Structural Studies Of Protein Nucleic Acid Interaction PDF Download
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Author | : Thomas A. Steitz |
Publisher | : CUP Archive |
Total Pages | : 108 |
Release | : 1993-09-16 |
Genre | : Science |
ISBN | : 9780521414890 |
Download Structural Studies of Protein-Nucleic Acid Interaction Book in PDF, ePub and Kindle
In this 1993 text, Nobel Prize winner Professor Steitz reviews the wide-ranging research in structural studies of DNA-binding proteins and their complexes with DNA. The author clearly and concisely describes the uses of techniques in molecular genetics, DNA synthesis, protein crystallography and nuclear magnetic response.
Author | : Phoebe A. Rice |
Publisher | : Royal Society of Chemistry |
Total Pages | : 417 |
Release | : 2008-05-22 |
Genre | : Science |
ISBN | : 0854042725 |
Download Protein-Nucleic Acid Interactions Book in PDF, ePub and Kindle
This book provides both in-depth background and up-to-date information in this area. The chapters are organized by general themes and principles, written by experts who illustrate topics with current findings. Topics covered include: - the role of ions and hydration in protein-nucleic acid interactions - transcription factors and combinatorial specificity - indirect readout of DNA sequence - single-stranded nucleic acid binding proteins - nucleic acid junctions and proteins, - RNA protein recognition - recognition of DNA damage. It will be a key reference for both advanced students and established scientists wishing to broaden their horizons.
Author | : Wolfram Saenger |
Publisher | : |
Total Pages | : 230 |
Release | : 1989 |
Genre | : Science |
ISBN | : |
Download Protein-nucleic Acid Interaction Book in PDF, ePub and Kindle
This volume contains a series of essays which describe a range of problems in the field of nucleic-acid interactions, investigated by a variety of techniques. An introductory chapter on DNA-protein interactions in the regulation of gene expression is followed by papers on selected model systems.
Author | : Shu Fen Wang |
Publisher | : |
Total Pages | : 342 |
Release | : 1997 |
Genre | : |
ISBN | : |
Download Structural Studies of Protein Nucleic Acid Interactions Book in PDF, ePub and Kindle
Author | : Bruce Alberts |
Publisher | : |
Total Pages | : 0 |
Release | : 2002 |
Genre | : Cytology |
ISBN | : 9780815332183 |
Download Molecular Biology of The Cell Book in PDF, ePub and Kindle
Author | : Jost |
Publisher | : Birkhäuser |
Total Pages | : 319 |
Release | : 2013-03-13 |
Genre | : Science |
ISBN | : 3034875614 |
Download A Laboratory Guide to In Vitro Studies of Protein-DNA Interactions Book in PDF, ePub and Kindle
A Safety Considerations Many techniques described here involve a number of hazards, such as high electrical current and voltage, radioactivity and highly toxic chemicals. It is absolutely essential that the instructions of equipment manufacturers be followed, and that particular attention be paid to the local and federal safety regulations. B Introduction The expression of prokaryotic and eukaryotic genes has been shown most often to be regulated at the level of mRNA synthesis. Thanks to the rapid development of methods for dissecting DNA sequences, cis-acting regulatory elements such as promoters and enhancers have been recognised. More recently, the widely expressed intuition that discrete sequences within these elements constitute binding sites for sequence-specific binding proteins has been confirmed, especially through the use of "footprinting" assays (for examples, Galas and Schmitz, 1978). This and similar assays have already resulted in the recognition, isolation and analysis of DNA-bind ing proteins for several genes. Excellent reviews exist of the structural studies on these transcription regulatory proteins and related DNA elements (for example, Glover, 1989 and Johnson and McKnight, 1989), to which the reader is referred for detailed information. To set the scene for applications of the techniques described in this volume, only the barest outline of previous studies is presented here. Protein-DNA interactions are dependent on very specific tertiary configurations of the binding protein which allow the closest contact with the DNA helix.
Author | : Erwin J. G. Peterman |
Publisher | : Humana Press |
Total Pages | : 317 |
Release | : 2011-09-15 |
Genre | : Science |
ISBN | : 9781617792816 |
Download Single Molecule Analysis Book in PDF, ePub and Kindle
Life scientists believe that life is driven, directed, and shaped by biomolecules working on their own or in concert. It is only in the last few decades that technological breakthroughs in sensitive fluorescence microscopy and single-molecule manipulation techniques have made it possible to observe and manipulate single biomolecules and measure their individual properties. The methodologies presented in Single Molecule Techniques: Methods and Protocols are being applied more and more to the study of biologically relevant molecules, such as DNA, DNA-binding proteins, and motor proteins, and are becoming commonplace in molecular biophysics, biochemistry, and molecular and cell biology. The aim of Single Molecule Techniques: Methods and Protocols is to provide a broad overview of single-molecule approaches applied to biomolecules on the basis of clear and concise protocols, including a solid introduction to the most widely used single-molecule techniques, such as optical tweezers, single-molecule fluorescence tools, atomic force microscopy, magnetic tweezers, and tethered particle motion. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Single Molecule Techniques: Methods and Protocols serves as an ideal guide to scientists of all backgrounds and provides a broad and thorough overview of the exciting and still-emerging field of single-molecule biology.
Author | : W. Guschlbauer |
Publisher | : Springer Science & Business Media |
Total Pages | : 289 |
Release | : 2013-06-29 |
Genre | : Science |
ISBN | : 1468453831 |
Download DNA-Ligand Interactions Book in PDF, ePub and Kindle
This volume contains the texts of the nineteen lectures presented at the NATO-ASI - FEBS Course on "DNA - ligand interactions: from drugs to proteins." The Advanced Study Institute (ASIl was held from August 30th to September 11th. 1986 in the Abbey of Fontevraud (France). The ASI was attended by 112 participants from a wide scientific horizon and from twentyone different countries. It was in some way a follow-up of the ASI held in Maratea. Italy in May 1981 and which was published in the NATO ASI Life Science series as volume 45. While much has been learned about the way the cellular machinery maintains and transmits the genetic heritage. as well as how these processes are regulated. little is Known about how the interactions between the various partners involved are taKing place. The interactions of drugs and proteins with nucleic acids are of evident importance in the understanding of these problems. The spectacular advances in recombinant DNA technology and the increased sophistication of biophysical techniques. in particular >:-ray diffraction and nuclear magnetic resonance. have created a scientific environment which is highly promising for the future of research in molecular biology. These advances permH the serious hope that biology on the molecular level may become a r-eality. Some of the contributions at the ASI presented the most recent advances in this e>:citing field.
Author | : Peter Membrey |
Publisher | : Apress |
Total Pages | : 317 |
Release | : 2011-01-27 |
Genre | : Computers |
ISBN | : 1430230525 |
Download The Definitive Guide to MongoDB Book in PDF, ePub and Kindle
MongoDB, a cross-platform NoSQL database, is the fastest-growing new database in the world. MongoDB provides a rich document-oriented structure with dynamic queries that you’ll recognize from RDBMS offerings such as MySQL. In other words, this is a book about a NoSQL database that does not require the SQL crowd to re-learn how the database world works! MongoDB has reached 1.0 and boasts 50,000+ users. The community is strong and vibrant and MongoDB is improving at a fast rate. With scalable and fast databases becoming critical for today’s applications, this book shows you how to install, administer and program MongoDB without pretending SQL never existed.
Author | : M Michael Gromiha |
Publisher | : World Scientific |
Total Pages | : 424 |
Release | : 2020-03-05 |
Genre | : Science |
ISBN | : 9811211884 |
Download Protein Interactions: Computational Methods, Analysis And Applications Book in PDF, ePub and Kindle
This book is indexed in Chemical Abstracts ServiceThe interactions of proteins with other molecules are important in many cellular activities. Investigations have been carried out to understand the recognition mechanism, identify the binding sites, analyze the the binding affinity of complexes, and study the influence of mutations on diseases. Protein interactions are also crucial in structure-based drug design.This book covers computational analysis of protein-protein, protein-nucleic acid and protein-ligand interactions and their applications. It provides up-to-date information and the latest developments from experts in the field, using illustrations to explain the key concepts and applications. This volume can serve as a single source on comparative studies of proteins interacting with proteins/DNAs/RNAs/carbohydrates and small molecules.