The Gene Ontology Handbook PDF Download
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| Author | : Christophe Dessimoz |
| Publisher | : |
| Total Pages | : 298 |
| Release | : 2020-10-08 |
| Genre | : Science |
| ISBN | : 9781013267703 |
Download The Gene Ontology Handbook Book in PDF, ePub and Kindle
This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
| Author | : Christophe Dessimoz |
| Publisher | : |
| Total Pages | : 298 |
| Release | : 2020-10-08 |
| Genre | : Science |
| ISBN | : 9781013267710 |
Download The Gene Ontology Handbook Book in PDF, ePub and Kindle
This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
| Author | : Paige Hill |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2023-09-26 |
| Genre | : Science |
| ISBN | : 9781647403805 |
Download Gene Ontology: A Resource for Analysis and Interpretation of Biological Database Book in PDF, ePub and Kindle
The gene ontology (GO) is a bioinformatics project which aims to merge the representation of gene and characteristics of gene product in all species. It is a thorough and updated compilation of biological information that is utilized as a resource for computational representation of the most recent scientific data available concerning coding as well as non-coding functions of genes. High-throughput biological datasets can be interpreted and analyzed using the GO resource. The goal of the GO analysis is to pinpoint the molecular functions, biological processes and cellular locations of the genes. It utilizes markup language in order to make the genetic data and curated attributes of gene products readable by machine, in a manner which is integrated across all species. This book provides comprehensive insights on gene ontology. It aims to shed light on some of the unexplored aspects of this subject. Those in search of information to further their knowledge will be greatly assisted by this book.
| Author | : Rajesh K. Gaur |
| Publisher | : CRC Press |
| Total Pages | : 440 |
| Release | : 2009-04-27 |
| Genre | : Science |
| ISBN | : 1420008706 |
Download Regulation of Gene Expression by Small RNAs Book in PDF, ePub and Kindle
New Findings Revolutionize Concepts of Gene FunctionEndogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria. Furthermore, it's been shown that microRNAs acting as cellular rheostats have the ability to modulate gene expression. In higher eukaryotes, microRNAs may regulate as much as 50 p
| Author | : Mourad Elloumi |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1192 |
| Release | : 2013-12-24 |
| Genre | : Computers |
| ISBN | : 1118617118 |
Download Biological Knowledge Discovery Handbook Book in PDF, ePub and Kindle
The first comprehensive overview of preprocessing, mining,and postprocessing of biological data Molecular biology is undergoing exponential growth in both thevolume and complexity of biological data—and knowledgediscovery offers the capacity to automate complex search and dataanalysis tasks. This book presents a vast overview of the mostrecent developments on techniques and approaches in the field ofbiological knowledge discovery and data mining (KDD)—providingin-depth fundamental and technical field information on the mostimportant topics encountered. Written by top experts, Biological Knowledge DiscoveryHandbook: Preprocessing, Mining, and Postprocessing of BiologicalData covers the three main phases of knowledge discovery (datapreprocessing, data processing—also known as datamining—and data postprocessing) and analyzes both verificationsystems and discovery systems. BIOLOGICAL DATA PREPROCESSING Part A: Biological Data Management Part B: Biological Data Modeling Part C: Biological Feature Extraction Part D Biological Feature Selection BIOLOGICAL DATA MINING Part E: Regression Analysis of Biological Data Part F Biological Data Clustering Part G: Biological Data Classification Part H: Association Rules Learning from Biological Data Part I: Text Mining and Application to Biological Data Part J: High-Performance Computing for Biological DataMining Combining sound theory with practical applications in molecularbiology, Biological Knowledge Discovery Handbook is idealfor courses in bioinformatics and biological KDD as well as forpractitioners and professional researchers in computer science,life science, and mathematics.
| Author | : Miguel-angel Sicilia |
| Publisher | : World Scientific |
| Total Pages | : 579 |
| Release | : 2013-12-17 |
| Genre | : Computers |
| ISBN | : 9814590355 |
Download Handbook Of Metadata, Semantics And Ontologies Book in PDF, ePub and Kindle
Metadata research has emerged as a discipline cross-cutting many domains, focused on the provision of distributed descriptions (often called annotations) to Web resources or applications. Such associated descriptions are supposed to serve as a foundation for advanced services in many application areas, including search and location, personalization, federation of repositories and automated delivery of information. Indeed, the Semantic Web is in itself a concrete technological framework for ontology-based metadata. For example, Web-based social networking requires metadata describing people and their interrelations, and large databases with biological information use complex and detailed metadata schemas for more precise and informed search strategies.There is a wide diversity in the languages and idioms used for providing meta-descriptions, from simple structured text in metadata schemas to formal annotations using ontologies, and the technologies for storing, sharing and exploiting meta-descriptions are also diverse and evolve rapidly. In addition, there is a proliferation of schemas and standards related to metadata, resulting in a complex and moving technological landscape — hence, the need for specialized knowledge and skills in this area.The Handbook of Metadata, Semantics and Ontologies is intended as an authoritative reference for students, practitioners and researchers, serving as a roadmap for the variety of metadata schemas and ontologies available in a number of key domain areas, including culture, biology, education, healthcare, engineering and library science.
| Author | : Steffen Staab |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 661 |
| Release | : 2013-04-17 |
| Genre | : Computers |
| ISBN | : 3540247505 |
Download Handbook on Ontologies Book in PDF, ePub and Kindle
An ontology is a description (like a formal specification of a program) of concepts and relationships that can exist for an agent or a community of agents. The concept is important for the purpose of enabling knowledge sharing and reuse. The Handbook on Ontologies provides a comprehensive overview of the current status and future prospectives of the field of ontologies. The handbook demonstrates standards that have been created recently, it surveys methods that have been developed and it shows how to bring both into practice of ontology infrastructures and applications that are the best of their kind.
| Author | : Michael Feathers |
| Publisher | : Prentice Hall Professional |
| Total Pages | : 457 |
| Release | : 2004-09-22 |
| Genre | : Computers |
| ISBN | : 0132931753 |
Download Working Effectively with Legacy Code Book in PDF, ePub and Kindle
Get more out of your legacy systems: more performance, functionality, reliability, and manageability Is your code easy to change? Can you get nearly instantaneous feedback when you do change it? Do you understand it? If the answer to any of these questions is no, you have legacy code, and it is draining time and money away from your development efforts. In this book, Michael Feathers offers start-to-finish strategies for working more effectively with large, untested legacy code bases. This book draws on material Michael created for his renowned Object Mentor seminars: techniques Michael has used in mentoring to help hundreds of developers, technical managers, and testers bring their legacy systems under control. The topics covered include Understanding the mechanics of software change: adding features, fixing bugs, improving design, optimizing performance Getting legacy code into a test harness Writing tests that protect you against introducing new problems Techniques that can be used with any language or platform—with examples in Java, C++, C, and C# Accurately identifying where code changes need to be made Coping with legacy systems that aren't object-oriented Handling applications that don't seem to have any structure This book also includes a catalog of twenty-four dependency-breaking techniques that help you work with program elements in isolation and make safer changes.
| Author | : Theodore P. Beauchaine |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 545 |
| Release | : 2015-10-29 |
| Genre | : Medical |
| ISBN | : 0199324670 |
Download The Oxford Handbook of Externalizing Spectrum Disorders Book in PDF, ePub and Kindle
The Oxford Handbook of Externalizing Spectrum Disorders is the first book of its kind to capture the developmental psychopathology of externalizing spectrum disorders by examining causal factors across levels of analysis and developmental epochs, while departing from the categorical perspective.
| Author | : Robert Arp |
| Publisher | : MIT Press |
| Total Pages | : 245 |
| Release | : 2015-08-28 |
| Genre | : Science |
| ISBN | : 026232959X |
Download Building Ontologies with Basic Formal Ontology Book in PDF, ePub and Kindle
An introduction to the field of applied ontology with examples derived particularly from biomedicine, covering theoretical components, design practices, and practical applications. In the era of “big data,” science is increasingly information driven, and the potential for computers to store, manage, and integrate massive amounts of data has given rise to such new disciplinary fields as biomedical informatics. Applied ontology offers a strategy for the organization of scientific information in computer-tractable form, drawing on concepts not only from computer and information science but also from linguistics, logic, and philosophy. This book provides an introduction to the field of applied ontology that is of particular relevance to biomedicine, covering theoretical components of ontologies, best practices for ontology design, and examples of biomedical ontologies in use. After defining an ontology as a representation of the types of entities in a given domain, the book distinguishes between different kinds of ontologies and taxonomies, and shows how applied ontology draws on more traditional ideas from metaphysics. It presents the core features of the Basic Formal Ontology (BFO), now used by over one hundred ontology projects around the world, and offers examples of domain ontologies that utilize BFO. The book also describes Web Ontology Language (OWL), a common framework for Semantic Web technologies. Throughout, the book provides concrete recommendations for the design and construction of domain ontologies.
