The Immunological Regulation Of Extracellular Vesicles On Chronic Diseases PDF Download
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Author | : Zhiwen Luo |
Publisher | : Frontiers Media SA |
Total Pages | : 146 |
Release | : 2024-06-26 |
Genre | : Medical |
ISBN | : 2832550800 |
Download The immunological regulation of extracellular vesicles on chronic diseases Book in PDF, ePub and Kindle
With the transformation of the human disease spectrum, chronic non-infectious diseases have become the main killer of human health in modern society. The interaction between genes and the environment will cause the body’s immune function to be disordered, thereby affecting the body's homeostasis and causing various chronic non-infectious diseases. It has been revealed that the occurrence and development of most chronic diseases, such as cancer, cardiac disease, diabetes mellitus, autoimmune disease, and neuroimmune disorders, are associated with the dysregulation of the immune system.
Author | : Yaoliang Tang |
Publisher | : Academic Press |
Total Pages | : 287 |
Release | : 2015-09-02 |
Genre | : Science |
ISBN | : 0128004975 |
Download Mesenchymal Stem Cell Derived Exosomes Book in PDF, ePub and Kindle
Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. Introduces the MSC-exosome mediated cell-cell communication Covers the major functional benefits in current MSC-derived exosome studies Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies
Author | : Janette K. Burgess |
Publisher | : Springer Nature |
Total Pages | : 260 |
Release | : 2019-11-23 |
Genre | : Science |
ISBN | : 303029403X |
Download Stem Cell-Based Therapy for Lung Disease Book in PDF, ePub and Kindle
This book presents state-of-the-art pre-clinical models and clinical applications of stem-cell-based therapies applied to different lung diseases, with a special focus on the translation of bench data into clinical studies. Starting with the assumption that abnormal lung tissue repair and regeneration has emerged as the driving force underlying pathogenesis and progression in many lung diseases, it sheds new light on the potential of stem/stromal cells as drivers of repair and sources of reparative factors in the lung. The first part of the book offers an overview of stem cell types and mechanisms involved in lung development, homeostasis, repair and regeneration, and reveals the crucial role of the extracellular matrix within the lung microenvironment. In the second part, leading experts present the latest pre-clinical evidence and clinical applications of stem-cell-based therapies in a wide variety of lung diseases, ranging from COPD and lung fibrosis to other rare lung diseases. The last section discusses stem cell delivery systems and devices, such as aerosolised spray application. This book appeals to pneumologists, stem cell and matrix biologists, as well as bioengeneers with a special interest in regenerative medicine applied to pulmonary diseases.
Author | : Bertrand Kaeffer |
Publisher | : Frontiers Media SA |
Total Pages | : 203 |
Release | : 2023-01-02 |
Genre | : Medical |
ISBN | : 2832510361 |
Download Non-coding RNA in immunotherapies and immune regulation Book in PDF, ePub and Kindle
Author | : Junjie Xiao |
Publisher | : Springer |
Total Pages | : 307 |
Release | : 2017-09-19 |
Genre | : Science |
ISBN | : 9811043973 |
Download Exosomes in Cardiovascular Diseases Book in PDF, ePub and Kindle
The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. It firstly describes the general aspects of exosomes including the definition, formation and secretion of exosomes and highlight their roles as biomarkers and pathological and therapeutic effects in cardiovascular diseases as well. Secondly, basic aspects of exosomes including the purification methods of exosomes, exosomes content, and functional roles of the cardiovascular exosomes are summarized. Thirdly, exosomes as biomarkers of cardiovascular diseases are overviewed including their roles in diagnosis, prognosis and reaction to therapy. Fourthly, pathological effects of exosomes and therapeutic effects of exosomes are highlighted. Finally, future prospects of exosomes in cardiovascular research would be provided. This is an essential reference for researchers working in cell biology and regeneration, as well as clinicians such as cardiologist.
Author | : Dhruv Kumar |
Publisher | : Springer |
Total Pages | : 0 |
Release | : 2021-02-14 |
Genre | : Medical |
ISBN | : 9789811519932 |
Download Cancer Cell Metabolism: A Potential Target for Cancer Therapy Book in PDF, ePub and Kindle
This book illustrates various aspects of cancer cell metabolism, including metabolic regulation in solid tumours vs. non-solid tumours, the molecular pathways involved in its metabolism, and the role of the tumour microenvironment in the regulation of cancer cell metabolism. It summarizes the complexity of cancer cell metabolism in terms of the switch from anaerobic to aerobic glycolysis and how mitochondrial damage promotes aerobic glycolysis in cancer cells. The respective chapters provide the latest information on the metabolic remodelling of cancer cells and elucidate the important role of the signalling pathways in reprogramming of cancer cell metabolism. In addition, the book highlights the role of autophagy in cancer cell metabolism, and how metabolic crosstalk between cancer cells and cancer-associated fibroblasts promotes cancer cell progression. In closing, it summarizes recent advancements in drug development through targeting cancer metabolism.
Author | : Mariusz Z. Ratajczak |
Publisher | : Springer Nature |
Total Pages | : 410 |
Release | : 2020-01-02 |
Genre | : Science |
ISBN | : 3030312062 |
Download Stem Cells Book in PDF, ePub and Kindle
Since different types of stem cells for therapeutic applications have recently been proposed, this timely volume explores various sources of stem cells for tissue and organ regeneration and discusses their advantages and limitations. Also discussed are pros and cons for using embryonic stem cells, induced pluripotent stem cells, and adult stem cells isolated from postnatal tissues. Different types of adult stem cells for therapeutic applications are also reviewed, including hematopoietic stem cells, epidermal stem cells, endothelial progenitors, neural stem cells, mesenchymal stem cells, and very small embryonic-like stem cells. This book also addresses paracrine effects of stem cells in regenerative medicine that are mediated by extracellular microvesicles and soluble secretome. Finally, potential applications of stem cells in cardiology, gastroenterology, neurology, immunotherapy, and aging are presented. This is an ideal book for students and researchers working in the stem cell research field.
Author | : Flavia Bazzoni |
Publisher | : Frontiers Media SA |
Total Pages | : 138 |
Release | : 2020-12-11 |
Genre | : Medical |
ISBN | : 2889662101 |
Download Regulation of Soluble Immune Mediators by Non-Coding RNAs Book in PDF, ePub and Kindle
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author | : Georgia B. Vogelsang |
Publisher | : Cambridge University Press |
Total Pages | : 427 |
Release | : 2009-04-20 |
Genre | : Medical |
ISBN | : 1139478893 |
Download Chronic Graft Versus Host Disease Book in PDF, ePub and Kindle
Chronic graft versus host disease (GVHD) is the most common complication of allogenic bone marrow transplantation. Because of the protracted clinical course of chronic GVHD, transplant centers and hematology/oncology offices are inadequately equipped to manage these immuno-incompetent patients with a multi-system disorder. Practitioners need to be able to recognize and effectively manage chronic GVHD as a late effect of more than half of allogenic transplantations. The text is oriented for the clinician, with chapters covering staging, organ site and system-specific manifestations, treatment options, and supportive care. Drs Georgia B. Vogelsang and Steven Z. Pavletic have been pioneers in the recognition of the multi-organ complexity of this disease and have gathered the input of a variety of subspecialist physicians for this book. This book fills the gap in practical literature on chronic GVHD, providing a comprehensive, up-to-date, and clinically relevant resource for anyone who deals with cancer patients post-transplant.
Author | : Ana Gil De Bona |
Publisher | : BoD – Books on Demand |
Total Pages | : 172 |
Release | : 2020-03-04 |
Genre | : Science |
ISBN | : 1789239435 |
Download Extracellular Vesicles and Their Importance in Human Health Book in PDF, ePub and Kindle
Extracellular vesicle is a wide term that involves many different types of vesicles. Almost all the cell types studied secrete vesicles to the extracellular environment related to cell - cell communication. Extracellular vesicles have been found in different biological fluids, such as blood, milk, saliva, tears, urine, and cerebrospinal fluid. These vesicles transport different molecules, including mRNA, proteins, and lipids, some of them cell type specific that make them ideal biomarkers in both health and disease conditions. However, their contribution to different conditions is not well understood. The aim of this book is to provide an overview of the extracellular vesicles in the human body, how they are internalized, and their participation in several diseases.