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The Shotgun Method

The Shotgun Method
Author: Mogens Herman Hansen
Publisher: University of Missouri Press
Total Pages: 153
Release: 2006
Genre: History
ISBN: 0826265480

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"Reflecting the innovative work of the Copenhagen Polis Centre's 2004 inventory of Archaic and Classical Greek city-states, Hansen's "shotgun method" for reconstructing and estimating the overall size and local distribution of the Greek population challenges the long-standing opinion that the majority of ancient Greeks lived a rural, subsistent life"--Provided by publisher.


Robert Churchill's Game Shooting

Robert Churchill's Game Shooting
Author: Robert Churchill
Publisher: Down East Books
Total Pages: 252
Release: 1990-01-01
Genre: Sports & Recreation
ISBN: 9780924357114

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Robert Churchill wrote the definitive book on instinctive wingshooting for game birds and sporting clays. It quickly became a classic in the field. Friend and collaborator Macdonald Hastings, himself a renowned shooting coach, twice revised and updated Churchill's book.


Move, Mount, Shoot

Move, Mount, Shoot
Author: John Bidwell
Publisher: Crowood Press (UK)
Total Pages: 0
Release: 1990
Genre: Trapshooting
ISBN: 9781852233006

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Sporting clay shooters are constantly striving for consistency. Move, Mount, Shoot describes the maintained lead method, an easily learned technique which will help both novice and expert alike achieve spectacular results. The book also examines the importance of mental preparation, . and includes advice on choosing a gun and equipment. Move, Mount, Shoot is the only comprehensive manual of this winning technique.


Automated DNA Sequencing and Analysis

Automated DNA Sequencing and Analysis
Author: Mark D. Adams
Publisher: Elsevier
Total Pages: 389
Release: 2012-12-02
Genre: Science
ISBN: 0080926398

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A timely book for DNA researchers, Automated DNA Sequencing and Analysis reviews and assesses the state of the art of automated DNA sequence analysis-from the construction of clone libraries to the developmentof laboratory and community databases. It presents the methodologies and strategies of automated DNA sequence analysis in a way that allows them to be compared and contrasted. By taking a broad view of the process of automated sequence analysis, the present volume bridges the gap between the protocols supplied with instrument and reaction kits and the finalized data presented in the research literature. It will be an invaluable aid to both small laboratories that are interested in taking maximum advantageof automated sequence resources and to groups pursuing large-scale cDNA and genomic sequencing projects. The field of automation in DAN sequencing and analysis is rapidly moving, this book fulfils those needs, reviews the history of the art and provides pointers to future development.


Mass Spectrometry-Based Chemical Proteomics

Mass Spectrometry-Based Chemical Proteomics
Author: W. Andy Tao
Publisher: John Wiley & Sons
Total Pages: 448
Release: 2019-07-10
Genre: Science
ISBN: 1118970217

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PROVIDES STRATEGIES AND CONCEPTS FOR UNDERSTANDING CHEMICAL PROTEOMICS, AND ANALYZING PROTEIN FUNCTIONS, MODIFICATIONS, AND INTERACTIONS—EMPHASIZING MASS SPECTROMETRY THROUGHOUT Covering mass spectrometry for chemical proteomics, this book helps readers understand analytical strategies behind protein functions, their modifications and interactions, and applications in drug discovery. It provides a basic overview and presents concepts in chemical proteomics through three angles: Strategies, Technical Advances, and Applications. Chapters cover those many technical advances and applications in drug discovery, from target identification to validation and potential treatments. The first section of Mass Spectrometry-Based Chemical Proteomics starts by reviewing basic methods and recent advances in mass spectrometry for proteomics, including shotgun proteomics, quantitative proteomics, and data analyses. The next section covers a variety of techniques and strategies coupling chemical probes to MS-based proteomics to provide functional insights into the proteome. In the last section, it focuses on using chemical strategies to study protein post-translational modifications and high-order structures. Summarizes chemical proteomics, up-to-date concepts, analysis, and target validation Covers fundamentals and strategies, including the profiling of enzyme activities and protein-drug interactions Explains technical advances in the field and describes on shotgun proteomics, quantitative proteomics, and corresponding methods of software and database usage for proteomics Includes a wide variety of applications in drug discovery, from kinase inhibitors and intracellular drug targets to the chemoproteomics analysis of natural products Addresses an important tool in small molecule drug discovery, appealing to both academia and the pharmaceutical industry Mass Spectrometry-Based Chemical Proteomics is an excellent source of information for readers in both academia and industry in a variety of fields, including pharmaceutical sciences, drug discovery, molecular biology, bioinformatics, and analytical sciences.


The Genome War

The Genome War
Author: James Shreeve
Publisher: Ballantine Books
Total Pages: 418
Release: 2007-12-18
Genre: Science
ISBN: 0307417069

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The long-awaited story of the science, the business, the politics, the intrigue behind the scenes of the most ferocious competition in the history of modern science—the race to map the human genome. On May 10, 1998, biologist Craig Venter, director of the Institute for Genomic Research, announced that he was forming a private company that within three years would unravel the complete genetic code of human life—seven years before the projected finish of the U.S. government’s Human Genome Project. Venter hoped that by decoding the genome ahead of schedule, he would speed up the pace of biomedical research and save the lives of thousands of people. He also hoped to become very famous and very rich. Calling his company Celera (from the Latin for “speed”), he assembled a small group of scientists in an empty building in Rockville, Maryland, and set to work. At the same time, the leaders of the government program, under the direction of Francis Collins, head of the National Human Genome Research Institute at the National Institutes of Health, began to mobilize an unexpectedly unified effort to beat Venter to the prize—knowledge that had the potential to revolutionize medicine and society. The stage was set for one of the most thrilling—and important—dramas in the history of science. The Genome War is the definitive account of that drama—the race for the greatest prize biology has had to offer, told by a writer with exclusive access to Venter’s operation from start to finish. It is also the story of how one man’s ambition created a scientific Camelot where, for a moment, it seemed that the competing interests of pure science and commercial profit might be gloriously reconciled—and the national repercussions that resulted when that dream went awry.


Shotgunning in the Automatic Mind

Shotgunning in the Automatic Mind
Author: Warren Watson
Publisher:
Total Pages: 227
Release: 2019-03-18
Genre: Firearms
ISBN: 9780692092255

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Instructional book on shotgun skills for sporting clays and fieldcraft. Provides a better understanding for anyone to improve their performance and skills with a shotgun.


Bacterial Artificial Chromosomes

Bacterial Artificial Chromosomes
Author: Shaying Zhao
Publisher:
Total Pages: 0
Release: 2004
Genre: Bacterial artificial chromosomes
ISBN:

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Outsmart Your Genes

Outsmart Your Genes
Author: Brandon Colby MD
Publisher: Penguin
Total Pages: 327
Release: 2010-04-06
Genre: Health & Fitness
ISBN: 1101186771

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Predictive medicine is the most exciting—and potentially groundbreaking—medical development in decades. Written by Brandon Colby, MD, a leader in the fields of predictive medicine and genetic testing, Outsmart Your Genes will empower you, the reader, with a clear understanding of exactly what predictive medicine entails and how it can be used today to protect your health as well as the health of those you love. Written in straightforward, nontechnical language, Outsmart Your Genes enables everyone, even those without any background in genetics or medicine, to understand the benefits of predictive medicine. Separating myth from fact and answering all the tough questions, Outsmart Your Genes clearly explains: How the revolutionary new medical specialty called predictive medicine analyzes your genes and provides you with clear solutions to protect your health and wellbeing. What the process will entail and how simple it is. For example, the process doesn’t even require blood or use needles – instead, all that’s needed in order to run the analysis is a small amount of your saliva. What your genes can reveal about your overall health and how we can use that information to provide you with a genetically tailored plan for preventing cancer, Alzheimer's, heart disease, obesity, and many other conditions. As opposed to just generalities, specific examples are given so that you’ll know exactly how medicine will improve your life. The many ways in-which learning about your genes can help you formulate a genetically tailored nutrition and athletic plan that may help you shed those extra pounds and stay trim and fit. How predictive medicine can help both prospective and current parents protect their children against SIDS and also help minimize the impact of and most effectively treat many other childhood diseases such as autism, asthma, dyslexia, obesity, and diabetes. Why analyzing your children’s genes may provide the best chance they have to fight against diseases that may not affect them until later in life, including Alzheimer’s, many forms of cancer (such as breast cancer and skin cancer), multiple sclerosis, and even hearing loss. How groundbreaking advancements in the fields of genetic analysis, including predictive medicine panels and disease matrix technology, allow you and your physician to avoid information overload and focus only on the information most relevant to you. The important concepts you need to understand before speaking with a doctor. The top five questions you need to ask in order to assess: The credibility of the laboratory doing the testing. The types of diseases included in the test. How thoroughly the test actually evaluates your risk for each of the diseases. Whether the information is provided in a way that makes it actionable. Whether the results will be delivered in a format that is straightforward and easy to understand.


Shotgun Proteomics

Shotgun Proteomics
Author: Daniel Martins-de-Souza
Publisher: Humana Press
Total Pages: 492
Release: 2017-04-30
Genre: Science
ISBN: 9781493946952

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Shotgun Proteomics: Methods and Protocols serves as a vital collection of protocols through which thousands of proteins can be simultaneously identified, quantified and characterized in a high throughput manner. Beginning with the history of proteomics centered on the vital role of mass spectrometry in its development, this detailed volume continues with chapters on sample pre-fractionation, in vivo and in vitro stable isotope labeling, label-free proteomics, informatics, protein-protein interactions, targeted proteomics and post-translational modifications. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Practical and comprehensive, Shotgun Proteomics: Methods and Protocols is an ideal and up-to-date guide for researchers seeking to understand the proteome of any given species.