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Terahertz Imaging for Biomedical Applications

Terahertz Imaging for Biomedical Applications
Author: Xiaoxia Yin
Publisher: Springer Science & Business Media
Total Pages: 321
Release: 2012-03-23
Genre: Technology & Engineering
ISBN: 1461418208

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Terahertz biomedical imaging has become an area of interest due to its ability to simultaneously acquire both image and spectral information. Terahertz imaging systems are being commercialized, with increasing trials performed in a biomedical setting. As a result, advanced digital image processing algorithms are needed to assist screening, diagnosis, and treatment. "Pattern Recognition and Tomographic Reconstruction" presents these necessary algorithms, which will play a critical role in the accurate detection of abnormalities present in biomedical imaging. Terhazertz tomographic imaging and detection technology contributes to the ability to identify opaque objects with clear boundaries, and would be useful to both in vivo and ex vivo environments, making this book a must-read for anyone in the field of biomedical engineering and digital imaging.


Sub-Terahertz Sensing Technology for Biomedical Applications

Sub-Terahertz Sensing Technology for Biomedical Applications
Author: Shiban Kishen Koul
Publisher: Springer Nature
Total Pages: 289
Release: 2022-08-20
Genre: Science
ISBN: 9811931402

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This book offers the readers an opportunity to acquire the concepts of artificial intelligence (AI) enabled sub-THz systems for novel applications in the biomedical field. The readers will also be inspired to contextualize these applications for solving real life problems such as non-invasive glucose monitoring systems, cancer detection and dental imaging. The introductory section of this book focuses on existing technologies for radio frequency and infrared sensing in biomedical applications, and their limited use in sensing applications, as well as the advantages of using THz technology in this context. This is followed by a detailed comparative analysis of THz electronics technology and other conventional electro optic THz setups highlighting the superior efficiency, affordability and portability of electronics-based THz systems. The book also discusses electronic sub-THz measurement systems for different biomedical applications. The chapters elucidate two major applications where sub-THz provides an edge over existing state of the art techniques used for non-invasive measurement of blood glucose levels and intraoperative assessment of tumor margins. There is a detailed articulation of an application of leveraging machine learning for measurement systems for non-invasive glucose concentration measurement. This helps the reader relate to the output in a more user-friendly format and understand the possible use cases in a more lucid manner. The book is intended to help the reader learn how to build tissue phantoms and characterize them at sub-THz frequencies in order to test the measurement systems. Towards the end of the book, a brief introduction to system automation for biomedical imaging is provided as well for quick analysis of the data. The book will empower the reader to understand and appreciate the immense possibilities of using electronic THz systems in the biomedical field, creating gateways for fueling further research in this area.​


Active Terahertz Metamaterial for Biomedical Applications

Active Terahertz Metamaterial for Biomedical Applications
Author: Balamati Choudhury
Publisher: Springer
Total Pages: 63
Release: 2015-09-22
Genre: Technology & Engineering
ISBN: 9812877932

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This book describes a metamaterial-based active absorber for potential biomedical engineering applications. Terahertz (THz) spectroscopy is an important tool for imaging in the field of biomedical engineering, due to the non-invasive, non-ionizing nature of terahertz radiation coupled with its propagation characteristics in water, which allows the operator to obtain high-contrast images of skin cancers, burns, etc. without detrimental effects. In order to tap this huge potential, it is important to build highly efficient biomedical imaging systems by introducing terahertz absorbers into biomedical detectors. The biggest challenge faced in the fulfilment of this objective is the lack of naturally occurring dielectrics, which is overcome with the use of artificially engineered resonant materials, viz. metamaterials. This book describes such a metamaterial-based active absorber. The design has been optimized using particle swarm optimization (PSO), eventually resulting in an ultra-thin active terahertz absorber. The absorber shows near unity absorption for a tuning range of terahertz (THz) application.


Terahertz Biomedical Science and Technology

Terahertz Biomedical Science and Technology
Author: Joo-Hiuk Son
Publisher: CRC Press
Total Pages: 382
Release: 2014-06-13
Genre: Medical
ISBN: 146657044X

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A number of applications including scientific spectroscopy, security screening, and medical imaging have benefitted from the development and utilization of new and emerging terahertz (THz) generation and detection techniques. Exploring recent discoveries and the advancements of biological behaviors through THz spectroscopy and imaging and the development of THz medical techniques, Terahertz Biomedical Science and Technology contains contributions from scientists and researchers in the terahertz biomedical field and is exclusively dedicated to new and emerging terahertz biomedical research and applications. This text offers an assessment of terahertz technology, and provides a compilation of fundamental biological studies conducted using terahertz waves. It introduces THz electromagnetic waves as a new tool for convergent studies, includes laser-based generation techniques and solid-state devices, contains a number of detectors, and discusses high-field generation methods. The material covers recent advancements in terahertz imaging for medical applications—most specifically in cancer diagnosis—reviewing the current status of the THz imaging technique for diagnosing cancers, and exploring the potential medical applications of THz radiation. It also considers the development of future medical applications using terahertz technology. Summarizes the recent progress made in THz waveguides, which are absolutely essential in the development of THz endoscopes Describes the dynamic imaging of drug absorption in skin, exploiting the sensitivity of THz waves to pharmaceutical materials Explores the principle and applications of THz molecular imaging techniques using nanoparticle probes Scientists and engineers involved in biological research and medical applications using optical techniques, as well as graduate students and instructors in optics, physics, electrical engineering, biology, chemistry, and medicine can benefit from this text which highlights new and emerging biomedical studies utilizing novel THz wave techniques.


Terahertz Spectroscopic Characterization and Imaging for Biomedical Applications

Terahertz Spectroscopic Characterization and Imaging for Biomedical Applications
Author: Woon-Gi Yeo
Publisher:
Total Pages: 132
Release: 2015
Genre:
ISBN:

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Subsequently, the sensitivity of THz waves to tissue hydration is quantified through freshly-excised tissue samples. We demonstrate that cancer margins can also be accurately characterized using the differences in tissue hydration. The study is expanded to include human lung and small intestine tissues with malignant regions. New image processing algorithms are developed to enhance THz image contrast and localization of malignant areas. Furthermore, a THz polarimetry is introduced to increase sensitivity of cancer margin identification and its performance is demonstrated through full-wave simulations. Finally, human brain tissues exhibiting Alzheimer's disease are investigated to demonstrate the utility of THz imaging in Alzheimer's detection. We quantify, for the first time, measurable differences in THz reflectivity of gray and white matter, leading to accurate post-mortem diagnosis of Alzheimer's disease. Furthermore, we hypothesize that the reason for the reflectivity contrast is due to demyelination of axons. To support this hypothesis, we present full-wave electromagnetic simulations of a simplified axon model and compare the simulation data with THz measurements. Although this initial study demonstrates the efficacy of THz sensing in Alzheimer's detection, more case studies are needed to establish this finding as a viable clinical biomarker in the Alzheimer's detection in early stage.


Terahertz Antenna Technology for Imaging and Sensing Applications

Terahertz Antenna Technology for Imaging and Sensing Applications
Author: Isha Malhotra
Publisher: Springer Nature
Total Pages: 321
Release: 2021-05-11
Genre: Technology & Engineering
ISBN: 3030689603

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This book covers terahertz antenna technology for imaging and sensing, along with its various applications. The authors discuss the use of terahertz frequency and photoconductive antenna technology for imaging applications, such as biological and bio-medical applications, non-destructive inspection of fabrics and plastics, analysis of hydration levels or detecting the presence of metallic components in samples, and detecting a variety of materials with unique spectral fingerprints in the terahertz frequency range, such as different types of explosives or several compounds used in the fabrication of medicines. Provides a comprehensive review of terahertz source and detector for imaging and sensing; Discusses photoconductive antenna technology for imaging and sensing; Presents modalities for improving the photoconductive dipole antenna performance for imaging and sensing; Explores applications in tomographic imaging, art conservation and the pharmaceutical and aerospace industries.


Terahertz Biomedical Science and Technology

Terahertz Biomedical Science and Technology
Author: Joo-Hiuk Son
Publisher:
Total Pages: 357
Release: 2014-01-01
Genre: Diagnostic imaging
ISBN: 9781306865906

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"This book focuses on biomedical applications of terahertz (THz) waves. THz waves offer advantages due to their low energy (greater safety), long wavelength (higher resolution), and sensitivity to water molecules. The book explores the use of THz spectroscopy in elucidating biological behaviors as well as the development of THz wave medical techniques, such as skin drug absorption imaging and cancer diagnosis. It also includes an overview of THz technology, encompassing generation, detection, and imaging methods"--Provided by publisher.


Terahertz Biomedical and Healthcare Technologies

Terahertz Biomedical and Healthcare Technologies
Author: Amit Banerjee
Publisher: Elsevier
Total Pages: 262
Release: 2020-09-01
Genre: Technology & Engineering
ISBN: 0128185562

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Terahertz Biomedical and Healthcare Technologies: Materials to Devices reviews emerging advances in terahertz biomedical and healthcare technologies, including advances in fundamental materials science research, device design and fabrication, applications, and challenges and opportunities for improved performance. In addition, the improvement of materials, optical elements, and measuring techniques are also explored. Other sections cover the design and development of wide bandgap semiconductors for terahertz device applications, including their physics, device modeling, characterization and fabrication concepts. Finally, the book touches on potential defense, medical imaging, internet of things, and the machine learning applications of terahertz technologies. Reviews the latest advances in the fundamental and applied research of terahertz technologies, covering key topics in materials science, biomedical engineering and healthcare informatics Includes applications of terahertz technologies in medical imaging, diagnosis and treatment Provides readers with an understanding of the machine learning, pattern recognition, and data analytics research utilized to enhance the effectiveness of terahertz technologies


Convergence of Terahertz Sciences in Biomedical Systems

Convergence of Terahertz Sciences in Biomedical Systems
Author: Gun-Sik Park
Publisher: Springer Science & Business Media
Total Pages: 428
Release: 2012-10-19
Genre: Technology & Engineering
ISBN: 9400739648

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Recent technological breakthrough in the field of Terahertz radiation has triggered new applications in biology and biomedicine. Particularly, biological applications are based on the specific spectroscopic fingerprints of biological matter in this spectral region. Historically with the discovery of new electromagnetic wave spectrum, we have always discovered new medical diagnostic imaging systems. The use of terahertz wave was not realized due to the absence of useful terahertz sources. Now after successful generation of THz waves, it is reported that a great potential for THz wave exists for its resonance with bio-molecules. There are many challenging issues such as development of THz passive and active instrumentations, understanding of THz-Bio interaction for THz spectroscopy, THz-Bio nonlinear phenomena and safety guideline, and THz imaging systems. Eventually the deeper understanding of THz-Bio interaction and novel THz systems enable us to develop powerful THz biomedical imaging systems which can contribute to biomedical industry. This is a truly interdisciplinary field and convergence technology where the communication between different disciplines is the most challenging issue for the success of the great works. One of the first steps to promote the communications in this convergence technology would be teaching the basics of these different fields to the researchers in a plain language with the help of Convergence of Terahertz Science in Biomedical Systems which is considered to be 3-4th year college students or beginning level of graduate students. Therefore, this type of book can be used by many people who want to enter or understand this field. Even more it can be used for teaching in universities or research institutions.


Terahertz Technology

Terahertz Technology
Author: T. Anukiruthika
Publisher: CRC Press
Total Pages: 312
Release: 2023-08-22
Genre: Technology & Engineering
ISBN: 1000914402

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Terahertz (THz) technology is an active area of research, but only in recent years has the application of THz waves (T waves) in food and agricultural industries been explored. Terahertz Technology: Principles and Applications in the Agri-Food Industry describes the operating principles of THz technology and discusses applications and advantages of the THz regime of the electromagnetic spectrum for use in the agri-food industry. The agri-food industry is focusing on the development of non-destructive quality evaluation techniques that can provide accurate analysis quickly and are environmentally friendly. Among such techniques is THz technology that provides a novel noninvasive approach to quality assessment and safety assurance of agri-food products. The low energy of T waves is best suited for the analysis of sensitive biomaterials and does not cause photoionization. Therefore, THz imaging is complementary to X-ray imaging. Although accessing the THz spectrum is tedious by conventional devices, the combination of optics and electronics principles has opened a dimension of research in this field. This book provides an overview of THz spectroscopy and imaging, system components, types of THz systems, and applications and advantages of THz for applications in the agri-food industry. It describes the basic working mechanism, operating principle, operation modes, and system components of THz spectroscopy and imaging. Various advancements in THz technology related to agricultural and food applications are discussed that could serve as a guidebook for all those working and interested in non-destructive food assessment techniques. Key Features: Explores broader applications of the THz regime in the agri-food sector Describes system components, different forms of THz systems, and the working principle of T waves for spectroscopic and imaging techniques Provides insights on future research needs for industrial implementation of THz technology Complements the knowledge of other existing non-destructive spectroscopy and imaging techniques for food analysis Although books on biomedical applications of THz have been published, no book is available that deals with applications in the agri-food industry. Hence, Terahertz Technology is beneficial for undergraduate and graduate students and those food industry professionals involved in research related to non-destructive quality assessment and imaging techniques.