The Pivotal Role Of Oral Microbiota Dysbiosis And Microbiota Host Interactions In Diseases Volume Ii PDF Download

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Oral Biofilms

Oral Biofilms
Author: S. Eick
Publisher: Karger Medical and Scientific Publishers
Total Pages: 247
Release: 2020-12-21
Genre: Medical
ISBN: 3318068527

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Biofilms are highly organized polymicrobial communities that are embedded in an extracellular matrix and formed on natural and artificial surfaces. In the oral cavity, biofilms are formed not only on natural teeth, but also on restorative materials, prosthetic constructions, and dental implants. Oral diseases like caries, gingivitis, periodontitis, and also pulp inflammation are associated with biofilms. This publication is an up-to-date overview on oral biofilms from different clinically relevant perspectives. Experts comprising basic researchers and clinicians report on recent research relating to biofilms - from general summaries to recommendations for daily clinical work. This book covers all aspects of oral biofilms, including models used in the laboratory, biofilms in dental water unit lines, periodontal and peri-implant biofilms, caries-related biofilms, halitosis, endodontic biofilms, and Candida infections, as well as biofilms on dental materials and on orthodontic appliances. Several chapters deal with anti-biofilm therapy, from the efficacy of mechanical methods and the use of antimicrobials, to alternative concepts. This publication is particularly recommended to dental medicine students, practitioners, other oral healthcare professionals, and scientists with an interest in translational research on biofilms.


Microbiota of the Human Body

Microbiota of the Human Body
Author: Andreas Schwiertz
Publisher: Springer
Total Pages: 160
Release: 2016-05-09
Genre: Science
ISBN: 3319312480

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Microbes can now be found in nearly every niche the human body offers. However, the complexity of the microbiota of a given site depends on the particular environmental condition thereof. Only microbes which are able to grow under these conditions, will prevail. Recent publications imply that the microorganisms do not only have multiple, critical consequences for host physiological processes such as postnatal development, immunomodulation and energy supply, but also effects on neurodevelopment, behavior and cognition. Within this book we will focus on the techniques behind these developments, epigenomics and on the various parts of the human body which are inhabited by microorganism such as the mouth, the gut, the skin and the vagina. In addition, chapters are dedicated to the possible manipulations of the microbiota by probiotics, prebiotics and faecal transplantation.


Microbial Endocrinology

Microbial Endocrinology
Author: Mark Lyte
Publisher: Springer Science & Business Media
Total Pages: 325
Release: 2010-04-06
Genre: Medical
ISBN: 1441955763

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Microbial endocrinology represents a newly emerging interdisciplinary field that is formed by the intersection of the fields of neurobiology and microbiology. This book will introduce a new perspective to the current understanding not only of the factors that mediate the ability of microbes to cause disease, but also to the mechanisms that maintain normal homeostasis. The discovery that microbes can directly respond to neuroendocrine hormones, as evidenced by increased growth and production of virulence-associated factors, provides for a new framework with which to investigate how microorganisms interface not only with vertebrates, but also with invertebrates and even plants. The reader will learn that the neuroendocrine hormones that one most commonly associates with mammals are actually found throughout the plant, insect and microbial communities to an extent that will undoubtedly surprise many, and most importantly, how interactions between microbes and neuroendocrine hormones can influence the pathophysiology of infectious disease.


The Gut Microbiome in Health and Disease

The Gut Microbiome in Health and Disease
Author: Dirk Haller
Publisher: Springer
Total Pages: 356
Release: 2018-07-27
Genre: Medical
ISBN: 3319905457

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The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.


The New Science of Metagenomics

The New Science of Metagenomics
Author: National Research Council
Publisher: National Academies Press
Total Pages: 170
Release: 2007-06-24
Genre: Science
ISBN: 0309106761

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Although we can't usually see them, microbes are essential for every part of human life-indeed all life on Earth. The emerging field of metagenomics offers a new way of exploring the microbial world that will transform modern microbiology and lead to practical applications in medicine, agriculture, alternative energy, environmental remediation, and many others areas. Metagenomics allows researchers to look at the genomes of all of the microbes in an environment at once, providing a "meta" view of the whole microbial community and the complex interactions within it. It's a quantum leap beyond traditional research techniques that rely on studying-one at a time-the few microbes that can be grown in the laboratory. At the request of the National Science Foundation, five Institutes of the National Institutes of Health, and the Department of Energy, the National Research Council organized a committee to address the current state of metagenomics and identify obstacles current researchers are facing in order to determine how to best support the field and encourage its success. The New Science of Metagenomics recommends the establishment of a "Global Metagenomics Initiative" comprising a small number of large-scale metagenomics projects as well as many medium- and small-scale projects to advance the technology and develop the standard practices needed to advance the field. The report also addresses database needs, methodological challenges, and the importance of interdisciplinary collaboration in supporting this new field.


Oral Mucosal Immunity and Microbiome

Oral Mucosal Immunity and Microbiome
Author: Georgios N. Belibasakis
Publisher: Springer Nature
Total Pages: 192
Release: 2019-11-15
Genre: Medical
ISBN: 3030285243

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The first International Conference on Oral Mucosal Immunity and Microbiome (OMIM) aimed to highlight cutting-edge basic and translational research from an oral immunological and microbiological perspective. Oral diseases with a microbial etiology are the most prevalent chronic diseases of humans. Whilst not life-threatening, they can significantly compromise quality of life, are associated with increased risk for certain systemic diseases, and pose heavy financial burdens to national health systems. Hence, periodontal and peri-implant diseases, dental caries, root canal infections and mucosal infections are significant global public health problems. In this book global experts summarize and discuss the latest progress made in oral mucosal immunity and the oral microbiome. Target audience is basic and/or translational researchers with expertise in host immunity and microbiome research, and interest in oral health and disease. This volume provides a much needed quantum leap in the field, by joining forces to address gaps at the oral mucosal immunity-microbiome cross-talk.


Periodontitis and Systemic Diseases

Periodontitis and Systemic Diseases
Author: Josefine Hirschfeld
Publisher: Quintessenz Verlag
Total Pages: 502
Release: 2021-04-19
Genre: Medical
ISBN: 3868675574

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The association between periodontitis and systemic diseases has become a hot topic in recent years. This comprehensive book reviews the clinical evidence and biological plausibility of the many systemic diseases that have been linked to periodontitis. Edited by Dr Josefine Hirschfeld and Prof Iain L.C. Chapple, experts in each field discuss the mechanisms at work, citing the available key literature and clearly summarising current knowledge and understanding of the associations between periodontitis and diabetes mellitus, cardiovascular diseases, chronic kidney disease, inflammatory bowel diseases, rheumatoid arthritis, respiratory diseases, pregnancy and fertility, malignancy, neurodegenerative diseases, stress and depression, and autoimmunity. Each chapter critically appraises the existing evidence, providing comprehensive, contemporary and well-considered insights into the clinical evidence and biological plausibility of each condition, as well as the limitations of existing studies and how these can be overcome in the future. Periodontitis and Systemic Diseases: Clinical Evidence and Biological Plausibility is an indispensable reference for both clinicians and researchers.


The Lung Microbiome

The Lung Microbiome
Author: Michael J. Cox
Publisher: European Respiratory Society
Total Pages: 261
Release: 2019-03-01
Genre: Medical
ISBN: 1849841020

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Studying the lung microbiome requires a specialist approach to sampling, laboratory techniques and statistical analysis. This Monograph introduces the techniques used and discusses how respiratory sampling, 16S rRNA gene sequencing, metagenomics and the application of ecological theory can be used to examine the respiratory microbiome. It examines the different components of the respiratory microbiome: viruses and fungi in addition to the more frequently studied bacteria. It also considers a range of contexts from the paediatric microbiome and how this develops to disease of all ages including asthma and chronic obstructive pulmonary disease, chronic suppurative lung diseases, interstitial lung diseases, acquired pneumonias, transplantation, cancer and HIV, and the interaction of the respiratory microbiome and the environment.