Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download The Dissolution Kinetics Of Some Sulphonylureas And Solid Dispersions PDF full book. Access full book title The Dissolution Kinetics Of Some Sulphonylureas And Solid Dispersions.
| Author | : Peter Veng Pedersen |
| Publisher | : |
| Total Pages | : 260 |
| Release | : 1974 |
| Genre | : Biopharmaceutics |
| ISBN | : |
| Author | : Navnit Shah |
| Publisher | : Springer |
| Total Pages | : 702 |
| Release | : 2014-11-21 |
| Genre | : Medical |
| ISBN | : 1493915983 |
This volume offers a comprehensive guide on the theory and practice of amorphous solid dispersions (ASD) for handling challenges associated with poorly soluble drugs. In twenty-three inclusive chapters, the book examines thermodynamics and kinetics of the amorphous state and amorphous solid dispersions, ASD technologies, excipients for stabilizing amorphous solid dispersions such as polymers, and ASD manufacturing technologies, including spray drying, hot melt extrusion, fluid bed layering and solvent-controlled micro-precipitation technology (MBP). Each technology is illustrated by specific case studies. In addition, dedicated sections cover analytical tools and technologies for characterization of amorphous solid dispersions, the prediction of long-term stability, and the development of suitable dissolution methods and regulatory aspects. The book also highlights future technologies on the horizon, such as supercritical fluid processing, mesoporous silica, KinetiSol®, and the use of non-salt-forming organic acids and amino acids for the stabilization of amorphous systems. Amorphous Solid Dispersions: Theory and Practice is a valuable reference to pharmaceutical scientists interested in developing bioavailable and therapeutically effective formulations of poorly soluble molecules in order to advance these technologies and develop better medicines for the future.
| Author | : Edward Tiekink |
| Publisher | : Walter de Gruyter GmbH & Co KG |
| Total Pages | : 364 |
| Release | : 2017-11-20 |
| Genre | : Science |
| ISBN | : 3110464950 |
In this volume, contributions covering the theoretical and practical aspects of multicomponent crystals provide a timely and contemporary overview of the state-of-the art of this vital aspect of crystal engineering/materials science. With a solid foundation in fundamentals, multi-component crystals can be formed, for example, to enhance pharmaceutical properties of drugs, for the specific control of optical responses to external stimuli and to assemble molecules to allow chemical reactions that are generally intractable following conventional methods. Contents Pharmaceutical co-crystals: crystal engineering and applications Pharmaceutical multi-component crystals: improving the efficacy of anti-tuberculous agents Qualitative and quantitative crystal engineering of multi-functional co-crystals Control of photochromism in N-salicylideneaniline by crystal engineering Quinoline derivatives for multi-component crystals: principles and applications N-oxides in multi-component crystals and in bottom-up synthesis and applications Multi-component crystals and non-ambient conditions Co-crystals for solid-state reactivity and thermal expansion Solution co-crystallisation and its applications The salt-co-crystal continuum in halogen-bonded systems Large horizontal displacements of benzene-benzene stacking interactions in co-crystals Simultaneous halogen and hydrogen bonding to carbonyl and thiocarbonylfunctionality Crystal chemistry of the isomeric N,N’-bis(pyridin-n-ylmethyl)-ethanediamides, n = 2, 3 or 4 Solute・solvent interactions mediated by main group element (lone-pair)・・・π(aryl) interactions
| Author | : James E. Barrett |
| Publisher | : Springer Nature |
| Total Pages | : 466 |
| Release | : 2019-12-24 |
| Genre | : Medical |
| ISBN | : 3030353621 |
Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.
| Author | : Jochen Kuhlmann |
| Publisher | : Springer |
| Total Pages | : 778 |
| Release | : 1996 |
| Genre | : Health & Fitness |
| ISBN | : |
Diabetes continues to spread worldwide. Traditionally diabetes in adults has not been considered a serious life-threatening disease. This attitude needs to be changed, however, since the complications associated with the adult form of diabetes affect almost every organ system. The high morbidity and mortality of Non-Insulin-Dependent Diabetes Mellitus (NIDDM) suggest that current treatment strategies are unsatisfactory, pointing to an urgent need for new therapeutic approaches. This volume provides a comprehensive description and evaluation of recently obtained and previously unpublished data written by leading experts in the field, together with a discussion of antidiabetics under development and new approaches for the management of type 2 diabetes.
| Author | : Rebecca White |
| Publisher | : Pharmaceutical Press |
| Total Pages | : 753 |
| Release | : 2015-03-11 |
| Genre | : Medical |
| ISBN | : 0857111620 |
With over 400 drug monographs, this book covers the technical, practical and legal aspects that you should consider before prescribing or administering drugs via enteral feeding tubes.
| Author | : Joseph I. Boullata |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 823 |
| Release | : 2010-03-17 |
| Genre | : Science |
| ISBN | : 160327362X |
Handbook of Drug-Nutrient Interactions, Second Edition is an essential new work that provides a scientific look behind many drug-nutrient interactions, examines their relevance, offers recommendations, and suggests research questions to be explored. In the five years since publication of the first edition of the Handbook of Drug-Nutrient Interactions new perspectives have emerged and new data have been generated on the subject matter. Providing both the scientific basis and clinical relevance with appropriate recommendations for many interactions, the topic of drug-nutrient interactions is significant for clinicians and researchers alike. For clinicians in particular, the book offers a guide for understanding, identifying or predicting, and ultimately preventing or managing drug-nutrient interactions to optimize patient care. Divided into six sections all chapters have been revised or are new to this edition. Chapters balance the most technical information with practical discussions and include outlines that reflect the content; discussion questions that can guide the reader to the critical areas covered in each chapter, complete definitions of terms with the abbreviation fully defined and consistent use of terms between chapters. The editors have performed an outstanding service to clinical pharmacology and pharmaco-nutrition by bringing together a multi-disciplinary group of authors. Handbook of Drug-Nutrient Interactions, Second Edition is a comprehensive up-to-date text for the total management of patients on drug and/or nutrition therapy but also an insight into the recent developments in drug-nutrition interactions which will act as a reliable reference for clinicians and students for many years to come.
| Author | : Sujoy Ghosh |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 343 |
| Release | : 2012-07-16 |
| Genre | : Medical |
| ISBN | : 1455742112 |
The incidence of diabetes is increasing at epidemic proportions worldwide, presenting a huge challenge to modern medicine. In response, scientific advances in the understanding of diabetes and its complications are being translated into improved clinical practice at ever faster rates. Greater understanding of aetiopathogenesis of the different types of diabetes, the emerging roles of novel pharmacological agents and the importance placed on multidisciplinary team working and multi-risk-factor treatment all contribute to this. Now in a fully revised second edition, this clear, concise guide to modern diabetes and its management will prove invaluable to all health professionals in this field. Suitable for instant reference in the clinic or office. Helps answer the questions which diabetic patients will direct at their carers about their disease, its causes, prognosis and consequences for their lifestyle. Offers practical and accessible advice on all aspects of the condition from presentation and diagnosis to organisation of care. Suitable for diabetic nurses as well as junior doctors. Evidence based boxes give the rationale behind treatment decisions. Colour illustrations of important conditions such as diabetic retinopathy and foot disease. Key points highlighted throughout the book, vital/high risk points emphasized with exclamation mark icon. More information on insulin therapy, dyslipidaemia, macrovascular disease and hypertension. Complete rewrite of oral antidiabetic agents section. Smaller, more pocketable page size.
| Author | : Leonardo F. Fraceto |
| Publisher | : Springer Nature |
| Total Pages | : 373 |
| Release | : 2020-07-06 |
| Genre | : Technology & Engineering |
| ISBN | : 3030448738 |
This book explores the development of nanopesticides and tests of their biological activity against target organisms. It also covers the effects of nanopesticides in the aquatic and terrestrial environments, along with related subjects including fate, behaviour, mechanisms of action and toxicity. Moreover, the book discusses the potential risks of nanopesticides for non-target organisms, as well as regulatory issues and future perspectives.
| Author | : Sarfaraz K. Niazi |
| Publisher | : CRC Press |
| Total Pages | : 602 |
| Release | : 2007-08-22 |
| Genre | : Medical |
| ISBN | : 0849383595 |
As the generic pharmaceutical industry continues to grow and thrive, so does the need to conduct efficient and successful bioequivalence studies. In recent years, there have been significant changes to the statistical models for evaluating bioequivalence, and advances in the analytical technology used to detect drug and metabolite levels have made
