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Synapse 2014

Synapse 2014
Author: The Student's Council, Kilpauk Medical College
Publisher: The Student's Council, Kilpauk Medical College
Total Pages: 136
Release: 2015-04-06
Genre:
ISBN:

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The Annual Magazine published by the Student's Council of Kilpauk Medical College, highlighting all the events of the year. This includes Vaanavil - The Intracollege Cultural Fiesta Medrenaline - One of the biggest Medical Conference of Tamil Nadu Aadukalam - One of the biggest Inter - Medical Sports event of the state Pradharshini - The biggest Culturals conducted by a Medical College There are also several articles by the future doctors of Kilpauk Medical College, regarding a plethora of topics. So just pick up the book and enjoy :)


Synapse Development and Maturation

Synapse Development and Maturation
Author: Pasko Rakic
Publisher: Academic Press
Total Pages: 560
Release: 2020-05-29
Genre: Psychology
ISBN: 0128236736

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Synapse Development and Maturation, the latest release in the Comprehensive Developmental Neuroscience series, presents the latest information on the genetic, molecular and cellular mechanisms of neural development. The book provides a much-needed update that underscores the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on the synaptogenesis and developmental sequences in the maturation of intrinsic and synapse-driven patterns. Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Includes coverage of mechanisms which regulate synapse formation and maintenance during development Covers neural activity, from cell-intrinsic maturation, to early correlated patterns of activity


Imaging Synapse Structure and Function

Imaging Synapse Structure and Function
Author: George J. Augustine
Publisher: Frontiers Media SA
Total Pages: 127
Release: 2017-07-06
Genre:
ISBN: 2889451755

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Development of new imaging technologies in recent years has transformed neuroscience in profound ways. Following on the heels of the revolution based on the Green Fluorescent Protein, refined genetically-encoded fluorescent reporters and genetic targeting strategies now enable optical recording of synaptic transmission in defined neuronal populations at speeds approaching the enviable temporal resolution of electrophysiology. Super-resolution light microscopy permits observation of synapses and their molecular machinery at sub-diffraction resolution. At the ultrastructural level, automated forms of electron microscopy, improvements in specimen fixation methods, and recent efforts to correlate data from light and electron micrographs now make the reconstruction of functional neural circuits a reality. Finally, the use of optogenetic actuators, such as channelrhodopsins, allows precise temporal and spatial manipulation of neuronal activity and is revealing profound insights into the organization of neural circuits and their roles in behavior. This research topic highlights recent advances in both light and electron microscopy, with a specific focus on approaches that combine innovations from several different fields to obtain novel information about synapse structure and function. We are confident that this collection of articles - three original research papers, six reviews, one methods paper and one perspective article - will enable neuroscientists to achieve the next generation of experiments aimed at cracking the neural code.


Enabling Technologies for Very Large-Scale Synaptic Electronics

Enabling Technologies for Very Large-Scale Synaptic Electronics
Author: Themis Prodromakis
Publisher: Frontiers Media SA
Total Pages: 105
Release: 2018-07-05
Genre:
ISBN: 2889455084

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An important part of the colossal effort associated with the understanding of the brain involves using electronics hardware technology in order to reproduce biological behavior in ‘silico’. The idea revolves around leveraging decades of experience in the electronics industry as well as new biological findings that are employed towards reproducing key behaviors of fundamental elements of the brain (notably neurons and synapses) at far greater speed-scale products than any software-only implementation can achieve for the given level of modelling detail. So far, the field of neuromorphic engineering has proven itself as a major source of innovation towards the ‘silicon brain’ goal, with the methods employed by its community largely focused on circuit design (analogue, digital and mixed signal) and standard, commercial, Complementary Metal-Oxide Silicon (CMOS) technology as the preferred `tools of choice’ when trying to simulate or emulate biological behavior. However, alongside the circuit-oriented sector of the community there exists another community developing new electronic technologies with the express aim of creating advanced devices, beyond the capabilities of CMOS, that can intrinsically simulate neuron- or synapse-like behavior. A notable example concerns nanoelectronic devices responding to well-defined input signals by suitably changing their internal state (‘weight’), thereby exhibiting `synapse-like’ plasticity. This is in stark contrast to circuit-oriented approaches where the `synaptic weight’ variable has to be first stored, typically as charge on a capacitor or digitally, and then appropriately changed via complicated circuitry. The shift of very much complexity from circuitry to devices could potentially be a major enabling factor for very-large scale `synaptic electronics’, particularly if the new devices can be operated at much lower power budgets than their corresponding 'traditional' circuit replacements. To bring this promise to fruition, synergy between the well-established practices of the circuit-oriented approach and the vastness of possibilities opened by the advent of novel nanoelectronic devices with rich internal dynamics is absolutely essential and will create the opportunity for radical innovation in both fields. The result of such synergy can be of potentially staggering impact to the progress of our efforts to both simulate the brain and ultimately understand it. In this Research Topic, we wish to provide an overview of what constitutes state-of-the-art in terms of enabling technologies for very large scale synaptic electronics, with particular stress on innovative nanoelectronic devices and circuit/system design techniques that can facilitate the development of very large scale brain-inspired electronic systems


Artificial Life and Computational Intelligence

Artificial Life and Computational Intelligence
Author: Tapabrata Ray
Publisher: Springer
Total Pages: 380
Release: 2016-01-22
Genre: Computers
ISBN: 3319282700

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This book constitutes the proceedings of the Second Australasian Conference on Artificial Life and Computational Intelligence, ACALCI 2016, held in Canberra, ACT, Australia, in February 2016. The 30 full papers presented in this volume were carefully reviewed and selected from 41 submissions. They are organized in topical sections named: mathematical modeling and theory; learning and optimization; planning and scheduling; feature selection; and applications and games.


The Genetics of Neurodevelopmental Disorders

The Genetics of Neurodevelopmental Disorders
Author: Kevin J. Mitchell
Publisher: John Wiley & Sons
Total Pages: 384
Release: 2015-08-04
Genre: Medical
ISBN: 1118524977

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Neurodevelopmental disorders arise from disturbances to various processes of brain development, which can manifest in diverse ways. They encompass many rare genetic syndromes as well as common, heritable conditions such as intellectual disability, autism, ADHD, schizophrenia and many types of epilepsy. The Genetics of Neurodevelopmental Disorders examines recent revolutionary advances in our understanding of the genetics of these disorders, exploring both basic discoveries and the translation of new findings into the clinical setting. The book begins by examining the genetic architecture and etiology of neurodevelopmental disorders. It describes the striking recent progress in identifying pathogenic mutations, which are grouped here based on the neurodevelopmental processes impacted. Subsequent chapters consider the use of cellular and animal models to elucidate the cascading consequences of such mutations, from molecular and cellular levels to emergent effects on neural circuits, brain systems and subsequent psychological development. The text concludes by examining the important clinical implications of the recent advances in the field, from recognition of the genetic causes in individual patients to development of new treatments and interventions. A timely synthesis, The Genetics of Neurodevelopmental Disorders is a unique and essential resource for neuroscientists, geneticists, neurologists and psychiatrists and an accessible and up-to-date overview for medical and science students.


Hybrid PET/MR Neuroimaging

Hybrid PET/MR Neuroimaging
Author: Ana M. Franceschi
Publisher: Springer Nature
Total Pages: 848
Release: 2021-11-30
Genre: Medical
ISBN: 3030823679

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This book serves as a reference and comprehensive guide for PET/MR neuroimaging. The field of PET/MR is rapidly evolving, however, there is no standard resource summarizing the vast information and its potential applications. This book will guide neurological molecular imaging applications in both clinical practice and the research setting. Experts from multiple disciplines, including radiologists, researchers, and physicists, have collaborated to bring their knowledge and expertise together. Sections begin by covering general considerations, including public health and economic implications, the physics of PET/MR systems, an overview of hot lab and cyclotron, and radiotracers used in neurologic PET/MRI. There is then coverage of each major disease/systemic category, including dementia and neurodegenerative disease, epilepsy localization, brain tumors, inflammatory and infectious CNS disorders, head and neck imaging, as well as vascular hybrid imaging. Together, we have created a thorough, concise and up-to-date textbook in a unique, user-friendly format. This is an ideal guide for neuroradiologists, nuclear medicine specialists, medical physicists, clinical trainees and researchers.


Concussion and Traumatic Encephalopathy

Concussion and Traumatic Encephalopathy
Author: Jeff Victoroff
Publisher: Cambridge University Press
Total Pages: 895
Release: 2019-02-28
Genre: Medical
ISBN: 1107073952

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Readers will discover how very recent scientific advances have overthrown a century of dogma about concussive brain injury.