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| Author | : MaryEllen Carlile |
| Publisher | : |
| Total Pages | : 218 |
| Release | : 2006 |
| Genre | : Atherosclerosis |
| ISBN | : |
| Author | : Edward Bittar |
| Publisher | : Elsevier Science |
| Total Pages | : 264 |
| Release | : 2005-07-20 |
| Genre | : Science |
| ISBN | : 9780444515001 |
Caveolae (latin for little caves) are small structures found at the surface of cells. They are responsible for the regulation of important metabolic pathway. As a consequence, they may play a critical role in several human diseases such as atherosclerosis, cancer, diabetes, and muscular dystrophies. This book analyzes the role and function of caveolae in these aspects and serves as the first textbook currently available on caveolae/caveolin.
| Author | : Christopher J. Fielding |
| Publisher | : John Wiley & Sons |
| Total Pages | : 294 |
| Release | : 2006-12-13 |
| Genre | : Science |
| ISBN | : 3527607501 |
This keenly awaited first overview of the field represents a complete guide to the structure and function of the most important mammalian cell membrane organelles. Filling a huge gap in the primary literature, this book is the first to cover the subject in detail. Following an introduction by Kai Simons, the discoverer of lipid rafts and the most prominent scientist in the field, chapters include: Historical background Distinct structures and functions Structural basis Signaling Viral entry and virion budding Cholesterol transport Caveolins Lipid shells Cell polarity and intracellular trafficking Cancer cells Of prime importance to molecular and cell biologists, biochemists, membrane scientists, cancer researchers, and virologists.
| Author | : |
| Publisher | : Elsevier |
| Total Pages | : 475 |
| Release | : 2003-05-03 |
| Genre | : Science |
| ISBN | : 0080490883 |
Cell Surface Proteases provides a comprehensive overview of these important enzymes that catalyze the hydrolysis of a protein as it degrades to a simpler substance. In the 1990s, an explosion of new discoveries shed light on the role of cell surface proteases and extended it beyond degradation of extracellular matrix components to include its influence on growth factors, cell signaling, and other cellular events. This volume unites the scientific literature from across disciplines and teases out unified themes of interactions between cell surface proteases and interconnecting cell surface-related systems -- including integrins and other adhesion molecules. Scientists and students involved in developmental biology, cell biology and disease processes will find this an indispensable resource. * Provides an overview of the entire field of cell surface proteases in a single volume* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine * A thematic volume in the longest-running forum for contemporary issues in developmental biology with over 30 years of coverage
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 393 |
| Release | : 2015-06-08 |
| Genre | : Science |
| ISBN | : 0128033274 |
Current Topics in Membranes is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. This volume offers an up to date presentation of current knowledge in the field of Lipid Domains. Written by leading experts Contains original material, both textual and illustrative, that should become a very relevant reference material The material is presented in a very comprehensive manner Both researchers in the field and general readers should find relevant and up-to-date information
| Author | : Cai Huang |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 482 |
| Release | : 2012-09-06 |
| Genre | : Medical |
| ISBN | : 9535107372 |
15 chapters on protein phosphorylation and human health written by expert scientists. Covers most important research hot points, such as Akt, AMPK and mTOR. Bridges the basic protein phosphorylation pathways with human health and diseases. Detailed and comprehensive text with excellent figure illustration.
| Author | : Arnold von Eckardstein |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2015-01-13 |
| Genre | : Medical |
| ISBN | : 9783319096643 |
In this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing attempts of therapeutic exploitation. The book is of interest to researchers in academia and industry focusing on lipoprotein metabolism, cardiovascular diseases and immunology as well as clinical pharmacologists, cardiologists, diabetologists, nephrologists and other clinicians interested in metabolic or inflammatory diseases.
| Author | : Kjell Fuxe |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 577 |
| Release | : 2013-03-13 |
| Genre | : Computers |
| ISBN | : 1468454153 |
| Author | : Stavros J. Baloyannis |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2021 |
| Genre | : Brain |
| ISBN | : 9781839680984 |
Cerebral and Cerebellar Cortex - Interaction and Dynamics in Health and Disease discusses several important issues of cerebro-cerebellar collaboration and interactions. The morphological and functional study of the cerebral and cerebellar cortices and their interaction has considerable value for interpreting the clinical phenomenology of cortical degenerations in the initial stage of the disease. In addition, the analysis of cerebro-cerebellar interactions strongly supports the concept of the close functional unity and harmonization of the brain and the cerebellum, underlining the important role that the cerebellar cortex plays in the performance of higher mental faculties, creativity, emotional processes, and homeostatic equilibrium of the human body.
| Author | : Nathalie Vergnolle |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 318 |
| Release | : 2011-08-03 |
| Genre | : Medical |
| ISBN | : 3034801572 |
Proteases are everywhere from prokaryotes to eukaryotes, from virus to bacteria and in all human tissues, playing a role in many biological functions. Among these functions, the inflammatory reaction is of particular interest. In inflamed tissues, proteases can have a microbial and/or host origin and are involved not only in tissue remodeling, but also in specific signaling to resident or inflammatory cells, thereby contributing to the innate immune response. This volume presents all advances in our knowledge of the role proteases and their inhibitors play in various diseases associated with inflammatory response. Mechanisms involved in protease signaling to cells are presented, and the different types of proteases that are present at inflammatory sites and their effects on the course of inflammation are discussed. Finally, the evidence for considering proteases and their receptors as potential molecular targets for therapeutic interventions in the treatment of inflammatory diseases is discussed in the context of specific organ inflammatory pathologies (the lung, gastrointestinal tract, skin, joints, etc.).
