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The Meaning of Nucleocytoplasmic Transport

The Meaning of Nucleocytoplasmic Transport
Author: Paul S. Agutter
Publisher: Springer Science & Business Media
Total Pages: 205
Release: 2013-06-29
Genre: Science
ISBN: 3662225026

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The means by which proteins and RNAs are exchanged between cytoplasm and nucleus have interested cell biologists for many years, and the field has seen a number of exciting recent advances. Much has been learned about the intricate architecture of the nuclear pore-complex, the mechanisms by which transport substrates are sorted, and the supply of energy for exchange processes. This book attempts a general review of the growing body of knowledge. However, the authors challenge the presumptions implicit in some interpretations of the evidence, re-examining the concept of "transport" within cells, and suggesting that lessons learned from nucleocytoplasmic transport studies can elucidate wider aspects of cell biology.


Nucleocytoplasmic Transport

Nucleocytoplasmic Transport
Author: Reiner Peters
Publisher: Springer Science & Business Media
Total Pages: 296
Release: 2012-12-06
Genre: Science
ISBN: 3642715656

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Challenges in Delivery of Therapeutic Genomics and Proteomics

Challenges in Delivery of Therapeutic Genomics and Proteomics
Author: Ambikanandan Misra
Publisher: Elsevier
Total Pages: 686
Release: 2010-09-09
Genre: Science
ISBN: 0123849659

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Delivery of therapeutic proteomics and genomics represent an important area of drug delivery research. Genomics and proteomics approaches could be used to direct drug development processes by unearthing pathways involved in disease pathogenesis where intervention may be most successful. This book describes the basics of genomics and proteomics and highlights the various chemical, physical and biological approaches to protein and gene delivery. Covers a diverse array of topics from basic sciences to therapeutic applications of proteomics and genomics delivery Of interest to researchers in both academia and industry Highlights what’s currently known and where further research is needed


Nuclear-Cytoplasmic Transport

Nuclear-Cytoplasmic Transport
Author: Weidong Yang
Publisher: Springer
Total Pages: 277
Release: 2018-07-27
Genre: Science
ISBN: 3319773097

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Dysfunction of nuclear-cytoplasmic transport systems has been associated with many human diseases. Thus, understanding of how functional this transport system maintains, or through dysfunction fails to maintain remains the core question in cell biology. In eukaryotic cells, the nuclear envelope (NE) separates the genetic transcription in the nucleus from the translational machinery in the cytoplasm. Thousands of nuclear pore complexes (NPCs) embedded on the NE selectively mediate the bidirectional trafficking of macromolecules such as RNAs and proteins between these two cellular compartments. In this book, the authors integrate recent progress on the structure of NPC and the mechanism of nuclear-cytoplasmic transport system in vitro and in vivo.


Nuclear Pore Complexes and Nucleocytoplasmic Transport - Methods

Nuclear Pore Complexes and Nucleocytoplasmic Transport - Methods
Author:
Publisher: Elsevier
Total Pages: 553
Release: 2014-05-20
Genre: Science
ISBN: 0124171788

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Volume 122 of Methods in Cell Biology describes modern tools and techniques used to study nuclear pore complexes and nucleocytoplasmic transport in diverse eukaryotic model systems (including mammalian cells, Xenopus, C. elegans, yeast). The volume enables investigators to analyze nuclear pore complex structure, assembly, and dynamics; to evaluate protein and RNA trafficking through the nuclear envelope; and to design in vivo or in vitro assays appropriate to their research needs. Beyond the study of nuclear pores and transport as such, these protocols will also be helpful to scientists characterizing gene regulation, signal transduction, cell cycle, viral infections, or aging. The NPC being one of the largest multiprotein complexes in the cell, some protocols will also be of interest for people currently characterizing other macromolecular assemblies. This book is thus designed for laboratory use by graduate students, technicians, and researchers in many molecular and cellular disciplines. Describes modern tools and techniques used to study nuclear pore complexes and nucleocytoplasmic transport in diverse eukaryotic model systems (mammalian cells, Xenopus, C. elegans, yeast) Chapters are written by experts in the field Cutting-edge material


Molecular Biology of The Cell

Molecular Biology of The Cell
Author: Bruce Alberts
Publisher:
Total Pages: 0
Release: 2002
Genre: Cytology
ISBN: 9780815332183

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Dengue and Zika: Control and Antiviral Treatment Strategies

Dengue and Zika: Control and Antiviral Treatment Strategies
Author: Rolf Hilgenfeld
Publisher: Springer
Total Pages: 375
Release: 2018-05-29
Genre: Medical
ISBN: 981108727X

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This contributed volume contains 25 chapters from leading international scientists working on dengue and Zika viruses, who came together in Praia do Tofo in Mozambique to discuss the latest developments in the fields of epidemiology, pathogenesis, structural virology, immunology, antiviral drug discovery and development, vaccine efficacy, and mosquito control programs. The meeting venue offered an opportunity to discuss current research on these flaviviruses in an idyllic setting, and also to develop first-hand appreciation of the issues in infectious diseases facing developing countries and of the research gaps in Africa. For readers, who should include basic and clinical researchers in the field and public health professionals, the chapters are organized to provide a comprehensive overview of the various topics in current dengue and Zika virus research. A unique feature of the proceedings of this meeting is the inclusion of the discussions that took place following presentations. These have been transcribed and appended to the end of the relevant chapters, and they form the “salt in the soup” of this book.


The Nucleolus

The Nucleolus
Author: Mark O. J. Olson
Publisher: Springer Science & Business Media
Total Pages: 434
Release: 2011-09-15
Genre: Science
ISBN: 1461405149

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Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest. These new discoveries include both newly-discovered functions and aspects of its conventional role. The Nucleolus is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome biogenesis, and novel functions of the nucleolus.


Between Nucleus and Cytoplasm

Between Nucleus and Cytoplasm
Author: Paul Agutter
Publisher: Springer Science & Business Media
Total Pages: 168
Release: 1990-11-30
Genre: Science
ISBN: 9780412321801

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In the last decade nucleo-cytoplasmic transport has developed into one of the most active areas of research in cell biology and its significance for cell biology as a whole has been recognized. It has led to elucidation of the mechanisms of major cellular functions such as protein synthesis and cellular differentiation. It is also helping to bring about a synthesis of ultrastructural, biochemical, molecular biological and biophysical approaches to the study of cellular organization and function.


Myogenesis

Myogenesis
Author: Grace Pavlath
Publisher: Academic Press
Total Pages: 376
Release: 2011-06-08
Genre: Medical
ISBN: 0123859409

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Myogenesis is the formation of muscular tissue, in particular during embryonic development. This new volume in the "Current topics in Developmental Biology" series covers chapters on such topics as Control of nuclear import during myogenesis, Pathways contributing to fibrosis in skeletal muscle, and Ferlin family members in myogenesis. With an international team of authors, this volume is a must-have addition for researchers and students alike. This new volume in the "Current topics in Developmental Biology" series covers chapters on such topics as Control of nuclear import during myogenesis, Pathways contributing to fibrosis in skeletal muscle, and Ferlin family members in myogenesis With an international team of authors, this volume is a must-have addition for researchers and students alike