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The Guinea Pig Model

The Guinea Pig Model
Author: Viviana Parreño
Publisher: CRC Press
Total Pages: 118
Release: 2023-04-10
Genre: Science
ISBN: 1000850633

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This book summarizes the development and statistical validation of a guinea pig model as an alternative for potency testing of the viral antigens included in combined vaccines applied in cattle to control the respiratory, reproductive, and neonatal calf diarrhea syndromes. The model allows, in one serum sample, to test the vaccine quality for all the viral antigens included in aqueous as well as in oil-adjuvanted formulations of bovine vaccines. The methodology proposed for the control of bovine herpes virus, parainfluenza, and rotavirus were recommended by CAMEVET as guidelines for the 30 countries in the forum, including the US. Key Features Reviews combined vaccines used for cattle Summarizes animal models used for vaccine testing Focuses on bovine herpesviruses, rotaviruses, parainfluenza, and bovine viral diarrhea virus Provides guidance on the effectiveness of the Guinea Pig model for testing vaccine immunogenicity


Tuberculosis

Tuberculosis
Author: Barry R. Bloom
Publisher:
Total Pages: 664
Release: 1994
Genre: Medical
ISBN:

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The authors discuss fundamental questions about the biology, genetics, mechanisms of pathogenicity, mechanisms of resistance, and drug development strategies that are likely to provide important new knowledge about TB and new interventions to prevent and treat this disease.


A Guinea Pig's History of Biology

A Guinea Pig's History of Biology
Author: Jim Endersby
Publisher: Harvard University Press
Total Pages: 544
Release: 2007
Genre: Science
ISBN: 9780674027138

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"Endless forms most beautiful and most wonderful have been, and are being, evolved," Darwin famously concluded The Origin of Species, and for confirmation we look to...the guinea pig? How this curious creature and others as humble (and as fast-breeding) have helped unlock the mystery of inheritance is the unlikely story Jim Endersby tells in this book. Biology today promises everything from better foods or cures for common diseases to the alarming prospect of redesigning life itself. Looking at the organisms that have made all this possible gives us a new way of understanding how we got here--and perhaps of thinking about where we're going. Instead of a history of which great scientists had which great ideas, this story of passionflowers and hawkweeds, of zebra fish and viruses, offers a bird's (or rodent's) eye view of the work that makes science possible. Mixing the celebrities of genetics, like the fruit fly, with forgotten players such as the evening primrose, the book follows the unfolding history of biological inheritance from Aristotle's search for the "universal, absolute truth of fishiness" to the apparently absurd speculations of eighteenth-century natural philosophers to the spectacular findings of our day--which may prove to be the absurdities of tomorrow. The result is a quirky, enlightening, and thoroughly engaging perspective on the history of heredity and genetics, tracing the slow, uncertain path--complete with entertaining diversions and dead ends--that led us from the ancient world's understanding of inheritance to modern genetics.


Nutrient Requirements of Laboratory Animals,

Nutrient Requirements of Laboratory Animals,
Author: National Research Council
Publisher: National Academies Press
Total Pages: 188
Release: 1995-02-01
Genre: Science
ISBN: 0309051266

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In the years since the third edition of this indispensable reference was published, a great deal has been learned about the nutritional requirements of common laboratory species: rat, mouse, guinea pig, hamster, gerbil, and vole. The Fourth Revised Edition presents the current expert understanding of the lipid, carbohydrate, protein, mineral, vitamin, and other nutritional needs of these animals. The extensive use of tables provides easy access to a wealth of comprehensive data and resource information. The volume also provides an expanded background discussion of general dietary considerations. In addition to a more user-friendly organization, new features in this edition include: A significantly expanded section on dietary requirements for rats, reporting substantial new findings. A new section on nutrients that are not required but that may produce beneficial results. New information on growth and reproductive performance among the most commonly used strains of rats and mice and on several hamster species. An expanded discussion of diet formulation and preparationâ€"including sample diets of both purified and natural ingredients. New information on mineral deficiency and toxicity, including warning signs. This authoritative resource will be important to researchers, laboratory technicians, and manufacturers of laboratory animal feed.


Animal Biotechnology

Animal Biotechnology
Author: Ashish S. Verma
Publisher: Academic Press
Total Pages: 685
Release: 2013-11-04
Genre: Science
ISBN: 0123914345

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Animal Biotechnology introduces applications of animal biotechnology and implications for human health and welfare. It begins with an introduction to animal cell cultures and genome sequencing analysis and provides readers with a review of available cell and molecular tools. Topics here include the use of transgenic animal models, tissue engineering, nanobiotechnology, and proteomics. The book then delivers in-depth examples of applications in human health and prospects for the future, including cytogenetics and molecular genetics, xenografts, and treatment of HIV and cancers. All this is complemented by a discussion of the ethical and safety considerations in the field.Animal biotechnology is a broad field encompassing the polarities of fundamental and applied research, including molecular modeling, gene manipulation, development of diagnostics and vaccines, and manipulation of tissue. Given the tools that are currently available and the translational potential for these studies, animal biotechnology has become one of the most essential subjects for those studying life sciences. Highlights the latest biomedical applications of genetically modified and cloned animals with a focus on cancer and infectious diseases Provides firsthand accounts of the use of biotechnology tools, including molecular markers, stem cells, and tissue engineering


Buruli Ulcer

Buruli Ulcer
Author: Gerd Pluschke
Publisher: Springer
Total Pages: 287
Release: 2019-04-29
Genre: Medical
ISBN: 3030111148

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A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans.


The Biology of the Guinea Pig

The Biology of the Guinea Pig
Author: Joseph E. Wagner
Publisher: Academic Press
Total Pages: 330
Release: 2014-04-25
Genre: Science
ISBN: 148328932X

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Approx.317 pages


Sourcebook of Models for Biomedical Research

Sourcebook of Models for Biomedical Research
Author: P. Michael Conn
Publisher: Springer Science & Business Media
Total Pages: 756
Release: 2008-03-07
Genre: Medical
ISBN: 1597452858

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The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.


Immunobiology of Transfer Factor

Immunobiology of Transfer Factor
Author: Charles H. Kirkpatrick
Publisher: Academic Press
Total Pages: 462
Release: 2014-06-28
Genre: Medical
ISBN: 1483277682

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Immunobiology of Transfer Factor compiles research papers presented at the Fourth International Transfer Factor Workshop, held at the Given Institute of Pathobiology in Aspen, Colorado, on October 3-6, 1982. This book focuses on the immunologic effects of transfer factor, which are supported by in vitro and in vivo experiments that indicate immunologically specific interactions between transfer factor and antigens. The topics include the selective removal of transfer factor activity with antigen, antigen-specific suppressor factor in human leukocyte dialysates, and specific suppressor dialysates from mice. The kinetics of immune response and production of transfer factor in bovine, dialyzable leukocyte extracts in pulmonary diseases, and mechanisms of action of human transfer factor are also elaborated. This compilation is suitable for microbiologists, immunologists, and specialists researching on transfer factor.


Companion Animal Care and Welfare

Companion Animal Care and Welfare
Author: James Yeates
Publisher: John Wiley & Sons
Total Pages: 517
Release: 2019-02-04
Genre: Medical
ISBN: 1118688791

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Companion Animal Care and Welfare: The UFAW Companion Animal Handbook presents a comprehensive, accessible and practical reference for all parties seeking information about the proper care of companion animals. Identifies the needs of companion animals, explains how we know these needs, and gives scientifically-backed advice on how to meet these needs Promotes the most humane treatment and best possible care of our companion animals Addresses controversial issues such as selective breeding, companion animal showing, the keeping of exotic species, and the international pet trade Covers the husbandry and care of all major companion animal species, including mammals, birds, fish, reptiles and amphibians