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| Author | : M. Mohamed Essa |
| Publisher | : Springer |
| Total Pages | : 496 |
| Release | : 2016-09-20 |
| Genre | : Medical |
| ISBN | : 3319283839 |
Download The Benefits of Natural Products for Neurodegenerative Diseases Book in PDF, ePub and Kindle
Focuses on the effects of natural products and their active components on brain function and neurodegenerative disease prevention. Phytochemicals such as alkaloids, terpenes, flavanoids, isoflavones, saponins etc are known to possess protective activity against many neurological diseases. The molecular mechanisms behind the curative effects rely mainly on the action of phytonutrients on distinct signaling pathways associated with protein folding and neuro-inflammation. The diverse array of bioactive nutrients present in these natural products plays a pivotal role in prevention and cure of various neurodegenerative diseases, disorders, or insults, such as Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, traumatic brain injury, and other neuronal dysfunctions. However, the use of these antioxidants in the management of neurodegenerative conditions has so far been not well understood. This is a comprehensive collection addressing the effects on the brain of natural products and edible items such as reservatrol, curcumin, gingerol, fruits, vegetables, nuts, and marine products.
| Author | : Cristina Angeloni |
| Publisher | : MDPI |
| Total Pages | : 338 |
| Release | : 2020-06-17 |
| Genre | : Science |
| ISBN | : 303936216X |
Download Natural Products and Neuroprotection Book in PDF, ePub and Kindle
Neurodegenerative diseases, including Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis, are the most common pathologies of the central nervous system currently without a cure. They share common molecular and cellular characteristics, including protein misfolding, mitochondrial dysfunction, glutamate toxicity, dysregulation of calcium homeostasis, oxidative stress, inflammation, and ageing, which contribute to neuronal death. Efforts to treat these diseases are often limited by their multifactorial etiology. Natural products, thanks to their multitarget activities, are considered promising alternatives for the treatment of neurodegeneration. This book deals with two different forms of natural products: extracts and isolated compounds. The study of the bioactivity of the extracts is extremely important as many studies have demonstrated the synergistic effect of the combination of different natural products. On the other hand, the investigation of the activity of specifically isolated natural products can be also important to understand their cellular and molecular mechanisms and to define the specific bioactive components in extracts or foods. This book can be considered an important contribution to knowledge of the neuroprotective effect of natural products and presents a great deal of information, related to both the benefits but also the limitations of their use in counteracting neurodegeneration.
| Author | : Goutam Brahmachari |
| Publisher | : John Wiley & Sons |
| Total Pages | : 372 |
| Release | : 2017-03-01 |
| Genre | : Medical |
| ISBN | : 3527803807 |
Download Neuroprotective Natural Products Book in PDF, ePub and Kindle
Focusing on the molecular mechanisms of powerful naturally occurring agents and their implication for drug discovery, this timely book presents an overview of the most recent research advances in the field of bioactive natural products and natural drug formulations to combat today's destructive diseases. To this extent, the authors discuss the most severe neurological disorders in our modern civilization, such as Alzheimer's, Parkinson's and Huntington's disease, as well as ischemic brain stroke and depression. The emerging diversity of active compounds is covered in detail, including flavonoids, cannabinoids and oleanolic acid, while experts in the field explain the chemistry, mode of action and clinical aspects of novel neuroprotective natural products. In each case, the benefits of treatments using natural products are addressed from the perspective of modern as well as traditional medicine. With its multidisciplinary viewpoint, this is the ideal companion for medicinal and natural products chemists as well as neuroscientists, biochemists, pharmacologists, neurobiologists, and phytotherapists.
| Author | : Cristina Angeloni |
| Publisher | : |
| Total Pages | : 338 |
| Release | : 2020 |
| Genre | : |
| ISBN | : 9783039362172 |
Download Natural Products and Neuroprotection Book in PDF, ePub and Kindle
Neurodegenerative diseases, including Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis, are the most common pathologies of the central nervous system currently without a cure. They share common molecular and cellular characteristics, including protein misfolding, mitochondrial dysfunction, glutamate toxicity, dysregulation of calcium homeostasis, oxidative stress, inflammation, and ageing, which contribute to neuronal death. Efforts to treat these diseases are often limited by their multifactorial etiology. Natural products, thanks to their multitarget activities, are considered promising alternatives for the treatment of neurodegeneration. This book deals with two different forms of natural products: extracts and isolated compounds. The study of the bioactivity of the extracts is extremely important as many studies have demonstrated the synergistic effect of the combination of different natural products. On the other hand, the investigation of the activity of specifically isolated natural products can be also important to understand their cellular and molecular mechanisms and to define the specific bioactive components in extracts or foods. This book can be considered an important contribution to knowledge of the neuroprotective effect of natural products and presents a great deal of information, related to both the benefits but also the limitations of their use in counteracting neurodegeneration.
| Author | : Preetham Elumalai |
| Publisher | : Springer Nature |
| Total Pages | : 227 |
| Release | : 2022-02-26 |
| Genre | : Medical |
| ISBN | : 9811667039 |
Download Functional Foods and Therapeutic Strategies for Neurodegenerative Disorders Book in PDF, ePub and Kindle
This book provides a comprehensive summary of the latest knowledge regarding functional foods and new therapeutic strategies for neurodegenerative disorders through explaining specific mechanisms for natural remedies and functional foods as well as alternative treatment and supplementary approaches for neurodegenerative diseases. Many relevant topics are covered, including role of prebiotics, recent applications for dietary polyphenols, marine bioactive compounds for neuro disorders, and age-related disorders. The roles of various remedies and functional foods are explained for various types of diseases, and the book also integrates the role of functional foods and remedies to work with the current therapeutics that are taking place. In parallel, the information presented through this book will also stimulate current status of leading contemporary methods for prohylactic and diagnostic practices, comprising nanoparticles, biomarkers, in silico techniques, and CRISPR-mediated genome editing–based therapy. The book will be essential reading for students and researchers with an interest in natural medicine, drug development, and food therapeutic strategies. In presenting new results and approaches and identifying areas for future research, it will also be of benefit for specialists in the field.
| Author | : Muhammad Ayaz |
| Publisher | : Frontiers Media SA |
| Total Pages | : 235 |
| Release | : 2020-01-27 |
| Genre | : |
| ISBN | : 2889633489 |
Download Natural Products-Based Drugs: Potential Therapeutics against Alzheimer's Disease and other Neurological Disorders Book in PDF, ePub and Kindle
| Author | : Yung Hou Wong |
| Publisher | : S. Karger AG (Switzerland) |
| Total Pages | : 0 |
| Release | : 2005 |
| Genre | : Natural products |
| ISBN | : 9783805579339 |
Download Natural Products for Neurodegenerative Diseases Book in PDF, ePub and Kindle
Natural products have long been used for the relief of neurological symptoms, yet their mechanisms of action remain elusive. Recent investigations have started to unveil the complex molecular events associated with the therapeutic effects of natural products in neurodegenerative diseases. In this publication, leading experts share their perspectives and latest research findings on the roles of natural products in neuroprotection and neuronal regeneration. Multifunctional properties of constituents of botanicals and their derivatives are discussed to illustrate the possibilities towards the development of effective multitarget therapeutics. Researchers in the fields of neuroscience, molecular biology, alternative medicine and pharmacology will find that this issue provides a useful overview of the various mechanisms underlying the therapeutic effects of natural products in neurodegenerative diseases.
| Author | : Goutam Brahmachari |
| Publisher | : Elsevier |
| Total Pages | : 490 |
| Release | : 2017-05-18 |
| Genre | : Science |
| ISBN | : 0128097698 |
Download Discovery and Development of Neuroprotective Agents from Natural Products Book in PDF, ePub and Kindle
Discovery and Development of Neuroprotective Agents from Natural Products draws together global research on medicinal agents from natural sources as starting points for the design of neuroprotective drugs. From the prediction of promising leads and identification of active agents to the extraction of complex molecules, the book explores a range of important topics to support the development of safer, more economical therapeutics for these increasingly prevalent diseases. Beginning with an overview of current developments in the field, the book goes on to explore the identification, extraction and phytochemistry of such neuroprotective agents as antioxidants, biophenols and naturally occurring anti-inflammatory steroid analogues. Specific natural sources of bioactive agents are reviewed, and the development of these agents into therapeutics for a number of specific neurological disorders, including Alzheimer’s disease, Parkinson’s disease and ischemic brain stroke, are discussed. Combining the expertise of specialists from around the world, this in the Natural Products Drug Discovery series aims to support and encourage researchers in the investigation of natural sources as starting points for the development of standardized, safe and effective neuroprotective drugs. Features chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery Includes comprehensive coverage of cutting-edge research advances in the design of drugs from natural products targeted at different kinds of neurodegenerative diseases Offers a practical review of identification, isolation and extraction techniques to support medicinal chemists in the lab
| Author | : Mohammad Fahad Ullah |
| Publisher | : John Wiley & Sons |
| Total Pages | : 450 |
| Release | : 2019-03-06 |
| Genre | : Science |
| ISBN | : 1119436672 |
Download Nutraceuticals and Natural Product Derivatives Book in PDF, ePub and Kindle
Introduces readers to the growing applications of nutraceuticals and other natural product derivatives This comprehensive book presents a prophylactic and therapeutic approach to chronic disease prevention strategy by highlighting the translational potential of plant-derived dietary and non-dietary factors from epidemiological, laboratory, and clinical studies. It also shares the experiences of highly reputed experts working in the area of phytomedicine and nutraceutical agents in chemoprevention, to promote the significance of natural products and dietary factors as an elite priority for containing chronic diseases in the human population. Nutraceuticals and Natural Product Derivatives: Disease Prevention & Drug Discovery starts by examining natural food sources for the control of glycemia and the prevention of diabetic complications. It then looks at the anti-aging effects of sulfur-containing amino acids and nutraceuticals, and the potential of garcinia fruits to combat metabolic syndrome. Other topics covered include honey- and propolis-mediated regulation of protein networks in cancer cells; recent trends in drug discovery against Alzheimer’s disease; the therapeutic potential of metalloherbal nanoceuticals; and much more. Offers an alternative, natural approach to the prevention of chronic diseases Emphasizes the potential of plant-derived dietary and non-dietary factors from epidemiological, laboratory, and clinical studies Features contributions from world-renowned experts in the field of phytomedicine and nutraceutical agents in chemoprevention Includes prevention strategies in normal/risk populations through routine inclusion of specific dietary regimens and as therapeutic strategy for better management through adjuvant interventions with conventional treatment protocols Nutraceuticals and Natural Product Derivatives: Disease Prevention & Drug Discovery will appeal to graduate students and professionals in cell and molecular biology, translational research, pharmacology/drug discovery, medicinal chemistry, and clinical nutrition.
| Author | : Dilip Ghosh |
| Publisher | : Academic Press |
| Total Pages | : 476 |
| Release | : 2020-11-12 |
| Genre | : Health & Fitness |
| ISBN | : 0128206101 |
Download Nutraceuticals in Brain Health and Beyond Book in PDF, ePub and Kindle
Nutraceuticals in Brain Health and Beyond focuses on a variety of health disorders where intervention with nutritional supplements prove valuable, such as Alzheimer’s, Parkinson’s, autism, and attention-deficit disorder in children. In addition, Nutraceuticals in Brain Health and Beyond addresses "herb-nutra psychiatry" which is a field of research focused on developing a comprehensive, cohesive, and scientifically rigorous evidence base to shift conceptual thinking around the role of diet and nutrition in mental health. Intended for nutrition researchers, nutritionists, dieticians, regulatory bodies, health professionals, and students studying related fields, Nutraceuticals in Brain Health and Beyond will be a useful reference in understanding the links between nutrition and brain health. • Addresses nutritional psychiatry and cognitive health at all stages of the lifespan • Contains extensive coverage of vitamins, minerals, botanicals, and other nutrients • Offers novel insight into cognitive dysfunctions including depression and other neurodegenerative disorders • Explores the role of genomics and epigenetics, including discussion of the gut–brain axis
