechanisms of toxicity. The book includes numerous drawings, figures, and tables that improve understanding of the mechanisms involved in chemical exposure. It covers widely distributed chemical agents and currently used therapeutic drugs that possess hazardous effects either as principle mechanisms of action or as untoward adverse drug reactions. A reader-friendly exposition of clinical toxicology, Clinical Toxicology: Principles and Mechanisms can be used as a stand-alone text or a professional reference.


Barile’s Clinical Toxicology

Barile’s Clinical Toxicology
Author: Frank A. Barile
Publisher: CRC Press
Total Pages: 530
Release: 2019-04-24
Genre: Medical
ISBN: 0429532016

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As with the two previous editions, Barile’s Clinical Toxicology: Principles and Mechanisms, Third edition, examines the complex interactions associated with clinical toxicological events as a result of therapeutic drug administration or chemical exposure. With special emphasis placed on signs and symptoms of diseases and pathology caused by toxins and clinical drugs, the new edition, examines the complex interactions associated with clinical toxicological events as a result of therapeutic drug administration or chemical exposure. The new edition presents the latest, up-to-date protocols for managing various toxic ingestions, and the antidotes and treatments associated with their pathology. In addition, the effect of toxins on a limited number of body systems and drug-induced adverse drug reactions are also covered. KEY FEATURES • Discusses source of the drug or chemical, pharmacological and toxicological mechanisms of action, detection, identification, and treatment • Examines the complex interactions associated with clinical toxicological events • Emphasizes the signs and symptoms of diseases and pathology caused by toxins and clinical drugs • Covers effect of toxins on body systems and drug-induced adverse reactions • Offers a unique perspective for toxicology, pharmacology, pharmacy and health professions students The target audience for this book is undergraduate and graduate toxicology students, clinical pharmacy (Pharm.D.) students, emergency medical personnel, regulatory agencies, and other related health science professionals. It satisfies an essential need for a concise yet detailed authoritative, fundamental text addressing the current principles of clinical toxicology.


Public Health and Toxicology Issues in Drug Research, Volume 2

Public Health and Toxicology Issues in Drug Research, Volume 2
Author: Rakesh Kumar Tekade
Publisher: Elsevier
Total Pages: 854
Release: 2024-04-05
Genre: Medical
ISBN: 0443158436

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Toxicodynamics in Drug Research, Volume 2: Public Health and Toxicology Issues examines the implications of public health issues and the impact of pharmaceuticals, chemical and food toxicants, dietary phytochemicals, and medical treatments on human health. Volume 2: Public Health and Toxicology Issues in Drug Research: Toxicity and Toxicodynamics covers topics on pharmacokinetics and toxicokinetics such as population pharmacokinetics/toxicokinetics, the design of toxicokinetic studies, and the use of toxicokinetic data in preclinical safety assessments. The book investigates the health effect caused by the bioaccumulation of pharmaceutical and personal care products and the impact of drug-induced toxicity on different systems of the body. It discusses the mechanistic pathways of food toxicants and illustrates the molecular mechanisms of the chemopreventive role of dietary phytochemicals. It also delves into the toxic effects of medical treatments and materials. Ethical, legal, societal, and professional issues in toxicology round off the coverage providing a valuable resource to interested in learning more about the health impact and public health issues related to the toxicity of pharmaceuticals, dietary supplements, personal care products, and medical treatments. Discusses the impact of pharmaceuticals, food, and chemical toxicants on human health Examines the toxic effects of medical treatments, clinical administrations, and materials Explores public health issues around drug safety and toxicology


Information Resources in Toxicology, Volume 2: The Global Arena

Information Resources in Toxicology, Volume 2: The Global Arena
Author: Steve Gilbert
Publisher: Academic Press
Total Pages: 809
Release: 2020-05-15
Genre: Medical
ISBN: 0128216123

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This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools. Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field. The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children’s environmental health. Opens with an overview of the international toxicology scene, organizations and activities involved with both the science and regulatory framework, and a specific look at the European Union’s efforts Offers an extensive collection of chapters covering over 40 countries and their toxicological infrastructure which includes listings of major books and journals, organizations, professional societies, universities, poison control centers, legislation, and online databases Provides the Second Edition of the International Union of Pure and Applied Chemistry’s Glossary of Terms Used in Toxicology, a carefully constructed and peer reviewed collation of critical terms in the science Concludes with a potpourri of quotes concerning toxicology and their use in the arts and popular culture Paired with Volume One, which offers chapters on a host of toxicology sub-disciplines, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over120 chapters contributions by experts and leaders in the field


Toxicology in Current Science

Toxicology in Current Science
Author: Dr. Debasish Pradhan, Dr. Gitanjali Tripathy, Dr. Ashok Ku Pattnaik, Dr. Bishnu Charan Pradhan, Mr. Shaktiprasad Pradhan, Bandana Behera
Publisher: Notion Press
Total Pages: 364
Release: 2018-04-18
Genre: Science
ISBN: 1642490717

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Toxicology begins from basic research investigations on the mechanism of action of toxins through the development and interpretation of standard tests characterizing the toxic properties of agents. Toxicology provides important tools for both medicine and epidemiology in understanding aetiology and in providing information as to the plausibility of observed associations between exposures, including occupations, and disease. Toxicology can be divided into various disciplines, such as clinical, forensic, investigative and regulatory toxicology; toxicology can be considered by target organ system or process, such as immunotoxicology or genetic toxicology; toxicology can be presented in functional terms, such as research, testing and risk assessment. Today, toxicology has become an important element in environmental and occupational health. As part of prevention strategies, toxicology is invaluable, since it is the source of information on potential hazards in the absence of widespread human exposures. Toxicological screening are also widely used by industry, academic in product development, to provide information useful in the design of specific molecules or product formulations.


An Introduction to Toxicology

An Introduction to Toxicology
Author: Philip C. Burcham
Publisher: Springer Science & Business Media
Total Pages: 338
Release: 2013-11-19
Genre: Medical
ISBN: 144715553X

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This book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest is devoted to chemicals that undergo conversion to toxic metabolites that induce toxic effects as diverse as cancer, birth defects and organ injury. The molecular consequences accompanying damage to cellular DNA and proteins is explored together with the relevance of toxicological paradigms to human diseases caused by alcohol and tobacco. The discipline of toxicology has developed rapidly since the thalidomide disaster in the 1960’s as scientists worldwide seek to understand the adverse health effects of human medicines, environmental pollutants, consumer chemicals and industrial reagents. An Introduction to Toxicology is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that “unpack” the concepts being discussed in the text. ​


Translational Toxicology

Translational Toxicology
Author: Claude L. Hughes
Publisher: Humana Press
Total Pages: 384
Release: 2016-03-23
Genre: Medical
ISBN: 331927449X

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Bringing together a distinguished interdisciplinary team of contributors, this volume provides a comprehensive exploration of translational toxicology—a systematic approach to developing therapeutic interventions that can protect against, mitigate, or reverse the effects of exposures. In particular, the book addresses modes of action and biomarkers, developmental risks of exposures, and potential translational toxicology therapeutics. The result is a compelling application of developmental toxicology in a new therapeutic discipline that is destined to become part of standard medical practice. Translational Toxicology: Defining a New Therapeutic Discipline is an essential text for regulatory authorities, scientists, and physicians who are concerned with environmental exposures, public health, nutrition, and pharmaceutical research and development. Basic science, epidemiological, and clinical investigators will also find this book a significant resource.


Pharmaceutical Toxicology

Pharmaceutical Toxicology
Author: Gerard J. Mulder
Publisher:
Total Pages: 257
Release: 2006
Genre:
ISBN: 9783769242010

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Barile's Clinical Toxicology, Third Edition

Barile's Clinical Toxicology, Third Edition
Author: Frank A. Barile
Publisher: CRC Press
Total Pages: 584
Release: 2019-05-13
Genre:
ISBN: 9781498765305

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As with the two previous editions, Barile's Clinical Toxicology: Principles and Mechanisms, Third edition, examines the complex interactions associated with clinical toxicological events as a result of therapeutic drug administration or chemical exposure. With special emphasis placed on signs and symptoms of diseases and pathology caused by toxins and clinical drugs, the new edition, examines the complex interactions associated with clinical toxicological events as a result of therapeutic drug administration or chemical exposure. The new edition presents the latest, up-to-date protocols for managing various toxic ingestions, and the antidotes and treatments associated with their pathology. In addition, the effect of toxins on a limited number of body systems and drug-induced adverse drug reactions are also covered. KEY FEATURES * Discusses source of the drug or chemical, pharmacological and toxicological mechanisms of action, detection, identification, and treatment * Examines the complex interactions associated with clinical toxicological events * Emphasizes the signs and symptoms of diseases and pathology caused by toxins and clinical drugs * Covers effect of toxins on body systems and drug-induced adverse reactions * Offers a unique perspective for toxicology, pharmacology, pharmacy and health professions students The target audience for this book is undergraduate and graduate toxicology students, clinical pharmacy (Pharm.D.) students, emergency medical personnel, regulatory agencies, and other related health science professionals. It satisfies an essential need for a concise yet detailed authoritative, fundamental text addressing the current principles of clinical toxicology. logical mechanisms of action, detection, identification, and treatment * Examines the complex interactions associated with clinical toxicological events * Emphasizes the signs and symptoms of diseases and pathology caused by toxins and clinical drugs * Covers effect of toxins on body systems and drug-induced adverse reactions * Offers a unique perspective for toxicology, pharmacology, pharmacy and health professions students The target audience for this book is undergraduate and graduate toxicology students, clinical pharmacy (Pharm.D.) students, emergency medical personnel, regulatory agencies, and other related health science professionals. It satisfies an essential need for a concise yet detailed authoritative, fundamental text addressing the current principles of clinical toxicology.