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The Development of an In-vivo Dosimeter for the Application in Radiotherapy

The Development of an In-vivo Dosimeter for the Application in Radiotherapy
Author: Rajiv Bose
Publisher:
Total Pages:
Release: 2012
Genre:
ISBN:

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The expectation for continual improvements in the treatment of cancer has brought quality assurance in radiotherapy under scrutiny in recent years. After a cancer diagnosis a custom treatment plan is devised to meet the particular needs of the patient's condition based on their prognosis. A cancer treatment plan will typically comprise of several cancer treatment technologies combining to form a comprehensive programme to fight the malignant growth. Inherent in each cancer treatment technology is a percentage error in treatment accuracy. Quality assurance is the medical practice to minimise the percentage error in treatment accuracy. Radiotherapy is one of the several cancer treatment technologies a patient might receive as part of their treatment plan, and in-vivo dosimetry is a quality assurance technology specifically designed to minimise the percentage error in the treatment accuracy of radiotherapy. This thesis outlines the work completed in the design of a next generation dosimeter for in-vivo dosimetry. The proposed dosimeter is intended to modernise the process of measuring the absorbed dose of ionising radiation received by the target volume during a radiotherapy session. To accomplish this goal the new dosimeter will amalgamate specialist technologies from the field of particle physics and reapply them to the field of medical physics. This thesis describes the design of a new implantable in-vivo dosimeter, a dosimeter comprising of several individual stages of electronics working together to modernise quality assurance in radiotherapy. Presented within this thesis are the results demonstrating the performance of two critical stages for this new dosimeter, including: the oating gate metal oxide field effective transistor, a radiation sensitive electronic component measuring an absorbed dose of radiation; and the micro antenna, a highly specialist wireless communications device working to transmit a high frequency radio signal. This was a collaborative project between Rutherford Appleton Laboratory and Brunel University. The presented work in this thesis was completed between March 2007 and January 2011.


Development of Procedures for in Vivo Dosimetry in Radiotherapy

Development of Procedures for in Vivo Dosimetry in Radiotherapy
Author: International Atomic Energy Agency
Publisher:
Total Pages: 0
Release: 2013
Genre: Science
ISBN: 9789201416100

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Provides a comprehensive overview of the development of procedures for in vivo dosimetry in radiotherapy. It elaborates on the technology behind in vivo dosimetry and describes an initial set of measurements.


Radiation Therapy Dosimetry

Radiation Therapy Dosimetry
Author: Arash Darafsheh
Publisher: CRC Press
Total Pages: 505
Release: 2021-03-08
Genre: Medical
ISBN: 1351005375

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This comprehensive book covers the everyday use and underlying principles of radiation dosimeters used in radiation oncology clinics. It provides an up-to-date reference spanning the full range of current modalities with emphasis on practical know-how. The main audience is medical physicists, radiation oncology physics residents, and medical physics graduate students. The reader gains the necessary tools for determining which detector is best for a given application. Dosimetry of cutting edge techniques from radiosurgery to MRI-guided systems to small fields and proton therapy are all addressed. Main topics include fundamentals of radiation dosimeters, brachytherapy and external beam radiation therapy dosimetry, and dosimetry of imaging modalities. Comprised of 30 chapters authored by leading experts in the medical physics community, the book: Covers the basic principles and practical use of radiation dosimeters in radiation oncology clinics across the full range of current modalities. Focuses on providing practical guidance for those using these detectors in the clinic. Explains which detector is more suitable for a particular application. Discusses the state of the art in radiotherapy approaches, from radiosurgery and MR-guided systems to advanced range verification techniques in proton therapy. Gives critical comparisons of dosimeters for photon, electron, and proton therapies.


In Vivo Dosimetry in Radiotherapy and Radiology

In Vivo Dosimetry in Radiotherapy and Radiology
Author: Abdelmoneim Sulieman
Publisher: LAP Lambert Academic Publishing
Total Pages: 156
Release: 2011-07
Genre: Radiation dosimetry
ISBN: 9783845406862

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Radiation dosimetry was originally developed as a tool to quantify biological effects for use in setting dose limits for radiation protection and to determine accurately the irradiation needed to treat tumors or to prevent from deterministic effects and radiation risks. In this book Thermoluminescence Dosimeters (TLD) used in diagnostic, interventional radiology and radiotherapy were studied in terms of dose measurement, optimisation and radiation risk reduction for patients and staff.This book is intended to describe the measurement radiation dose for both patients and staff during diagnostic and radiation therapy using TLDs. It also describes methods of radiation dose optimization during diagnostic and interventional radiology by measuring the entrance and pripheral doses to thyroid and skin for patients during breast, head and neck and prostate treatments. The use of build up caps constructed from materials with different atomic number enable us to measure high radiation energies with acceptable accuracy. The radiation risk for both patients and staff was also evaluated. Therefore, this book provide new data and ideas for clinical medical physicists and dosimetrists.


Scintillation Dosimetry

Scintillation Dosimetry
Author: Sam Beddar
Publisher: CRC Press
Total Pages: 424
Release: 2016-04-06
Genre: Medical
ISBN: 1482209004

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Scintillation Dosimetry delivers a comprehensive introduction to plastic scintillation dosimetry, covering everything from basic radiation dosimetry concepts to plastic scintillating fiber optics. Comprised of chapters authored by leading experts in the medical physics community, the book: Discusses a broad range of technical implementations, from point source dosimetry scaling to 3D-volumetric and 4D-scintillation dosimetry Addresses a wide scope of clinical applications, from machine quality assurance to small-field and in vivo dosimetry Examines related optical techniques, such as optically stimulated luminescence (OSL) or Čerenkov luminescence Thus, Scintillation Dosimetry provides an authoritative reference for detailed, state-of-the-art information on plastic scintillation dosimetry and its use in the field of radiation dosimetry.


Optically Stimulated Luminescence Dosimetry

Optically Stimulated Luminescence Dosimetry
Author: L. Boetter-Jensen
Publisher: Elsevier
Total Pages: 375
Release: 2003-10-24
Genre: Science
ISBN: 008053807X

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Optically Stimulated Luminescence (OSL) has become the technique of choice for many areas of radiation dosimetry. The technique is finding widespread application in a variety of radiation dosimetry fields, including personal monitoring, environmental monitoring, retrospective dosimetry (including geological dating and accident dosimetry), space dosimetry, and many more. In this book we have attempted to synthesize the major advances in the field, covering both fundamental understanding and the many applications. The latter serve to demonstrate the success and popularity of OSL as a dosimetry method. The book is designed for researchers and radiation dosimetry practitioners alike. It delves into the detailed theory of the process from the point of view of stimulated relaxation phenomena, describing the energy storage and release processes phenomenologically and developing detailed mathematical descriptions to enable a quantitative understanding of the observed phenomena. The various stimulation modes (continuous wave, pulsed, or linear modulation) are introduced and compared. The properties of the most important synthetic OSL materials beginning with the dominant carbon-doped Al2O3, and moving through discussions of other, less-well studied but nevertheless important, or potentially important, materials. The OSL properties of the two most important natural OSL dosimetry material types, namely quartz and feldspars are discussed in depth. The applications chapters deal with the use of OSL in personal, environmental, medical and UV dosimetry, geological dating and retrospective dosimetry (accident dosimetry and dating). Finally the developments in instrumentation that have occurred over the past decade or more are described. The book will find use in those laboratories within academia, national institutes and the private sector where research and applications in radiation dosimetry using luminescence are being conducted. Potential readers include personnel involved in radiation protection practice and research, hospitals, nuclear power stations, radiation clean-up and remediation, food irradiation and materials processing, security monitoring, geological and archaeological dating, luminescence studies of minerals, etc.


Recent Advancements and Applications in Dosimetry

Recent Advancements and Applications in Dosimetry
Author: Maria F. Chan
Publisher:
Total Pages: 0
Release: 2018
Genre: Radiation dosimetry
ISBN: 9781536137590

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Features: Provides unique dosimetry for high intensity MR-guided ultrasound treatment, gold nanoparticle-enhanced radiotherapy, photodynamic therapy, thermal imaging in Bbrachytherapy, MR-guided radiotherapy, proton beam treatment, and high-definition end-to-end patient-specific dose verification. Offers clinical applications for all varieties of modern radiation detectors, and evolving dosimetry techniques including innovative calorimetry, TLD, Oone-scan film dosimetry, transmission detectors, real-time EPID dosimetry, best feasible DVH planning, 3D printing, 5D planning and delivery, as well as machine learning Summary This book provides a comprehensive collection of the newly emerging treatment modalities, covering high intensity ultrasound treatment, photodynamic therapy, MR-guided treatment machines, nanoparticle-enhanced radiotherapy, and proton beam therapy. The invited expert authors cover a wide range of the latest advancements and developments in dosimetry techniques as well asnd their clinical implications, including calorimetry, radiochromic film, transmission detectors, real-time portal dosimetry, TLD, thermal imaging dosimetry, 3D dosimetry, best feasible DVH planning, 5D planning and delivery, 3D printing, as well as machine learning in medical dosimetry. This book will bring the reader up-to-date with the state of the art in radiation dosimetry and best clinical practices using such advanced detectors.


Clinical 3D Dosimetry in Modern Radiation Therapy

Clinical 3D Dosimetry in Modern Radiation Therapy
Author: Ben Mijnheer
Publisher: CRC Press
Total Pages: 845
Release: 2017-10-31
Genre: Science
ISBN: 1351645110

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This book provides a first comprehensive summary of the basic principles, instrumentation, methods, and clinical applications of three-dimensional dosimetry in modern radiation therapy treatment. The presentation reflects the major growth in the field as a result of the widespread use of more sophisticated radiotherapy approaches such as intensity-modulated radiation therapy and proton therapy, which require new 3D dosimetric techniques to determine very accurately the dose distribution. It is intended as an essential guide for those involved in the design and implementation of new treatment technology and its application in advanced radiation therapy, and will enable these readers to select the most suitable equipment and methods for their application. Chapters include numerical data, examples, and case studies.