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Human Front

Human Front
Author: Ken MacLeod
Publisher: PM Press
Total Pages: 115
Release: 2013-03-25
Genre: Fiction
ISBN: 1604868597

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Ken MacLeod is one of the brightest and most progressive of Britain’s “Hard SF” stars who navigate exciting new futures to the delight of legions of fans around the world. His works combine cutting-edge scientific speculation, socialist and anarchist themes, and a deeply humanistic vision. Described by fans and adversaries alike as a “techno-utopian socialist,” MacLeod thrusts his characters into uncanny encounters that have included AI singularities, divergent human evolution, and posthuman cyborg-resurrection. In his novella The Human Front, a young Scottish guerrilla fighter is drawn into low-intensity sectarian war in a high-intensity dystopian future, and the arrival of an alien intruder (complete with saucer!) calls for new tactics and strange alliances. Its companion piece, “Other Deviations,” first published in this edition, reveals the complex origins of MacLeod’s alternate history. Plus: “The Future Will Happen Here, Too,” in which a Hebridean writer celebrates the landscapes that shaped his work, measures Scotland’s past against humanity’s future, and peers into the eyes of an eel. And Featuring: our irreverent Outspoken Interview, a candid and often cantankerous conversation that showcases our author’s deep erudition and mordant wit.


Heritable Human Genome Editing

Heritable Human Genome Editing
Author: The Royal Society
Publisher: National Academies Press
Total Pages: 239
Release: 2021-01-16
Genre: Medical
ISBN: 0309671132

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Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.


Nature and Human Society

Nature and Human Society
Author: Peter H. Raven
Publisher: National Academies
Total Pages: 648
Release: 2000-03-07
Genre: Technology & Engineering
ISBN:

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From earliest times, human beings have noticed patterns in nature: night and day, tides and lunar cycles, the changing seasons, plant succession, and animal migration. While recognizing patterns conferred great survival advantage, we are now in danger from our own success in multiplying our numbers and altering those patterns for our own purposes. It is imperative that we engage again with the patterns of nature, but this time, with awareness of our impact as a species. How will burgeoning human populations affect the health of ecosystems? Is loss of species simply a regrettable byproduct of human expansion? Or is the planet passing into a new epoch in just a few human generations? Nature and Human Society presents a wide-ranging exploration of these and other fundamental questions about our relationship with the environment. This book features findings, insights, and informed speculations from key figures in the field: E.O. Wilson, Thomas Lovejoy, Peter H. Raven, Gretchen Daily, David Suzuki, Norman Myers, Paul Erlich, Michael Bean, and many others. This volume explores the accelerated extinction of species and what we stand to lose--medicines, energy sources, crop pollination and pest control, the ability of water and soil to renew itself through biological processes, aesthetic and recreational benefits--and how these losses may be felt locally and acutely. What are the specific threats to biodiversity? The book explores human population growth, the homogenization of biota as a result in tourism and trade, and other factors, including the social influences of law, religious belief, and public education. Do we have the tools to protect biodiversity? The book looks at molecular genetics, satellite data, tools borrowed from medicine, and other scientific techniques to firm up our grasp of important processes in biology and earth science, including the "new" science of conservation biology. Nature and Human Society helps us renew our understanding and appreciation for natural patterns, with surprising details about microorganisms, nematodes, and other overlooked forms of life: their numbers, pervasiveness, and importance to the health of the soil, water, and air and to a host of human endeavors. This book will be of value to anyone who believes that the world's gross natural product is as important as the world's gross national product.


Mapping and Sequencing the Human Genome

Mapping and Sequencing the Human Genome
Author: National Research Council
Publisher: National Academies Press
Total Pages: 128
Release: 1988-01-01
Genre: Science
ISBN: 0309038405

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There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.


The Human Front

The Human Front
Author: Ken MacLeod
Publisher: PM Press
Total Pages: 112
Release: 2013
Genre: Fiction
ISBN: 9781604863956

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As a world war rages in an uncertain future, young teen guerilla fighter John Matheson must shift his tactics and alliances when an alien species arrives. Includes two essays and an interview with the author.


Human Genome Editing

Human Genome Editing
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 329
Release: 2017-08-13
Genre: Medical
ISBN: 0309452880

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Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.


To Err Is Human

To Err Is Human
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 312
Release: 2000-03-01
Genre: Medical
ISBN: 0309068371

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Experts estimate that as many as 98,000 people die in any given year from medical errors that occur in hospitals. That's more than die from motor vehicle accidents, breast cancer, or AIDSâ€"three causes that receive far more public attention. Indeed, more people die annually from medication errors than from workplace injuries. Add the financial cost to the human tragedy, and medical error easily rises to the top ranks of urgent, widespread public problems. To Err Is Human breaks the silence that has surrounded medical errors and their consequenceâ€"but not by pointing fingers at caring health care professionals who make honest mistakes. After all, to err is human. Instead, this book sets forth a national agendaâ€"with state and local implicationsâ€"for reducing medical errors and improving patient safety through the design of a safer health system. This volume reveals the often startling statistics of medical error and the disparity between the incidence of error and public perception of it, given many patients' expectations that the medical profession always performs perfectly. A careful examination is made of how the surrounding forces of legislation, regulation, and market activity influence the quality of care provided by health care organizations and then looks at their handling of medical mistakes. Using a detailed case study, the book reviews the current understanding of why these mistakes happen. A key theme is that legitimate liability concerns discourage reporting of errorsâ€"which begs the question, "How can we learn from our mistakes?" Balancing regulatory versus market-based initiatives and public versus private efforts, the Institute of Medicine presents wide-ranging recommendations for improving patient safety, in the areas of leadership, improved data collection and analysis, and development of effective systems at the level of direct patient care. To Err Is Human asserts that the problem is not bad people in health careâ€"it is that good people are working in bad systems that need to be made safer. Comprehensive and straightforward, this book offers a clear prescription for raising the level of patient safety in American health care. It also explains how patients themselves can influence the quality of care that they receive once they check into the hospital. This book will be vitally important to federal, state, and local health policy makers and regulators, health professional licensing officials, hospital administrators, medical educators and students, health caregivers, health journalists, patient advocatesâ€"as well as patients themselves. First in a series of publications from the Quality of Health Care in America, a project initiated by the Institute of Medicine


Front-End Vision and Multi-Scale Image Analysis

Front-End Vision and Multi-Scale Image Analysis
Author: Bart M. Haar Romeny
Publisher: Springer Science & Business Media
Total Pages: 470
Release: 2008-10-24
Genre: Computers
ISBN: 140208840X

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Many approaches have been proposed to solve the problem of finding the optic flow field of an image sequence. Three major classes of optic flow computation techniques can discriminated (see for a good overview Beauchemin and Barron IBeauchemin19951): gradient based (or differential) methods; phase based (or frequency domain) methods; correlation based (or area) methods; feature point (or sparse data) tracking methods; In this chapter we compute the optic flow as a dense optic flow field with a multi scale differential method. The method, originally proposed by Florack and Nielsen [Florack1998a] is known as the Multiscale Optic Flow Constrain Equation (MOFCE). This is a scale space version of the well known computer vision implementation of the optic flow constraint equation, as originally proposed by Horn and Schunck [Horn1981]. This scale space variation, as usual, consists of the introduction of the aperture of the observation in the process. The application to stereo has been described by Maas et al. [Maas 1995a, Maas 1996a]. Of course, difficulties arise when structure emerges or disappears, such as with occlusion, cloud formation etc. Then knowledge is needed about the processes and objects involved. In this chapter we focus on the scale space approach to the local measurement of optic flow, as we may expect the visual front end to do. 17. 2 Motion detection with pairs of receptive fields As a biologically motivated start, we begin with discussing some neurophysiological findings in the visual system with respect to motion detection.


Understanding Climate's Influence on Human Evolution

Understanding Climate's Influence on Human Evolution
Author: National Research Council
Publisher: National Academies Press
Total Pages: 128
Release: 2010-04-17
Genre: Science
ISBN: 0309148383

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The hominin fossil record documents a history of critical evolutionary events that have ultimately shaped and defined what it means to be human, including the origins of bipedalism; the emergence of our genus Homo; the first use of stone tools; increases in brain size; and the emergence of Homo sapiens, tools, and culture. The Earth's geological record suggests that some evolutionary events were coincident with substantial changes in African and Eurasian climate, raising the possibility that critical junctures in human evolution and behavioral development may have been affected by the environmental characteristics of the areas where hominins evolved. Understanding Climate's Change on Human Evolution explores the opportunities of using scientific research to improve our understanding of how climate may have helped shape our species. Improved climate records for specific regions will be required before it is possible to evaluate how critical resources for hominins, especially water and vegetation, would have been distributed on the landscape during key intervals of hominin history. Existing records contain substantial temporal gaps. The book's initiatives are presented in two major research themes: first, determining the impacts of climate change and climate variability on human evolution and dispersal; and second, integrating climate modeling, environmental records, and biotic responses. Understanding Climate's Change on Human Evolution suggests a new scientific program for international climate and human evolution studies that involve an exploration initiative to locate new fossil sites and to broaden the geographic and temporal sampling of the fossil and archeological record; a comprehensive and integrative scientific drilling program in lakes, lake bed outcrops, and ocean basins surrounding the regions where hominins evolved and a major investment in climate modeling experiments for key time intervals and regions that are critical to understanding human evolution.


The Human Figure

The Human Figure
Author: John Henry Vanderpoel
Publisher:
Total Pages: 184
Release: 1908
Genre: Anatomy, Artistic
ISBN:

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