Studies On Metabolism And Biochemical Effects Of Tetraethylthiuram Disulphide Disulfiram And Diethyldithiocarbamate PDF Download
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Author | : Johan H. Strömme |
Publisher | : |
Total Pages | : 72 |
Release | : 1964 |
Genre | : |
ISBN | : |
Download Studies on Metabolism and Biochemical Effects of Tetraethylthiuram Disulphide '(disulfiram)' and Diethyldithiocarbamate Book in PDF, ePub and Kindle
Author | : P.K. Gessner |
Publisher | : Springer Science & Business Media |
Total Pages | : 461 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 9401123284 |
Download Disulfiram and its Metabolite, Diethyldithiocarbamate Book in PDF, ePub and Kindle
This book is aimed at those in the biomedical community that are interested in the therapeutic applications, pharmacology, biochemistry, toxicology and pharmacokinetics of the title compounds. Recent findings regarding the ability of diethyldithiocarbamate (ditiocarb, Imuthiol®) to delay the progression of HN infections and AIDS, the discovery of its potential as a rescue agent in cancer chemotherapy, and the identification of disulfiram (Antabuse®) regimens that allow alcoholics to achieve abstinence of many months' duration have made writing this book an exciting experience. At the same time the fact that the two drugs differ substantially in their pharmacological effects in spite of their easy interconvertibility has rendered the writing intellec tually challenging. Diethyldithiocarbamate, an agent seemingly less toxic than aspirin, rivals it in the multiplicity and diversity of its pharmacological proper ties. Notable among these are the manyfold potent immunostimulant effects, and though most of these involve effects on T -cells, the mechanism of diethyldithiocarbamate's action remains far from clear. The drug is also a potent chelator of heavy metals and this has led to a number of clinical applications. As might be expected, it inhibits several important enzymes. Further, it is one of the most effective radioprotective agents; it also protects organisms against a variety of toxic agents.
Author | : National Library of Medicine (U.S.) |
Publisher | : |
Total Pages | : 1550 |
Release | : |
Genre | : Medicine |
ISBN | : |
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First multi-year cumulation covers six years: 1965-70.
Author | : |
Publisher | : |
Total Pages | : 942 |
Release | : 1970 |
Genre | : Psychopharmacology |
ISBN | : |
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Author | : |
Publisher | : |
Total Pages | : 1422 |
Release | : 1989 |
Genre | : Medicine |
ISBN | : |
Download Cumulated Index Medicus Book in PDF, ePub and Kindle
Author | : |
Publisher | : |
Total Pages | : 766 |
Release | : 1970 |
Genre | : Pharmacology |
ISBN | : |
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Author | : Paul G. Pearson |
Publisher | : CRC Press |
Total Pages | : 755 |
Release | : 2019-05-20 |
Genre | : Medical |
ISBN | : 1482262045 |
Download Handbook of Drug Metabolism, Third Edition Book in PDF, ePub and Kindle
This book continues to be the definitive reference on drug metabolism with an emphasis on new scientific and regulatory developments. It has been updated based on developments that have occurred in the last 5 years, with new chapters on large molecules disposition, stereo-selectivity in drug metabolism, drug transporters and metabolic activation of drugs. Some chapters have been prepared by new authors who have emerged as subject area experts in the decade that has passed since publication of the first edition.
Author | : Morris S. Zedeck |
Publisher | : Springer Science & Business Media |
Total Pages | : 242 |
Release | : 2013-11-21 |
Genre | : Social Science |
ISBN | : 1461592186 |
Download Inhibition of Tumor Induction and Development Book in PDF, ePub and Kindle
The primary purpose of this book is to bring to the attention of members of the medical and scientific communities, as well as to other interested persons, a new and expanding area of investigation that features the use of chemicals for the prevention of tumor induction and development. This novel use of chemical compounds has succeeded in producing a remarkable series of discoveries in recent years. Some of these are beginning to be evaluated in the field of clinical oncology in a manner that has potentially enormous public health implications. It is anticipated, therefore, that increasing amounts of time, energy, and financial resources will be devoted to the further development and expansion of this work. The major contribution of this book at the present time is that it summarizes and brings up to date the pioneering efforts of the various scientists who originated this new and exciting field of scientific activity. The thoughts expressed by Louis Pasteur in 1884 may soon be applicable in the fight against cancer: "When meditating over a disease, I never think of finding a remedy for it, but instead a means of preventing it. " The emphasis on cancer prevention currently underway is the result, in part, of an increased awareness that the environment-geographical, cultural, and occupational-has a role in development of the disease.
Author | : |
Publisher | : |
Total Pages | : 1264 |
Release | : 1978 |
Genre | : Biochemistry |
ISBN | : |
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Vols. 36- include Proceedings of the Biochemical Society.
Author | : Garth Powis |
Publisher | : Taylor & Francis Group |
Total Pages | : 360 |
Release | : 1987 |
Genre | : Medical |
ISBN | : |
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