The Resolution And Use Of Chiral Auxiliaries In Asymmetric Synthesis PDF Download
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Author | : Robert Michael Lawrence |
Publisher | : |
Total Pages | : 450 |
Release | : 1988 |
Genre | : Chirality |
ISBN | : |
Download The resolution and use of chiral auxiliaries in asymmetric synthesis Book in PDF, ePub and Kindle
Author | : Alan Aitken |
Publisher | : CRC Press |
Total Pages | : 256 |
Release | : 1992-12-30 |
Genre | : Science |
ISBN | : 9780751401905 |
Download Asymmetric Synthesis Book in PDF, ePub and Kindle
Asymmetric synthesis is one of the most important areas of research and development in synthetic organic chemistry, and has wide-ranging industrial applications. This introduction to the subject covers chirality, nomenclature and analytical methods of resolution. The main body of the text describes the principal methods available to the organic chemist wishing to synthesize chiral compounds. Case studies are included, and reference sections allow access to the relevant review and research literature. This book is written for organic chemists at postgraduate and advanced undergraduate level.
Author | : Hélène Pellissier |
Publisher | : John Wiley & Sons |
Total Pages | : 610 |
Release | : 2017-03-28 |
Genre | : Science |
ISBN | : 3527802010 |
Download Asymmetric Synthesis of Three-Membered Rings Book in PDF, ePub and Kindle
The first handbook to focus on the asymmetric synthesis of different types of three-membered rings. The outstanding and experienced authors have an excellent international reputation and cover cyclopropanes, epoxides and aziridines as well as chiral oxaziridines in equal measure. To this end, they describe in detail different synthetic approaches starting with chiral substrates as well as the application of chiral metal- or organocatalysts. Furthermore, methods for the kinetic resolution of initially racemic products are treated alongside recent advances and novel developments in established techniques for the synthesis of three-membered rings. With its structured composition this is of high interest to scientists in methodological and natural product synthesis as well as those in industrial and pharmaceutical chemistry.
Author | : Robert E. Gawley |
Publisher | : Elsevier |
Total Pages | : 569 |
Release | : 2012-05-29 |
Genre | : Science |
ISBN | : 0080914136 |
Download Principles of Asymmetric Synthesis Book in PDF, ePub and Kindle
The world is chiral. Most of the molecules in it are chiral, and asymmetric synthesis is an important means by which enantiopure chiral molecules may be obtained for study and sale. Using examples from the literature of asymmetric synthesis, this book presents a detailed analysis of the factors that govern stereoselectivity in organic reactions. After an explanation of the basic physical-organic principles governing stereoselective reactions, the authors provide a detailed, annotated glossary of stereochemical terms. A chapter on "Practical Aspects of Asymmetric Synthesis" provides a critical overview of the most common methods for the preparation of enantiomerically pure compounds, techniques for analysis of stereoisomers using chromatographic, spectroscopic, and chiroptical methods. The authors then present an overview of the most important methods in contemporary asymmetric synthesis organized by reaction type. Thus, there are four chapters on carbon-carbon bond forming reactions, one chapter on reductions, and one on oxidations (carbon-oxygen and carbon-nitrogen bond forming reactions). This organization allows the reader to compare the leading methods for asymmetric synthesis in an appropriate context. A highlight of the book is the presentation and discussion of transition states at the current level of understanding, for important reaction types. In addition, extensive tables of examples are used to give the reader an appreciation for the scope of each reaction. Finally, leading references are provided to natural product synthesis that has been accomplished using a given reaction as a key step. Authoritative glossary to aid understanding of stereochemical terminology Explanations of the key factors influencing stereoselectivity with numerous examples, organized by reaction type A handy reference guide to the literature of asymmetric synthesis for practitioners in the field
Author | : G.R. Stephenson |
Publisher | : Springer Science & Business Media |
Total Pages | : 440 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 9400707975 |
Download Advanced Asymmetric Synthesis Book in PDF, ePub and Kindle
Asymmetric synthesis is one of the most critical strategic subjects in organic chemistry, and this book describes advanced techniques and their applications to the industrial and laboratory synthesis of important chiral molecules. The international team of highly respected authors provide rigorous and concise reviews of their areas of expertise.
Author | : David Ager |
Publisher | : CRC Press |
Total Pages | : 632 |
Release | : 2005-10-21 |
Genre | : Medical |
ISBN | : 1420027301 |
Download Handbook of Chiral Chemicals Book in PDF, ePub and Kindle
As pharmaceutical companies look to develop single enantiomers as drug candidates, chemists are increasingly faced with the problems associated with this subclass of organic synthesis. "The Handbook of Chiral Chemicals, Second Edition" highlights the problems associated with the production of chiral compounds on a commercial scale. The handbook fir
Author | : Jacek Wojaczynski |
Publisher | : John Wiley & Sons |
Total Pages | : 692 |
Release | : 2022-08-05 |
Genre | : Science |
ISBN | : 3527834192 |
Download Chiral Building Blocks in Asymmetric Synthesis Book in PDF, ePub and Kindle
Chiral Building Blocks in Asymmetric Synthesis A comprehensive introduction to the important classes of chiral building blocks Chirality — the asymmetric quality found in certain chemical compounds — plays an essential role in our world: chiral compounds can be found in biology, pharmaceutical compounds, agrochemicals, and fragrances. The stereoselective preparation of these complex molecular constructions constitutes a challenge. To this end, modern asymmetric synthesis utilizes a variety of valuable and efficient reagents employed as chiral auxiliaries, metal complexes and organocatalysts in stereoselective catalysis, and enantiopure reactants termed as chiral building blocks. In Chiral Building Blocks in Asymmetric Synthesis, the achievements in the fields of preparation of and applications of chiral blocks are presented. In doing so, the book comprehensively discusses the important classes of these reactants as the key for the asymmetric synthesis of chiral molecules. As such, it is an indispensable resource about synthetic methods, as well as possible modifications and transformations of important classes of chiral compounds. It also highlights the importance of their use as reactants and auxiliaries in the preparation of more sophisticated molecules or supramolecular systems. In Chiral Building Blocks in Asymmetric Synthesis readers will also find: Organization according to the most important compound classes — e.g. amino acids, BINOL and its derivatives, terpenes, and others — with an emphasis on synthesis and application A focus on the use of chiral building blocks for the preparation of bioactive compounds and supramolecular assemblies Chiral Building Blocks in Asymmetric Synthesis is a useful reference for organic chemists, catalytic chemists, chemists in industry, medicinal chemists, pharmaceutical chemists, and the libraries that support them.
Author | : Hwang-Hsing Chen |
Publisher | : |
Total Pages | : 428 |
Release | : 1985 |
Genre | : Chirality |
ISBN | : |
Download Design and synthesis of chiral auxiliaries for use in asymmetric synthesis Book in PDF, ePub and Kindle
Author | : James Morrison |
Publisher | : Elsevier |
Total Pages | : 216 |
Release | : 2012-12-02 |
Genre | : Science |
ISBN | : 032316000X |
Download Asymmetric Synthesis V1 Book in PDF, ePub and Kindle
Asymmetric Synthesis, Volume 1: Analytical Methods covers the major analytical methods used to determine enantiomeric ratios. This volume contains chapters that discuss the methods used to obtain chiral compounds and shows how to evaluate the chiral efficiency of an asymmetric synthesis. Analytical methods such as polarimetry, competitive reaction methods, isotope dilution, gas and liquid chromatography, and nuclear magnetic resonance methods are also discussed. Chemists and researchers in the field of pharmaceutical will find the book very useful.
Author | : Bozzano G Luisa |
Publisher | : Elsevier |
Total Pages | : 329 |
Release | : 1997-05-16 |
Genre | : Science |
ISBN | : 0080552005 |
Download Advances in Asymmetric Synthesis Book in PDF, ePub and Kindle
Advances in Asymmetric Synthesis