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The Computational Mechanics of Bone Tissue

The Computational Mechanics of Bone Tissue
Author: Jorge Belinha
Publisher: Springer Nature
Total Pages: 249
Release: 2020-02-11
Genre: Science
ISBN: 3030375412

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This book offers a timely snapshot of computational methods applied to the study of bone tissue. The bone, a living tissue undergoing constant changes, responds to chemical and mechanical stimuli in order to maximize its mechanical performance. Merging perspectives from the biomedical and the engineering science fields, the book offers some insights into the overall behavior of this complex biological tissue. It covers three main areas: biological characterization of bone tissue, bone remodeling algorithms, and numerical simulation of bone tissue and adjacent structures. Written by clinicians and researchers, and including both review chapters and original research, the book offers an overview of the state-of-the-art in computational mechanics of bone tissue, as well as a good balance of biological and engineering methods for bone tissue analysis. An up-to-date resource for mechanical and biomedical engineers seeking new ideas, it also promotes interdisciplinary collaborations to advance research in the field.


The Computational Mechanics of Bone Tissue

The Computational Mechanics of Bone Tissue
Author:
Publisher:
Total Pages: 249
Release: 2020
Genre: Bones
ISBN: 9783030375423

Download The Computational Mechanics of Bone Tissue Book in PDF, ePub and Kindle

This book offers a timely snapshot of computational methods applied to the study of bone tissue. The bone, a living tissue undergoing constant changes, responds to chemical and mechanical stimuli in order to maximize its mechanical performance. Merging perspectives from the biomedical and the engineering science fields, the book offers some insights into the overall behavior of this complex biological tissue. It covers three main areas: biological characterization of bone tissue, bone remodeling algorithms, and numerical simulation of bone tissue and adjacent structures. Written by clinicians and researchers, and including both review chapters and original research, the book offers an overview of the state-of-the-art in computational mechanics of bone tissue, as well as a good balance of biological and engineering methods for bone tissue analysis. An up-to-date resource for mechanical and biomedical engineers seeking new ideas, it also promotes interdisciplinary collaborations to advance research in the field. --


Computational Modeling in Tissue Engineering

Computational Modeling in Tissue Engineering
Author: Liesbet Geris
Publisher: Springer Science & Business Media
Total Pages: 438
Release: 2012-10-30
Genre: Technology & Engineering
ISBN: 3642325637

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One of the major challenges in tissue engineering is the translation of biological knowledge on complex cell and tissue behavior into a predictive and robust engineering process. Mastering this complexity is an essential step towards clinical applications of tissue engineering. This volume discusses computational modeling tools that allow studying the biological complexity in a more quantitative way. More specifically, computational tools can help in: (i) quantifying and optimizing the tissue engineering product, e.g. by adapting scaffold design to optimize micro-environmental signals or by adapting selection criteria to improve homogeneity of the selected cell population; (ii) quantifying and optimizing the tissue engineering process, e.g. by adapting bioreactor design to improve quality and quantity of the final product; and (iii) assessing the influence of the in vivo environment on the behavior of the tissue engineering product, e.g. by investigating vascular ingrowth. The book presents examples of each of the above mentioned areas of computational modeling. The underlying tissue engineering applications will vary from blood vessels over trachea to cartilage and bone. For the chapters describing examples of the first two areas, the main focus is on (the optimization of) mechanical signals, mass transport and fluid flow encountered by the cells in scaffolds and bioreactors as well as on the optimization of the cell population itself. In the chapters describing modeling contributions in the third area, the focus will shift towards the biology, the complex interactions between biology and the micro-environmental signals and the ways in which modeling might be able to assist in investigating and mastering this complexity. The chapters cover issues related to (multiscale/multiphysics) model building, training and validation, but also discuss recent advances in scientific computing techniques that are needed to implement these models as well as new tools that can be used to experimentally validate the computational results.


Finite Element Analysis of Bone Remodeling - Implementation of a Remodeling Algorithm in MATLAB and ANSYS

Finite Element Analysis of Bone Remodeling - Implementation of a Remodeling Algorithm in MATLAB and ANSYS
Author: Martin Groß
Publisher: GRIN Verlag
Total Pages: 118
Release: 2008-08
Genre: Bone remodeling
ISBN: 3640140052

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Master's Thesis from the year 2006 in the subject Medicine - Biomedical Engineering, grade: 1.0, Technical University of Munich (LS Statik), course: Master of Science of Computational Mechanics, 94 entries in the bibliography, language: English, abstract: The process of adaptive bone remodeling can be described mathematically and simulated in a computer model, integrated with the finite element method. The main focus of this thesis is the implementation of a bone remodeling algorithm in MATLAB and ANSYS on the basis of FEM. The strain energy density is used as mechanical stimulus. The cortical and trabecular bone are described as continuous materials with variable density. This thesis can be divided into four main parts. The first part is due to the material properties of cortical and trabecular bone. The second part is about the remodeling theory and gives an historical review of the developed numerical approaches up to now. The implementation of the remodeling algorithm in ANSYS and MATLAB as well as its validation is topic of part three. In last main part, the algorithm is applied to a 2D FE-model of a human proximal femur.


Meshless Methods in Biomechanics

Meshless Methods in Biomechanics
Author: Jorge Belinha
Publisher: Springer
Total Pages: 328
Release: 2014-05-14
Genre: Technology & Engineering
ISBN: 3319064002

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This book presents the complete formulation of a new advanced discretization meshless technique: the Natural Neighbour Radial Point Interpolation Method (NNRPIM). In addition, two of the most popular meshless methods, the EFGM and the RPIM, are fully presented. Being a truly meshless method, the major advantages of the NNRPIM over the FEM and other meshless methods, are the remeshing flexibility and the higher accuracy of the obtained variable field. Using the natural neighbour concept, the NNRPIM permits to determine organically the influence-domain, resembling the cellulae natural behaviour. This innovation permits the analysis of convex boundaries and extremely irregular meshes, which is an advantage in the biomechanical analysis, with no extra computational effort associated. This volume shows how to extend the NNRPIM to the bone tissue remodelling analysis, expecting to contribute with new numerical tools and strategies in order to permit a more efficient numerical biomechanical analysis.


Bone Remodeling Process

Bone Remodeling Process
Author: Rabeb Ben Kahla
Publisher: Academic Press
Total Pages: 238
Release: 2021-08-14
Genre: Technology & Engineering
ISBN: 0323902057

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Bone Remodeling Process: Mechanics, Biology, and Numerical Modeling provides a literature review. The first part of the book discusses bones in a normal physiological condition, bringing together the involved actors and factors reported over the past two decades, and the second discusses pathological conditions, highlighting the attack vectors of each bone disease. The third part is devoted to the mathematical descriptions of bone remodeling, formulated to develop models able to provide information that is not amenable to direct measurement, while the last part focuses on models using the finite element method in investigating bone biomechanics.This book creates an overall image of the complex communication network established between the diverse remodeling actors, based on overwhelming control evidence revealed over recent years, as well as visualizes the remodeling defects and possible treatments in each case. It also regroups the models allowing readers to analyze and assess bone mechanical and biological properties. This book details the cellular mechanisms allowing the bone to adapt its microarchitecture to the requirements of the human body, which is the main issue in bone biology and presents the evolution of mathematical modeling used in a bone computer simulation. Each chapter covers a core topic in bone biomechanics Provides a multidisciplinary view that effectively links orthopaedics, cellular biology, mechanics, and computer simulation Draws an overall image about bone biology and cell interactions, for identifying cell populations that are crucial for the remodeling process


Biomedical Imaging and Computational Modeling in Biomechanics

Biomedical Imaging and Computational Modeling in Biomechanics
Author: Ugo Andreaus
Publisher: Springer Science & Business Media
Total Pages: 208
Release: 2012-10-09
Genre: Technology & Engineering
ISBN: 940074269X

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This book collects the state-of-art and new trends in image analysis and biomechanics. It covers a wide field of scientific and cultural topics, ranging from remodeling of bone tissue under the mechanical stimulus up to optimizing the performance of sports equipment, through the patient-specific modeling in orthopedics, microtomography and its application in oral and implant research, computational modeling in the field of hip prostheses, image based model development and analysis of the human knee joint, kinematics of the hip joint, micro-scale analysis of compositional and mechanical properties of dentin, automated techniques for cervical cell image analysis, and biomedical imaging and computational modeling in cardiovascular disease. The book will be of interest to researchers, Ph.D students, and graduate students with multidisciplinary interests related to image analysis and understanding, medical imaging, biomechanics, simulation and modeling, experimental analysis


Computational Biomechanics for Medicine

Computational Biomechanics for Medicine
Author: Grand R. Joldes
Publisher: Springer
Total Pages: 212
Release: 2016-06-15
Genre: Technology & Engineering
ISBN: 3319283294

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The Computational Biomechanics for Medicine titles provide an opportunity for specialists in computational biomechanics to present their latest methodologies and advancements. This volume comprises eighteen of the newest approaches and applications of computational biomechanics, from researchers in Australia, New Zealand, USA, UK, Switzerland, Scotland, France and Russia. Some of the interesting topics discussed are: tailored computational models; traumatic brain injury; soft-tissue mechanics; medical image analysis; and clinically-relevant simulations. One of the greatest challenges facing the computational engineering community is to extend the success of computational mechanics to fields outside traditional engineering, in particular to biology, the biomedical sciences, and medicine. We hope the research presented within this book series will contribute to overcoming this grand challenge.


Technological Adoption and Trends in Health Sciences Teaching, Learning, and Practice

Technological Adoption and Trends in Health Sciences Teaching, Learning, and Practice
Author: Marcos-Pablos, Samuel
Publisher: IGI Global
Total Pages: 387
Release: 2022-02-11
Genre: Medical
ISBN: 179988872X

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The use of technology in health sciences has a direct impact on health outcomes, as well as on the quality and the safety of healthcare processes. In addition, the use of new technological developments in medical education has proven to be greatly effective and creates realistic learning environments to experience procedures and devices that will become common in medical practice. However, bringing new technologies into the health sector is a complex task, which is why a comprehensive vision of the health sciences ecosystem (encompassing many different areas of research) is vital. Technological Adoption and Trends in Health Sciences Teaching, Learning, and Practice obtains an overview of the technological trends within the health sciences ecosystem, identifies the strengths and weaknesses of the research presented to date, and depicts possible future research directions within health science education and practice. Covering topics such as artificial intelligence and online laboratories, it is ideal for health sciences educators and practitioners, technological solution providers, health organizations, health and care workers, regulators, governing bodies, researchers, academicians, and students.


Mechanics of Biological Tissue

Mechanics of Biological Tissue
Author: Gerhard A. Holzapfel
Publisher: Springer Science & Business Media
Total Pages: 510
Release: 2006-06-03
Genre: Science
ISBN: 354031184X

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The mechanics of biological tissues is a multidisciplinary and rapidly expanding area of research. This book points to important directions combining mechanical sciences with the new developments in biology. It delivers articles on mechanics of tissues at the molecular, cellular, tissue and organ levels.