The Role Of Hepatic Sinusoidal Cells In Liver Disease PDF Download

Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download The Role Of Hepatic Sinusoidal Cells In Liver Disease PDF full book. Access full book title The Role Of Hepatic Sinusoidal Cells In Liver Disease.

Liver Diseases and Hepatic Sinusoidal Cells

Liver Diseases and Hepatic Sinusoidal Cells
Author: Kyuichi Tanikawa
Publisher: Springer Science & Business Media
Total Pages: 547
Release: 2012-12-06
Genre: Medical
ISBN: 4431679359
GET BOOK

Download Liver Diseases and Hepatic Sinusoidal Cells Book in PDF, ePub and Kindle

Hepatic sinusoidal cells such as sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, and pit cells play an important role in hemodynamic and metabolic function and are involved in various liver diseases. The frequent involvement of sinusoidal cells in pathologic conditions is explained by the diverse actions of those cells, an understanding of which is essential to clinicians. Generously illustrated, this volume presents results of recent studies on hepatic sinusoidal cells in liver diseases, with an introduction to the structure and function of the various types of sinusoidal cells. The in-depth focus of the book is on the role of hepatic sinusoidal cells in relation to liver injury and regeneration, hepatic sinusoidal microcirculation, alcoholic liver diseases, hepatic fibrosis, liver tumor, liver transplantation, cholestasis, and congenital lipidosis, thus providing a valuable reference source for practitioners and researchers.

Sinusoidal Cells in Liver Diseases

Sinusoidal Cells in Liver Diseases
Author: Jordi Gracia-Sancho
Publisher: Elsevier
Total Pages: 564
Release: 2024-04-19
Genre: Science
ISBN: 0323952631
GET BOOK

Download Sinusoidal Cells in Liver Diseases Book in PDF, ePub and Kindle

Sinusoidal Cells in Liver Diseases: Role in their Pathophysiology, Diagnosis, and Treatment provides a state-of-the-art review on recent advances surrounding the role of liver sinusoidal cells (LSECs, HSCs, macrophages, and other non-parenchymal cells) in acute and chronic liver diseases. Coverage emphasizes disease pathophysiology, novel mechanisms, unmet clinical questions, development of biomarkers and treatment opportunities. By focusing on the role of sinusoidal cells in human liver diseases, this reference provides a comprehensive overview of the role of sinusoidal cells in acute and chronic liver diseases, in its pathophysiology and mechanisms, and in the development of novel biomarkers and new therapeutics. Cells of the liver vasculature play an essential role in the pathophysiology of acute and chronic liver diseases and are considered key therapeutic targets to treat most of human hepatopathies. Coverage in this reference includes the phenotypic changes occurring in liver vascular cells and how cells contribute to the development of microcirculatory dysfunction, fibrosis, inflammation, and liver failure. Provides a comprehensive update on the role of sinusoidal cells in acute and chronic liver diseases Covers our current understanding of the role of sinusoidal cells as therapeutic targets to improve liver diseases Presents the latest research in the development of novel biomarkers of liver diseases that derive from sinusoidal cells

Stellate Cells in Health and Disease

Stellate Cells in Health and Disease
Author: Chandrashekhar Gandhi
Publisher: Academic Press
Total Pages: 335
Release: 2015-04-10
Genre: Science
ISBN: 0128005440
GET BOOK

Download Stellate Cells in Health and Disease Book in PDF, ePub and Kindle

Stellate Cells in Health and Disease is a comprehensive reference providing the most up-to-date knowledge and perspectives on the function of stellate cells affecting the liver and other organs. The text presents comprehensive coverage of their already established role in hepatic fibrosis along with the newer emerging evidence for stellate cell participation in the liver cell (hepatocyte) survival and regeneration, hepatic immunobiology, transplant tolerance, and liver cancer. Chapters describe both animal and human research and the relevance of findings from animal research to human pathophysiology, and also contain sections on future directions which will be of special interest to basic and clinical researchers working on liver fibrosis, hepatic biology, and pathobiology. Presents coverage of the mechanisms of liver fibrosis with stellate cells as a target for therapy. Shows stellate cells as a major participant in hepatic immunobiology, including transplantation immunology. Key illustrations show the phenotypical changes in stellate cells in situ and tissue culture, their interactions with other cell types, signaling pathways and demonstrate the functions and roles of stellate cell in pathological processes.

The Liver

The Liver
Author: Irwin M. Arias
Publisher: John Wiley & Sons
Total Pages: 1156
Release: 2020-03-09
Genre: Medical
ISBN: 1119436826
GET BOOK

Download The Liver Book in PDF, ePub and Kindle

Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.

Hepatotoxicity

Hepatotoxicity
Author: Hyman J. Zimmerman
Publisher: Lippincott Williams & Wilkins
Total Pages: 848
Release: 1999
Genre: Medical
ISBN: 9780781719520
GET BOOK

Download Hepatotoxicity Book in PDF, ePub and Kindle

Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Obesity, Fatty Liver and Liver Cancer

Obesity, Fatty Liver and Liver Cancer
Author: Jun Yu
Publisher: Springer
Total Pages: 165
Release: 2018-06-28
Genre: Science
ISBN: 9811086842
GET BOOK

Download Obesity, Fatty Liver and Liver Cancer Book in PDF, ePub and Kindle

This volume covers a state-of-the-art illustration of recent discoveries concerning obesity-related fatty liver diseases and liver cancer. The contents are extensive and comprehensive. It brings important topics in the field all together under one umbrella, from epidemiology and etiology, molecular pathogenesis, cellular biology, epigenetics, immunology, microbiology, animal models to therapeutic approaches and treatments. All the book contributors are leading experts in the field. It will appeal to researchers, clinicians and graduate students in obesity, fatty liver diseases, GI/Liver cancer field. It may also yield benefits for pharmaceutical companies with regard to drug discovery.

Drug-Induced Liver Disease

Drug-Induced Liver Disease
Author: Neil Kaplowitz
Publisher: CRC Press
Total Pages: 790
Release: 2002-10-16
Genre: Medical
ISBN: 0203909127
GET BOOK

Download Drug-Induced Liver Disease Book in PDF, ePub and Kindle

Featuring more than 4100 references, Drug-Induced Liver Disease will be an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines.

Vascular Disorders of the Liver

Vascular Disorders of the Liver
Author: Dominique Valla
Publisher: Springer Nature
Total Pages: 376
Release: 2021-12-03
Genre: Medical
ISBN: 303082988X
GET BOOK

Download Vascular Disorders of the Liver Book in PDF, ePub and Kindle

This book provides a comprehensive account on individually rare, but collectively frequent diseases of the liver. In the first part, conditions such as hepatic vascular malformations, ischemic cholangiopathy, hepatic artery occlusion, sinusoidal conditions and Budd-Chiari syndrome are discussed among others. The second part examines the causes of vascular liver disease namely, coagulation disorders, neoplasm disorders, non-malignant blood disorders, systemic diseases and toxins, among others. The unique expertise of the authors, who are all members of the Vascular Liver Disease Disorders Group, an independent network of researchers with a common interest in Vascular Liver Diseases, are merged for an optimal pragmatic and individualized approach. This book is of interest to a broad range of experts, such as hepatologists, internists, radiologists and angiologists.