The African Trypanosomes PDF Download
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| Author | : Michel Dumas |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 347 |
| Release | : 2013-12-01 |
| Genre | : Medical |
| ISBN | : 2817808576 |
Download Progress in Human African Trypanosomiasis, Sleeping Sickness Book in PDF, ePub and Kindle
Human African Trypaniosomiasis (HAT) or sleeping sickness is an old disease to be now considered as reemergent. HAT is endemic in 36 sub-Saharan African countries, in areas where tsetse flies are found. The public health importance of HAT is underestimated, but the disease causes severe social disruption in many rural areas. Along the past fifteen years, numerous studies were made, and now, the mechanisms involved in the disease pathogenesis and in the characteristics of sleep-wake disruption become to be better understood. But, since 50 years, when current drugs were introduced, problems regarding HAT chemotherapy have not been solved. Nevertheless, in-depth studies about trypanosome metabolism have permitted to discover new drug targets. Written by specialists who are very experienced in their respective fields, the contributions provide an indispensable tool for practitioners and scientists.
| Author | : Samuel J. Black |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 185 |
| Release | : 2006-04-11 |
| Genre | : Science |
| ISBN | : 0306468948 |
Download The African Trypanosomes Book in PDF, ePub and Kindle
African trypanosomes are tsetse-transmitted protozoa that inhabit the extracellular compartment of host blood. They cause fatal sleeping sickness in people, and Nagana, a wasting and generally fatal disease, in cattle. While trypanosomes are most common to Africa (about 30% of Africa's cattle graze on the fringe of the tsetse habitat), some species have spread beyond its boarders to Asia, the Middle East and South America. The African Trypanosomes, volume one of World Class Parasites, is written for researchers, students and scholars who enjoy reading research that has a major impact on human health, or agricultural productivity, and against which we have no satisfactory defense. It is intended to supplement more formal texts that cover taxonomy, life cycles, morphology, vector distribution, symptoms and treatment. It integrates vector, pathogen and host biology and celebrates the diversity of approach that comprises modern parasitological research.
| Author | : Stefan Magez |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 300 |
| Release | : 2013-09-24 |
| Genre | : Medical |
| ISBN | : 3709115566 |
Download Trypanosomes and Trypanosomiasis Book in PDF, ePub and Kindle
This new volume written by experts in the field of trypanosome research covers every aspect of trypanosome-vector-host biology. It is a must read for basic researchers working with trypanosomes and related organisms, infection and drug development as well as parasitology in a broader sense.
| Author | : Ian Maudlin |
| Publisher | : CABI |
| Total Pages | : 644 |
| Release | : 2004-07-09 |
| Genre | : Medical |
| ISBN | : 9780851990347 |
Download The Trypanosomiases Book in PDF, ePub and Kindle
This state-of-the-art reference book includes comprehensive coverage of the biology and control of African, Asian and South American trypanosomiasis ("sleeping sickness") in man and animals. It describes recent research developments in the biology and molecular biology of trypanosomes (the protozoan parasite) and their vectors, and methods in diagnosis and control, such as trapping tsetse fly vectors. Different sections of the book are devoted to biology of trypanosomes, vector biology, epidemiology and diagnosis, pathogenesis, disease impact, chemotherapy and disease control, and vector control. The book contains contributions from leading experts from Europe, North and South America, and Africa.
| Author | : Sunit Kumar Singh |
| Publisher | : John Wiley & Sons |
| Total Pages | : 2365 |
| Release | : 2015-11-09 |
| Genre | : Science |
| ISBN | : 1118644646 |
Download Human Emerging and Re-emerging Infections Book in PDF, ePub and Kindle
Emerging and re-emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time-consuming process due to the “novel” nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology. Human Emerging and Re-emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public health risks posed by new viral and microbial infections. The book includes detailed coverage on the molecular mechanisms of pathogenesis, development of various diagnostic tools, diagnostic assays and their limitations, key research priorities, and new technologies in infection diagnostics. Volume 1 addresses viral and parasitic infections, while volume 2 delves into bacterial and mycotic infections. Human Emerging and Re-emerging Infections is an invaluable resource for researchers in parasitologists, microbiology, Immunology, neurology and virology, as well as clinicians and students interested in understanding the current knowledge and future directions of infectious diseases.
| Author | : Leslie Hudson |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 189 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3642705383 |
Download The Biology of Trypanosomes Book in PDF, ePub and Kindle
African and South American trypanosomiases are notable features of clinical and veterinary practice in their respective endemic areas and, as such, are of considerable economic importance. Scientifically, however, their importance ex tends beyond their clinical significance, as the trypano somes are intriguing and easily manipulated models for the study of the control of gene expression, membrane chemistry, proliferation and differentiation. It is clear from the scientific press that the rate of advance has "hotted" up in these areas of trypanosome research over the past 5 years and so a single-topic volume within the scope of the present series seemed timely. As ever, the final admix ture of review topics was a compromise between what was appropriate and what was available - fortunately with the former in vast excess. I should like to highlight two omissions, made for en tirely different reasons. The first is a detailed treatment of the molecular biology of the variant surface glycopro teins of the African trypanosomes (in particular Trypano soma brucei and T. equiperdum). This topic has been the subject of several reviews, for example, BORST and CROSS (1982)1 and TURNER (1982)2, and so was excluded from the present volume. The second omission is a review of the first-class work on genetic recombination from the group of Dr. Leo Jenni at the Schweizerisches Tropeninsti tut, Basel. This group has used isoenzyme markers to show that T.
| Author | : World Health Organization |
| Publisher | : |
| Total Pages | : 44 |
| Release | : 2019 |
| Genre | : |
| ISBN | : |
Download WHO Interim Guidelines for the Treatment of Gambiense Human African Trypanosomiasis Book in PDF, ePub and Kindle
Human African trypanosomiasis (HAT), or sleeping sickness, is a parasitic infection that is almost invariably fatal unless treated. It is a neglected tropical disease that occurs in sub-Saharan Africa. The incidence of the disease is declining in response to intensive surveillance and control in endemic areas. As a result, HAT is among the neglected tropical diseases targeted by the World Health Organization (WHO) for elimination. WHO maintains exhaustive records of all declared cases; in 2018, a historically low number of cases (less than 1000) was reported. The remarkable progress in the control of gambiense HAT has relied on case-finding and curative treatment, a strategy that interrupts transmission by depleting the reservoir of parasites in humans. This has been combined occasionally with vector control activities. The subject of these guidelines, therefore, is of utmost importance for the continuation of progress to eliminate HAT. The recent approval of a new medicine (fexinidazole) for the treatment of gambiense HAT has opened new possibilities for the management of cases and thus warrants the new WHO recommendations contained herein. While studies of fexinidazole and other therapies are ongoing, these guidelines are considered interim guidelines until new information becomes available. This document focuses on the management of patients affected by gambiense HAT and constitutes an update to the WHO therapeutic guidance issued in 2013.
| Author | : Christopher A. Sanford |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 682 |
| Release | : 2016-08-07 |
| Genre | : Medical |
| ISBN | : 0323417426 |
Download The Travel and Tropical Medicine Manual E-Book Book in PDF, ePub and Kindle
Prevent, evaluate, and manage diseases that can be acquired in tropical environments and foreign countries with The Travel and Tropical Medicine Manual. This pragmatic resource equips medical providers with the knowledge they need to offer effective aid, covering key topics in pre- and post-travel medicine, caring for immigrants and refugees, and working in low-resource settings. It's also the perfect source for travelers seeking quick, easy access to the latest travel medicine information. Dynamic images illustrate key concepts for an enhanced visual understanding. Evidence-based treatment recommendations enable you to manage diseases confidently. This eBook allows you to search all of the text, figures, images, and references from the book on a variety of devices. Highlights new evidence and content surrounding mental health and traveling. Covers emerging hot topics such as Ebola virus disease, viral hemorrhagic fevers, the role of point-of-care testing in travel medicine, and antibiotic-resistant bacteria in returning travelers and students traveling abroad. Includes an enhanced drug appendix in the back of the book.
| Author | : Maryinez Lyons |
| Publisher | : Cambridge University Press |
| Total Pages | : 356 |
| Release | : 2002-06-06 |
| Genre | : History |
| ISBN | : 9780521524520 |
Download The Colonial Disease Book in PDF, ePub and Kindle
A case-study in the history of sleeping sickness, relating it to the western 'civilising mission'.
| Author | : Gerald T. Hughes |
| Publisher | : |
| Total Pages | : 106 |
| Release | : 2016 |
| Genre | : HEALTH & FITNESS |
| ISBN | : 9781634847230 |
Download African Trypanosomiasis Book in PDF, ePub and Kindle
Human African trypanosomiasis or sleeping sickness is caused by infection with the morphologically indistinguishable subspecies Trypanosoma brucei rhodesiense (in East and Southern Africa) and Trypanosoma brucei gambiense (in West and Central Africa). The disease is presently almost under control and less than 4000 cases are currently reported. In both, T. b. rhodesiense and T. b. gambiense infection, after the injection of infective metacyclic trypanosomes with tsetse fly vector saliva, the parasites establish in the skin, differentiate to the bloodstream stage and spread via the local draining lymph node into the vascular system. In this book, Chapter One presents an overview of the current epidemiology, clinical features, diagnosis and treatment options. Chapter Two provides an in-depth review of diagnostic methods for African trypanosomiasis. Chapter Three discusses the use of aminoadamantane derivatives against Trypanosoma brucei.
