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The Membrane Hypothesis of Aging

The Membrane Hypothesis of Aging
Author: Imre Zs.-Nagy
Publisher: CRC Press
Total Pages: 226
Release: 1994-07-12
Genre: Science
ISBN: 9780849367380

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The Membrane Hypothesis of Aging offers the most comprehensive, multidisciplinary description of the cell maturation and aging process. The membrane hypothesis of aging (MHA) described in this book is based on the actual multidisciplinary knowledge of cell morphology, physiology, and biochemistry. The solid basis of known facts explains the destructive, progressive, intrinsic, and universal character of the aging process. The book interprets other aging theories, including free radical theory of aging, dysdifferentiation hypothesis of aging and cancer, and the accumulation theories. It presents important issues for future research. The book also outlines the possibilities of an efficient, preventive, anti-aging drug design, and presents the first promising results of such research activity.


Brain Aging

Brain Aging
Author: David R. Riddle
Publisher: CRC Press
Total Pages: 408
Release: 2007-04-19
Genre: Medical
ISBN: 9781420005523

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Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur


Encyclopedia of Aging and Public Health

Encyclopedia of Aging and Public Health
Author: Sana Loue
Publisher: Springer Science & Business Media
Total Pages: 852
Release: 2008-01-16
Genre: Medical
ISBN: 0387337539

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Americans are living longer, and the elder population is growing larger. To meet the ongoing need for quality information on elder health, the Encyclopedia of Aging and Public Health combines multiple perspectives to offer readers a more accurate and complete picture of the aging process. The book takes a biopsychosocial approach to the complexities of its subject. In-depth introductory chapters include coverage on a historical and demographic overview of aging in America, a guide to biological changes accompanying aging, an analysis of the diversity of the U.S. elder population, legal issues commonly affecting older adults, and the ethics of using cognitively impaired elders in research. From there, over 425 entries cover the gamut of topics, trends, diseases, and phenomena: -Specific populations, including ethnic minorities, custodial grandparents, and centenarians -Core medical conditions associated with aging, from cardiac and pulmonary diseases to Parkinson’s and Alzheimer’s -Mental and emotional disorders -Drugs/vitamins/alternative medicine -Disorders of the eyes, feet, and skin -Insomnia and sleep disorders; malnutrition and eating disorders -Sexual and gender-related concerns -And a broad array of social and political issues, including access to care, abuse/neglect, veterans’ affairs, and assisted suicide Entries on not-quite-elders’ concerns (e.g., midlife crisis, menopause) are featured as well. And all chapters and entries include references and resource lists. The Encyclopedia has been developed for maximum utility to clinicians, social workers, researchers, and public health professionals working with older adults. Its multidisciplinary coverage and scope of topics make this volume an invaluable reference for academic and public libraries.


Aging Interventions and Therapies

Aging Interventions and Therapies
Author: Suresh I S Rattan
Publisher: World Scientific
Total Pages: 428
Release: 2005-05-06
Genre: Science
ISBN: 9814481513

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' This comprehensive volume surveys the molecular, cellular, hormonal, nutritional, medical and lifestyle strategies being tested and applied for the prevention, intervention and treatment of age-related diseases. With authoritative contributions not just from researchers in academic institutions and pharmaceutical and cosmeceutical industries, but also practicing clinicians of both mainstream and alternative medicine, demographers and bioethicists, this book provides unique scientific, ethical and social perspectives on the discussion of aging intervention. In addition, the latest technologies in development, which will have serious bearings on future aging interventions, are reviewed. Aging Interventions and Therapies is ideal for graduates and undergraduates in universities and medical and nursing colleges, as well as post-graduates researching different aspects of aging and anti-aging. The topics covered are also highly relevant for professionals in the pharmaceutical, cosmeceutical, nutrition and healthcare industries, and practicing clinicians looking for a reliable and up-to-date resource on aging intervention and therapy. Contents:The Ethics of Aging Intervention and Life-Extension (S Horrobin)Prevention and Treatment of Skin Aging (J L McCullogh & K M Kelly)Industrial Approaches Towards Developing Effective Skin Care Products (T Blatt et al.)Strategies to Reduce Age-Related Skeletal Muscle Wasting (G S Lynch et al.)Antioxidants and Aging in Human Beings (É Le Bourg)Hormone Therapy for Aging (M K Thakur)Pineal Peptides as Modulators of Aging (V N Anisimov & V K Khavinson)Melatonin: Anti-Aging Perception and Current Perspectives (A L Bhatia)Zinc and Other Micronutrients for Healthy Aging (E Mocchegiani et al.)Calorie Restriction as a Potent Anti-Aging Intervention: Modulation of Oxidative Stress (B P Yu)Nutritional Interventions in Aging and Age-Associated Disorders (K Kitani)Telomere- and Telomerase Based Therapies (M A Cerone et al.)Clinical Perspective of the Present Status of Treatment for Major Age-Related Diseases (A Syngle)Indian Ayurvedic Medicine in Aging Prevention and Treatment (B P S Vohra & S K Gupta)Alzheimer's Disease: Current and Future Treatments (U Kumar)Stem Cells, Regenerative Medicine and Aging (M Kassem)Principles and Practice of Hormesis as an Aging Intervention (S I S Rattan)Forseeable and More Distant Rejuvenation Therapies (A D N J de Grey)Anti-Aging Medicine and the Quest for Immortality (S J Olshansky & B A Carnes) Readership: Graduate and undergraduate students, researchers, and professionals working in the healthcare, cosmetics and cosmeceutical industries. Keywords:Aging;Anti-Aging;Lifespan;Longevity;Healthy Aging;Gerontogenes;Exercise;StressKey Features:Provides state-of-the-art information on the success and failure of various anti-aging approaches, such as hormone therapy, melatonin, biopeptides, nutrition, antioxidants, micronutrients, herbs, exercise and cosmeticsChallenges and re-defines common beliefs and ideas about aging intervention and lifespan prolongationEvaluates the advantages and disadvantages of prevalent treatments for age-related diseasesEvaluates therapeutic approaches under test and development against Alzheimer's disease, mitochondrial diseases, and for better skin careReviews:“This book tackles a frontier medicine and has the merit to have harmoniously ‘cross-linked’ opinion leaders in many different aspects of the field, rendering it very amenable to students, basic scientists and clinicians, and is an absolute must for the dedicated researchers.”Biogerontology '


Human Longevity

Human Longevity
Author: Raymond C. Valentine
Publisher: CRC Press
Total Pages: 248
Release: 2014-09-18
Genre: Medical
ISBN: 146659487X

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More than 7 billion people inhabit the earth and all of them are subject to aging. This book is aimed at persons interested in a molecular explanation of how our cells age. Human Longevity: Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution is built on the proposition that we age as our mitochondria age. It suggests a revised vers


Aging

Aging
Author: L. Robert
Publisher: Karger Medical and Scientific Publishers
Total Pages: 226
Release: 2014-05-16
Genre: Medical
ISBN: 3318026530

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Aging inspired a large number of theories trying to rationalize the aging process common to all living beings. In this publication the most important environmental and intrinsic mechanisms involved in the aging process and in its pathological consequences are reviewed. Furthermore theoretical and experimental evidence of the most important theoretical elements based on Darwinian evolution, cellular aging, role of cell membranes, free radicals and oxidative processes, receptor-mediated reactions, the extracellular matrix and immune functions as well as the most important environmental and intrinsic mechanisms involved in the aging process and in its pathological consequences are discussed. These presentations of theories and related experimental facts give a global overview of up to date concepts of the biology of the aging process and are of essential reading not only for specialists in this field but also for practitioners of scientific, medical, social and experimental sciences.


Biology of Aging

Biology of Aging
Author: Robert Zwilling
Publisher: Springer Science & Business Media
Total Pages: 181
Release: 2012-12-06
Genre: Medical
ISBN: 3642857892

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bhe aim of the book was not to focus the age-dependent modifications of one specific biological systems or phenomena, but the attempt was pursued to cover several fields in which the biological research on aging is going on. The fundamental purpose of this planning was to offer the PhD students an advanced text that could raise the possibility of an interdisciplinary discussion on a wide and complex field that is very suitable to be utilized as an example of the connection existing between advanced teaching and experimental research.


Challenges of Biological Aging

Challenges of Biological Aging
Author: Edward J. Masoro, PhD
Publisher: Springer Publishing Company
Total Pages: 217
Release: 1999-07-16
Genre: Social Science
ISBN: 0826117112

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This volume provides the non-biologist an overview of what is known about the physiological bases of aging. The author examines the many basic theories and emerging hypotheses underlying the molecular, cellular, and systemic processes involved in senescence. He addresses the normal physiological changes that characterize the aging phenotype, and also considers the role of many age-associated diseases in growing older. Masoro synthesizes a much-needed ìunified theoryî of biological aging to which explains how and why the body grows into the condition we call ìold.î This text is intended for gerontology students in training, as well as for human physiologists interested in gerontology.


The Aging Mind

The Aging Mind
Author: National Research Council
Publisher: National Academies Press
Total Pages: 285
Release: 2000-04-18
Genre: Social Science
ISBN: 0309172195

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Possible new breakthroughs in understanding the aging mind that can be used to benefit older people are now emerging from research. This volume identifies the key scientific advances and the opportunities they bring. For example, science has learned that among older adults who do not suffer from Alzheimer's disease or other dementias, cognitive decline may depend less on loss of brain cells than on changes in the health of neurons and neural networks. Research on the processes that maintain neural health shows promise of revealing new ways to promote cognitive functioning in older people. Research is also showing how cognitive functioning depends on the conjunction of biology and culture. The ways older people adapt to changes in their nervous systems, and perhaps the changes themselves, are shaped by past life experiences, present living situations, changing motives, cultural expectations, and emerging technology, as well as by their physical health status and sensory-motor capabilities. Improved understanding of how physical and contextual factors interact can help explain why some cognitive functions are impaired in aging while others are spared and why cognitive capability is impaired in some older adults and spared in others. On the basis of these exciting findings, the report makes specific recommends that the U.S. government support three major new initiatives as the next steps for research.