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The Global HIV Epidemics Among People Who Inject Drugs

The Global HIV Epidemics Among People Who Inject Drugs
Author: Arin Dutta
Publisher: World Bank Publications
Total Pages: 139
Release: 2012-12-13
Genre: Medical
ISBN: 0821397761

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This publication addresses research questions related to an increase in the levels of access and utilization for four key interventions that have the potential to significantly reduce HIV infections among People Who Inject Drugs (PWID) and their sexual and injecting partners, and hence morbidity and mortality in low and middle-income countries (LMIC). These interventions are drawn from nine consensus interventions that comprise a 'comprehensive package' for PWID. The four interventions are: Needle and Syringe Programs (NSP), Medically Assisted Therapy (MAT), HIV Counseling and Testing (HCT), and Antiretroviral Therapy (ART). The book summarizes the results from several recent reviews of studies related to the effectiveness of the four key interventions in reducing risky behaviors in the context of transmitting or acquiring HIV infection. Overall, the four key interventions have strong effects on the risk of HIV infection among PWID via different pathways, and this determination is included in the documents proposing the comprehensive package of interventions. In order to attain the greatest effect from these interventions, structural issues must be addressed, especially the removal of punitive policies targeting PWID in many countries. The scientific evidence presented here, the public health rationale, and the human rights imperatives are all in accord: we can and must do better for PWID. The available tools are evidence-based, right affirming, and cost effective. What are required now are political will and a global consensus that this critical component of global HIV can no longer be ignored and under-resourced.


Preventing HIV Infection Among Injecting Drug Users in High-Risk Countries

Preventing HIV Infection Among Injecting Drug Users in High-Risk Countries
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 298
Release: 2006-12-20
Genre: Medical
ISBN: 0309102804

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Drug dependence is a complex, chronic, relapsing condition that is often accompanied by severe health, psychological, economic, legal, and social consequences. Injecting drug users are particularly vulnerable to HIV and other bloodborne infections (such as hepatitis C) as a result of sharing contaminated injecting equipment. All drug-dependent individuals, including injecting drug users (IDUs), may be at increased risk of HIV infection because of high-risk sexual behaviors. There are an estimated 13.2 million injecting drug users (IDUs) world-wide-78 percent of whom live in developing or transitional countries. The sharing of contaminated injecting equipment has become a major driving force of the global AIDS epidemic and is the primary mode of HIV transmission in many countries. In some cases, epidemics initially fueled by the sharing of contaminated injecting equipment are spreading through sexual transmission from IDUs to non-injecting populations, and through perinatal transmission to newborns. Reversing the rise of HIV infections among IDUs has thus become an urgent global public health challenge-one that remains largely unmet. In response to this challenge, the Institute of Medicine convened a public workshop in Geneva in December 2005 to gather information from experts on IDU-driven HIV epidemics in the most affected regions of the world with an emphasis on countries throughout Eastern Europe, the Commonwealth of Independent States, and significant parts of Asia. Experts from other regions also provided information on their experiences in preventing HIV infection among IDUs. This report provides a summary of the workshop discussions. Preventing HIV Infection among Injecting Drug Users in High Risk Countries describes the evidence on the intermediate outcomes of drug-related risk and sex-related risk prior to examining the impact on HIV transmission. This report focuses on programs that are designed to prevent the transmission of HIV among injecting drug users. These programs range from efforts to curtail non-medical drug use to those that encourage reduction in high-risk behavior among drug users. Although the report focuses on HIV prevention for IDUs in high-risk countries, the Committee considered evidence from countries around the world. The findings and recommendations of this report are also applicable to countries where injecting drug use is not the primary driver, but in which injection drug use is nevertheless associated with significant HIV transmission.


Disease Control Priorities, Third Edition (Volume 6)

Disease Control Priorities, Third Edition (Volume 6)
Author: King K. Holmes
Publisher: World Bank Publications
Total Pages: 1027
Release: 2017-11-06
Genre: Medical
ISBN: 1464805253

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Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.


Preventing HIV Transmission

Preventing HIV Transmission
Author: National Research Council and Institute of Medicine
Publisher: National Academies Press
Total Pages: 352
Release: 1995-09-14
Genre: Medical
ISBN: 0309176212

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This volume addresses the interface of two major national problems: the epidemic of HIV-AIDS and the widespread use of illegal injection drugs. Should communities have the option of giving drug users sterile needles or bleach for cleaning needs in order to reduce the spread of HIV? Does needle distribution worsen the drug problem, as opponents of such programs argue? Do they reduce the spread of other serious diseases, such as hepatitis? Do they result in more used needles being carelessly discarded in the community? The panel takes a critical look at the available data on needle exchange and bleach distribution programs, reaches conclusions about their efficacy, and offers concrete recommendations for public policy to reduce the spread of HIV/AIDS. The book includes current knowledge about the epidemiologies of HIV/AIDS and injection drug use; characteristics of needle exchange and bleach distribution programs and views on those programs from diverse community groups; and a discussion of laws designed to control possession of needles, their impact on needle sharing among injection drug users, and their implications for needle exchange programs.


The Global HIV Epidemics among Sex Workers

The Global HIV Epidemics among Sex Workers
Author: Deanna Kerrigan
Publisher: World Bank Publications
Total Pages: 344
Release: 2012-12-01
Genre: Medical
ISBN: 0821397753

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A global economic analysis of HIV infection amongst sex workers, finding that evidence based and rights affirming interventions are not implemented to the level that their efficacy warrants, and that doing so at scale would be cost effective and deliver significant returns on investment.


HIV Epidemics in the European Region

HIV Epidemics in the European Region
Author: Lucy Platt
Publisher: World Bank Publications
Total Pages: 369
Release: 2015-02-12
Genre: Medical
ISBN: 1464803897

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This report describes the dynamics of HIV epidemics among vulnerable and high risk populations in the European region, in particular people who inject drugs, sex workers, and men who have sex with men. It aims to inform future HIV responses and guide HIV prevention surveillance and research.


Behaviours, Networks, and Sequences

Behaviours, Networks, and Sequences
Author: Laura Hilary Thompson
Publisher:
Total Pages: 0
Release: 2020
Genre:
ISBN:

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The estimated overall HIV prevalence among people who inject drugs (PWID) in Pakistan is 21%, with significant geographic heterogeneity. This study explored whether disparate types of evidence about HIV epidemics among PWID in five different cities across Pakistan may be triangulated using a social ecological framework to achieve new insights into what is shaping local epidemics. Evidence that capture HIV risk factors at the level of the 1) characteristics and behaviours of PWID, 2) social organization of PWID, and 3) broader macrosocial context was included. Questionnaire data and dried blood spots were collected from 1,439 PWID in 2014/2015. HIV testing and sequencing of the HIV pol gene was conducted. Networks connecting participants who had named the same injection locations were constructed. Network-level exposures, k-core, and degree centrality were calculated, and dot density maps of injection locations were generated. Phylogenetic data derived from HIV sequences were used to identify molecular clusters. Demographic, behavioural, and network variables were tested for associations with HIV infection. In Hyderabad, use of professional injectors, network position, and network exposures to others who use professional injectors were associated with HIV. In Karachi, injecting at places with a greater proportion of other people who were HIV positive was associated with HIV. In Larkana, injection by a professional injector was protective against HIV, and it is believed that HIV prevention programs may have engaged professional injectors in this city. In the highly dense network context of Peshawar, with scarce HIV prevention services, molecular results revealed a large cluster of 52 individuals who likely became infected just prior to sampling. Although the HIV prevalence among PWID was relatively low in Quetta, use of a professional injector was common and being connected to a network component with a large proportion of other people who received help injecting was associated with HIV infection. The results of this study indicated that generally high levels of risk behaviours and poor access to HIV prevention programs. Local network structures and the practices of professional injectors within networks influence individual risk and shape HIV epidemics locally. The configuration and relevance of city-specific factors were likely highly influenced by the local social economic and security environments.


Drug Injecting and HIV Infection

Drug Injecting and HIV Infection
Author: Andrew Ball
Publisher: Routledge
Total Pages: 313
Release: 2003-09-02
Genre: Health & Fitness
ISBN: 1135359547

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This is a comparative international study of drug injecting behaviour and HIV infection based on the World Health Organization's study of 13 cities as disparate as Athens, Bangkok, Glasgow and Rio de Janeiro.


The Social Impact of AIDS in the United States

The Social Impact of AIDS in the United States
Author: National Research Council
Publisher: National Academies Press
Total Pages: 337
Release: 1993-02-01
Genre: Medical
ISBN: 0309046289

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Europe's "Black Death" contributed to the rise of nation states, mercantile economies, and even the Reformation. Will the AIDS epidemic have similar dramatic effects on the social and political landscape of the twenty-first century? This readable volume looks at the impact of AIDS since its emergence and suggests its effects in the next decade, when a million or more Americans will likely die of the disease. The Social Impact of AIDS in the United States addresses some of the most sensitive and controversial issues in the public debate over AIDS. This landmark book explores how AIDS has affected fundamental policies and practices in our major institutions, examining: How America's major religious organizations have dealt with sometimes conflicting values: the imperative of care for the sick versus traditional views of homosexuality and drug use. Hotly debated public health measures, such as HIV antibody testing and screening, tracing of sexual contacts, and quarantine. The potential risk of HIV infection to and from health care workers. How AIDS activists have brought about major change in the way new drugs are brought to the marketplace. The impact of AIDS on community-based organizations, from volunteers caring for individuals to the highly political ACT-UP organization. Coping with HIV infection in prisons. Two case studies shed light on HIV and the family relationship. One reports on some efforts to gain legal recognition for nonmarital relationships, and the other examines foster care programs for newborns with the HIV virus. A case study of New York City details how selected institutions interact to give what may be a picture of AIDS in the future. This clear and comprehensive presentation will be of interest to anyone concerned about AIDS and its impact on the country: health professionals, sociologists, psychologists, advocates for at-risk populations, and interested individuals.


AIDS Epidemic Update, December 2006

AIDS Epidemic Update, December 2006
Author: Joint United Nations Programme on HIV/AIDS.
Publisher: World Health Organization
Total Pages: 97
Release: 2007-03-07
Genre: Medical
ISBN: 9291735426

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This annual update reports on developments in the global HIV/AIDS epidemic and draws on the most recent data available to give global and regional estimates of its scope and human toll. Despite promising developments in global efforts to address the AIDS epidemic, including increased access to effective treatment and prevention programmes, the number of people living with HIV continues to grow, as does the number of deaths due to AIDS. Findings for 2006 include: the total number of people living with HIV is estimated at 39.5 million, 4.3 million new cases during the year and an estimated 2.9 million deaths. Sub-Saharan Africa continues to bear the brunt of the global epidemic with 63 per cent of all adults and children with HIV globally and with its epicentre in southern Africa. In the past two years, the number of people living with HIV increased in every region in the world, with the most striking increases in East Asia, Eastern Europe and Central Asia, where the number of people living with HIV in 2006 was over 21 per cent higher than in 2004.