Synthetic Peptides And Peptidomimetics From Basic Science To Biomedical Applications PDF Download
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Author | : Nunzianna Doti |
Publisher | : Mdpi AG |
Total Pages | : 0 |
Release | : 2022-06-10 |
Genre | : Science |
ISBN | : 9783036543963 |
Download Synthetic Peptides and Peptidomimetics Book in PDF, ePub and Kindle
This Special Issue, entitled "Synthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications", has included both reviews and original research contributions focused on the chemical design and biomedical applications of structurally modified bioactive peptides. The papers collected show how successful this class of molecules still is, both as model molecules for studying the structure of proteins and as potential therapeutics and diagnostics, and also as laboratory tools for advanced basic and applied studies. The large scientific community working in this field is in fact very active and productive, and is making the most of the potential and versatility of these molecules to generate increasingly interesting and innovative molecules of therapeutic interest and to understand the fundamental molecular mechanisms of life.
Author | : Nunzianna Doti |
Publisher | : |
Total Pages | : 0 |
Release | : 2022 |
Genre | : |
ISBN | : 9783036543956 |
Download Synthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications Book in PDF, ePub and Kindle
This Special Issue, entitled "Synthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications", has included both reviews and original research contributions focused on the chemical design and biomedical applications of structurally modified bioactive peptides. The papers collected show how successful this class of molecules still is, both as model molecules for studying the structure of proteins and as potential therapeutics and diagnostics, and also as laboratory tools for advanced basic and applied studies. The large scientific community working in this field is in fact very active and productive, and is making the most of the potential and versatility of these molecules to generate increasingly interesting and innovative molecules of therapeutic interest and to understand the fundamental molecular mechanisms of life.
Author | : Alessandro Contini |
Publisher | : Frontiers Media SA |
Total Pages | : 145 |
Release | : 2019-09-26 |
Genre | : |
ISBN | : 2889630455 |
Download Folded Synthetic Peptides for Biomedical Applications Book in PDF, ePub and Kindle
Folded peptides - and peptide motifs within proteins - are abundant in living organisms, where they are essential for the biological activities of the peptides and proteins. During the past decades, much research has been dedicated to understanding the rules that govern peptide folding. Simultaneously, a range of strategies have been established for the conformational stabilization of bioactive peptides, as well as for the de novo design of peptides with defined secondary structures. These methods are either based on the chemical modification of the peptide backbone, such as cyclization and stapled peptides, or on the use of a range of non-proteinogenic amino acids that, in a defined sequential arrangement, induce secondary structures peptides. Such building blocks include D- and other non-proteinogenic amino acids, as well as beta- and gamma-amino acids. This Research Topic comprises a collection of papers by an international group of 77 scientists with a background in synthetic, analytical, computational and medicinal chemistry, as well as in biochemistry and pharmacology. Their research is presented here in a total of 11 papers (8 original research reports and 3 reviews), covering diverse aspects of folded synthetic peptides. These studies include the preparation and characterization of new peptide monomers with interesting folding properties, the synthesis and conformational analysis of non-natural peptides, as well as the use of folded peptidomimetics as molecular switches. Additionally, a range of biomedical applications, such as antimicrobial, anti-inflammatory, antiangiogenic and immune-stimulating activities, are also reported. We hope this eBook will be a source of inspiration and knowledge for scientist in various disciplines related to folded peptides and their many applications, as well as for those who want to learn more about this fascinating field of research.
Author | : Henry I. Mosberg |
Publisher | : MDPI |
Total Pages | : 406 |
Release | : 2020-03-13 |
Genre | : Medical |
ISBN | : 3039282883 |
Download Advances in Peptide and Peptidomimetic Design Inspiring Basic Science and Drug Discovery Book in PDF, ePub and Kindle
Advances in Peptide and Peptidomimetic Design Inspiring Basic Science and Drug Discovery is a book dedicated to Prof. Victor J. Hruby on the occasion of his 80th birthday. This book includes twenty contributions from authors representing diverse multidisciplinary fields of scientific expertise, and is focused on the extraordinary potential of peptides and peptidomimetics as a surging therapeutic modality and as tools for basic research and technology development.
Author | : David B. Weiner |
Publisher | : CRC Press |
Total Pages | : 382 |
Release | : 1993-11-04 |
Genre | : Medical |
ISBN | : 9780877629351 |
Download Biologically Active Peptides Book in PDF, ePub and Kindle
Investigation into basic and advanced peptide design, synthesis, evaluation and utilization. New therapeutic approaches from experimental systems.
Author | : David B. Weiner |
Publisher | : CRC Press |
Total Pages | : 377 |
Release | : 2023-07-28 |
Genre | : Medical |
ISBN | : 1000942929 |
Download Biologically Active Peptides Book in PDF, ePub and Kindle
Investigation into basic and advanced peptide design, synthesis, evaluation and utilization. New therapeutic approaches from experimental systems.
Author | : Antonio Guarna |
Publisher | : John Wiley & Sons |
Total Pages | : 334 |
Release | : 2014-03-14 |
Genre | : Science |
ISBN | : 1118683145 |
Download Peptidomimetics in Organic and Medicinal Chemistry Book in PDF, ePub and Kindle
A peptidomimetic is a small protein-like chain designed to mimic a peptide with adjusted molecular properties such as enhanced stability or biological activity. It is a very powerful approach for the generation of small-molecule-based drugs as enzyme inhibitors or receptor ligands. Peptidomimetics in Organic and Medicinal Chemistry outlines the concepts and synthetic strategies underlying the building of bioactive compounds of a peptidomimetic nature. Topics covered include the chemistry of unnatural amino acids, peptide- and scaffold-based peptidomimetics, amino acid-side chain isosteres, backbone isosteres, dipeptide isosteres, beta-turn peptidomimetics, proline-mimetics as turn inducers, cyclic scaffolds, amino acid surrogates, and scaffolds for combinatorial chemistry of peptidomimetics. Case studies in the hit-to-lead process, such as the development of integrin ligands and thrombin inhibitors, illustrate the successful application of peptidomimetics in drug discovery.
Author | : Carrie Haskell-Luevano |
Publisher | : |
Total Pages | : 406 |
Release | : 2020 |
Genre | : Medicine (General) |
ISBN | : 9783039282890 |
Download Advances in Peptide and Peptidomimetic Design Inspiring Basic Science and Drug Discovery: A Themed Issue Honoring Professor Victor J. Hruby on the Occasion of His 80th Birthday Book in PDF, ePub and Kindle
Advances in Peptide and Peptidomimetic Design Inspiring Basic Science and Drug Discovery is a book dedicated to Prof. Victor J. Hruby on the occasion of his 80th birthday. This book includes twenty contributions from authors representing diverse multidisciplinary fields of scientific expertise, and is focused on the extraordinary potential of peptides and peptidomimetics as a surging therapeutic modality and as tools for basic research and technology development.
Author | : Sotirios Koutsopoulos |
Publisher | : Woodhead Publishing |
Total Pages | : 655 |
Release | : 2017-11-16 |
Genre | : Technology & Engineering |
ISBN | : 0081007426 |
Download Peptide Applications in Biomedicine, Biotechnology and Bioengineering Book in PDF, ePub and Kindle
Peptide Applications in Biomedicine, Biotechnology and Bioengineering summarizes the current knowledge on peptide applications in biomedicine, biotechnology and bioengineering. After a general introduction to peptides, the book addresses the many applications of peptides in biomedicine and medical technology. Next, the text focuses on peptide applications in biotechnology and bioengineering and reviews of peptide applications in nanotechnology. This book is a valuable resource for biomaterial scientists, polymer scientists, bioengineers, mechanical engineers, synthetic chemists, medical doctors and biologists. Presents a self-contained work for the field of biomedical peptides Summarizes the current knowledge on peptides in biomedicine, biotechnology and bioengineering Covers current and potential applications of biomedical peptides
Author | : |
Publisher | : Elsevier |
Total Pages | : 400 |
Release | : 2024-06-28 |
Genre | : Science |
ISBN | : 0443218153 |
Download Peptide and Peptide Mimicking Tools: Methods, Synthesis, Design & Applications Book in PDF, ePub and Kindle
Peptide Chemical Tools for Modulating Biology, Volume 698 in the esteemed Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting topics on Peptide tools that target telomere maintenance, Molecular Design of Peptide Therapeutics, Sulfonyl peptide tools for modulating biology, Peptide tools for targeting the Crk/CrkL-p130Cas axis, Quorum sensing peptide tools, In vivo stability and BBB penetration of peptide tools, and Oligo-benzamide-based peptide mimicking tools for modulating biology. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Methods in Enzymology Updated release includes the latest information on Peptide Chemical Tools for Modulating Biology