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Spotlight on Familial and Hereditary Gastric Cancer

Spotlight on Familial and Hereditary Gastric Cancer
Author: Giovanni Corso
Publisher: Springer Science & Business Media
Total Pages: 219
Release: 2013-06-04
Genre: Medical
ISBN: 9400765703

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In this book we have taken a comprehensive look at the subject of familial and hereditary gastric tumors. In particular, the aim of this novel editorial work is to propose the correct management of hereditary diffuse gastric cancer patients, focusing in particular on E-cadherin germline mutations, clinical criteria definition, genetic screening and molecular mechanisms, pathology and microscopic features, surgical treatment and clinical approach for asymptomatic mutation carriers. We also describe other inherited predispositions involving gastric carcinoma.


Stem Cells, Pre-neoplasia, and Early Cancer of the Upper Gastrointestinal Tract

Stem Cells, Pre-neoplasia, and Early Cancer of the Upper Gastrointestinal Tract
Author: Marnix Jansen
Publisher: Springer
Total Pages: 487
Release: 2016-08-29
Genre: Medical
ISBN: 3319413880

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This book is a comprehensive understanding of the evolution of pre-malignant disease, emphasizing common themes in the field, including stem cell biology and histologic modes of cancer progression between the distal esophagus and stomach. Its sixteen chapters discuss metaplastic tissue change in the upper GI, clonalexpansion of early neoplasia, stem cell dynamics in experimental models, pathology of early esophageal squamous cell carcinoma, therapeutic modalities for esophageal squamous cell carcinoma, pathology of Barrett’s esophagus, screening, early detection and novel diagnostic tools for Barrett's esophagus, clonal evolution of Barrett’s esophagus, endoscopic therapeutic modalities of early esophageal cancer, pathology of early gastric cancer, and experimental models for gastric cancer. Stem Cells, Pre-neoplasia and Early Cancer of the Upper Gastrointestinal Tract is an integrative text on both the current state of translational research on every cancer development of the upper gastrointestinal tract as well as on novel clinical diagnostic and therapeutic modalities. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike. Springer’s Advances in Experimental Medicine and Biology series presents multidisciplinary and dynamic findings in the broad fields of experimental medicine and biology. The wide variety in topics it presents offers readers multiple perspectives on a variety of disciplines including neuroscience, microbiology, immunology, biochemistry, biomedical engineering and cancer research.


Hereditary Gastric and Breast Cancer Syndrome

Hereditary Gastric and Breast Cancer Syndrome
Author: Giovanni Corso
Publisher: Springer Nature
Total Pages: 412
Release: 2023-03-17
Genre: Medical
ISBN: 3031213173

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In this book the editors and authors provide a comprehensive overview on basic research and clinical aspects of hereditary breast and gastric tumors. In particular, this updated editorial work aims to suggest guidelines for the clinical management of patients with hereditary diffuse gastric and lobular breast cancer. Special attention is given to E-cadherin (CDH1 gene) germline mutations, genetic screening approaches, the underlying molecular mechanisms and pathological and microscopic features. In addition, the book aims to define clinical criteria for genetic screening, and highlights current surgical treatment and clinical approaches for asymptomatic mutation carriers. Other inherited predispositions involving gastric and breast carcinoma are discussed as well. Divided into eight sections, the book starts by providing an epidemiological overview of gastric and breast cancers, followed by a section dealing with new descriptions of genetic pathways in hereditary cancer predispositions. The third section focuses on pathological features of the diseases, in an effort to bridge the gap between discovery and cancer therapy development. Subsequent sections of the book are dedicated to endoscopy and breast imaging, as well as risk-reducing surgeries to curb the risk of developing cancer. The sixth section focuses on the generation of ideas for the identification of targets and novel treatment strategies. Finally, in the seventh section the authors share the story of two patients and their experiences with the diagnosis and treatment of hereditary cancer. This multidisciplinary book brings together multiple disciplines in science and technology; specifically, medicine, surgery and biology. The majority of authors are members of the International Gastric Cancer Linkage Consortium (IGCLC) and of the European Cancer Prevention Organization (EJCPO), with relevant experience in this context. Offering in-depth insights into hereditary cancers, this book represents essential reading for students, researchers, and specialists who want to extend their knowledge on hereditary gastric and breast cancers.


Primary Care, Second Edition

Primary Care, Second Edition
Author: Joanne K. Singleton
Publisher: Springer Publishing Company
Total Pages: 1096
Release: 2014-11-12
Genre: Medical
ISBN: 0826171478

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Print+CourseSmart


Primary Care

Primary Care
Author: Robert V. DiGregorio, PharmD, BCACP
Publisher: Springer Publishing Company
Total Pages: 1096
Release: 2014-11-12
Genre: Medical
ISBN: 0826171486

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A complete, state-of-the-art bible of interprofessional primary care in one easy-to-use resource for Interprofessional Primary Care A truly interprofessional primary care textbook, created by DNPs/APRNs, MDs, PharmDs, PAs, CNSs, and CNMs Evidence-based practice guidelines for Primary Care Includes community care, team work, and wellness coachings Strong guidance on differential diagnosis, disease prevention, risk reduction and lifestyle management Across the lifespan focus PLUS gender, occupational and palliative care considerations Case Studies in PPT format available to faculty adopting the text This second edition of Primary Care delivers succinct, current, and integrated information on the assessment, differential diagnosis, treatment, and management of individuals with commonly seen conditions in primary care settings. Written and edited by APNs, MDs, PAs, PharmDs and other health professionals, it emphasizes guidance on differential diagnosis, interprofessional primary care, lifestyle management, health promotion, risk reduction, and disease prevention. The text features ërelationship-centered care, extensive coverage of age, gender, and occupational considerations; complementary approaches; nutritional assessment; violence exposure and vulnerability assessment; family, community, and cultural assessment; palliative care; and evidence-based practice guidelines. This important text presents current diagnostic criteria for each condition and includes relevant anatomy, pathology, and physiology, epidemiology of the condition, including cultural and economic factors, risk identification, and disease prevention strategies. Also included are related laboratory studies, the focused physical exam, wellness coaching, treatment options, potential pitfalls, and much more. Additionally, the book includes clinical "pearls", clinical warnings, referrals and warning points, and references. The text is of value to all interprofessional primary care providers, with a special focus on the needs of advanced practice nurses and MSN/DNP students, and as a course textbook for teaching primary health care topics New to the Second Edition: Increased focus on interprofessional primary care, including community care, team work, and wellness coaching Strong guidance on differential diagnosis, disease prevention, risk reduction and lifestyle management Broad team of interprofessional authors and editors Special focus on elder/geriatric primary care and palliative care Evidence-based practice guidelines Stronger focus on age, gender, and occupational considerationsFocus on age, gender, and occupational considerations Case Studies in PPT format available to faculty adopting the text


Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs

Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs
Author: Sundas Fayyaz
Publisher: Springer
Total Pages: 310
Release: 2018-03-07
Genre: Medical
ISBN: 3319715534

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Cancer is a multifaceted disease and overwhelmingly increasing experimental evidence has helped us to develop a deeper understanding of the role of signal transduction cascades in cancer development and progression. Tissue microarrays and next generation sequencing technologies have assisted us to gather missing pieces of jigsaw puzzle and we now know that deregulation of spatio-temporally controlled signaling cascades play fundamental role in metastasis and resistance against wide ranging therapeutics. This book offers a balanced overview of the rapidly emerging cutting edge research in molecular oncology and good source of knowledge for established oncologists, basic and medical students and pharmaceutical industry associated R&D departments.


Molecular Features Distinguishing Gastric Cancer Subtypes

Molecular Features Distinguishing Gastric Cancer Subtypes
Author: Valli De Re
Publisher: MDPI
Total Pages: 327
Release: 2018-12-07
Genre: Electronic books
ISBN: 3038974048

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This book is a printed edition of the Special Issue "Molecular Features Distinguishing Gastric Cancer Subtypes" that was published in IJMS


Spotlight on Gluten: New Symptoms for the New Millennium? Or Long-Standing Symptoms Now Being Recognized?

Spotlight on Gluten: New Symptoms for the New Millennium? Or Long-Standing Symptoms Now Being Recognized?
Author: Lucille Cholerton
Publisher: Strategic Book Publishing
Total Pages: 655
Release: 2012-02
Genre: Cooking
ISBN: 1612041108

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Lucille Cholerton is a specialist in gluten sensitivity and coeliac disease. She and her three grown children all suffer from gluten sensitivity. Read her story in Spotlight on Gluten: New symptoms for the new millennium? Or long-standing symptoms now being recognized? "Age is very pertinent to the subject of gluten sensitivity. This disorder should really be diagnosed in childhood, but if the diagnosis is missed, people can suffer for many years with unexplained symptoms, when something that they are eating every day could be the root cause of their ill health." This book covers the symptoms that Cholerton and her children suffered, and how they improved their health dramatically on a gluten-free diet. The author's research spans twenty years. "In my research I discovered that gluten may be responsible for many autoimmune disorders, of which there are some eighty-eight documented. My doctors knew nothing about this, so I really had to be my own "guinea pig." A former teacher, Lucille Cholerton is now a nutrition counselor and is writing her next books on gluten sensitivity. "There is a dire need for better diagnosis and understanding of this disorder." She is married and lives in Durban, South Africa. She started the Gluten Intolerance/Coeliac Support Group in Durban in 1995. For more information about gluten, visit http: //www.allergysa.org . Publisher's website: http: //sbpra.com/LucilleCholerton Author's Website: http: //spotlightongluten.com


Hereditary Colorectal Cancer

Hereditary Colorectal Cancer
Author: Laura Valle
Publisher: Springer
Total Pages: 494
Release: 2018-05-04
Genre: Medical
ISBN: 3319742590

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This book provides information on a wide variety of issues ranging from genetics to clinical description of the syndromes, genetic testing and counseling, and clinical management including surveillance, surgical and prophylactic interventions, and chemoprevention. Moreover, current hot issues, such as the identification of novel causal genes and the challenges we face, and the relevance of cancer risk modifiers, both genetic and environmental, are also discussed. This reference book is great for geneticists, oncologists, genetic counselors, researchers, clinicians, surgeons and nurses dedicated to, or interested in, hereditary cancer. The best and most recognized experts in the field have contributed to this project, guaranteeing updated information, accuracy and the discussion of topical issues.