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The Molecular Medicine of Viral Hepatitis

The Molecular Medicine of Viral Hepatitis
Author: Tim J. Harrison
Publisher: Wiley
Total Pages: 282
Release: 1997-01-24
Genre: Medical
ISBN: 9780471969969

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This series is designed to bridge the gap between pure research in the biomedical sciences and its practical application in clinical medicine. The objective is to promote the understanding of the molecular basis of human physiology and disease, and new techniques for diagnosis and treatment. Primarily intended for graduate students of medicine, the books will also be of use to molecular biologists, biochemists, physiologists, pharmacologists and biotechnologists, as well as medical practitioners and technicians who seek to update their knowledge. The Molecular Medicine of Viral Hepatitis Edited by Tim J. Harrison and Arie J. Zuckerman Royal Free Hospital School of Medicine, London, UK General texts on diagnostic and clinical aspects of viral hepatitis abound. The Molecular Medicine of Viral Hepatitis focuses on those areas of research where advances are presently being mode and offers new ideas on the development of vaccines, diagnostic tests and therapeutic agents. Chapters include: The molecular biology of attenuation of hepatitis A virus Development of vaccines against hepatitis E virus infection The molecular role of hepatitis B virus in the development of hepatocellular carcinoma Genotypes and genetic variation of hepatitis C virus As such this volume will be indispensable to clinicians and researchers in virology, hepatology, microbiology, vaccinology, oncology and gastroenterology.


Viral Hepatitis Molecular Biology Diagnosis and Control

Viral Hepatitis Molecular Biology Diagnosis and Control
Author: Isa K. Mushahwar
Publisher: Gulf Professional Publishing
Total Pages: 298
Release: 2004
Genre: Medical
ISBN: 9780444514875

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The last forty years have witnessed the discovery of five human hepatitis viruses: hepatitis virus A, B, C, D, and E, and two related blood-borne viruses: GB virus C and TT virus. Viral Hepatitis provides a comprehensive overview of the latest developments and research studies in human viral hepatitis. Written by leading international scientists in the field, this book covers topics ranging from the history of these viruses to their molecular biology, diagnosis, epidemiology and control. It will be an invaluable reference source for hepatitis researchers, reference and diagnostic laboratories, clinicians, public health officers and graduate and medical students. Book jacket.


Viral Hepatitis

Viral Hepatitis
Author: Arie J. Zuckerman
Publisher:
Total Pages: 612
Release: 1993
Genre: Medical
ISBN:

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Discusses all aspects of viral hepatitis, from structure and molecular virology, and natural history and experimental models, to epidemiology, diagnosis and prevention. A section on clinical aspects covers transfusion-associated hepatitis, occupational aspects and paediatric infection.


Viral Hepatitis

Viral Hepatitis
Author: E.A. Fagan
Publisher: Garland Science
Total Pages: 328
Release: 2003-12-16
Genre: Science
ISBN: 1135326436

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This book aims to bridge the widening rift between clinical and molecular aspects of viral hepatitis by providing an up-to-date overview of the field. The focus is practical and covers the limitations of clinical diagnosis, the interpretation of tests bas


Molecular Biology Of Human Hepatitis Viruses

Molecular Biology Of Human Hepatitis Viruses
Author: Joao Monjardino
Publisher: World Scientific
Total Pages: 149
Release: 1998-05-30
Genre: Medical
ISBN: 1783262605

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Hepatitis A and B viruses have infected nearly half the current world population; and as many as 500 million people are still infected with the hepatitis B or C virus today. Hepatitis B vaccination is effective but not universally adopted and no vaccine is available against hepatitis C. Treatment is prohibitively expensive for areas of high endemicity or prevalence and not universally effective.This important and timely book covers recent advances in understanding the molecular biology of hepatitis viruses. The advances have contributed new insights into the molecular mechanisms involved in replication of genetic information and in gene expression; and have translated into diagnostics; prevention and development of antiviral drugs.


Frontiers in Viral Hepatitis

Frontiers in Viral Hepatitis
Author: R.F. Schinazi
Publisher: Elsevier
Total Pages: 608
Release: 2003-12-12
Genre: Medical
ISBN: 9780444509864

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Cutting-edge collection of reviews and articles on HBV and HCV, as well as new emerging hepatitis viruses. Subjects include regulatory issues, epidemiology, emerging viruses, immunology, vaccines, pediatric HBV and HCV, genetics, pathology, viral diagnosis, cell systems, animal models, drug discovery and development, and prevention and treatment options for hepatocellular carcinoma. Book jacket.


Molecular Components of Hepatitis B Virus

Molecular Components of Hepatitis B Virus
Author: M. Feitelson
Publisher: Springer Science & Business Media
Total Pages: 283
Release: 2012-12-06
Genre: Medical
ISBN: 1461325730

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Since the discovery of Australia antigen and its association with type B hepatitis, molecular characterization of the components making up hepatitis B virus (RBV) have been pursued with worldwide interest. Over the past two decades, such characterization has led to the development of sensitive assays to screen and exclude contaminated units from blood banks and has recently resulted in the licensing of several RBV vaccines. That more than 200 million people worldwide are chronically infected with RBV, and that they are at a high risk for the development of chronic hepatitis and hepatocellular carcinoma, still represent formidable problems in our understanding of host-virus relationships on the molecular level. In the absence of a suitable tissue culture system, and with a very limited host range of infection, characterization of RBV on the molecular level has made remarkable progress recently with the advent of genome cloning, sequencing and expression of individual virus genes by recombinant DNA technology. The presence of hepatitis B-like viruses in an expanding number of animal hosts, and the possibility of virus replication in cells other than hepatocytes, provide great promise that future work will elucidate the molecular mechanisms operative in the various outcomes of RBV infection.


Viral Hepatitis and Liver Disease

Viral Hepatitis and Liver Disease
Author: Kusuya Nishioka
Publisher: Springer Science & Business Media
Total Pages: 1384
Release: 2012-12-06
Genre: Medical
ISBN: 4431682554

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A series of international symposia on viral hepatitis and liver disease has been held triannially, and called the "Olympics" of this research field. Our book presents the results of the eighth of these "Olympiads" which for the first time, was held in Asia (May 1993, Tokyo). Due to the rapid progress in research on both basic and clinical aspects of viral hepatitis and liver disease, the state of the art in this field is continually being updated, and our book provides a broad and in-depth survey of current work. The major topics in our book include molecular biology of the five known hepatitis viruses (HAV, HBV, HCV, HDV, and HEV), clinical implications of genetic variants of HBV and HCV, interferon treatment of HCV-related liver disease, and worldwide epidemiology and control of viral hepatitis. New subjects not seen in previous books, such as genotypes of HCV, are also covered. Expanding knowledge about the heterogeneity of the HCV genome has revealed a great variety of genotypes as well as their association with host pathogenesis and their varying responsiveness to interferon therapy. The first promising results of efforts to develop a hepatitis C vaccine are also presented. Finally, compared with its predecessors, our book contains many more papers from Asian countries, where the prevalence of viral hepatitis and liver disease is the highest in the world.


Viral Hepatitis

Viral Hepatitis
Author: Howard C. Thomas
Publisher: John Wiley & Sons
Total Pages: 645
Release: 2013-07-22
Genre: Medical
ISBN: 111863733X

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The 4th edition of Viral Hepatitis covers comprehensively the entire complex field of infections caused by all of the different hepatitis viruses, which affect many millions of people throughout the world with considerable morbidity and mortality. Howard Thomas and Arie Zuckerman are joined by Anna Lok from the USA and Stephen Locarnini from Australia as Editors. They have recruited leading researchers and physicians from many countries, who have produced an authoritative account of current knowledge and research on this important infection, including new insights into immune response to HBV and HCV. The result is a comprehensive account on all aspects of viral hepatitis, including rapid advances in the diagnosis, management, treatment and prevention of a complex infection, which in the case of hepatitis B, C and D may lead to severe complications including chronic hepatitis, cirrhosis and hepatocellular carcinoma. The latest edition of Viral Hepatitis offers an essential resource of current information for hepatologists, gastroenterologists, infectious diseases specialists and other clinicians, researchers, public health physicians and National and International Health Authorities.


Hepatitis C Protocols

Hepatitis C Protocols
Author: Johnson Y. N. Lau
Publisher: Humana
Total Pages: 621
Release: 2013-08-21
Genre: Medical
ISBN: 9781489943484

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The identification of hepatitis C virus by Michael Houghton and his c- leagues at the Chiron Corporation nearly years ago represented a technical tour de force of modern molecular medicine. This breakthrough not only unearthed the causative agent of non-A non-B hepatitis that had eluded the best of scientists for more than 20 years, but also was symbolic of another chapter in the changing paradigm of modern science and medicine. The re- lutionary concept of identifying a pathogen without actually visualizing or detecting it will forever redefine the way we approach pathogenesis of d- eases whose cause is unknown. It is benefitting that this discovery treads on the heels of the human immunodeficiency pandemic, and parallels the ala- ing emergence of various microbial pestilences in the world. Despite the rapid advances in our understanding of the virus, there is much remaining to learn about it. This book highlights some of the important areas yet to be unraveled. As illustrated in this book, the marriage between basic science and clinical medicine is essential in our quest for these unknowns. The last decade has focused on the fundamentals of the virus; the next decade must underscore translational research, bridging clinical medicine and basic science with re- ization of fundamental knowledge to improve prevention, diagnosis, and tre- ment of viral hepatitis C.