The Natural History Of Prostate Cancer In The Preclinical Phase PDF Download

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Clinical Oncology

Clinical Oncology
Author: Martin D. Abeloff
Publisher:
Total Pages: 0
Release: 2000
Genre: Cancer
ISBN: 9780443075452

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A must-have reference, this new edition provides practical information on treatment guidelines, details of diagnosis and therapy, and personal recommendations on patient management from experts in the field. Consistently formatted chapters allow for a user-friendly presentation for quick access of key information by the practicing clinician. Completely updated, this new edition includes all of the latest developments in treatment strategies of medical, surgical and radiation oncologists.


Concepts of Epidemiology

Concepts of Epidemiology
Author: Raj S. Bhopal
Publisher: Oxford University Press
Total Pages: 481
Release: 2016
Genre: Medical
ISBN: 0198739680

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First edition published in 2002. Second edition published in 2008.


Molecular Biology of Prostate Cancer

Molecular Biology of Prostate Cancer
Author: Manfred Wirth
Publisher: Walter de Gruyter
Total Pages: 220
Release: 2013-05-22
Genre: Medical
ISBN: 3110807270

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Nutritional Oncology

Nutritional Oncology
Author: George L. Blackburn
Publisher: Elsevier
Total Pages: 847
Release: 2011-05-02
Genre: Medical
ISBN: 0080454178

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Nutritional oncology is an increasingly active interdisciplinary field where cancer is investigated as both a systemic and local disease originating with the changes in the genome and progressing through a multi-step process which may be influenced at many points in its natural history by nutritional factors that could impact the prevention of cancer, the quality of life of cancer patients, and the risk of cancer recurrence in the rapidly increasing population of cancer survivors.Since the first edition of this book was published in 1999, the idea that there is a single gene pathway or single drug will provide a cure for cancer has given way to the general view that dietary/environmental factors impact the progression of genetic and cellular changes in common forms of cancer. This broad concept can now be investigated within a basic and clinical research context for specific types of cancer. This book attempts to cover the current available knowledge in this new field of nutritional oncology written by invited experts. This book attempts to provide not only the theoretical and research basis for nutritional oncology, but will offer the medical oncologist and other members of multidisciplinary groups treating cancer patients practical information on nutrition assessment and nutritional regimens, including micronutrient and phytochemical supplementation. The editors hope that this volume will stimulate increased research, education and patient application of the principles of nutritional oncology.NEW TO THIS EDITION:* Covers hot new topics of nutrigenomics and nutrigenetics in cancer cell growth * Includes new chapters on metabolic networks in cancer cell growth, nutrigenetics and nutrigenomics* Presents substantially revised chapters on breast cancer and nutrition, prostate cancer and nutrition, and colon cancer and nutrition* Includes new illustrations throughout the text, especially in the breast cancer chapter * Includes integrated insights into the unanswered questions and clearly defined objectives of research in nutritional oncology * Offers practical guidelines for clinicians advising malnourished cancer patients and cancer survivors on diet, nutrition, and lifestyle * Provides information on the role of bioactive substances, dietary supplements, phytochemicals and botanicals in cancer prevention and treatment


Introduction to Mathematical Oncology

Introduction to Mathematical Oncology
Author: Yang Kuang
Publisher: CRC Press
Total Pages: 291
Release: 2018-09-03
Genre: Mathematics
ISBN: 1498752977

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Introduction to Mathematical Oncology presents biologically well-motivated and mathematically tractable models that facilitate both a deep understanding of cancer biology and better cancer treatment designs. It covers the medical and biological background of the diseases, modeling issues, and existing methods and their limitations. The authors introduce mathematical and programming tools, along with analytical and numerical studies of the models. They also develop new mathematical tools and look to future improvements on dynamical models. After introducing the general theory of medicine and exploring how mathematics can be essential in its understanding, the text describes well-known, practical, and insightful mathematical models of avascular tumor growth and mathematically tractable treatment models based on ordinary differential equations. It continues the topic of avascular tumor growth in the context of partial differential equation models by incorporating the spatial structure and physiological structure, such as cell size. The book then focuses on the recent active multi-scale modeling efforts on prostate cancer growth and treatment dynamics. It also examines more mechanistically formulated models, including cell quota-based population growth models, with applications to real tumors and validation using clinical data. The remainder of the text presents abundant additional historical, biological, and medical background materials for advanced and specific treatment modeling efforts. Extensively classroom-tested in undergraduate and graduate courses, this self-contained book allows instructors to emphasize specific topics relevant to clinical cancer biology and treatment. It can be used in a variety of ways, including a single-semester undergraduate course, a more ambitious graduate course, or a full-year sequence on mathematical oncology.


Applied Biostatistical Principles and Concepts

Applied Biostatistical Principles and Concepts
Author: Laurens Holmes, Jr.
Publisher: Routledge
Total Pages: 324
Release: 2017-11-22
Genre: Medical
ISBN: 1315352214

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The past three decades have witnessed modern advances in statistical modeling and evidence discovery in biomedical, clinical, and population-based research. With these advances come the challenges in accurate model stipulation and application of models in scientific evidence discovery Applied Biostatistical Principles and Concepts provides practical knowledge using biological and biochemical specimen/samples in order to understand health and disease processes at cellular, clinical, and population levels. Concepts and techniques provided will help researchers design and conduct studies, then translate data from bench to clinics in attempt to improve the health of patients and populations. This book is suitable for both clinicians and health or biological sciences students. It presents the reality in statistical modelling of health research data in a concise manner that will address the issue of "big data" type I error tolerance and probability value, effect size and confidence interval for precision, effect measure modification and interaction as well as confounders, thus allowing for more valid inferences and yielding results that are more reliable, valid and accurate.


Malignancies of the Genitourinary Tract

Malignancies of the Genitourinary Tract
Author: Rolf Ackermann
Publisher: Springer Science & Business Media
Total Pages: 274
Release: 2012-12-06
Genre: Medical
ISBN: 3642845835

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Malignancies originating from the urogenital tract account for about 20% of all solid neoplasias. The various tumor types, including carcinoma of the prostate, transitional cell carcinoma, renal cell carcinoma, and testicular germ cell tumors, differ widely in terms of biological features, in cidence and appearance, diagnostic work-up and manage ment. It is not surprising that this complexity of urologic oncology with its related problems has increasingly attracted both experimental investigators and clinical experts. Only time will tell whether the achievements that today are con sidered· as progress will turn out to be significant contribu tions towards the ultimate goal: the cure of the patients' life-threatening diseases with little or no side effects. How ever, many innovations and improvements have already taken place in the field of urologic oncology within recent years. The high pace of innovative development requires continuous, thorough, and critical updating of our kowledge so that persisting deficits can be defined: the basic require ment for posing new scientific questions. The following examples may serve to illustrate the recent developments and the resulting new problems and questions: Recently, it has become evident that carcinoma of the prostate must be detected earlier to enable us to cure more of the affected patients in the future than currently.


Gordis Epidemiology E-Book

Gordis Epidemiology E-Book
Author: David D Celentano
Publisher: Elsevier Health Sciences
Total Pages: 537
Release: 2023-11-07
Genre: Medical
ISBN: 0323877761

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Continuing in the tradition of award-winning educator and epidemiologist Dr. Leon Gordis, Gordis Epidemiology, 7th Edition, provides a solid introduction to basic epidemiologic principles as well as practical applications in public health and clinical practice, highlighted by real-world examples throughout. Written by Drs. David D Celentano, Moyses Szklo, and Youssef Farag of Johns Hopkins University, this bestselling text is known for its reader-friendly, accessible writing style and practical approach to a complex and challenging subject, making it a favorite text of students as well as an ideal resource for health care providers, health policy makers, and epidemiologists at all levels of training and practice. Covers the basic principles and concepts of epidemiology in a clear, uniquely memorable way, using a wealth of full-color figures, graphs, charts, and cartoons to help you understand and retain key information. Includes new examples and cases reflecting modern epidemiology, including lessons from the COVID-19 pandemic and other current topics of interest. Reflects how epidemiology is practiced today, with chapters progressing from observation and developing hypotheses to data collection and analyses. Features end-of-chapter questions for quick self-assessment, and a glossary of genetic terminology. Provides more than 200 additional multiple-choice self-assessment questions online. Provides a strong basis for understanding the role and importance of epidemiology in today’s data-driven society. Evolve Instructor site with an image/table collection, test bank, and more is available to instructors through their Elsevier sales rep or via request at https://evolve.elsevier.com.