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The Immunology of Cardiovascular Homeostasis and Pathology

The Immunology of Cardiovascular Homeostasis and Pathology
Author: Susanne Sattler
Publisher: Springer
Total Pages: 283
Release: 2017-06-30
Genre: Medical
ISBN: 3319576135

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Cardiovascular immunology is a newly emerging research area, investigating the crosstalk between the cardiovascular and the immune system. This crosstalk is evident through (1) crucial immunological capacities and functions of cardiovascular cell types, including cardiomyocytes, fibroblasts, endothelial cells, pericytes and cardiac resident macrophages, (2) the impact of aberrant immune function on the development of cardiovascular disease such as atherosclerosis, direct and indirect immune-mediated heart disease and vasculitis, and (3) the crucial role of the immune system in cardiac repair and regeneration. The Immunology of Cardiovascular Homeostasis and Pathology covers all these aspects of cardiovascular immunology, starting with homeostatic immunological functions of traditional cardiovascular cell types, and moving then to the role of the immune system in cardiovascular pathology and to recent research into targeting the immune system to boost cardiac healing and regeneration.


Handbook of Cardiovascular Immunology

Handbook of Cardiovascular Immunology
Author: Rebbeca Atwell
Publisher: American Medical Publishers
Total Pages: 0
Release: 2023-09-19
Genre: Medical
ISBN: 9781639279647

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Cardiovascular immunology involves the interaction of immune cells with cardiomyocytes, cardiac stromal cells and endothelial cells, which adjust their metabolism for supporting the continuing inflammatory process. The immune system has a crucial role in cardiac homeostasis and illness. If atherothrombotic occlusion disturbs oxygen transport, the downstream hypoxic tissues and cells begin to die within minutes. In case this condition remains untreated, the organism can succumb to stroke or myocardial infarction (MI). The immune system plays a significant role in cardiac growth, composition and function. The immune cells infiltrate the heart during gestation and remain in the myocardium where they perform vital housekeeping functions. A large numbers of immune cells are employed by the heart after a myocardial infarction, or in reaction to infection for promoting recovery, eliminating dying tissue and scavenging pathogens. Immune cells might cause irreparable harm in some cases which leads to heart failure. This book is a compilation of chapters that discuss the most vital aspects in the field of cardiovascular immunology. Through it, we attempt to further enlighten the readers about the new aspects in this field.


How Tobacco Smoke Causes Disease

How Tobacco Smoke Causes Disease
Author:
Publisher:
Total Pages: 728
Release: 2010
Genre: Government publications
ISBN:

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This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.


Anatomy and Physiology

Anatomy and Physiology
Author: J. Gordon Betts
Publisher:
Total Pages: 0
Release: 2013-04-25
Genre:
ISBN: 9781947172807

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Janeway's Immunobiology

Janeway's Immunobiology
Author: Kenneth Murphy
Publisher: Garland Science
Total Pages:
Release: 2010-06-22
Genre: Medical
ISBN: 9780815344575

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The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.


Immune Cells, Inflammation, and Cardiovascular Diseases

Immune Cells, Inflammation, and Cardiovascular Diseases
Author: Shyam S. Bansal
Publisher: CRC Press
Total Pages: 292
Release: 2022-04-19
Genre: Medical
ISBN: 1000570517

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Inflammation, once considered a physiological response to foreign pathogens, is now recognized as a crucial pathological player in the initiation and progression of several chronic diseases, including diabetes, obesity, cancer, Alzheimer’s disease, Parkinson’s disease, and many others. Considering that cardiovascular diseases are a leading cause of death in the United States and worldwide, the identification of critical inflammatory processes is of utmost importance to devising new immune-based therapeutics that can be added to existing regimens. This book provides detailed information on aspects of inflammation and the manner in which immune activation pathways affect the progression of cardiovascular diseases and the repair/regeneration mechanisms of underlying diseased tissues. Key Features Outlines the role that inflammation plays in cardiovascular diseases Describes a paradox – neutralization of cytokines that contribute to cardiovascular disease does not show benefit Summarizes research on a variety of processes and mechanisms contributing to cardiovascular pathology Contributions from an international team of leading cardiologists and cardiovascular immunologists Related Titles Roy, S., et al., eds. Chronic Inflammation: Molecular Pathophysiology, Nutritional and Therapeutic Interventions (ISBN 978-1-138-19955-2) Kong, A-N. T., ed. Inflammation, Oxidative Stress, and Cancer: Dietary Approaches for Cancer Prevention (ISBN 978-1-138-19984-2) Dick, A., et al. Practical Manual of Intraocular Inflammation (ISBN 978-0-367-38720-4)


Molecular Pathology

Molecular Pathology
Author: William B. Coleman
Publisher: Academic Press
Total Pages: 802
Release: 2017-11-09
Genre: Medical
ISBN: 0128027878

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As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase


The ESC Textbook of Vascular Biology

The ESC Textbook of Vascular Biology
Author: Rob Krams
Publisher: Oxford University Press
Total Pages: 347
Release: 2017
Genre: Medical
ISBN: 0198755775

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The ESC Textbook of Vascular Biology is a rich and clearly laid-out guide by leading European scientists providing comprehensive information on vascular physiology, disease, and research.


Pathology Illustrated

Pathology Illustrated
Author: Alasdair D. T. Govan
Publisher:
Total Pages: 843
Release: 1996
Genre: Pathology
ISBN: 9780443056352

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Pathology Illustrated presents both general and systematic pathology in a highly visual style. This format makes the essential information more accessible and memorable.


Metabolic Cardiomyopathy

Metabolic Cardiomyopathy
Author: H. Böhles
Publisher: CRC Press
Total Pages: 188
Release: 2004
Genre: Cardiomyopathy
ISBN: 9783887631048

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During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.