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The Fischer Indole Synthesis

The Fischer Indole Synthesis
Author: Brian Robinson
Publisher:
Total Pages: 952
Release: 1982
Genre: Science
ISBN:

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A comprehensive survey of the Fischer indole synthesis. Emphasizes three main features of the reaction, its development, the clarification of its mechanism, and the utilization of it and its extensions in the synthetic process. Covers the investigations of the reaction from its discovery in 1883 through the last published report in 1981.


Indole Ring Synthesis

Indole Ring Synthesis
Author: Gordon W. Gribble
Publisher: John Wiley & Sons
Total Pages: 704
Release: 2016-08-08
Genre: Science
ISBN: 0470512180

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Of the myriad of heterocycles known to man, the indole ring stands foremost for its remarkably versatile chemistry, its enormous range of biological activities, and its ubiquity in the terrestrial and marine environments. The indole ring continues to be discovered in natural products and to be employed in man-made pharmaceuticals and other materials. Given the enormous resurgence in indole ring synthesis over the past decade — highlighted by the power of transition metal catalysis — this authoritative guide addresses the need for a comprehensive presentation of the myriad of methods for constructing the indole ring, from the ancient to the modern, and from the obscure to the well-known. Following presentation of the classic indole ring syntheses and many newer methods, coverage continues with indole ring syntheses via pyrroles, indolines, oxindoles, isatins, radical and photochemical reactions, aryne cycloadditions. This extensive volume concludes with the modern transition metal–catalyzed indole ring syntheses that utilize copper, palladium, rhodium, gold, ruthenium, platinum, and other metals to fashion the indole ring Indole Ring Synthesis is a comprehensive, authoritative and up-to-date guide to the synthesis of this important heterocycle for organic chemists, pharmaceutical researchers and those interested in the chemistry of natural products.


Organic Chemistry: 100 Must-Know Mechanisms

Organic Chemistry: 100 Must-Know Mechanisms
Author: Roman Valiulin
Publisher: Walter de Gruyter GmbH & Co KG
Total Pages: 249
Release: 2020-04-20
Genre: Science
ISBN: 3110608375

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This book summarizes 100 essential mechanisms in organic chemistry ranging from classical such as the Reformatsky Reaction from 1887 to recently elucidated mechanism such as the copper(I)-catalyzed alkyne-azide cycloaddition. The reactions are easy to grasp, well-illustrated and underpinned with explanations and additional information.


Name Reactions

Name Reactions
Author: Jie Jack Li
Publisher: Springer Science & Business Media
Total Pages: 670
Release: 2007-02-16
Genre: Science
ISBN: 3540300317

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This book differs from others on name reactions in organic chemistry by focusing on their mechanisms. It covers over 300 classical as well as contemporary name reactions. Biographical sketches for the chemists who discovered or developed those name reactions have been included. Each reaction is delineated by its detailed step-by-step, electron-pushing mechanism, supplemented with the original and the latest references, especially review articles. This book contains major improvements over the previous edition and the subject index is significantly expanded.


Comprehensive Organic Synthesis

Comprehensive Organic Synthesis
Author:
Publisher: Newnes
Total Pages: 9815
Release: 2014-02-14
Genre: Science
ISBN: 008097743X

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The second edition of Comprehensive Organic Synthesis—winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers—builds upon the highly respected first edition in drawing together the new common themes that underlie the many disparate areas of organic chemistry. These themes support effective and efficient synthetic strategies, thus providing a comprehensive overview of this important discipline. Fully revised and updated, this new set forms an essential reference work for all those seeking information on the solution of synthetic problems, whether they are experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis, Second Edition, Nine Volume Set an invaluable source, providing an authoritative overview of core concepts. Winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers Contains more than170 articles across nine volumes, including detailed analysis of core topics such as bonds, oxidation, and reduction Includes more than10,000 schemes and images Fully revised and updated; important growth areas—including combinatorial chemistry, new technological, industrial, and green chemistry developments—are covered extensively


The Chemistry of Indoles

The Chemistry of Indoles
Author: Richard Sundberg
Publisher: Elsevier
Total Pages: 505
Release: 2012-12-02
Genre: Science
ISBN: 0323147860

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Organic Chemistry, Volume 18: The Chemistry of Indoles discusses the chemistry of indole derivatives. This book explores the potent biological activity of several indole derivatives and explains the structure of indole alkaloids. Organized into 10 chapters, this monograph starts with an overview of the most important types of reactions of the indole ring on a mechanical basis. This text then proceeds to review the methods of synthesizing indoles and describes the oxidations and rearrangements of indole derivatives. Other chapters explore the special features of the synthesis and reactivity of hydroxyindoles, acylindoles, and aminoindoles. This book discusses as well the properties of carboxyl groups, which is substituted on the benzenoid ring of the indole nucleus that is typical of aromatic carboxylic acids. The final chapter deals with the certain classes of indoles that are found in nature. Chemists, researchers, and readers interested in the chemistry of indoles will find this book extremely useful.