The Practice Of Peptide Synthesis PDF Download
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| Author | : Miklos Bodanszky |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 268 |
| Release | : 2013-11-11 |
| Genre | : Science |
| ISBN | : 364296835X |
Download The Practice of Peptide Synthesis Book in PDF, ePub and Kindle
During the years 1980-81, as guests of the Deutsches Woll forschungsinstitut in Aachen, Germany, we were working on a small book entitled, "Principles of Peptide Synthesis". In the library of the Institute we noted that the volumes of Houben-Weyl's Handbuch der Organischen Chemie dealing with peptide synthesis were so much in use that they were ready to fall apart because the researchers of the Institute consulted them with amazing regularity. They were looking for references, but even more for experimental details which could be adapted to the particular problem they happened to face. In planning a new synthetic endeavor they tried to lean on the experience of others in analogous situations. This suggested to us that a smaller and hence more tractable book may be needed, a volume which can be kept on or near the bench to make examples of funda mental methods readily available in the laboratory. Such a collection could save numerous short trips to the library, a point particularly important where a library well equipped with the sources of the literature of peptide synthesis is not near at hand. Also, we thought that the envisaged book may be welcome by those who are more versed in English than in German. To our best knowledge no similar publi cation is available.
| Author | : W. Chan |
| Publisher | : OUP Oxford |
| Total Pages | : 371 |
| Release | : 1999-12-16 |
| Genre | : Science |
| ISBN | : 0199637245 |
Download Fmoc Solid Phase Peptide Synthesis Book in PDF, ePub and Kindle
Since the publication of Atherton and Sheppard's volume, the technique of Fmoc solid-phase peptide synthesis has matured considerably and is now the standard approach for the routine production of peptides. The focus of this new volume is much broader, and covers the essential procedures.
| Author | : M. Bodanszky |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 320 |
| Release | : 2012-12-06 |
| Genre | : Science |
| ISBN | : 3642967639 |
Download Principles of Peptide Synthesis Book in PDF, ePub and Kindle
A look at the shelves of a major library awakens doubts in the author of this small volume about the importance of writing a new introduction to peptide synthesis. This rather narrow area of bio-organic chemistry already has received considerable attention. A whole series of books deals with the synthesis of peptides. Some of these are textbooks written to support lecture courses on peptide synthesis. Others try to help the beginner, otherwise well versed in organic chemistry, to embark on some experimental project that requires the construction of peptide chains. Not less useful are the monographs which were compiled to aid the adept practitioner and to provide him with references to the growing literature of a very active field. Is there any need for a new book on peptide synthesis? Should we add a new volume to an already impressive and certainly useful series? The answer is not obvious. The author has already participated in two similar en deavors. The first edition! of "Peptide Synthesis", with M. A. Ondetti as coauthor, was meant to serve as an introduction for the beginner. It was rather well received by researchers who joined the field of peptide chemistry and were looking for initiation. While working on the 2 second edition with Drs. Klausner and Ondetti, we became painfully aware of the impossibility of the task.
| Author | : Miklos Bodanszky |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 209 |
| Release | : 2012-12-06 |
| Genre | : Science |
| ISBN | : 364297886X |
Download Peptide Chemistry Book in PDF, ePub and Kindle
Analysis of peptides and determination of their primary structure. Conformational analysis: secondary-tertiary structure. Peptide synthesis: protection, activation and coupling, undesired reactions and their prevention, design of synthetic schemes.
| Author | : Knud J. Jensen |
| Publisher | : Humana |
| Total Pages | : 0 |
| Release | : 2016-08-27 |
| Genre | : Science |
| ISBN | : 9781493960040 |
Download Peptide Synthesis and Applications Book in PDF, ePub and Kindle
Peptides are used ubiquitously for studies in biology, biochemistry, chemical biology, peptide based medicinal chemistry, and many other areas of research. There is a number of marketed peptide drugs, and the prospects for the development of new peptide drugs are very encouraging. The second edition of Peptide Synthesis and Applications expands upon the previous editions with current, detailed methodologies for peptide synthesis. With new chapters on laboratory protocols for both the specialist and the non-specialist. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Peptide Synthesis and Application, Second Edition seeks to aid scientists in understanding different approaches to the synthesis of peptides by using a broad range of methods and strategies.
| Author | : Bruce Merrifield |
| Publisher | : |
| Total Pages | : 328 |
| Release | : 1993 |
| Genre | : Biography & Autobiography |
| ISBN | : |
Download Life During a Golden Age of Peptide Chemistry Book in PDF, ePub and Kindle
Thirteenth in a series of autobiographies of 22 eminent organic chemists, the present volume chronicles the life and contributions to the field of Bruce Merrifield, winner of the 1984 Nobel Prize for chemistry. Subtitled The Concept and Development of Solid-Phase Peptide Synthesis. Highly illustrated with diagrams, tables, graphs and (bandw) photographs. Annotation copyright by Book News, Inc., Portland, OR
| Author | : Gregg B. Fields |
| Publisher | : Academic Press |
| Total Pages | : 828 |
| Release | : 1997-10-21 |
| Genre | : Medical |
| ISBN | : |
Download Solid-Phase Peptide Synthesis Book in PDF, ePub and Kindle
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volumehas been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 275 volumes have been published (all of them still in print) and much of the material is relevant even today-truly an essential publication for researchers in all fields of life sciences. Key Features * Solid-phase peptide synthesis * Applications of peptides for structural and biological studies * Characterization of synthetic peptides
| Author | : Paul Lloyd-Williams |
| Publisher | : CRC Press |
| Total Pages | : 306 |
| Release | : 1997-04-23 |
| Genre | : Medical |
| ISBN | : 9780849391422 |
Download Chemical Approaches to the Synthesis of Peptides and Proteins Book in PDF, ePub and Kindle
Organic chemists working on the synthesis of natural products have long found a special challenge in the preparation of peptides and proteins. However, more reliable, more efficient synthetic preparation methods have been developed in recent years. This reference evaluates the most important synthesis methods available today, and also considers methods that show promise for future applications. This text describes the state of the art in efficient synthetic methods for the synthesis of both natural and artificial large peptide and protein molecules. Subjects include an introduction to basic topics, linear solid-phase synthesis of peptides, peptide synthesis in solution, convergent solid-phase synthesis, methods for the synthesis of branched peptides, formation of disulfide bridges, and more. The book emphasizes strategies and tactics that must be considered for the successful synthesis of peptides.
| Author | : N. Leo Benoiton |
| Publisher | : CRC Press |
| Total Pages | : 304 |
| Release | : 2016-04-19 |
| Genre | : Medical |
| ISBN | : 1420027697 |
Download Chemistry of Peptide Synthesis Book in PDF, ePub and Kindle
Chemistry of Peptide Synthesis is a complete overview of how peptides are synthesized and what techniques are likely to generate the most desirable reactions. Incorporating elements from the author's role of Career Investigator of the Medical Research Council of Canada and his extensive teaching career, the book emphasizes learning rather th
| Author | : Yi Yang |
| Publisher | : Academic Press |
| Total Pages | : 378 |
| Release | : 2015-09-01 |
| Genre | : Science |
| ISBN | : 0128011815 |
Download Side Reactions in Peptide Synthesis Book in PDF, ePub and Kindle
Side Reactions in Peptide Synthesis, based on the author’s academic and industrial experience, and backed by a thorough review of the current literature, provides analysis of, and proposes solutions to, the most frequently encountered side reactions during peptide and peptidomimetic synthesis. This valuable handbook is ideal for research and process chemists working with peptide synthesis in diverse settings across academic, biotech, and pharmaceutical research and development. While peptide chemistry is increasingly prevalent, common side reactions and their causes are often poorly understood or anticipated, causing unnecessary waste of materials and delay. Each chapter discusses common side reactions through detailed chemical equations, proposed mechanisms (if any), theoretical background, and finally, a variety of possible solutions to avoid or alleviate the specified side reaction. Provides a systematic examination on how to troubleshoot and minimize the most frequent side reactions in peptide synthesis Gives chemists the background information and the practical tools they need to successfully troubleshoot and improve results Includes optimization-oriented analysis of side reactions in peptide synthesis for improved industrial process development in peptidyl API (active pharmaceutical ingredient) production Answers the growing, global need for improved, replicable processes to avoid impurities and maintain the integrity of the end product. Presents a thorough discussion of critical factors in peptide synthesis which are often neglected or underestimated by chemists Covers solid phase and solution phase methodologies, and provides abundant references for further exploration
