The Design And Development Of Novel Drugs And Vaccines PDF Download
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| Author | : Tarun Kumar Bhatt |
| Publisher | : Academic Press |
| Total Pages | : 310 |
| Release | : 2021-01-21 |
| Genre | : Business & Economics |
| ISBN | : 0128214759 |
Download The Design and Development of Novel Drugs and Vaccines Book in PDF, ePub and Kindle
The Design and Development of Novel Drugs and Vaccines: Principles and Protocols presents both in silico methods and experimental protocols for vaccine and drug design and development, critically reviewing the most current research and emphasizing approaches and technologies that accelerate and lower the cost of product development. Sections review the technologies and approaches used to identify, characterize and establish a protein as a new drug and vaccine target, cover several molecular methods for in vitro studies of the desired target, and present various physiological parameters for in vivo studies. The book includes preclinical trials and research, along with information on FDA approval. Covers both in silico methods and experimental protocols for vaccine and drug development in a single, accessible volume Offers a holistic accounting of how developments in bioinformatics and large experimental datasets can be used in the development of vaccines and drugs Shows researchers the entire gamut of current therapies, ranging from computational inputs to animal studies Reviews the most current, cutting-edge research available on vaccine and drug design and development
| Author | : Kishore R. Sakharkar |
| Publisher | : CRC Press |
| Total Pages | : 451 |
| Release | : 2022-09-01 |
| Genre | : Science |
| ISBN | : 1000795713 |
Download Post-genomic Approaches in Drug and Vaccine Development Book in PDF, ePub and Kindle
Over the past decade, genome sequencing projects and the associated efforts have facilitated the discovery of several novel disease targets and the approval of several innovative drugs. To further exploit this data for human health and disease, there is a need to understand the genome data itself in detail, discover novel targets, understand their role in physiological pathways and associated diseases, with the aim to translate these discoveries to clinical and preventive medicine. It is equally important to understand the labors and limitations in integrating clinical phenotypes with genomic, transcriptomic, proteomic and metabolomic approaches. T
| Author | : Lisa M.. Plitnick |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2015 |
| Genre | : |
| ISBN | : |
Download Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics Book in PDF, ePub and Kindle
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 442 |
| Release | : 2011-04-03 |
| Genre | : Medical |
| ISBN | : 0309158060 |
Download Rare Diseases and Orphan Products Book in PDF, ePub and Kindle
Rare diseases collectively affect millions of Americans of all ages, but developing drugs and medical devices to prevent, diagnose, and treat these conditions is challenging. The Institute of Medicine (IOM) recommends implementing an integrated national strategy to promote rare diseases research and product development.
| Author | : Rino Rappuoli |
| Publisher | : Caister Academic Press Limited |
| Total Pages | : 0 |
| Release | : 2011 |
| Genre | : Medical |
| ISBN | : 9781904455745 |
Download Vaccine Design Book in PDF, ePub and Kindle
In this book, expert international authors critically review the current cutting-edge research in vaccine design and development. Particular emphasis is given to new approaches and technologies.
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 103 |
| Release | : 2020-01-27 |
| Genre | : Medical |
| ISBN | : 0309498511 |
Download The Role of NIH in Drug Development Innovation and Its Impact on Patient Access Book in PDF, ePub and Kindle
To explore the role of the National Institutes of Health (NIH) in innovative drug development and its impact on patient access, the Board on Health Care Services and the Board on Health Sciences Policy of the National Academies jointly hosted a public workshop on July 24â€"25, 2019, in Washington, DC. Workshop speakers and participants discussed the ways in which federal investments in biomedical research are translated into innovative therapies and considered approaches to ensure that the public has affordable access to the resulting new drugs. This publication summarizes the presentations and discussions from the workshop.
| Author | : Susanna Wu-Pong |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 374 |
| Release | : 2010-01-11 |
| Genre | : Medical |
| ISBN | : 1597455326 |
Download Biopharmaceutical Drug Design and Development Book in PDF, ePub and Kindle
This book provides a comprehensive examination of the newest biopharmaceutical drugs. Among the drugs discussed are ones in the categories of monoclonal antibodies for in-vivo use, cytokines, growth factors, enzymes, immunomodulators, thrombolytics, and immonotherapies including vaccines. Additionally, the volume examines new and emerging technologies, and contains a review of the Human Genome Project.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 472 |
| Release | : 2001-02-21 |
| Genre | : Medical |
| ISBN | : 0309174988 |
Download Vaccines for the 21st Century Book in PDF, ePub and Kindle
Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis. What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development. This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines: Lessons to be learned from the polio experience. Scientific advances that set the stage for new vaccines. Factors that affect how vaccines are used in the population. Value judgments and ethical questions raised by comparison of health needs and benefits. The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.
| Author | : Manju Rawat Singh |
| Publisher | : Academic Press |
| Total Pages | : 657 |
| Release | : 2020-04-07 |
| Genre | : Business & Economics |
| ISBN | : 0128199180 |
Download Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents Book in PDF, ePub and Kindle
Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents provides sound data on the utility of biological and plant-based drugs and describes challenges faced in all aspects offering indispensable strategies to use in the development of bioactive medicines. Bioactive based medications are commonly used throughout the world and have been recognized by physicians and patients for their therapeutic efficacy. Bioactive formulations, including their subordinates and analogs, address 50% of all medicines in clinical practice. Novel bioactive medicine transporters can cure many disorders by both spatial and transitory approaches and have various justifications in medicinal potential. This book presents information on the utility of natural, plant, animal and bioengineered bioactive materials. It is a fundamental source of information and data for pharmacognosists, pharmaceutical analysts, drug transport scientists and pharmacologists working in bioactive medications. Advances information on various bioactive based medications, their sources, clinical consequences and transport strategies Illustrates diverse transport systems for bioactives and derivatives, novel techniques for formulations, targeting strategies and fundamental qualities of developed bioactive carriers, and their safety concerns and standardization Discusses distinctive transport systems, stability, upgraded dissolvability, and enhanced bioavailability of bioactives
| Author | : Darren R. Flower |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 316 |
| Release | : 2012-12-09 |
| Genre | : Medical |
| ISBN | : 1461450705 |
Download Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines Book in PDF, ePub and Kindle
This volume will address an important emergent area within the field of immunomics: the discovery of antigens and adjuvants within the context of reverse vaccinology. Conventional approaches to vaccine design and development requires pathogens to be cultivated in the laboratory and the immunogenic molecules within them to be identifiable. Conventional vaccinology is no longer universally successful, particularly for recalcitrant pathogens. By using genomic information we can study vaccine development in silico: 'reverse vaccinology', can identify candidate subunits vaccines by identifying antigenic proteins and by using equally rational approaches to identify novel immune response-enhancing adjuvants.
