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Blood Vessels and Lymphatics in Organ Systems

Blood Vessels and Lymphatics in Organ Systems
Author: David Abramson
Publisher: Academic Press
Total Pages: 792
Release: 2012-12-02
Genre: Science
ISBN: 0323140661

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Blood Vessels and Lymphatics on Organ Systems provides an introduction to the general and the specific characteristics of blood vessels and lymphatics in organ systems. It offers a structured, multidisciplinary approach to the broad field of vascular science, emphasizing both established and recent concepts. These include vascular networks such as those in the pineal, parathyroids, pancreas, adrenals, adipose tissue, and special senses; and functions of vascular endothelium. The book is organized into two parts. Part One on the general properties of blood vessels and lymphatics deals with the general aspects of the arteries, veins, microcirculation, and lymphatic channels. Part Two discusses the embryologic, morphologic, physiologic, pharmacologic, pathophysiologic, and pathologic characteristics of blood and lymph circulations in each of the important organ systems. This book was written for graduate students in the areas of blood and lymph circulation and for advanced research workers or clinicians seeking sources of information on advances in cardiovascular science.


Blood Vessels and Lymphatics

Blood Vessels and Lymphatics
Author: David I. Abramson
Publisher: Elsevier
Total Pages: 833
Release: 2013-09-24
Genre: Medical
ISBN: 1483261417

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Blood Vessels and Lymphatics focuses on the embryology, anatomy, physiology, pharmacology, biochemistry, and pathology of blood vessels and lymphatics. The selection first offers information on the embryology and gross, microscopic and submicroscopic anatomy, biophysical principles and physiology, and pharmacology and biochemistry of arterial and arteriolar systems. The text then takes a look at the sympathetic innervation of arterial tree. The publication examines microcirculation and the venous system, including the structural basis of microcirculation, exchange of materials across capillary wall, pathology of microcirculation, biochemistry, and pharmacology. The book then elaborates on coronary, pulmonary, and gastrointestinal circulation, blood vessels of the pituitary and the thyroid, and disorders affecting arterial or venous circulation. The selection is a vital source of information for readers interested in the study of blood vessels and lymphatics.


Skeletal Muscle Circulation

Skeletal Muscle Circulation
Author: Ronald J. Korthuis
Publisher: Morgan & Claypool Publishers
Total Pages: 147
Release: 2011
Genre: Medical
ISBN: 1615041834

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The aim of this treatise is to summarize the current understanding of the mechanisms for blood flow control to skeletal muscle under resting conditions, how perfusion is elevated (exercise hyperemia) to meet the increased demand for oxygen and other substrates during exercise, mechanisms underlying the beneficial effects of regular physical activity on cardiovascular health, the regulation of transcapillary fluid filtration and protein flux across the microvascular exchange vessels, and the role of changes in the skeletal muscle circulation in pathologic states. Skeletal muscle is unique among organs in that its blood flow can change over a remarkably large range. Compared to blood flow at rest, muscle blood flow can increase by more than 20-fold on average during intense exercise, while perfusion of certain individual white muscles or portions of those muscles can increase by as much as 80-fold. This is compared to maximal increases of 4- to 6-fold in the coronary circulation during exercise. These increases in muscle perfusion are required to meet the enormous demands for oxygen and nutrients by the active muscles. Because of its large mass and the fact that skeletal muscles receive 25% of the cardiac output at rest, sympathetically mediated vasoconstriction in vessels supplying this tissue allows central hemodynamic variables (e.g., blood pressure) to be spared during stresses such as hypovolemic shock. Sympathetic vasoconstriction in skeletal muscle in such pathologic conditions also effectively shunts blood flow away from muscles to tissues that are more sensitive to reductions in their blood supply that might otherwise occur. Again, because of its large mass and percentage of cardiac output directed to skeletal muscle, alterations in blood vessel structure and function with chronic disease (e.g., hypertension) contribute significantly to the pathology of such disorders. Alterations in skeletal muscle vascular resistance and/or in the exchange properties of this vascular bed also modify transcapillary fluid filtration and solute movement across the microvascular barrier to influence muscle function and contribute to disease pathology. Finally, it is clear that exercise training induces an adaptive transformation to a protected phenotype in the vasculature supplying skeletal muscle and other tissues to promote overall cardiovascular health. Table of Contents: Introduction / Anatomy of Skeletal Muscle and Its Vascular Supply / Regulation of Vascular Tone in Skeletal Muscle / Exercise Hyperemia and Regulation of Tissue Oxygenation During Muscular Activity / Microvascular Fluid and Solute Exchange in Skeletal Muscle / Skeletal Muscle Circulation in Aging and Disease States: Protective Effects of Exercise / References


Anatomy and Physiology

Anatomy and Physiology
Author: J. Gordon Betts
Publisher:
Total Pages: 0
Release: 2013-04-25
Genre:
ISBN: 9781947172807

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Lymphatic Structure and Function in Health and Disease

Lymphatic Structure and Function in Health and Disease
Author: Felicity N.E. Gavins
Publisher: Academic Press
Total Pages: 180
Release: 2019-10-23
Genre: Medical
ISBN: 0128156465

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Lymphatic Structure and Function in Health and Disease serves as a resource book on what has been learned about lymphatic structure, function and anatomy within different organ systems. This is the first book to bring together lymphatic medicine as a whole, with in-depth analysis of specific aspects of lymphatics in different vascular pathologies. This book is a useful tool for scientists, practicing clinicians and residents, in particular, those in vascular biology, neurology, cardiology and general medicine. Chapters discuss topics such as ontogeny and phylogeny of lymphatics, lymphatic pumping, CNS lymphatics, lymphatics in transplant and lymphatic reconstruction. Brings together lymphatic medicine as a whole, with an in-depth analysis of the specific basic science aspects of lymphatic structure and function Covers the clinical aspects of lymphatics in different vascular pathologies Co-published with the International Society of Neurovascular Diseases Discusses lymphatic structure and function in all of the major organ systems


Capillary Fluid Exchange

Capillary Fluid Exchange
Author: Joshua Scallan
Publisher: Morgan & Claypool Publishers
Total Pages: 86
Release: 2010
Genre: Science
ISBN: 1615040668

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The partition of fluid between the vascular and interstitial compartments is regulated by forces (hydrostatic and oncotic) operating across the microvascular walls and the surface areas of permeable structures comprising the endothelial barrier to fluid and solute exchange, as well as within the extracellular matrix and lymphatics. In addition to its role in the regulation of vascular volume, transcapillary fluid filtration also allows for continuous turnover of water bathing tissue cells, providing the medium for diffusional flux of oxygen and nutrients required for cellular metabolism and removal of metabolic byproducts. Transendothelial volume flow has also been shown to influence vascular smooth muscle tone in arterioles, hydraulic conductivity in capillaries, and neutrophil transmigration across postcapillary venules, while the flow of this filtrate through the interstitial spaces functions to modify the activities of parenchymal, resident tissue, and metastasizing tumor cells. Likewise, the flow of lymph, which is driven by capillary filtration, is important for the transport of immune and tumor cells, antigen delivery to lymph nodes, and for return of filtered fluid and extravasated proteins to the blood. Given this background, the aims of this treatise are to summarize our current understanding of the factors involved in the regulation of transcapillary fluid movement, how fluid movements across the endothelial barrier and through the interstitium and lymphatic vessels influence cell function and behavior, and the pathophysiology of edema formation. Table of Contents: Fluid Movement Across the Endothelial Barrier / The Interstitium / The Lymphatic Vasculature / Pathophysiology of Edema Formation


Human Anatomy: A Very Short Introduction

Human Anatomy: A Very Short Introduction
Author: Leslie Klenerman
Publisher: OUP Oxford
Total Pages: 177
Release: 2015-02-26
Genre: Science
ISBN: 019101706X

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A vast subject that includes a strange vocabulary and an apparent mass of facts, human anatomy can at first appear confusing and off-putting. But the basic construction of the human body - the skeleton, the organs of the chest and abdomen, the nervous system, the head and neck with its sensory systems and anatomy for breathing and swallowing - is vital for anyone studying medicine, biology, and health studies. In this Very Short Introduction Leslie Klenerman provides a clear, concise, and accessible introduction to the structure, function, and main systems of the human body, including a number of clear and simple illustrations to explain the key areas. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.


Atlas of Lymphoscintigraphy and Sentinel Node Mapping

Atlas of Lymphoscintigraphy and Sentinel Node Mapping
Author: Giuliano Mariani
Publisher: Springer Science & Business Media
Total Pages: 306
Release: 2012-12-23
Genre: Medical
ISBN: 8847027667

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Although lymphoscintigraphy was originally introduced into clinical routine for identification of the cause of peripheral edema, more recently it has been widely applied for radioguided biopsy of the sentinel lymph node in patients with solid cancers. The procedure is now considered crucial for adequate planning of oncologic surgery in a growing number of cancers. This atlas presents a collection of richly illustrated teaching cases that demonstrate the clinical relevance and impact of lymphoscintigraphy in different pathologic conditions. After introductory chapters on the anatomy, physiology, and pathophysiology of lymphatic circulation, the role of lymphoscintigraphy in differential diagnosis of peripheral edema and characterization of intracavitary lymph effusions is addressed. The principal focus of the book, however, is on the use of lymphoscintigraphic mapping for radioguided sentinel node biopsy in cutaneous melanoma and cancers at a range of anatomic sites. The most commonly observed lymphoscintigraphic patterns are depicted, and anatomic variants and technical pitfalls of the procedure receive careful attention. The role of tomographic multimodality imaging is also considered. The atlas will be an excellent learning tool for residents in nuclear medicine and other specialists with an interest in the field.