The Dose Response Relation In Pharmacology PDF Download
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Author | : Ronald J. Tallarida |
Publisher | : Springer Science & Business Media |
Total Pages | : 218 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 1468462652 |
Download The Dose—Response Relation in Pharmacology Book in PDF, ePub and Kindle
This book is designed to meet the modern need for a better understanding of drug-receptor interaction as applied to the gathering and interpretation of dose-response data. It is an introduction suitable for any student who has had a first course in pharmacology. This book is an extension of the pharmacology course into one area of what is now known as molecular pharmacology. The material included is an outgrowth of courses that we have given in recent years to health-science students in several professional schools and universities. The area of drug-receptor theory, although just a part of molecular phar macology, is already very broad. One major line of investigation is concerned with the chemical and structural nature of specific receptors and with efforts to isolate specific receptors. Another line of investigation is concerned with the kinetic theories of drug-receptor interaction, the effort there being to provide a general theory that is applicable to wide classes of drugs. We have chosen to deal with the latter. There are several reasons for our choice of topics. First, the information is very practical; that is, it permits one to use properly and consistently terms such as "efficacy," "partial agonist," "pure antagonist," "potency," "pA2'" etc., when describing drug action. Second, many students fail to appreciate the differences in and the limitations of the various theories, beginning with the classical theory of A. J. Clark, on up to the very recent allosteric theories.
Author | : Adrian Kilcoyne |
Publisher | : OUP Oxford |
Total Pages | : 473 |
Release | : 2013-05-23 |
Genre | : Medical |
ISBN | : 0191510394 |
Download Pharmaceutical Medicine Book in PDF, ePub and Kindle
The breadth of the pharmaceutical medicine can be daunting, but this book is designed to navigate a path through the speciality. Providing a broad overview of all topics relevant to the discipline of pharmaceutical medicine, it gives you the facts fast, in a user-friendly format, without having to dive through page upon page of dense text. With 136 chapters spread across 8 sections, the text offers a thorough grounding in issues ranging from medicines regulation to clinical trial design and data management. This makes it a useful revision aid for exams as well as giving you a taster of areas of pharmaceutical medicine adjacent to your current role. For healthcare professionals already working in the field, this book offers a guiding hand in difficult situations as well as supplying rapid access to the latest recommendations and guidelines. Written by authors with experience in the industry and drug regulation, this comprehensive and authoritative guide provides a shoulder to lean on throughout your pharmaceutical career.
Author | : Ronald J Tallarida |
Publisher | : |
Total Pages | : 224 |
Release | : 1979-10-02 |
Genre | : |
ISBN | : 9781468462661 |
Download The Dose-Response Relation in Pharmacology Book in PDF, ePub and Kindle
Author | : Robert C. Bast, Jr. |
Publisher | : John Wiley & Sons |
Total Pages | : 2004 |
Release | : 2017-03-10 |
Genre | : Medical |
ISBN | : 111900084X |
Download Holland-Frei Cancer Medicine Book in PDF, ePub and Kindle
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Author | : Naitee Ting |
Publisher | : Springer Science & Business Media |
Total Pages | : 262 |
Release | : 2006-12-29 |
Genre | : Medical |
ISBN | : 0387337067 |
Download Dose Finding in Drug Development Book in PDF, ePub and Kindle
If you have ever wondered when visiting the pharmacy how the dosage of your prescription is determined this book will answer your questions. Dosing information on drug labels is based on discussion between the pharmaceutical manufacturer and the drug regulatory agency, and the label is a summary of results obtained from many scientific experiments. The book introduces the drug development process, the design and the analysis of clinical trials. Many of the discussions are based on applications of statistical methods in the design and analysis of dose response studies. Important procedural steps from a pharmaceutical industry perspective are also examined.
Author | : Matthew E. Cross |
Publisher | : Cambridge University Press |
Total Pages | : 439 |
Release | : 2014-03-06 |
Genre | : Medical |
ISBN | : 1107615887 |
Download Physics, Pharmacology and Physiology for Anaesthetists Book in PDF, ePub and Kindle
A quick reference to basic science for anaesthetists, containing all the key information needed for FRCA exams.
Author | : Philippa D. Darbre |
Publisher | : Academic Press |
Total Pages | : 390 |
Release | : 2015-03-21 |
Genre | : Medical |
ISBN | : 0128011203 |
Download Endocrine Disruption and Human Health Book in PDF, ePub and Kindle
Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human health Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations
Author | : Ronald Tallarida |
Publisher | : Springer |
Total Pages | : 0 |
Release | : 1984-07-30 |
Genre | : Medical |
ISBN | : 9780387905006 |
Download Manual of Pharmacologic Calculations Book in PDF, ePub and Kindle
This book provides a collection of quantitative procedures in common use in we selected may be pharmacology and related disciplines. The procedures considered" core" since it is likely that all scientists who work with drugs will use these procedures at some time or another. By excluding very specialized topics, we managed to keep the size of the book small. thus making it handy reference-a handbook in the true sense. for quick Since many scientists and students now have access to electronic computers, of lower cost microcomputers is likely to increase com and since the advent we also included a computer program for each puter availability even further, procedure. * The user need not know computer programming since all necessary information needed to run the programs is included here. The manual is divided into two parts. In the first, the pharmacologic basis for the calculation is briefly stated for each of the procedures (numbered 1 through 33). Then the appropriate equations (formulas) are given and an example of each calculation is provided. For each procedure, the discussion of theory and illustration of the calculation are brief and self-contained. With the tables in the Appendix and a pocket calculator, all of the calculations can be done without reference to any other source. It is recommended that the pro cedure and sample calculation be read and understood before going to the automated "magic" of the computer program in Part II.
Author | : Ronald J. Tallarida |
Publisher | : CRC Press |
Total Pages | : 268 |
Release | : 2000-07-21 |
Genre | : Mathematics |
ISBN | : 1420036106 |
Download Drug Synergism and Dose-Effect Data Analysis Book in PDF, ePub and Kindle
Not since this author's bestselling Manual of Pharmacologic Calculation has there been an available reference for drug data analysis. Incorporating the most relevant parts of that work, Drug Synergism and Dose-Effect Data Analysis focuses on drug combinations and all the quantitative analyses needed to analyze drug combination dose-effect data and to design experiments with two or more compounds. The book contains the statistical methods, the theory, and the computation algorithms needed to analyze single and combination drug data. Numerous examples accompany a presentation that illustrates the calculations and experimental design considerations for modern drug analysis.
Author | : Janet L. Stringer |
Publisher | : McGraw Hill Professional |
Total Pages | : 254 |
Release | : 2011-03-11 |
Genre | : Medical |
ISBN | : 0071769420 |
Download Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, Fourth Edition Book in PDF, ePub and Kindle
A time-saving, stress-reducing approach to learning the essential concepts of pharmacology Great for USMLE review! "This could be a very useful tool for students who struggle with understanding the most basic concepts in pharmacology for course and licensure examinations. 3 Stars."--Doody's Review Service Basic Concepts in Pharmacology provides you with a complete framework for studying -– and understanding -- the fundamental principles of drug actions. With this unique learning system, you’ll be able to identify must-know material, recognize your strengths and weaknesses, minimize memorization, streamline your study, and build your confidence. Basic Concepts in Pharmacology presents drugs by class, details exactly what you need to know about each class, and reinforces key concepts and definitions. With this innovative text you’ll be able to: Recognize the concepts you truly must know before moving on to other material Understand the fundamental principles of drug actions Organize and condense the drug information you must remember Review key information, which is presented in boxes, illustrations, and tables Identify the most important drugs in each drug class Seven sections specifically designed to simplify the learning process and help you gain an understanding of the most important concepts: General Principles Drugs That Affect the Autonomic Nervous System Drugs That Affect the Cardiovascular System Drugs That Act on the Central Nervous System Chemotherapeutic Agents Drugs That Affect the Endocrine System Miscellaneous Drugs (Includes Toxicology and Poisoning)