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The Biology of Taurine

The Biology of Taurine
Author: Ryan J. Huxtable
Publisher: Springer Science & Business Media
Total Pages: 397
Release: 2013-11-11
Genre: Medical
ISBN: 1489904050

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I was pleased and at the same time filled with some misgivings when Professors Alberto Giotti end Ryan Huxtable asked me to introduce this book. The book is the outcome of the Symposium held in Firenze-San Miniato (PI), October 6-9, 1986. The symposium was entitled "Sulfur Amino Acids, Peptides and Related Compounds" and was the 7th international symposium on taurine ßnd assooiated substances. It is always difficult to introduce, with the right brevity end emphasis, a topic which has been studied in depth by numerous experte. Nevertheless, I shall do my best to give a historical perspeotive of the subjects of the meeting which I consider to be very important for the frontiers of researoh on taurine. ~he following topios have also beoome coherent areas of study during the development of researoh on taurine: metabolism, nutrition, neurochemistry, cardiovasoular regulation. Although taurine was isolated in 1821 by ~iedman and Gmel1n, its only biochemioal role known at the time was the synthesis of bile saIte in mammalian tissue. There has been an inoreasing interest in the biologioal action of taurine from metabolio aspects to other biologioal aspects (nutrition, development, eto.). In 1975 it was first demonstrated that taurine deprivation produoed retinal degeneration in cats; more reoent studies showed that a taurine-free diet or the administration of taurine transport inhibitors caused retinal degeneration in other mammlas. More reoent studies have pointed out the role of taurine in development, and the first part of this book is dedicated to these topios


The Biology of Taurine

The Biology of Taurine
Author: Ryan J. Huxtable
Publisher:
Total Pages: 424
Release: 2014-01-15
Genre:
ISBN: 9781489904065

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Taurine 7

Taurine 7
Author: Junichi Azuma
Publisher: Springer Science & Business Media
Total Pages: 526
Release: 2008-11-05
Genre: Medical
ISBN: 0387756817

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Taurine (2-aminoethanesulfonic acid) is an enigmatic compound abounding in animal tissues. It is present at relatively high concentrations in all electrically excitable tissues such as brain, sensory organs, heart, and muscle, and in certain endocrine glands. Some of its physiological functions are already established, for example as an essential nutrient during development and as a neuromodulator or osmolyte, but the cellular mechanisms are still mostly a matter of conjecture. Moreover, there are a number of other putative functions of taurine less well known at present. Taurine 7 contains the proceedings of the 16th International Taurine Meeting. This meeting is a multidisciplinary symposium, with participants presenting different fields of biological science. This volume focuses on all aspects of taurine research from immunology and its effect on health to chemistry and biochemistry, including future clinical applications.


The Biology of Taurine

The Biology of Taurine
Author: Ryan J. Huxtable
Publisher: Springer
Total Pages: 406
Release: 1987-11-30
Genre: Medical
ISBN: 9780306426650

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Taurine in Health and Disease

Taurine in Health and Disease
Author: Ryan J. Huxtable
Publisher: Springer Science & Business Media
Total Pages: 447
Release: 2013-11-21
Genre: Science
ISBN: 1489914714

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Taurine, or 2-aminoethane sulfonic acid, has long been known to be the major organic product formed from the breakdown of the sulfur-containing amino acids, methionine and cysteine. It is excreted as such in the urine or as bile acid conjugates in the bile. Research over the last 25 years, however, has uncovered an amazing variety of phenomena involving taurine. Despite the fact that the mechanism of action of taurine in some of these phenomena remains to be elucidated, it is clear that taurine is of far more physiological relevance than being the mere metabolic debris of sulfur amino acid catabolism. It also has numerous pharmacological actions that are beginning to be developed, as exemplified by some of the studies reported in this volume. This volume reports the proceedings of the latest of a series of international symposia, continuing on from the initial meeting held in Tucson, Arizona, in 1975. The latest symposium was the first to be held in Germany, in Cologne from August 29 through September 1, 1993. It continued the multidisciplinary approach that has been the norm for taurine symposia. We hope the publication of the proceedings will stimulate further investigations on this simple but fascinating compound.


Taurine 3

Taurine 3
Author: Stephen W. Schaffer
Publisher: Springer Science & Business Media
Total Pages: 510
Release: 2013-11-11
Genre: Science
ISBN: 1489901175

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Proceedings of the International Taurine Symposium '97: Neurochemistry, Biochemistry, and Pharmacology held in Tucson, Arizona, July 15-19, 1997


Taurine 5

Taurine 5
Author: John B. Lombardini
Publisher: Springer Science & Business Media
Total Pages: 574
Release: 2012-12-06
Genre: Science
ISBN: 146150077X

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The Taurine Symposium- "Taurine: Beginning the 21'' Century"- was held September 20-23, 2002, on the beautiful island of Kauai in Hawaii. The headquarters of the meeting was the Radisson Kauai Beach Resort. This international meeting was attending by approximately 80 individuals from 23 nations and 4 continents. Seventy-five papers were presented either as platform presentations or poster presentations. Taurine, first isolated from ox bile in 1827 by Tiedemann and Gmelin and named in 1838 by Demarcay, became of significant scientific interest in 1968 when the first extensive review article was published by Jacobsen and Smith. Interest in taurine grew exponentially after 1975 when the first taurine symposium was organized by Ryan Huxtable in Tucson, Arizona. Since that date, taurine symposia have been held approximately every two years held in various cities and resort areas around the world. Taurine investigators have had the privilege of attending these scientific meetings on three continents - Asia, Europe, and North America. Since the initial meeting in 1975, a central question addressed during many of the symposia has been: "What is physiological, pharmacological, nutritional, and pathological role of taurine?". Although taurine has been established as an important osmolyte, it appears to affect many other biological processes. However, the exact mechanism(s) by "which taurine acts" has not yet been definitively answered. In Kauai, the patticipants discussed many topics and asked many questions regarding the role and actions of taurine.


Taurine 8

Taurine 8
Author: Abdeslem El Idrissi
Publisher: Springer Science & Business Media
Total Pages: 354
Release: 2013-02-11
Genre: Science
ISBN: 146146093X

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Taurine 8 represents the combined efforts of investigators on the roles of the amino acid taurine on human health and disease. The chapters covered in this book are directly derived from presentations of the contributors at the 18th International Taurine Meeting held in Marrakech, Morocco in April 2012. The purpose of this book is to disseminate current findings on taurine's contribution in several organ systems. This book covers the following topics: Taurine in Nutrition and Metabolism, the Protective Role of Taurine, and the Role of Taurine in Reproduction, Development, and Differentiation. Dr. Abdeslem El Idrissi, College of Staten Island and Dr. William L’Amoreaux, College of Staten Island, were co-chairs of the Organizing Committee for the meeting. Data presented at this meeting provided compelling evidence that taurine is not only cytoprotective in cardiomyocytes, but also is a potent GABA agonist, whereby it can facilitate vasodilation of conducting arteries. Taurine conjugates, such as taurine chloramine, may protect cells from oxidative stress via increased HO-1 expression. In adult rodents, taurine has a potent effect on plasma glucose levels, likely through the release of insulin in pancreatic beta cells. As a potential neurotransmitter, taurine is known to work via the GABAergic system, but current research presented at this meeting suggest that taurine may interact with glutamate and serotonin receptors as well. Data are also presented to demonstrate the protective roles of taurine on neurons in neuroblastoma. Perhaps the most important and exciting presentation is the role of taurine and alcohol: the combination may be lethal. Data are also presented at this meeting of the potential role taurine may have as an adjuvant treatment with cisplatin in chemotherapy.


Taurine 6

Taurine 6
Author: Simo S. Oja
Publisher: Springer Science & Business Media
Total Pages: 548
Release: 2006-10-03
Genre: Medical
ISBN: 0387335048

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Taurine (2-aminoethanesulfonic acid) is an enigmatic compound abounding in animal tissues. Some of its physiological functions are already established, but the cellular mechanisms are still mostly a matter of conjecture. The 15th International Taurine Meeting offered a multidisciplinary symposium, with participants representing a range of fields of biological science. Based on the proceedings of this meeting, Taurine 6: Taurine Today presents current research on Taurine by top scientists in the field.


Taurine 2

Taurine 2
Author: Ryan J. Huxtable
Publisher: Springer Science & Business Media
Total Pages: 631
Release: 2013-11-21
Genre: Science
ISBN: 1489901825

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This volume comprises the edited proceedings of the International Taurine Sympo sium held in Osaka, Japan, in June 1995, as a Satellite Symposium of the 15th Biennial of the International Society for Neurochemistry. This Taurine Symposium was the Meeting latest in a series held since 1975 at approximately two-year intervals by an informal group of international researchers. It attracted contributions from 20 countries, ranging from Armenia via Finland and Spain to the United States. Some 121 participants attended. The Symposium was organized and chaired by Junichi Azuma, University of Osaka. Other members of the Organizing Committee in Japan consisted of Kinya Kuriyama and Masao Nakagawa, both from the Kyoto Prefectural University of Medicine, and Akemichi Baba, from Osaka University. The Committee had to contend with the disaster of the Kobe earthquake, which struck on January 21. The epicenter was only around 25 miles from the meeting site, and the quake demolished the home of one Committee member. Despite this unnaturally natural handicap, the participants experienced a superbly organized meeting, one which more than maintained the high social and scientific standards established for this series. In his Welcome Message, Dr. Azuma listed a threefold objective for the Symposium: To provide a forum for the interdisciplinary exchange of information on taurine; to give an opportunity for renewing old friendships and making new friends; and to promote coopera tion among participants from around the world.